ES2781433T3 - Partículas de glicina, así como procedimiento para su preparación y su uso - Google Patents

Partículas de glicina, así como procedimiento para su preparación y su uso Download PDF

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Publication number
ES2781433T3
ES2781433T3 ES17701268T ES17701268T ES2781433T3 ES 2781433 T3 ES2781433 T3 ES 2781433T3 ES 17701268 T ES17701268 T ES 17701268T ES 17701268 T ES17701268 T ES 17701268T ES 2781433 T3 ES2781433 T3 ES 2781433T3
Authority
ES
Spain
Prior art keywords
glycine
grain size
granules
powder
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES17701268T
Other languages
English (en)
Spanish (es)
Inventor
Harald Benk
Gudrun Birk
Melina Decker
Dieter Lubda
Guenter Moddelmog
Harald Muessig
Tanino Scaramuzza
Michael Schleehahn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Application granted granted Critical
Publication of ES2781433T3 publication Critical patent/ES2781433T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/22Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by pressing in moulds or between rollers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Fodder In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Detergent Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
ES17701268T 2016-02-23 2017-01-24 Partículas de glicina, así como procedimiento para su preparación y su uso Active ES2781433T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16000431 2016-02-23
PCT/EP2017/000078 WO2017144149A1 (de) 2016-02-23 2017-01-24 Glycin-partikel

Publications (1)

Publication Number Publication Date
ES2781433T3 true ES2781433T3 (es) 2020-09-02

Family

ID=55628703

Family Applications (1)

Application Number Title Priority Date Filing Date
ES17701268T Active ES2781433T3 (es) 2016-02-23 2017-01-24 Partículas de glicina, así como procedimiento para su preparación y su uso

Country Status (14)

Country Link
US (1) US11174218B2 (ja)
EP (1) EP3419606B1 (ja)
JP (1) JP7137479B2 (ja)
KR (1) KR20180115781A (ja)
CN (1) CN108697647B (ja)
AU (1) AU2017222125B2 (ja)
BR (1) BR112018016634B1 (ja)
DK (1) DK3419606T3 (ja)
ES (1) ES2781433T3 (ja)
MX (1) MX2018010049A (ja)
PH (1) PH12018501372A1 (ja)
PT (1) PT3419606T (ja)
SG (1) SG11201807106WA (ja)
WO (1) WO2017144149A1 (ja)

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK483975A (da) 1975-06-10 1976-12-11 Uniscope Inc Fremgangsmade til komprimering af et partikelformet produkt til piller eller lignende sammenhengende formlegemer samt smore- eller bindemiddel til anvendelse ved udovelse af fremgangsmaden
JPS5879917A (ja) * 1981-11-09 1983-05-13 Showa Denko Kk グリシン錠剤の成形方法
AU1193092A (en) * 1992-01-10 1993-08-03 Obschestvo S Ogranichennoi Otvetstvennostju Meditsinsky Nauchno-Proizvodstvenny Komplex Biotiki Granulated pharmaceutical composition and method of obtaining it
GB9612629D0 (en) 1996-06-17 1996-08-21 Oxford Biosciences Ltd Method for providing dense particle compositions for use in transdermal particle delivery
US6893664B1 (en) 1996-06-17 2005-05-17 Powderject Research Limited Particle delivery techniques
JPH11276553A (ja) 1998-03-26 1999-10-12 Jgc Corp 固形製剤の製造方法およびそのための製造装置
JP2000198858A (ja) 1998-11-05 2000-07-18 Mitsui Chemicals Inc 架橋ポリアミノ酸含有粒子
KR20020053559A (ko) * 2000-12-27 2002-07-05 김경재 스테비오사이드를 이용한 가정용 감미료의 제조방법
JPWO2004016262A1 (ja) 2002-08-12 2005-12-02 協和醗酵工業株式会社 アミノ酸含有チュアブル錠
JP2004269384A (ja) 2003-03-06 2004-09-30 Kyowa Hakko Kogyo Co Ltd 吸水性アミノ酸被覆顆粒
DE102005025283A1 (de) * 2005-06-02 2006-12-07 Bayer Healthcare Ag Stabiler Wirkstoffkomplex von Salzen der o-Acetylsalicylsäure mit basischen Aminosäuren und Glycin
JP5582033B2 (ja) * 2008-09-09 2014-09-03 味の素株式会社 分岐鎖アミノ酸含有経口製剤
RU2519760C1 (ru) * 2013-01-25 2014-06-20 Николай Борисович Леонидов Антиоксидант и способ его получения
JP6384068B2 (ja) 2013-03-21 2018-09-05 味の素株式会社 アミノ酸含有顆粒及びその製造方法
WO2016091349A1 (en) * 2014-12-11 2016-06-16 Merck Patent Gmbh Cell culture media

Also Published As

Publication number Publication date
JP7137479B2 (ja) 2022-09-14
MX2018010049A (es) 2018-11-09
WO2017144149A1 (de) 2017-08-31
PH12018501372A1 (en) 2019-02-18
AU2017222125A1 (en) 2018-10-11
SG11201807106WA (en) 2018-09-27
BR112018016634A2 (pt) 2018-12-26
DK3419606T3 (da) 2020-03-16
EP3419606B1 (de) 2019-12-25
BR112018016634B1 (pt) 2023-11-21
US11174218B2 (en) 2021-11-16
JP2019507670A (ja) 2019-03-22
AU2017222125B2 (en) 2022-07-14
PT3419606T (pt) 2020-03-27
CN108697647B (zh) 2022-04-05
EP3419606A1 (de) 2019-01-02
CN108697647A (zh) 2018-10-23
US20190047942A1 (en) 2019-02-14
KR20180115781A (ko) 2018-10-23

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