ES2796973T3 - Métodos y composiciones para reducir el crecimiento, la migración y la invasividad de células madre de cáncer cerebral y mejorar la supervivencia de pacientes con tumores cerebrales - Google Patents
Métodos y composiciones para reducir el crecimiento, la migración y la invasividad de células madre de cáncer cerebral y mejorar la supervivencia de pacientes con tumores cerebrales Download PDFInfo
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
Landscapes
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US201462090029P | 2014-12-10 | 2014-12-10 | |
| PCT/IB2015/002577 WO2016092378A1 (en) | 2014-12-10 | 2015-12-09 | Methods and compositions for reducing growth, migration and invasiveness of brain cancer stem cells and improving survival of patients with brian tumors |
Publications (1)
| Publication Number | Publication Date |
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| ES2796973T3 true ES2796973T3 (es) | 2020-11-30 |
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| Country | Link |
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| US (2) | US10688167B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3229831B1 (cg-RX-API-DMAC7.html) |
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| KR (1) | KR102674191B1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2015359043C1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2970140A1 (cg-RX-API-DMAC7.html) |
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| ES (1) | ES2796973T3 (cg-RX-API-DMAC7.html) |
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| US10852069B2 (en) | 2010-05-04 | 2020-12-01 | Fractal Heatsink Technologies, LLC | System and method for maintaining efficiency of a fractal heat sink |
| KR102674191B1 (ko) * | 2014-12-10 | 2024-06-11 | 하이퍼스템 에스에이 | 뇌암 줄기 세포의 성장, 이동 및 침습성 감소 그리고 뇌종양을 가진 환자의 생존 개선 방법 및 조성물 |
| US20210008149A1 (en) * | 2017-10-25 | 2021-01-14 | Wntresearch Ab | Wnt5a peptides in reduction of cancer stem cells |
| KR101921836B1 (ko) | 2017-11-23 | 2018-11-26 | 서울대학교병원 | 피부성체 줄기세포의 분화 조절 방법, 및 피부성체 줄기세포의 분화 조절용 조성물 및 키트 |
| US20210041443A1 (en) * | 2018-04-24 | 2021-02-11 | Universidade Do Minho | Wnt6 as glioblastoma oncogenic biomarker, and uses of inhibitors thereof |
| EP3613757A1 (en) | 2018-08-20 | 2020-02-26 | Wntresearch AB | Solution phase routes for wnt hexapeptides |
| EP3666789A1 (en) * | 2018-12-14 | 2020-06-17 | Wntresearch AB | Linear solution phase routes for wnt hexapeptides |
| BR112021020635A2 (pt) * | 2019-04-16 | 2022-02-22 | Wntresearch Ab | Peptídeo wnt5a ou derivados do mesmo em combinação com um ou mais inibidores de ponto de controle para uso no tratamento do câncer de cólon, câncer colorretal ou câncer de mama |
| WO2021034784A1 (en) | 2019-08-16 | 2021-02-25 | Poltorak Technologies, LLC | Device and method for medical diagnostics |
| CN114081954B (zh) * | 2021-10-30 | 2023-02-28 | 中国人民解放军陆军军医大学第一附属医院 | 用于胶质母细胞瘤治疗的药物组合物以及预后的诊断试剂 |
| WO2025088835A1 (ja) * | 2023-10-25 | 2025-05-01 | 国立大学法人大阪大学 | ヒト化抗ｃｋａｐ４抗体又はその抗原結合性断片 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1521000A (en) | 1975-06-13 | 1978-08-09 | Syntex Puerto Rico Inc | Inhalation device |
| US4192309A (en) | 1978-09-05 | 1980-03-11 | Syntex Puerto Rico, Inc. | Inhalation device with capsule opener |
| US4227522A (en) | 1978-09-05 | 1980-10-14 | Syntex Puerto Rico, Inc. | Inhalation device |
| FR2550452B1 (fr) | 1982-10-08 | 1992-05-22 | Glaxo Group Ltd | Dispositif pour administrer des medicaments a des patients |
| US4778054A (en) | 1982-10-08 | 1988-10-18 | Glaxo Group Limited | Pack for administering medicaments to patients |
| FI88112C (fi) | 1985-07-30 | 1993-04-13 | Glaxo Group Ltd | Anordning foer administrering av laekemedel till patienter |
| JPH05963A (ja) | 1990-04-13 | 1993-01-08 | Toray Ind Inc | ポリペプチド類組成物 |
| US6582728B1 (en) | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| EP1226172A1 (en) * | 1999-11-05 | 2002-07-31 | Forskarpatent i Syd AB | Compounds, antibodies and methods for treating, preventing or diagnosing tumour metastasis |
| WO2006130082A1 (en) | 2005-05-30 | 2006-12-07 | Forskarpatent I Syd Ab | A peptide ligand to impair cancer cell migration |
| RU2517190C2 (ru) * | 2008-08-13 | 2014-05-27 | Внтрисерч Аб | Применение производных пептида wnt5-a для лечения меланомы и рака желудка |
| EP2523974A4 (en) | 2010-01-12 | 2013-11-06 | Oncomed Pharm Inc | WNT BINDING AGENTS AND USES THEREOF |
| EP2446895A1 (en) * | 2010-10-01 | 2012-05-02 | Stemgen S.P.A. | EPH receptor expression in tumor stem cells |
| US9278119B2 (en) * | 2011-07-01 | 2016-03-08 | Wntresearch Ab | Treatment of prostate cancer and a method for determining the prognosis for prostate cancer patients |
| US20140171356A1 (en) | 2012-12-12 | 2014-06-19 | The Board Of Trustees Of The Leland Stanford Junior University | Chemically immobilized wnt protein and methods of use |
| KR102674191B1 (ko) * | 2014-12-10 | 2024-06-11 | 하이퍼스템 에스에이 | 뇌암 줄기 세포의 성장, 이동 및 침습성 감소 그리고 뇌종양을 가진 환자의 생존 개선 방법 및 조성물 |
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| KR102674191B1 (ko) | 2024-06-11 |
| EP3229831B1 (en) | 2020-03-11 |
| JP6921755B2 (ja) | 2021-08-18 |
| US10688167B2 (en) | 2020-06-23 |
| EP3229831A1 (en) | 2017-10-18 |
| KR20170098861A (ko) | 2017-08-30 |
| AU2015359043B2 (en) | 2021-09-02 |
| AU2015359043C1 (en) | 2022-01-06 |
| NZ732532A (en) | 2024-10-25 |
| CA2970140A1 (en) | 2016-06-16 |
| AU2015359043A1 (en) | 2017-06-29 |
| WO2016092378A1 (en) | 2016-06-16 |
| US11357840B2 (en) | 2022-06-14 |
| US20200345821A1 (en) | 2020-11-05 |
| US20170368158A1 (en) | 2017-12-28 |
| DK3229831T3 (da) | 2020-06-15 |
| JP2018500390A (ja) | 2018-01-11 |
| HK1245152A1 (en) | 2018-08-24 |
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