ES2703052T3 - Aislamiento de mutantes potenciadores del tráfico de proteína de entrega de fármacos - Google Patents
Aislamiento de mutantes potenciadores del tráfico de proteína de entrega de fármacos Download PDFInfo
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- ES2703052T3 ES2703052T3 ES13826083T ES13826083T ES2703052T3 ES 2703052 T3 ES2703052 T3 ES 2703052T3 ES 13826083 T ES13826083 T ES 13826083T ES 13826083 T ES13826083 T ES 13826083T ES 2703052 T3 ES2703052 T3 ES 2703052T3
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
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- Chemical & Material Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
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- Biochemistry (AREA)
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- Crystallography & Structural Chemistry (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Computational Biology (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US201261679306P | 2012-08-03 | 2012-08-03 | |
| PCT/US2013/053493 WO2014022811A1 (en) | 2012-08-03 | 2013-08-02 | Isolating traffic-enhancing mutants of drug delivery protein |
Publications (1)
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| ES2703052T3 true ES2703052T3 (es) | 2019-03-06 |
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| ES13826083T Active ES2703052T3 (es) | 2012-08-03 | 2013-08-02 | Aislamiento de mutantes potenciadores del tráfico de proteína de entrega de fármacos |
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| JP (2) | JP6618360B2 (enExample) |
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| AU (2) | AU2013296218B2 (enExample) |
| BR (1) | BR112015002004A2 (enExample) |
| CA (1) | CA2881582A1 (enExample) |
| DK (1) | DK2880160T3 (enExample) |
| ES (1) | ES2703052T3 (enExample) |
| IL (1) | IL236955A0 (enExample) |
| IN (1) | IN2015DN01196A (enExample) |
| MX (1) | MX366347B (enExample) |
| PL (1) | PL2880160T3 (enExample) |
| PT (1) | PT2880160T (enExample) |
| RU (1) | RU2015105052A (enExample) |
| WO (1) | WO2014022811A1 (enExample) |
| ZA (1) | ZA201500739B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US9078927B2 (en) | 2007-07-06 | 2015-07-14 | Cedars-Sinai Medical Center | Self-assembling complex for targeting chemical agents to cells |
| WO2010085665A2 (en) | 2009-01-23 | 2010-07-29 | Cedars-Sinai Medical Center | Targeted delivery system |
| KR102115630B1 (ko) * | 2012-08-03 | 2020-05-27 | 세다르스-신나이 메디칼 센터 | 약물 전달 단백질의 수송-증진 돌연변이체의 단리 |
| JP6640715B2 (ja) | 2013-05-08 | 2020-02-05 | セダーズ−シナイ メディカル センター | 腫瘍毒性に対する標的コロールおよびｍｒｉ |
| CN106413738B (zh) | 2014-01-17 | 2020-12-29 | 席德-西奈医疗中心 | 受体靶向构造物和其使用 |
| CN106170305A (zh) | 2014-04-04 | 2016-11-30 | 席德-西奈医疗中心 | 用her3靶向纳米粒子靶向曲妥珠单抗抗性her2+乳腺癌 |
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| US5439829A (en) | 1991-01-30 | 1995-08-08 | Eli Lilly And Company | Immobilization of biologically active molecules by changing the Oxidation state of a chelated transition metal ion |
| US6287792B1 (en) | 1991-06-17 | 2001-09-11 | The Regents Of The University Of California | Drug delivery of antisense oligonucleotides and peptides to tissues in vivo and to cells using avidin-biotin technology |
| GB9223084D0 (en) | 1992-11-04 | 1992-12-16 | Imp Cancer Res Tech | Compounds to target cells |
| FI943242L (fi) | 1993-07-15 | 1995-01-16 | Jcr Pharmaceutical Co Ltd | Lääke munuais- ja maksatauteihin |
| US6465253B1 (en) * | 1994-09-08 | 2002-10-15 | Genvec, Inc. | Vectors and methods for gene transfer to cells |
| US5559099A (en) * | 1994-09-08 | 1996-09-24 | Genvec, Inc. | Penton base protein and methods of using same |
| US6066322A (en) | 1995-03-03 | 2000-05-23 | Millennium Pharmaceuticals, Inc. | Methods for the treatment of immune disorders |
| NZ323834A (en) | 1995-11-28 | 2000-01-28 | Genvec Inc | Chimeric adenovirus coat protein vectors and methods for gene transfer to cells |
| WO1998035036A1 (en) | 1997-02-10 | 1998-08-13 | Genentech, Inc. | Heregulin variants |
| GB9709421D0 (en) | 1997-05-10 | 1997-07-02 | Zeneca Ltd | Chemical compounds |
| HRP20010119B1 (hr) | 1998-08-18 | 2008-05-31 | The Regents Of The University Of California | Sprječavanje stvaranja sluzi u dišnim putevima primjenom antagonista egf-r |
| US6333396B1 (en) | 1998-10-20 | 2001-12-25 | Enzon, Inc. | Method for targeted delivery of nucleic acids |
| CA2391534A1 (en) | 1999-11-15 | 2001-05-25 | Drug Innovation & Design, Inc. | Selective cellular targeting: multifunctional delivery vehicles |
| US20010055783A1 (en) | 2000-06-16 | 2001-12-27 | Allnutt F.C. Thomas | Recombinant phycobiliprotein and phycobiliprotein linker fusion proteins and uses therefore |
| IT1318704B1 (it) | 2000-09-22 | 2003-08-27 | Consorzio Interuniversitario P | Vettori chimerici e loro uso per il trasferimento di geni eterologhi. |
| WO2002062823A2 (en) | 2001-02-02 | 2002-08-15 | Yale University | Peptides for facilitating composite receptor expression and translocation of macromolecules |
| EP1266963A1 (en) * | 2001-06-15 | 2002-12-18 | Crucell Holland B.V. | Chimaeric phages |
| SE0201863D0 (en) | 2002-06-18 | 2002-06-18 | Cepep Ab | Cell penetrating peptides |
| US7329638B2 (en) | 2003-04-30 | 2008-02-12 | The Regents Of The University Of Michigan | Drug delivery compositions |
| US7205387B2 (en) | 2003-08-28 | 2007-04-17 | Agency For Science, Technology And Research | Recombinant polypeptide useful for neurotrophin receptor mediated gene delivery and as neurotrophin agonist |
| WO2005117928A1 (en) | 2004-05-30 | 2005-12-15 | Cemines, Inc. | Compositions and methods for the treatment of skin cancer |
| US8057821B2 (en) | 2004-11-03 | 2011-11-15 | Egen, Inc. | Biodegradable cross-linked cationic multi-block copolymers for gene delivery and methods of making thereof |
| US20110052697A1 (en) | 2006-05-17 | 2011-03-03 | Gwangju Institute Of Science & Technology | Aptamer-Directed Drug Delivery |
| JP4479755B2 (ja) | 2007-07-03 | 2010-06-09 | ソニー株式会社 | 有機エレクトロルミネッセンス素子、及び、有機エレクトロルミネッセンス表示装置 |
| US9078927B2 (en) | 2007-07-06 | 2015-07-14 | Cedars-Sinai Medical Center | Self-assembling complex for targeting chemical agents to cells |
| EP2220241B1 (en) * | 2007-11-28 | 2016-09-14 | The Trustees Of The University Of Pennsylvania | Adenovirus comprising a Simian E Adenovirus SAdV-39 capsid hexon protein and uses thereof |
| WO2010085665A2 (en) | 2009-01-23 | 2010-07-29 | Cedars-Sinai Medical Center | Targeted delivery system |
| US9580476B2 (en) | 2011-10-05 | 2017-02-28 | Genvec, Inc. | Adenoviral vector-based respiratory syncytial virus (RSV) vaccine |
| KR102115630B1 (ko) * | 2012-08-03 | 2020-05-27 | 세다르스-신나이 메디칼 센터 | 약물 전달 단백질의 수송-증진 돌연변이체의 단리 |
| JP6640715B2 (ja) | 2013-05-08 | 2020-02-05 | セダーズ−シナイ メディカル センター | 腫瘍毒性に対する標的コロールおよびｍｒｉ |
| CN106413738B (zh) | 2014-01-17 | 2020-12-29 | 席德-西奈医疗中心 | 受体靶向构造物和其使用 |
| CN106170305A (zh) | 2014-04-04 | 2016-11-30 | 席德-西奈医疗中心 | 用her3靶向纳米粒子靶向曲妥珠单抗抗性her2+乳腺癌 |
| AU2017271662A1 (en) * | 2016-05-27 | 2018-12-06 | Cedars-Sinai Medical Center | Drug-delivery nanoparticles and treatments for drug-resistant cancer |
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| PL2880160T3 (pl) | 2019-03-29 |
| BR112015002004A2 (pt) | 2017-07-04 |
| KR20150038543A (ko) | 2015-04-08 |
| EP2880160A4 (en) | 2016-04-20 |
| IL236955A0 (en) | 2015-03-31 |
| AU2013296218A1 (en) | 2015-02-19 |
| US10036009B2 (en) | 2018-07-31 |
| PT2880160T (pt) | 2018-12-17 |
| WO2014022811A1 (en) | 2014-02-06 |
| JP6618360B2 (ja) | 2019-12-11 |
| EP2880160B1 (en) | 2018-09-19 |
| KR102115630B1 (ko) | 2020-05-27 |
| CN104619839A (zh) | 2015-05-13 |
| ZA201500739B (en) | 2018-07-25 |
| US20180298376A1 (en) | 2018-10-18 |
| US10752893B2 (en) | 2020-08-25 |
| RU2015105052A (ru) | 2016-09-27 |
| AU2013296218B2 (en) | 2019-07-18 |
| JP2020002138A (ja) | 2020-01-09 |
| EP2880160A1 (en) | 2015-06-10 |
| MX366347B (es) | 2019-07-05 |
| DK2880160T3 (en) | 2019-01-14 |
| CA2881582A1 (en) | 2014-02-06 |
| IN2015DN01196A (enExample) | 2015-06-26 |
| MX2015001366A (es) | 2015-08-13 |
| AU2019204815A1 (en) | 2019-07-25 |
| JP2015527343A (ja) | 2015-09-17 |
| US20150240231A1 (en) | 2015-08-27 |
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