ES2742898T3 - Composiciones de protrombina humana y factor X activado para mejorar la hemostasia en el tratamiento de trastornos hemorrágicos - Google Patents
Composiciones de protrombina humana y factor X activado para mejorar la hemostasia en el tratamiento de trastornos hemorrágicos Download PDFInfo
- Publication number
- ES2742898T3 ES2742898T3 ES15712018T ES15712018T ES2742898T3 ES 2742898 T3 ES2742898 T3 ES 2742898T3 ES 15712018 T ES15712018 T ES 15712018T ES 15712018 T ES15712018 T ES 15712018T ES 2742898 T3 ES2742898 T3 ES 2742898T3
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- Prior art keywords
- fii
- fxa
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- composition
- hemophilia
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4833—Thrombin (3.4.21.5)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/54—Mixtures of enzymes or proenzymes covered by more than a single one of groups A61K38/44 - A61K38/46 or A61K38/51 - A61K38/53
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21005—Thrombin (3.4.21.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21006—Coagulation factor Xa (3.4.21.6)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461953496P | 2014-03-14 | 2014-03-14 | |
| PCT/US2015/020361 WO2015138847A1 (en) | 2014-03-14 | 2015-03-13 | Compositions of human prothrombin and activated factor x for improving hemostasis in the treatment of bleeding disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2742898T3 true ES2742898T3 (es) | 2020-02-17 |
Family
ID=52727470
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES15712018T Active ES2742898T3 (es) | 2014-03-14 | 2015-03-13 | Composiciones de protrombina humana y factor X activado para mejorar la hemostasia en el tratamiento de trastornos hemorrágicos |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20150258182A1 (enExample) |
| EP (1) | EP3116534B1 (enExample) |
| JP (1) | JP6535036B2 (enExample) |
| CN (1) | CN106413744B (enExample) |
| AU (1) | AU2015229222C1 (enExample) |
| ES (1) | ES2742898T3 (enExample) |
| NZ (1) | NZ724105A (enExample) |
| TW (1) | TWI653047B (enExample) |
| WO (1) | WO2015138847A1 (enExample) |
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| TWI653047B (zh) | 2014-03-14 | 2019-03-11 | 百特製藥公司 | 用於在出血性病症的治療中促進止血的人類凝血酶原及活化因子x的組成物 |
| JP7227905B2 (ja) | 2017-02-09 | 2023-02-22 | ツェー・エス・エル・ベーリング・ゲー・エム・ベー・ハー | 出血の処置または予防における使用のための血液凝固因子代替製品 |
| EP3590528A1 (en) * | 2018-07-06 | 2020-01-08 | Octapharma AG | Fx activation process and its use in the preparation of a fxa composition |
| MX2024008243A (es) | 2021-12-30 | 2024-09-04 | Baxter Int | Soluciones de fibrinogeno y trombina para un sellador de fibrina y un kit de sellador de fibrina. |
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| US4287180A (en) | 1980-01-28 | 1981-09-01 | Baxter Travenol Laboratories, Inc. | Method for treating blood clotting factor inhibitors |
| HUP9700603A3 (en) * | 1996-03-20 | 2001-08-28 | Baxter Ag | Pharmaceutical preparation for the treatment of blood coagulation disorders |
| US9956272B2 (en) | 2007-05-30 | 2018-05-01 | Bio Products Laboratory Limited | Methods for preparing factor X, activated factor X, inactivated factor X and inactivated factor Xa, and pharmaceutical compositions comprising same |
| CA2790248A1 (en) * | 2010-03-15 | 2011-09-22 | Ferrosan Medical Devices A/S | A method for promotion of hemostasis and/or wound healing |
| TWI653047B (zh) | 2014-03-14 | 2019-03-11 | 百特製藥公司 | 用於在出血性病症的治療中促進止血的人類凝血酶原及活化因子x的組成物 |
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2015
- 2015-03-12 TW TW104107965A patent/TWI653047B/zh active
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- 2015-03-13 CN CN201580022141.6A patent/CN106413744B/zh active Active
- 2015-03-13 NZ NZ724105A patent/NZ724105A/en unknown
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2018
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| AU2015229222B2 (en) | 2020-08-27 |
| TW201620545A (zh) | 2016-06-16 |
| US20190231855A1 (en) | 2019-08-01 |
| JP2017508806A (ja) | 2017-03-30 |
| EP3116534A1 (en) | 2017-01-18 |
| TWI653047B (zh) | 2019-03-11 |
| JP6535036B2 (ja) | 2019-06-26 |
| AU2015229222C1 (en) | 2020-12-24 |
| WO2015138847A1 (en) | 2015-09-17 |
| AU2015229222A1 (en) | 2016-09-29 |
| CN106413744B (zh) | 2020-09-04 |
| US20150258182A1 (en) | 2015-09-17 |
| CN106413744A (zh) | 2017-02-15 |
| US11160850B2 (en) | 2021-11-02 |
| NZ724105A (en) | 2023-02-24 |
| EP3116534B1 (en) | 2019-05-29 |
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