ES2712608T3 - Péptidos autoensamblantes para el tratamiento de las bullas pulmonares - Google Patents

Péptidos autoensamblantes para el tratamiento de las bullas pulmonares Download PDF

Info

Publication number
ES2712608T3
ES2712608T3 ES15712233T ES15712233T ES2712608T3 ES 2712608 T3 ES2712608 T3 ES 2712608T3 ES 15712233 T ES15712233 T ES 15712233T ES 15712233 T ES15712233 T ES 15712233T ES 2712608 T3 ES2712608 T3 ES 2712608T3
Authority
ES
Spain
Prior art keywords
solution
self
peptide
assembling peptide
target area
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES15712233T
Other languages
English (en)
Spanish (es)
Inventor
Manav Mehta
Hisashi Tsukada
Eun Gil
Karl Gilbert
Satoru Kobayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3D Matrix Ltd
Original Assignee
3D Matrix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3D Matrix Ltd filed Critical 3D Matrix Ltd
Application granted granted Critical
Publication of ES2712608T3 publication Critical patent/ES2712608T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/34—Trocars; Puncturing needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/04—Tracheal tubes
    • A61M16/0463—Tracheal tubes combined with suction tubes, catheters or the like; Outside connections
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
ES15712233T 2014-03-10 2015-03-10 Péptidos autoensamblantes para el tratamiento de las bullas pulmonares Active ES2712608T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461950529P 2014-03-10 2014-03-10
US201461953049P 2014-03-14 2014-03-14
PCT/US2015/019743 WO2015138478A1 (en) 2014-03-10 2015-03-10 Autoassembling peptides for the treatment of pulmonary bulla

Publications (1)

Publication Number Publication Date
ES2712608T3 true ES2712608T3 (es) 2019-05-14

Family

ID=52737415

Family Applications (1)

Application Number Title Priority Date Filing Date
ES15712233T Active ES2712608T3 (es) 2014-03-10 2015-03-10 Péptidos autoensamblantes para el tratamiento de las bullas pulmonares

Country Status (5)

Country Link
US (1) US10245299B2 (enExample)
EP (1) EP3116524B1 (enExample)
JP (1) JP6545727B2 (enExample)
ES (1) ES2712608T3 (enExample)
WO (1) WO2015138478A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105435211A (zh) 2008-10-06 2016-03-30 三维肽胶株式会社 组织闭塞剂
EP2869903B1 (en) 2012-07-06 2018-11-28 3-D Matrix Ltd. Fill-finish process for peptide solutions
US20160287744A1 (en) 2012-11-14 2016-10-06 3-D Matrix Ltd. Vascular embolic system
DK3116896T3 (en) 2014-03-10 2019-03-18 3 D Matrix Ltd SELF-PREPARING PEPTIME COMPOSITIONS
ES2712608T3 (es) 2014-03-10 2019-05-14 3 D Matrix Ltd Péptidos autoensamblantes para el tratamiento de las bullas pulmonares
ES3037364T3 (en) 2014-03-10 2025-10-01 3 D Matrix Ltd Sterilization and filtration of peptide compositions
WO2015138475A1 (en) * 2014-03-10 2015-09-17 3-D Matrix, Ltd. Self-assembling peptides as bronchial obstruction agents
WO2017120092A1 (en) * 2016-01-06 2017-07-13 3-D Matrix, Ltd. Combination compositions
CN106539561B (zh) * 2016-12-09 2023-08-11 中国科学院西安光学精密机械研究所 一种肺大泡破裂部位定位装置
CN117085140A (zh) 2017-12-15 2023-11-21 立美基股份有限公司 表面活性剂肽纳米结构及在药物递送中的用途
CN112368295B (zh) 2018-07-03 2025-03-21 立美基股份有限公司 离子性自组装肽
CN115397454A (zh) 2020-03-31 2022-11-25 立美基股份有限公司 通过辐照对自组装肽进行灭菌
US20240366717A1 (en) * 2020-08-10 2024-11-07 Gel4Med, Inc. Antimicrobial matrix formed from peptide hydrogels
WO2022035783A2 (en) * 2020-08-10 2022-02-17 Gel4Med, Inc. Topical and parenteral use and administration of self-assembling amphiphilic peptide hydrogels

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582640A (en) 1982-03-08 1986-04-15 Collagen Corporation Injectable cross-linked collagen implant material
US4466641A (en) 1982-08-04 1984-08-21 The Lockformer Company Duct connecting system
US4642117A (en) 1985-03-22 1987-02-10 Collagen Corporation Mechanically sheared collagen implant material and method
US4947840A (en) 1987-08-21 1990-08-14 Massachusetts Institute Of Technology Biodegradable templates for the regeneration of tissues
US5236903A (en) 1988-06-24 1993-08-17 Ichiro Azuma Polypeptide comprising repeated cell-adhesive core sequences
US5110604A (en) 1988-06-30 1992-05-05 Collagen Corporation Processes for producing collagen matrixes and methods of using same
US5126141A (en) 1988-11-16 1992-06-30 Mediventures Incorporated Composition and method for post-surgical adhesion reduction with thermo-irreversible gels of polyoxyalkylene polymers and ionic polysaccharides
US5550187A (en) 1988-11-21 1996-08-27 Collagen Corporation Method of preparing crosslinked biomaterial compositions for use in tissue augmentation
US5629291A (en) 1992-01-31 1997-05-13 La Jolla Cancer Research Foundation Methods of modulating fibronectin extracellular matrix assembly
US5292514A (en) 1992-06-24 1994-03-08 Minnesota Mining And Manufacturing Company Azlactone-functional substrates, corneal prostheses, and manufacture and use thereof
US5955343A (en) 1992-12-28 1999-09-21 Massachusetts Institute Of Technology Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor
US5670483A (en) 1992-12-28 1997-09-23 Massachusetts Insititute Of Technology Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor
GB2274988A (en) 1993-02-10 1994-08-17 Mcconn Stern Rita Iodine containing wound-healing preparations
US5709854A (en) 1993-04-30 1998-01-20 Massachusetts Institute Of Technology Tissue formation by injecting a cell-polymeric solution that gels in vivo
US5773577A (en) 1994-03-03 1998-06-30 Protein Polymer Technologies Products comprising substrates capable of enzymatic cross-linking
US5527610A (en) 1994-05-20 1996-06-18 The Uab Research Foundation Elastomeric polypeptide matrices for preventing adhesion of biological materials
US5510102A (en) 1995-01-23 1996-04-23 The Regents Of The University Of California Plasma and polymer containing surgical hemostatic adhesives
WO1996040033A1 (en) 1995-06-07 1996-12-19 Clarion Pharmaceuticals Inc. Non-biological patch for hemostasis
HUP9903586A3 (en) 1996-04-04 2003-02-28 Baxter Ag Hemostatic sponge based on collagen
US6489446B1 (en) 1996-08-07 2002-12-03 Hsc Research And Development Limited Partnership Self-aligning peptides modeled on human elastin and other fibrous proteins
WO1998030141A2 (en) 1997-01-09 1998-07-16 Cohesion Technologies, Inc. Devices for tissue repair and methods for preparation and use thereof
US6224893B1 (en) 1997-04-11 2001-05-01 Massachusetts Institute Of Technology Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering
US6187555B1 (en) 1998-04-16 2001-02-13 3M Innovative Properties Company Spores with increased sensitivity to sterilants using additives that bind to sterilant-sensitive sites
ATE282959T1 (de) 1998-07-06 2004-12-15 Nanobac Oy Verfahren zur beseitigung von nanobakterien
US6046160A (en) 1999-07-22 2000-04-04 Deroyal Industries, Inc. Composition and method for enhancing wound healing
AU2001263215A1 (en) 2000-05-16 2001-11-26 Genentech Inc. Method for treating cartilage disorders
PL206194B1 (pl) 2001-01-25 2010-07-30 Nycomed Pharma Asnycomed Pharma As Sposób wytwarzania zawiesiny cząstek fibrynogenu i trombiny, zawiesina zawierająca fibrynogen, trombinę i alkohol oraz sposób powlekania nośnika taką zawiesiną
US7449180B2 (en) 2001-02-06 2008-11-11 John Kisiday Macroscopic scaffold containing amphiphilic peptides encapsulating cells
WO2002062969A2 (en) 2001-02-06 2002-08-15 Massachusetts Institute Of Technology Cellular reprogramming in peptide hydrogel and uses thereof
AU2003222167A1 (en) 2002-04-02 2003-10-20 Northwestern University Peptide amphiphile solutions and self assembled peptide nanofiber networks
US20040242469A1 (en) 2002-05-13 2004-12-02 Lee Richard T. Angiogenesis and cardiac tissue engineering with peptide hydrogels and related compositions and methods of use thereof
GB0216286D0 (en) 2002-07-15 2002-08-21 Univ Leeds Network
JP2005534697A (ja) 2002-08-06 2005-11-17 エピックス ファーマシューティカルズ， インコーポレイテッド ペプチド凝集体
US7713923B2 (en) 2003-06-25 2010-05-11 Massachusetts Institute Of Technology Self-assembling peptides incorporating modifications and methods of use thereof
WO2005014615A2 (en) 2003-06-25 2005-02-17 Massachusetts Institute Of Technology Self-assembling peptides incorporating modifications and methods of use thereof
US7846891B2 (en) 2003-10-17 2010-12-07 Massachusetts Institute Of Technology Self-assembling peptides for regeneration and repair of neural tissue
GB0404374D0 (en) 2004-02-27 2004-03-31 Univ Manchester Treatment of bacterial infections
CA2572964C (en) 2004-07-06 2018-03-06 3D Matrix, Inc. Purified amphiphilic peptide compositions and uses thereof
AU2005323062A1 (en) 2005-01-04 2006-07-13 The Brigham And Women's Hospital, Inc. Sustained delivery of PDGF using self-assembling peptide nanofibers
KR20100102750A (ko) 2005-04-25 2010-09-24 메사추세츠 인스티튜트 오브 테크놀로지 지혈 및 다른 생리학적 활성을 촉진하기 위한 조성물 및 방법
US9162005B2 (en) 2005-04-25 2015-10-20 Arch Biosurgery, Inc. Compositions for prevention of adhesions and other barrier applications
EP1896054A1 (en) 2005-06-17 2008-03-12 Baxter International Inc. Stable buffered, pharmaceutical compositions including motilin-like peptides
US20060293243A1 (en) 2005-06-17 2006-12-28 Navneet Puri Stable, buffered, pharmaceutical compositions including motilin-like peptides
JP4982841B2 (ja) 2005-10-12 2012-07-25 国立大学法人名古屋大学 再生医療骨組成物
HUE037994T2 (hu) 2006-04-25 2018-09-28 Massachusetts Inst Technology Készítmények és eljárások szennyezõ anyagok, testfolyadékok vagy más anyagok mozgásának befolyásolására és/vagy más fiziológiai állapotok befolyásolására
EP2066697A2 (en) 2006-09-26 2009-06-10 Massachusetts Institute of Technology Modified self-assembling peptides
JP5558104B2 (ja) 2006-12-11 2014-07-23 スリー−ディー マトリックス， インコーポレイテッド 心組織の保護および再生のための組成物および方法
US9415084B2 (en) 2007-03-14 2016-08-16 Arch Biosurgery, Inc. Treatment of leaky or damaged tight junctions and enhancing extracellular matrix
ES2534770T3 (es) 2007-12-05 2015-04-28 3-D Matrix, Ltd. Material para la curación de heridas y la reconstrucción de la piel
CN105435211A (zh) * 2008-10-06 2016-03-30 三维肽胶株式会社 组织闭塞剂
CN101514225B (zh) 2008-10-13 2011-09-14 西安蓝晶生物科技有限公司 自聚体多肽及其制备方法和应用
WO2011072482A1 (en) 2009-12-14 2011-06-23 The University Of Hong Kong Nano cancer barrier device(ncbd) to immobilize and inhibit the division of metastic cancer stem cells
JP6034868B2 (ja) * 2011-09-02 2016-11-30 株式会社スリー・ディー・マトリックス 胸部の空気漏れ閉塞のための両親媒性ペプチド
US20150105336A1 (en) 2012-03-09 2015-04-16 3-D Matrix, Ltd. Mucosa-elevating agent
EP2869903B1 (en) 2012-07-06 2018-11-28 3-D Matrix Ltd. Fill-finish process for peptide solutions
US20160287744A1 (en) 2012-11-14 2016-10-06 3-D Matrix Ltd. Vascular embolic system
CN103251690B (zh) 2013-02-26 2015-10-28 中国人民解放军新疆军区联勤部药品仪器检验所 维药瘤果黑种草子挥发油在制备治疗慢性阻塞性肺病药物的应用
HK1220116A1 (zh) 2013-03-06 2017-04-28 3-D Matrix Ltd. 使用纯化的两亲性多肽组合物的外科手术方法
CA2905182A1 (en) 2013-03-14 2014-09-18 3-D Matrix, Ltd. Materials for gastrointestinal obstruction prevention
WO2014141160A1 (en) 2013-03-14 2014-09-18 3-D Matrix, Ltd Treatment for bile leakage
WO2015027203A1 (en) 2013-08-22 2015-02-26 Arch Biosurgery, Inc. Implantable meshes for controlling the movement of fluids
AU2014312881B2 (en) 2013-09-02 2019-05-09 3-D Matrix, Ltd. Syringe and syringe set
ES2712608T3 (es) 2014-03-10 2019-05-14 3 D Matrix Ltd Péptidos autoensamblantes para el tratamiento de las bullas pulmonares
ES3037364T3 (en) 2014-03-10 2025-10-01 3 D Matrix Ltd Sterilization and filtration of peptide compositions
DK3116896T3 (en) 2014-03-10 2019-03-18 3 D Matrix Ltd SELF-PREPARING PEPTIME COMPOSITIONS
JP2017513927A (ja) 2014-03-10 2017-06-01 株式会社スリー・ディー・マトリックス 肺の漏出を治療するための自発組織化ペプチド
WO2015138475A1 (en) 2014-03-10 2015-09-17 3-D Matrix, Ltd. Self-assembling peptides as bronchial obstruction agents
JP2017519568A (ja) 2014-06-20 2017-07-20 株式会社スリー・ディー・マトリックス 骨間隙を充填するための材料および方法
WO2017120092A1 (en) 2016-01-06 2017-07-13 3-D Matrix, Ltd. Combination compositions

Also Published As

Publication number Publication date
WO2015138478A1 (en) 2015-09-17
JP6545727B2 (ja) 2019-07-17
EP3116524A1 (en) 2017-01-18
US20170072008A1 (en) 2017-03-16
US10245299B2 (en) 2019-04-02
JP2017513928A (ja) 2017-06-01
EP3116524B1 (en) 2018-11-28

Similar Documents

Publication Publication Date Title
ES2706492T3 (es) Péptidos de autoensamblaje como agentes para la obstrucción bronquial
ES2729214T3 (es) Péptidos de autoensamblaje para el tratamiento de la fuga pulmonar
US10245299B2 (en) Autoassembling peptides for the treatment of pulmonary bulla
US20160030628A1 (en) Treatment for bile leakage
ES2393939T3 (es) Kits, formulaciones y soluciones que tienen cantidades de agentes de visualización enzimaticamente permisivos y usos de las mismas
ES2907125T3 (es) Preparación de HGF adecuada para el tratamiento de trastornos neurológicos
JP2018115208A (ja) 消化管閉塞の予防のための材料
US20150105336A1 (en) Mucosa-elevating agent
KR20230042597A (ko) 자기 조립 양친매성 펩티드 하이드로겔
JP2017519568A (ja) 骨間隙を充填するための材料および方法
ES2822923T3 (es) Péptidos auto-ensamblables que comprenden aminoácidos polares no iónicos
US20200078489A1 (en) Pancreatic fistula occlusion
JP2019518569A (ja) 内視鏡的剥離術後の食道狭窄を予防するための自己集合性ペプチドマトリックス
EP3429653B1 (en) Preventing biological tissue adhesion
US20210023257A1 (en) Cerebrospinal fluid leakage occlusion
EP3389734B1 (en) Self-assembling peptides comprising non-ionic polar amino acids for anti-adhesion
EP4192492A2 (en) Topical and parenteral use and administration of self-assembling amphiphilic peptide hydrogels
US20240293164A1 (en) Methods and compositions of cryoablation with drug delivery