ES2808728T3 - Agente terapéutico para cáncer sólido - Google Patents
Agente terapéutico para cáncer sólido Download PDFInfo
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- ES2808728T3 ES2808728T3 ES15751324T ES15751324T ES2808728T3 ES 2808728 T3 ES2808728 T3 ES 2808728T3 ES 15751324 T ES15751324 T ES 15751324T ES 15751324 T ES15751324 T ES 15751324T ES 2808728 T3 ES2808728 T3 ES 2808728T3
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014032241 | 2014-02-21 | ||
| JP2014120300 | 2014-06-11 | ||
| JP2014178953 | 2014-09-03 | ||
| PCT/JP2015/053569 WO2015125652A1 (ja) | 2014-02-21 | 2015-02-09 | 固形がんの治療剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2808728T3 true ES2808728T3 (es) | 2021-03-01 |
Family
ID=53878157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES15751324T Active ES2808728T3 (es) | 2014-02-21 | 2015-02-09 | Agente terapéutico para cáncer sólido |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20170165364A1 (enExample) |
| EP (3) | EP3132802B1 (enExample) |
| JP (3) | JP6029160B2 (enExample) |
| ES (1) | ES2808728T3 (enExample) |
| WO (1) | WO2015125652A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP6971239B2 (ja) * | 2015-10-05 | 2021-11-24 | キャリセラ バイオサイエンシーズ， インコーポレイテッド | グルタミナーゼ阻害剤とイムノオンコロジー薬剤との併用療法 |
| JP7078533B2 (ja) * | 2015-10-21 | 2022-05-31 | オーエスイー イムノセラピューティクス | 炎症促進性細胞へのマクロファージ分極を改変して癌を治療するための抗ＳＩＲＰａ化合物 |
| KR20190019121A (ko) | 2016-06-17 | 2019-02-26 | 오사카 유니버시티 | 종양 내 정맥 형성 촉진제 |
| WO2018047917A1 (ja) * | 2016-09-09 | 2018-03-15 | 国立大学法人 東京大学 | Ｈｍｇタンパク質と抗ｃｄ４抗体又は免疫チェックポイント制御剤との組み合わせによる相乗的抗腫瘍効果 |
| MX2019003683A (es) | 2016-10-11 | 2019-08-22 | Agenus Inc | Anticuerpos anti gen 3 de activación linfocítica (lag 3 ) y métodos para usarlos. |
| DK3630112T3 (da) | 2017-06-02 | 2024-04-22 | Bayer Healthcare Llc | Kombination af regorafenib og nivolumab til behandling af cancer |
| TW201938580A (zh) | 2018-03-08 | 2019-10-01 | 國立大學法人東京大學 | Ｈｍｇｎ部分肽及使用其之癌症療法 |
| GB201811291D0 (en) * | 2018-07-10 | 2018-08-29 | Univ Dublin City | A method of predicting response to treatment in cancer patients |
| CN110904045A (zh) * | 2018-09-17 | 2020-03-24 | 中国科学院动物研究所 | 经修饰的t细胞、其制备方法及用途 |
| EP4011918A4 (en) * | 2019-08-08 | 2023-08-23 | ONO Pharmaceutical Co., Ltd. | DUAL SPECIFIC PROTEIN |
| IL307974A (en) * | 2021-04-28 | 2023-12-01 | Obi Pharma Inc | Combination therapy by using akr1c3-activated compound with immune checkpoint inhibitor |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP1333850B1 (en) * | 2000-10-20 | 2008-08-20 | Genetics Institute, Inc. | Use of il-13 inhibitors for the treatment of tumors |
| AU2004217526B2 (en) * | 2003-02-28 | 2010-02-04 | St. Jude Children's Research Hospital Inc. | T cell regulation |
| EP1460088A1 (en) * | 2003-03-21 | 2004-09-22 | Biotest AG | Humanized anti-CD4 antibody with immunosuppressive properties |
| KR101498834B1 (ko) * | 2005-05-09 | 2015-03-05 | 오노 야꾸힝 고교 가부시키가이샤 | 예정 사멸 인자 1(ｐｄ-1)에 대한 인간 모노클로날 항체, 및 항-ｐｄ-1 항체를 단독 사용하거나 기타 면역 요법제와 병용한 암 치료 방법 |
| AU2009231325B2 (en) * | 2008-03-13 | 2014-09-18 | Biotest Ag | Agent for treating disease |
| US9156912B2 (en) * | 2008-12-12 | 2015-10-13 | The University Of Tokyo | Immunological reconstitution promoter or prophylactic agent for infections each of which maintains graft-versus-tumor effect |
| PL2374883T3 (pl) | 2008-12-26 | 2017-05-31 | Kyowa Hakko Kirin Co., Ltd. | Przeciwciało anty-CD4 |
| EP3798237A1 (en) * | 2010-03-05 | 2021-03-31 | The Johns Hopkins University | Compositions and methods for targeted immunomodulatory antibodies and fusion proteins |
| WO2012145183A2 (en) * | 2011-04-19 | 2012-10-26 | Pfizer Inc. | Combinations of anti-4-1bb antibodies and adcc-inducing antibodies for the treatment of cancer |
| US9676854B2 (en) * | 2011-08-15 | 2017-06-13 | Medimmune, Llc | Anti-B7-H4 antibodies and their uses |
| AR090263A1 (es) * | 2012-03-08 | 2014-10-29 | Hoffmann La Roche | Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma |
| EP3000478A4 (en) * | 2013-05-23 | 2017-03-15 | IDAC Theranostics, Inc. | Therapeutic or prophylactic agent for immunodeficiency virus infection |
| CA2937035A1 (en) * | 2014-02-05 | 2015-08-13 | Cedars-Sinai Medical Center | Methods and compositions for treating cancer and infectious diseases |
| ES2818800T3 (es) * | 2014-06-11 | 2021-04-14 | Idac Theranostics Inc | Método para reducir los efectos secundarios de un agente de control del punto de control inmunitario |
-
2015
- 2015-02-09 EP EP15751324.3A patent/EP3132802B1/en active Active
- 2015-02-09 EP EP18153989.1A patent/EP3338800A1/en not_active Ceased
- 2015-02-09 WO PCT/JP2015/053569 patent/WO2015125652A1/ja not_active Ceased
- 2015-02-09 ES ES15751324T patent/ES2808728T3/es active Active
- 2015-02-09 JP JP2016504046A patent/JP6029160B2/ja active Active
- 2015-02-09 US US15/120,427 patent/US20170165364A1/en not_active Abandoned
- 2015-02-09 EP EP18153990.9A patent/EP3338801A1/en not_active Withdrawn
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2016
- 2016-08-15 JP JP2016159348A patent/JP6578604B2/ja active Active
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2018
- 2018-12-27 US US16/234,292 patent/US20190125867A1/en not_active Abandoned
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2019
- 2019-02-15 JP JP2019025193A patent/JP7041439B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20190125867A1 (en) | 2019-05-02 |
| JPWO2015125652A1 (ja) | 2017-03-30 |
| WO2015125652A1 (ja) | 2015-08-27 |
| EP3338801A1 (en) | 2018-06-27 |
| JP2019070056A (ja) | 2019-05-09 |
| EP3132802A1 (en) | 2017-02-22 |
| JP2017014254A (ja) | 2017-01-19 |
| EP3338800A1 (en) | 2018-06-27 |
| US20170165364A1 (en) | 2017-06-15 |
| JP6578604B2 (ja) | 2019-09-25 |
| EP3132802B1 (en) | 2020-06-17 |
| JP7041439B2 (ja) | 2022-03-24 |
| JP6029160B2 (ja) | 2016-11-24 |
| EP3132802A4 (en) | 2018-04-18 |
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