ES2761854T3 - Usos de albúmina de suero recombinante obtenida a partir de levadura - Google Patents

Usos de albúmina de suero recombinante obtenida a partir de levadura Download PDF

Info

Publication number
ES2761854T3
ES2761854T3 ES17786853T ES17786853T ES2761854T3 ES 2761854 T3 ES2761854 T3 ES 2761854T3 ES 17786853 T ES17786853 T ES 17786853T ES 17786853 T ES17786853 T ES 17786853T ES 2761854 T3 ES2761854 T3 ES 2761854T3
Authority
ES
Spain
Prior art keywords
stem cells
medium
storage medium
hours
yeast
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES17786853T
Other languages
English (en)
Spanish (es)
Inventor
Eva Balslev Jørgensen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Albumedix Ltd
Original Assignee
Albumedix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Albumedix Ltd filed Critical Albumedix Ltd
Application granted granted Critical
Publication of ES2761854T3 publication Critical patent/ES2761854T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/128—Chemically defined matrices for immobilising, holding or storing living parts, e.g. alginate gels; Chemically altering living parts, e.g. by cross-linking
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/125—Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/04—Preserving or maintaining viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0635—B lymphocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/16—Physical preservation processes
    • A01N1/162—Temperature processes, e.g. following predefined temperature changes over time
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/34—Sugars
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/38—Vitamins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Reproductive Health (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Dispersion Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ES17786853T 2016-10-04 2017-10-04 Usos de albúmina de suero recombinante obtenida a partir de levadura Active ES2761854T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16192276 2016-10-04
PCT/EP2017/075257 WO2018065491A1 (en) 2016-10-04 2017-10-04 Uses of recombinant yeast-derived serum albumin

Publications (1)

Publication Number Publication Date
ES2761854T3 true ES2761854T3 (es) 2020-05-21

Family

ID=57047137

Family Applications (1)

Application Number Title Priority Date Filing Date
ES17786853T Active ES2761854T3 (es) 2016-10-04 2017-10-04 Usos de albúmina de suero recombinante obtenida a partir de levadura

Country Status (7)

Country Link
US (1) US20190216079A1 (https=)
EP (3) EP3429345B1 (https=)
JP (2) JP6928084B2 (https=)
KR (2) KR102662031B1 (https=)
DK (1) DK3429345T3 (https=)
ES (1) ES2761854T3 (https=)
WO (1) WO2018065491A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3847246A1 (en) 2018-09-06 2021-07-14 Bavarian Nordic A/S Storage improved poxvirus compositions
NZ783290A (en) 2019-06-11 2026-02-27 Axogen Corp Wet preservation of tissue
EP4069200A1 (en) 2019-12-04 2022-10-12 Albumedix Ltd Methods and compositions produced thereby
US20230114464A1 (en) 2020-03-12 2023-04-13 Bavarian Nordic A/S Conditions Improving Poxvirus Stability
CN113549653B (zh) * 2020-04-23 2024-03-22 上海赛比曼生物科技有限公司 用于慢病毒载体长期存贮的组合试剂
AU2021326232A1 (en) * 2020-08-11 2023-04-13 Shenzhen Protgen Ltd. Young and undamaged human serum albumin improves longevity of human
JP7280623B2 (ja) * 2020-12-28 2023-05-24 株式会社アビー 細胞凍結保存液、及び細胞凍結方法
JP7318983B2 (ja) * 2021-12-21 2023-08-01 株式会社アビー 細胞凍結保存液、及び細胞凍結方法
EP4558516B1 (en) 2022-07-18 2025-08-13 Yeda Research and Development Co. Ltd Albumin protein variants, production thereof and uses of same
CN117783501B (zh) * 2024-02-26 2024-05-10 四川大学华西第二医院 辛酸钠在注意缺陷与多动障碍中的应用及产品
WO2026074121A1 (en) 2024-10-02 2026-04-09 Sartorius Albumedix Limited Albumin formulations and uses thereof

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5728553A (en) 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
FR2746109B1 (fr) * 1996-03-12 1998-04-17 Rhone Poulenc Rorer Sa Milieu pour la conservation de materiel biologique
GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
JP4798833B2 (ja) 2000-10-24 2011-10-19 一般財団法人化学及血清療法研究所 加熱処理工程を含むヒト血清アルブミンの製造方法
DE60121196T2 (de) 2000-10-24 2007-07-12 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Verfahren zur monomerisierung von humanen serumalbumin-polymeren
JP4798832B2 (ja) 2000-10-24 2011-10-19 一般財団法人化学及血清療法研究所 ヒト血清アルブミン多量体の除去方法
JP2004238392A (ja) * 2003-01-14 2004-08-26 Nipro Corp 安定化された蛋白質性製剤
GB0310347D0 (en) 2003-05-07 2003-06-11 Delta Biotechnology Ltd Assay
JP4644604B2 (ja) 2004-01-20 2011-03-02 一般財団法人化学及血清療法研究所 ２価陽イオン存在下加熱処理によるヒト血清アルブミンの製造方法
EP2210608B1 (en) * 2007-11-02 2016-08-31 JCR Pharmaceuticals CO., LTD. Pharmaceutical composition containing human mesenchymal stem cell
KR101722961B1 (ko) 2009-02-11 2017-04-04 알부메딕스 에이/에스 알부민 변이체 및 접합체
DK2427486T3 (en) * 2009-05-07 2015-05-26 Novozymes Biopharma Dk As A process for purifying albumin
CA2776241A1 (en) 2009-10-30 2011-05-05 Novozymes Biopharma Dk A/S Albumin variants
US8609416B2 (en) * 2009-12-18 2013-12-17 Ventria Bioscience Methods and compositions comprising heat shock proteins
JP2013517776A (ja) * 2010-01-25 2013-05-20 ベントリア・バイオサイエンス タンパク質の生成を改善するための方法および組成物
US10233228B2 (en) 2010-04-09 2019-03-19 Albumedix Ltd Albumin derivatives and variants
JP6247210B2 (ja) 2011-07-05 2017-12-13 アルブミディクス アクティーゼルスカブ アルブミン製剤及び用途
US9458424B2 (en) * 2013-12-19 2016-10-04 FertiPro N.V. Methods for cryopreservation of stem cells via slow-freezing

Also Published As

Publication number Publication date
CA3038422A1 (en) 2018-04-12
EP3791719A1 (en) 2021-03-17
KR102573478B1 (ko) 2023-09-04
US20190216079A1 (en) 2019-07-18
JP7249387B2 (ja) 2023-03-30
WO2018065491A1 (en) 2018-04-12
EP3429345B1 (en) 2019-09-11
JP2021176336A (ja) 2021-11-11
KR102662031B1 (ko) 2024-05-03
JP6928084B2 (ja) 2021-09-01
DK3429345T3 (da) 2019-11-25
EP3429345A1 (en) 2019-01-23
KR20190052075A (ko) 2019-05-15
KR20230128591A (ko) 2023-09-05
EP3603391A1 (en) 2020-02-05
JP2019533442A (ja) 2019-11-21

Similar Documents

Publication Publication Date Title
ES2761854T3 (es) Usos de albúmina de suero recombinante obtenida a partir de levadura
US11485953B2 (en) Compositions and methods for maintaining cell viability
JP6879949B2 (ja) 治療目的のための細胞の凍結保存方法
Monsel et al. Mesenchymal stem cell derived secretome and extracellular vesicles for acute lung injury and other inflammatory lung diseases
US10104881B2 (en) Composition comprising plant-derived recombinant human serum albumin, lipids, and plant protein hydrolysates as active ingredients for cryopreservation of stem cells or primary cells
ES2708999T3 (es) Solución que contiene trehalosa y dextrano para el trasplante celular de mamíferos
ES2810098T3 (es) Preparación liofilizada de toxina botulínica
ES2948612T3 (es) Formulaciones de ADAMTS13 líquidas y liofilizadas estabilizadas
KR101960729B1 (ko) 감소된 수준의 용존 산소를 갖는 인간 알부민을 제조하는 방법
EP2598660A4 (en) COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN BLOOD AND OTHER BIODEGRADS DURING TRANSPORT AND STORAGE IN AMBIENT TEMPERATURES
KR101407355B1 (ko) 식물 유래의 재조합 인간 혈청 알부민, 지질 및 식물 단백질 가수분해물을 유효성분으로 포함하는 줄기세포 또는 일차배양세포의 동결보존용 조성물
KR20140014318A (ko) 세포 보존용 수용액
AU2021273656A1 (en) Extracellular matrix composition beads for cell culture
Mahiddine et al. Conditioned medium from canine amniotic membrane-derived mesenchymal stem cells improved dog sperm post-thaw quality-related parameters
TW201821610A (zh) 哺乳動物細胞凍結保存液
TW202043452A (zh) 細胞冷凍保存液
EP1820847B1 (en) Composition for cell frozen-storage
WO2022261716A1 (en) Aqueous formulations for preservation of extracellular vesicles
JP2021532833A (ja) 細胞および／または組織の輸送用組成物および／または凍結保存用組成物
CA3038422C (en) Uses of recombinant yeast-derived serum albumin
HK40048841A (en) Uses of recombinant yeast-derived serum albumin
WO2018215684A1 (es) Medios de cultivo con lisados plaquetarios
KR102867614B1 (ko) 콜라겐 가수분해물을 포함하는 냉동보존 제형