ES2712608T3 - Péptidos autoensamblantes para el tratamiento de las bullas pulmonares - Google Patents

Péptidos autoensamblantes para el tratamiento de las bullas pulmonares Download PDF

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Publication number
ES2712608T3
ES2712608T3 ES15712233T ES15712233T ES2712608T3 ES 2712608 T3 ES2712608 T3 ES 2712608T3 ES 15712233 T ES15712233 T ES 15712233T ES 15712233 T ES15712233 T ES 15712233T ES 2712608 T3 ES2712608 T3 ES 2712608T3
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ES
Spain
Prior art keywords
solution
self
peptide
assembling peptide
target area
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES15712233T
Other languages
English (en)
Spanish (es)
Inventor
Manav Mehta
Hisashi Tsukada
Eun Gil
Karl Gilbert
Satoru Kobayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3D Matrix Ltd
Original Assignee
3D Matrix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Publication of ES2712608T3 publication Critical patent/ES2712608T3/es
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/34Trocars; Puncturing needles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/04Tracheal tubes
    • A61M16/0463Tracheal tubes combined with suction tubes, catheters or the like; Outside connections
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
ES15712233T 2014-03-10 2015-03-10 Péptidos autoensamblantes para el tratamiento de las bullas pulmonares Active ES2712608T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461950529P 2014-03-10 2014-03-10
US201461953049P 2014-03-14 2014-03-14
PCT/US2015/019743 WO2015138478A1 (en) 2014-03-10 2015-03-10 Autoassembling peptides for the treatment of pulmonary bulla

Publications (1)

Publication Number Publication Date
ES2712608T3 true ES2712608T3 (es) 2019-05-14

Family

ID=52737415

Family Applications (1)

Application Number Title Priority Date Filing Date
ES15712233T Active ES2712608T3 (es) 2014-03-10 2015-03-10 Péptidos autoensamblantes para el tratamiento de las bullas pulmonares

Country Status (5)

Country Link
US (1) US10245299B2 (enExample)
EP (1) EP3116524B1 (enExample)
JP (1) JP6545727B2 (enExample)
ES (1) ES2712608T3 (enExample)
WO (1) WO2015138478A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0920030B1 (pt) 2008-10-06 2019-03-26 3-D Matrix, Ltd. Agente de oclusão do tecido, agentes hemostáticos, preventivos e de oclusão ou escleroterapia relacionados, e infusão do tecido mucosal
EP2869903B1 (en) 2012-07-06 2018-11-28 3-D Matrix Ltd. Fill-finish process for peptide solutions
ES2706492T3 (es) * 2014-03-10 2019-03-29 3 D Matrix Ltd Péptidos de autoensamblaje como agentes para la obstrucción bronquial
CN106456811B (zh) 2014-03-10 2021-04-02 三维矩阵有限责任公司 肽组合物的灭菌和过滤
EP3116524B1 (en) 2014-03-10 2018-11-28 3-D Matrix Ltd. Autoassembling peptides for the treatment of pulmonary bulla
CN106459154A (zh) 2014-03-10 2017-02-22 三维矩阵有限责任公司 自组装肽组合物
WO2017120092A1 (en) * 2016-01-06 2017-07-13 3-D Matrix, Ltd. Combination compositions
CN106539561B (zh) * 2016-12-09 2023-08-11 中国科学院西安光学精密机械研究所 一种肺大泡破裂部位定位装置
CN111712230B (zh) 2017-12-15 2024-04-26 立美基股份有限公司 表面活性剂肽纳米结构及在药物递送中的用途
JP7442196B2 (ja) 2018-07-03 2024-03-04 株式会社スリー・ディー・マトリックス イオン性自己組織化ペプチド
EP4125995A4 (en) 2020-03-31 2024-04-10 3-D Matrix, Ltd. STERILIZATION OF SELF-ASSEMBLY PEPTIDES BY IRRADIATION
WO2022035782A2 (en) * 2020-08-10 2022-02-17 Gel4Med, Inc. Antimicrobial matrix formed from peptide hydrogels
WO2022035783A2 (en) * 2020-08-10 2022-02-17 Gel4Med, Inc. Topical and parenteral use and administration of self-assembling amphiphilic peptide hydrogels

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582640A (en) 1982-03-08 1986-04-15 Collagen Corporation Injectable cross-linked collagen implant material
US4466641A (en) 1982-08-04 1984-08-21 The Lockformer Company Duct connecting system
US4642117A (en) 1985-03-22 1987-02-10 Collagen Corporation Mechanically sheared collagen implant material and method
US4947840A (en) 1987-08-21 1990-08-14 Massachusetts Institute Of Technology Biodegradable templates for the regeneration of tissues
US5236903A (en) 1988-06-24 1993-08-17 Ichiro Azuma Polypeptide comprising repeated cell-adhesive core sequences
US5110604A (en) 1988-06-30 1992-05-05 Collagen Corporation Processes for producing collagen matrixes and methods of using same
US5126141A (en) 1988-11-16 1992-06-30 Mediventures Incorporated Composition and method for post-surgical adhesion reduction with thermo-irreversible gels of polyoxyalkylene polymers and ionic polysaccharides
US5550187A (en) 1988-11-21 1996-08-27 Collagen Corporation Method of preparing crosslinked biomaterial compositions for use in tissue augmentation
US5629291A (en) 1992-01-31 1997-05-13 La Jolla Cancer Research Foundation Methods of modulating fibronectin extracellular matrix assembly
US5292514A (en) 1992-06-24 1994-03-08 Minnesota Mining And Manufacturing Company Azlactone-functional substrates, corneal prostheses, and manufacture and use thereof
US5670483A (en) 1992-12-28 1997-09-23 Massachusetts Insititute Of Technology Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor
US5955343A (en) 1992-12-28 1999-09-21 Massachusetts Institute Of Technology Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor
GB2274988A (en) 1993-02-10 1994-08-17 Mcconn Stern Rita Iodine containing wound-healing preparations
US5709854A (en) 1993-04-30 1998-01-20 Massachusetts Institute Of Technology Tissue formation by injecting a cell-polymeric solution that gels in vivo
US5773577A (en) 1994-03-03 1998-06-30 Protein Polymer Technologies Products comprising substrates capable of enzymatic cross-linking
US5527610A (en) 1994-05-20 1996-06-18 The Uab Research Foundation Elastomeric polypeptide matrices for preventing adhesion of biological materials
US5510102A (en) 1995-01-23 1996-04-23 The Regents Of The University Of California Plasma and polymer containing surgical hemostatic adhesives
WO1996040033A1 (en) 1995-06-07 1996-12-19 Clarion Pharmaceuticals Inc. Non-biological patch for hemostasis
RU2193897C2 (ru) 1996-04-04 2002-12-10 Бакстер Акциенгезельшафт Гемостатическая губка, основанная на коллагене, способ ее получения, повязка для ран, включающая такую губку, и набор для приготовления повязки для ран
US6489446B1 (en) 1996-08-07 2002-12-03 Hsc Research And Development Limited Partnership Self-aligning peptides modeled on human elastin and other fibrous proteins
US6083522A (en) 1997-01-09 2000-07-04 Neucoll, Inc. Devices for tissue repair and methods for preparation and use thereof
US6224893B1 (en) 1997-04-11 2001-05-01 Massachusetts Institute Of Technology Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering
US6187555B1 (en) 1998-04-16 2001-02-13 3M Innovative Properties Company Spores with increased sensitivity to sterilants using additives that bind to sterilant-sensitive sites
KR100661413B1 (ko) 1998-07-06 2006-12-27 나노박 오와이 나노박테리아 박멸 방법
US6046160A (en) 1999-07-22 2000-04-04 Deroyal Industries, Inc. Composition and method for enhancing wound healing
EP1282437B1 (en) 2000-05-16 2008-03-19 Genentech, Inc. Treatment of cartilage disorders
HRP20030648B1 (en) 2001-01-25 2011-10-31 Nycomed Pharma As Carrier with solid fibrinogen and solid thrombin
US7449180B2 (en) 2001-02-06 2008-11-11 John Kisiday Macroscopic scaffold containing amphiphilic peptides encapsulating cells
WO2002062961A2 (en) 2001-02-06 2002-08-15 Massachusetts Institute Of Technology Peptide scaffold encapsulation of tissue cells and uses thereof
WO2003084980A2 (en) 2002-04-02 2003-10-16 Northwestern University Peptide amphiphile solutions and self assembled peptide nanofiber networks
WO2003096972A2 (en) * 2002-05-13 2003-11-27 Massachusetts Institute Of Technology Angiogenesis and cardiac tissue engineering with peptide hydrogels and related compositions and methods of use thereof
GB0216286D0 (en) 2002-07-15 2002-08-21 Univ Leeds Network
JP2005534697A (ja) 2002-08-06 2005-11-17 エピックス ファーマシューティカルズ, インコーポレイテッド ペプチド凝集体
US7713923B2 (en) 2003-06-25 2010-05-11 Massachusetts Institute Of Technology Self-assembling peptides incorporating modifications and methods of use thereof
EP1636250B1 (en) 2003-06-25 2016-01-06 Massachusetts Institute Of Technology Self-assembling peptides incorporating modifications and uses thereof
US7846891B2 (en) 2003-10-17 2010-12-07 Massachusetts Institute Of Technology Self-assembling peptides for regeneration and repair of neural tissue
GB0404374D0 (en) 2004-02-27 2004-03-31 Univ Manchester Treatment of bacterial infections
EP4049671A1 (en) 2004-07-06 2022-08-31 3D Matrix, Inc. Purified amphiphilic peptide compositions and uses thereof
CA2592292A1 (en) 2005-01-04 2006-07-13 The Brigham And Women's Hospital, Inc. Sustained delivery of pdgf using self-assembling peptide nanofibers
US9162005B2 (en) 2005-04-25 2015-10-20 Arch Biosurgery, Inc. Compositions for prevention of adhesions and other barrier applications
AU2006241123B2 (en) 2005-04-25 2013-10-03 Massachusetts Institute Of Technology Compositions and methods for promoting hemostasis and other physiological activities
US20060293243A1 (en) 2005-06-17 2006-12-28 Navneet Puri Stable, buffered, pharmaceutical compositions including motilin-like peptides
CA2618184A1 (en) 2005-06-17 2006-12-28 Baxter International Inc. Stable buffered, pharmaceutical compositions including motilin-like peptides
JP4982841B2 (ja) 2005-10-12 2012-07-25 国立大学法人名古屋大学 再生医療骨組成物
HUE037994T2 (hu) * 2006-04-25 2018-09-28 Massachusetts Inst Technology Készítmények és eljárások szennyezõ anyagok, testfolyadékok vagy más anyagok mozgásának befolyásolására és/vagy más fiziológiai állapotok befolyásolására
WO2008039483A2 (en) 2006-09-26 2008-04-03 Massachusetts Institute Of Technology Modified self-assembling peptides
WO2008073392A2 (en) 2006-12-11 2008-06-19 3D Matrix, Inc. Compositions and methods for cardiac tissue protection and regeneration
US9415084B2 (en) 2007-03-14 2016-08-16 Arch Biosurgery, Inc. Treatment of leaky or damaged tight junctions and enhancing extracellular matrix
JP5497451B2 (ja) 2007-12-05 2014-05-21 株式会社スリー・ディー・マトリックス 創傷治癒・皮膚再建材
BRPI0920030B1 (pt) 2008-10-06 2019-03-26 3-D Matrix, Ltd. Agente de oclusão do tecido, agentes hemostáticos, preventivos e de oclusão ou escleroterapia relacionados, e infusão do tecido mucosal
CN101514225B (zh) 2008-10-13 2011-09-14 西安蓝晶生物科技有限公司 自聚体多肽及其制备方法和应用
US9439941B2 (en) 2009-12-14 2016-09-13 The University Of Hong Kong Nano cancer barrier device (NCBD) to immobilize and inhibit the division of metastic cancer stem cells
ES2653667T3 (es) 2011-09-02 2018-02-08 3-D Matrix, Ltd. Péptidos anfifílicos para la oclusión del escape de aire torácico
US20150105336A1 (en) 2012-03-09 2015-04-16 3-D Matrix, Ltd. Mucosa-elevating agent
EP2869903B1 (en) 2012-07-06 2018-11-28 3-D Matrix Ltd. Fill-finish process for peptide solutions
US20160287744A1 (en) 2012-11-14 2016-10-06 3-D Matrix Ltd. Vascular embolic system
CN103251690B (zh) 2013-02-26 2015-10-28 中国人民解放军新疆军区联勤部药品仪器检验所 维药瘤果黑种草子挥发油在制备治疗慢性阻塞性肺病药物的应用
CA2900621A1 (en) 2013-03-06 2014-09-12 3D-Matrix Ltd. Surgical methods employing purified amphiphilic peptide compositions
EP2968693B1 (en) 2013-03-14 2022-06-01 3-D Matrix, Ltd. Materials for gastrointestinal obstruction prevention
EP2968654A1 (en) 2013-03-14 2016-01-20 3-D Matrix, Ltd Treatment for bile leakage
AU2014308597B2 (en) 2013-08-22 2017-01-19 Arch Biosurgery, Inc. Implantable meshes for controlling the movement of fluids
AU2014312881B2 (en) 2013-09-02 2019-05-09 3-D Matrix, Ltd. Syringe and syringe set
CN106459154A (zh) 2014-03-10 2017-02-22 三维矩阵有限责任公司 自组装肽组合物
CN106456811B (zh) 2014-03-10 2021-04-02 三维矩阵有限责任公司 肽组合物的灭菌和过滤
WO2015138473A1 (en) 2014-03-10 2015-09-17 3-D Matrix, Ltd. Autoassembling peptides for the treatment of pulmonary leakage
ES2706492T3 (es) 2014-03-10 2019-03-29 3 D Matrix Ltd Péptidos de autoensamblaje como agentes para la obstrucción bronquial
EP3116524B1 (en) 2014-03-10 2018-11-28 3-D Matrix Ltd. Autoassembling peptides for the treatment of pulmonary bulla
CA2952777A1 (en) 2014-06-20 2015-12-23 3-D Matrix, Ltd. Materials and methods for filling bone voids
WO2017120092A1 (en) 2016-01-06 2017-07-13 3-D Matrix, Ltd. Combination compositions

Also Published As

Publication number Publication date
JP2017513928A (ja) 2017-06-01
US20170072008A1 (en) 2017-03-16
EP3116524A1 (en) 2017-01-18
EP3116524B1 (en) 2018-11-28
US10245299B2 (en) 2019-04-02
WO2015138478A1 (en) 2015-09-17
JP6545727B2 (ja) 2019-07-17

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