ES2802123T3 - Compuestos secuestrantes de dicarbonilo dirigidos a mitocondrias - Google Patents
Compuestos secuestrantes de dicarbonilo dirigidos a mitocondrias Download PDFInfo
- Publication number
- ES2802123T3 ES2802123T3 ES14818889T ES14818889T ES2802123T3 ES 2802123 T3 ES2802123 T3 ES 2802123T3 ES 14818889 T ES14818889 T ES 14818889T ES 14818889 T ES14818889 T ES 14818889T ES 2802123 T3 ES2802123 T3 ES 2802123T3
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- Prior art keywords
- formula
- alkyl
- alkylene
- mitog
- compound
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5442—Aromatic phosphonium compounds (P-C aromatic linkage)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Dentistry (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1320636.2A GB201320636D0 (en) | 2013-11-22 | 2013-11-22 | Compounds |
| PCT/EP2014/075323 WO2015075200A1 (en) | 2013-11-22 | 2014-11-21 | Mitochondria-targeted dicarbonyl sequestering compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2802123T3 true ES2802123T3 (es) | 2021-01-15 |
Family
ID=49918047
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES14818889T Active ES2802123T3 (es) | 2013-11-22 | 2014-11-21 | Compuestos secuestrantes de dicarbonilo dirigidos a mitocondrias |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9963474B2 (enExample) |
| EP (2) | EP3623375A1 (enExample) |
| JP (1) | JP6661533B2 (enExample) |
| CN (1) | CN105873936B (enExample) |
| AU (1) | AU2014351802B2 (enExample) |
| CA (1) | CA2931000A1 (enExample) |
| ES (1) | ES2802123T3 (enExample) |
| GB (1) | GB201320636D0 (enExample) |
| HK (1) | HK1226079A1 (enExample) |
| SG (2) | SG10201807904RA (enExample) |
| WO (1) | WO2015075200A1 (enExample) |
| ZA (1) | ZA201603129B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020503280A (ja) * | 2016-12-29 | 2020-01-30 | ウニヴェルシダージ ド ポルトＵｎｉｖｅｒｓｉｄａｄｅ Ｄｏ Ｐｏｒｔｏ | ヒドロキシ安息香酸誘導体、その方法および使用 |
| JP6985730B2 (ja) * | 2017-11-17 | 2021-12-22 | 株式会社日立ハイテクサイエンス | 試料分析システム、表示方法及び試料分析方法 |
| KR101920902B1 (ko) * | 2017-12-27 | 2018-11-21 | 전남대학교 산학협력단 | 심혈관 질환 조기진단 pet 조영용 화합물 및 그의 용도 |
| WO2020036329A1 (ko) * | 2018-08-16 | 2020-02-20 | 숙명여자대학교산학협력단 | 미토콘드리아 내 nad(p)h 검출을 위한 형광 프로브 및 이를 이용한 검출방법 |
| AU2020212612B2 (en) * | 2019-01-25 | 2025-07-31 | Naji Abumrad | Triphenylphosphonium-tethered salicylamine derivatives |
| EP3914077A4 (en) * | 2019-01-25 | 2022-11-30 | Vanderbilt University | MITOCHONDRIAL TARGETING ISOKETAL/ISOLEVUGLANDIN SCAVENGERS |
| EP3925961A4 (en) * | 2019-10-30 | 2022-05-11 | Fusion Biotechnology Co., Ltd. | Mitochondria-targeting compound and composition comprising same for treating or preventing aging-related diseases |
| WO2021154877A1 (en) * | 2020-01-27 | 2021-08-05 | Vanderbilt University | Mitochondria-targeted isoketal/isolevuglandin scavengers and uses thereof |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB926998A (en) * | 1960-04-25 | 1963-05-22 | Ici Ltd | New water-soluble azo dyestuffs containing phosphonium groups |
| JPS52806A (en) | 1975-02-20 | 1977-01-06 | Dai Ichi Kogyo Seiyaku Co Ltd | Preparation of ester |
| JPS6029391B2 (ja) | 1976-02-04 | 1985-07-10 | 富士写真フイルム株式会社 | ベンゾトリアゾ−ル化合物 |
| FR2776289B1 (fr) * | 1998-03-20 | 2001-02-02 | Oreal | Composition de teinture d'oxydation contenant un coupleur cationique, procedes de teinture, nouveaux coupleurs cationiques |
| FR2776290B1 (fr) * | 1998-03-20 | 2001-08-10 | Oreal | Nouveaux composes cationiques, leur utilisation comme coupleurs pour la teinture d'oxydation des fibres keratiniques, compositions tinctoriales et procedes de teinture |
| FR2788520B1 (fr) * | 1999-01-19 | 2003-02-28 | Oreal | Nouveaux colorants mono-benzeniques cationiques, leur utilisation pour la teinture d'oxydation des fibres keratiniques, compositions tinctoriales et procedes de teinture |
| WO2002058659A1 (en) * | 2001-01-23 | 2002-08-01 | P&G-Clairol, Inc. | Couplers for oxidative coloration of hair |
| AU2003258664A1 (en) * | 2002-09-02 | 2004-03-19 | Ciba Specialty Chemicals Holding Inc. | Method of colouring porous material |
| JPWO2006059423A1 (ja) * | 2004-12-02 | 2008-06-05 | 独立行政法人科学技術振興機構 | 過興奮性の細胞傷害によって生じる疾患を治療するための薬剤および方法 |
| US7956193B2 (en) * | 2007-05-04 | 2011-06-07 | University Of South Florida | Intramolecular C-H amination with sulfonyl azides |
| CA2699794C (en) | 2007-09-10 | 2016-07-19 | University Of Massachusetts | Mitochondria-targeted anti-tumor agents |
| FR2984321A1 (fr) * | 2011-12-16 | 2013-06-21 | Oreal | Paraphenylenediamines cationiques, composition comprenant au moins de tels composes, procede de mise en oeuvre et utilisation |
| CN102617467A (zh) * | 2012-02-21 | 2012-08-01 | 大连理工大学 | 一种检测一氧化氮的超高灵敏荧光探针 |
| FR2996552B1 (fr) * | 2012-08-17 | 2016-10-14 | Oreal | Composition tinctoriale comprenant un derive o-alkyle substitue de meta-phenylenediamine cationique |
-
2013
- 2013-11-22 GB GBGB1320636.2A patent/GB201320636D0/en not_active Ceased
-
2014
- 2014-11-21 US US15/037,941 patent/US9963474B2/en not_active Expired - Fee Related
- 2014-11-21 SG SG10201807904RA patent/SG10201807904RA/en unknown
- 2014-11-21 CN CN201480063625.0A patent/CN105873936B/zh not_active Expired - Fee Related
- 2014-11-21 HK HK16114224.1A patent/HK1226079A1/zh unknown
- 2014-11-21 JP JP2016528880A patent/JP6661533B2/ja not_active Expired - Fee Related
- 2014-11-21 SG SG11201603485TA patent/SG11201603485TA/en unknown
- 2014-11-21 CA CA2931000A patent/CA2931000A1/en not_active Abandoned
- 2014-11-21 EP EP19204357.8A patent/EP3623375A1/en not_active Withdrawn
- 2014-11-21 ES ES14818889T patent/ES2802123T3/es active Active
- 2014-11-21 EP EP14818889.9A patent/EP3071582B1/en active Active
- 2014-11-21 WO PCT/EP2014/075323 patent/WO2015075200A1/en not_active Ceased
- 2014-11-21 AU AU2014351802A patent/AU2014351802B2/en not_active Ceased
-
2016
- 2016-05-10 ZA ZA2016/03129A patent/ZA201603129B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2931000A1 (en) | 2015-05-28 |
| EP3623375A1 (en) | 2020-03-18 |
| AU2014351802B2 (en) | 2019-10-03 |
| WO2015075200A1 (en) | 2015-05-28 |
| CN105873936A (zh) | 2016-08-17 |
| GB201320636D0 (en) | 2014-01-08 |
| CN105873936B (zh) | 2018-09-14 |
| ZA201603129B (en) | 2018-12-19 |
| US20160289252A1 (en) | 2016-10-06 |
| AU2014351802A1 (en) | 2016-05-26 |
| NZ719705A (en) | 2021-09-24 |
| EP3071582A1 (en) | 2016-09-28 |
| EP3071582B1 (en) | 2020-04-29 |
| HK1226079A1 (zh) | 2017-09-22 |
| US9963474B2 (en) | 2018-05-08 |
| JP6661533B2 (ja) | 2020-03-11 |
| SG10201807904RA (en) | 2018-10-30 |
| JP2017504561A (ja) | 2017-02-09 |
| SG11201603485TA (en) | 2016-05-30 |
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