ES2749433T3

ES2749433T3 - Apremilast para el tratamiento de una enfermedad hepática o una anomalía de la función hepática

Apremilast para el tratamiento de una enfermedad hepática o una anomalía de la función hepática Download PDF

Info

Publication number: ES2749433T3
Authority: ES; Spain
Prior art keywords: compound; methoxyphenyl; ethoxy; dione; methylsulfonylethyl
Prior art date: 2014-06-23
Legal status : Active

Application number

ES15739070T

Other languages

English (en)

Spanish (es)

Inventor

Douglas Hough

Randall Stevens

Current Assignee

Celgene Corp

Original Assignee

Celgene Corp

Priority date

2014-06-23

Filing date

2015-06-22

Publication date

2020-03-20

2015-06-22 Application filed by Celgene Corp filed Critical Celgene Corp

2020-03-20 Application granted granted Critical

2020-03-20 Publication of ES2749433T3 publication Critical patent/ES2749433T3/es

Status Active legal-status Critical Current

2035-06-22 Anticipated expiration legal-status Critical

Links

IMOZEMNVLZVGJZ-QGZVFWFLSA-N apremilast Chemical compound C1=C(OC)C(OCC)=CC([C@@H](CS(C)(=O)=O)N2C(C3=C(NC(C)=O)C=CC=C3C2=O)=O)=C1 IMOZEMNVLZVGJZ-QGZVFWFLSA-N 0.000 title claims abstract description 86
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IMOZEMNVLZVGJZ-UHFFFAOYSA-N n-[2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide Chemical compound C1=C(OC)C(OCC)=CC(C(CS(C)(=O)=O)N2C(C3=C(NC(C)=O)C=CC=C3C2=O)=O)=C1 IMOZEMNVLZVGJZ-UHFFFAOYSA-N 0.000 claims abstract description 67
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