ES2674119T3 - Método para producir un tubo para su uso en la formación de un stent - Google Patents
Método para producir un tubo para su uso en la formación de un stent Download PDFInfo
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- ES2674119T3 ES2674119T3 ES13771185.9T ES13771185T ES2674119T3 ES 2674119 T3 ES2674119 T3 ES 2674119T3 ES 13771185 T ES13771185 T ES 13771185T ES 2674119 T3 ES2674119 T3 ES 2674119T3
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
- B29C48/03—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor characterised by the shape of the extruded material at extrusion
- B29C48/09—Articles with cross-sections having partially or fully enclosed cavities, e.g. pipes or channels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
- B29C48/15—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor incorporating preformed parts or layers, e.g. extrusion moulding around inserts
- B29C48/151—Coating hollow articles
- B29C48/152—Coating hollow articles the inner surfaces thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C55/00—Shaping by stretching, e.g. drawing through a die; Apparatus therefor
- B29C55/22—Shaping by stretching, e.g. drawing through a die; Apparatus therefor of tubes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C55/00—Shaping by stretching, e.g. drawing through a die; Apparatus therefor
- B29C55/22—Shaping by stretching, e.g. drawing through a die; Apparatus therefor of tubes
- B29C55/26—Shaping by stretching, e.g. drawing through a die; Apparatus therefor of tubes biaxial
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C55/00—Shaping by stretching, e.g. drawing through a die; Apparatus therefor
- B29C55/30—Drawing through a die
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C55/00—Shaping by stretching, e.g. drawing through a die; Apparatus therefor
- B29C55/22—Shaping by stretching, e.g. drawing through a die; Apparatus therefor of tubes
- B29C55/24—Shaping by stretching, e.g. drawing through a die; Apparatus therefor of tubes radial
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C70/00—Shaping composites, i.e. plastics material comprising reinforcements, fillers or preformed parts, e.g. inserts
- B29C70/04—Shaping composites, i.e. plastics material comprising reinforcements, fillers or preformed parts, e.g. inserts comprising reinforcements only, e.g. self-reinforcing plastics
- B29C70/28—Shaping operations therefor
- B29C70/40—Shaping or impregnating by compression not applied
- B29C70/50—Shaping or impregnating by compression not applied for producing articles of indefinite length, e.g. prepregs, sheet moulding compounds [SMC] or cross moulding compounds [XMC]
- B29C70/52—Pultrusion, i.e. forming and compressing by continuously pulling through a die
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
- B29D23/00—Producing tubular articles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2995/00—Properties of moulding materials, reinforcements, fillers, preformed parts or moulds
- B29K2995/0037—Other properties
- B29K2995/0059—Degradable
- B29K2995/006—Bio-degradable, e.g. bioabsorbable, bioresorbable or bioerodible
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2023/00—Tubular articles
- B29L2023/005—Hoses, i.e. flexible
- B29L2023/007—Medical tubes other than catheters
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Mechanical Engineering (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Transplantation (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Materials For Medical Uses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261704795P | 2012-09-24 | 2012-09-24 | |
| US201261704795P | 2012-09-24 | ||
| GB1217018.9A GB2512016A (en) | 2012-09-24 | 2012-09-24 | Methods |
| GB201217018 | 2012-09-24 | ||
| PCT/GB2013/052499 WO2014045068A1 (en) | 2012-09-24 | 2013-09-24 | Method of producing a tube for use in the formation of a stent, and such tube |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2674119T3 true ES2674119T3 (es) | 2018-06-27 |
Family
ID=47190502
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES18158541T Active ES2788392T3 (es) | 2012-09-24 | 2013-09-24 | Un tubo para su utilización en un stent |
| ES13771185.9T Active ES2674119T3 (es) | 2012-09-24 | 2013-09-24 | Método para producir un tubo para su uso en la formación de un stent |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
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Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8814930B2 (en) | 2007-01-19 | 2014-08-26 | Elixir Medical Corporation | Biodegradable endoprosthesis and methods for their fabrication |
| US10779855B2 (en) | 2011-08-05 | 2020-09-22 | Route 92 Medical, Inc. | Methods and systems for treatment of acute ischemic stroke |
| KR101489263B1 (ko) | 2014-02-26 | 2015-02-04 | 썬텍 주식회사 | 고분자 스텐트의 제조방법 및 폴리락트산 고분자 스텐트 |
| US10010436B2 (en) | 2012-09-20 | 2018-07-03 | Dotter Intellectual Pte, Ltd. | Polymeric stent and methods of manufacturing the same |
| US9265512B2 (en) | 2013-12-23 | 2016-02-23 | Silk Road Medical, Inc. | Transcarotid neurovascular catheter |
| US9750622B2 (en) | 2014-06-17 | 2017-09-05 | Abbott Cardiovascular Systems Inc. | High molecular weight polylactide and polycaprolactone copolymer and blends for bioresorbable vascular scaffolds |
| US10022906B2 (en) * | 2014-07-30 | 2018-07-17 | Abbott Cardiovascular Systems Inc. | Methods for solid phase processing of tubes and medical devices made from the processed tubes |
| US9730819B2 (en) | 2014-08-15 | 2017-08-15 | Elixir Medical Corporation | Biodegradable endoprostheses and methods of their fabrication |
| US9855156B2 (en) | 2014-08-15 | 2018-01-02 | Elixir Medical Corporation | Biodegradable endoprostheses and methods of their fabrication |
| US20160175084A1 (en) * | 2014-12-19 | 2016-06-23 | Volcano Corporation | Biodegradable filter and support frame |
| US10799669B2 (en) | 2017-01-20 | 2020-10-13 | Route 92 Medical, Inc. | Single operator intracranial medical device delivery systems and methods of use |
| US10099431B2 (en) * | 2015-08-21 | 2018-10-16 | Abbott Cardiovascular Systems Inc. | Method to increase radial strength of a bioresorbable scaffold |
| US11622872B2 (en) | 2016-05-16 | 2023-04-11 | Elixir Medical Corporation | Uncaging stent |
| EP3861961B1 (en) | 2016-05-16 | 2025-11-12 | Elixir Medical Corporation | Uncaging stent |
| EP3463128B1 (en) * | 2016-06-03 | 2021-11-10 | Q3 Medical Devices Limited | Stent |
| CN106729952B (zh) * | 2016-12-23 | 2020-05-22 | 西安交通大学 | Ppf/ppf-da光固化材料骨胶带 |
| CN108272481A (zh) * | 2016-12-30 | 2018-07-13 | 香港科技大学深圳研究院 | 一种自适应支架及其制造方法 |
| CN114984407B (zh) | 2017-01-10 | 2025-05-23 | 92号医疗公司 | 在颅内血管中执行医疗手术的系统、导管和导管前进装置 |
| CN106891558A (zh) * | 2017-02-27 | 2017-06-27 | 柳州市人民医院 | 抽血保护装置的生产方法 |
| EP3381501B1 (en) * | 2017-03-30 | 2024-05-29 | PFM Medical AG | Implantable access device for accessing the vascular system of a human or animal body |
| ES2935295T3 (es) * | 2017-05-25 | 2023-03-03 | Tepha Inc | Formación continua de tubos de poli-4-hidroxibutirato y sus copolímeros |
| CN107350305B (zh) * | 2017-07-03 | 2019-04-02 | 中北大学 | 一种高性能镁合金薄壁管的挤压拉伸成形方法 |
| CN114870097B (zh) * | 2017-09-08 | 2024-04-09 | 宙斯有限公司 | 具有控制的取向的聚合物管 |
| RU177450U1 (ru) * | 2017-11-07 | 2018-02-21 | Антон Михайлович Чернышев | Устройство для изготовления теплоизолированных труб |
| EP4527441A3 (en) | 2018-05-17 | 2025-06-18 | Route 92 Medical, Inc. | Aspiration catheter systems and methods of use |
| CN110962340A (zh) * | 2019-12-18 | 2020-04-07 | 北京工业大学 | 一种光固化3d打印编织网状海藻酸钠水凝胶血管支架的制备方法 |
| US20220111177A1 (en) | 2020-10-09 | 2022-04-14 | Route 92 Medical, Inc. | Aspiration catheter systems and methods of use |
| GB202020346D0 (en) * | 2020-12-22 | 2021-02-03 | Imperial College Innovations Ltd | A device and a method |
| CN113413491B (zh) * | 2021-04-30 | 2022-11-04 | 中国科学院大学温州研究院(温州生物材料与工程研究所) | 基于PTMC-b-PEG-b-PTMC共聚物的生物柔性弹性体肠吻合支架及制备方法 |
| CN113288505B (zh) | 2021-04-30 | 2023-02-03 | 中国科学院大学温州研究院(温州生物材料与工程研究所) | 基于ptmc的生物可吸收柔性弹性体的肠吻合支架及其制备方法 |
| US20230372574A1 (en) * | 2022-05-23 | 2023-11-23 | Northwestern University | In vivo detection of surgical materials |
| CN114953544B (zh) * | 2022-05-26 | 2024-03-08 | 山东中鲁管业有限公司 | 一种耐磨损的高分子管材生产工艺及装置 |
| CN114851528B (zh) * | 2022-07-06 | 2022-09-23 | 北京蓝晶微生物科技有限公司 | 一种聚羟基烷酸酯成型体及其制备方法 |
| CN115609880B (zh) * | 2022-09-23 | 2025-11-25 | 南海海缆有限公司 | 模具及生产设备 |
Family Cites Families (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2561569A (en) * | 1947-01-10 | 1951-07-24 | Wardlyn Corp | Method of making catheters |
| US3201827A (en) * | 1963-04-08 | 1965-08-24 | Anaconda Wire & Cable Co | Tube-stretching mandrel |
| GB1506565A (en) | 1974-03-05 | 1978-04-05 | Nat Res Dev | Production of polyethylene filaments |
| US4528832A (en) * | 1983-01-26 | 1985-07-16 | Fuchs Jr Francis J | Methods and apparatus for increasing the efficiency of tubing extrusion |
| GB8408336D0 (en) | 1984-03-30 | 1984-05-10 | Ward I M | Tubular materials |
| EP0157601B1 (en) | 1984-03-30 | 1991-05-08 | National Research Development Corporation | Tubular materials |
| GB8827967D0 (en) * | 1988-11-30 | 1989-01-05 | Ward I M | Die-free drawing |
| SE468666B (sv) * | 1990-09-27 | 1993-03-01 | Plm Ab | Saett och anordning foer att kristallisera amorft plastmaterial i ett aemne |
| US5401257A (en) * | 1993-04-27 | 1995-03-28 | Boston Scientific Corporation | Ureteral stents, drainage tubes and the like |
| NL9400453A (nl) * | 1994-03-22 | 1995-11-01 | Wavin Bv | Werkwijze en inrichting voor het vervaardigen van biaxiaal georiënteerde buis uit thermoplastisch kunststofmateriaal. |
| NL9400451A (nl) * | 1994-03-22 | 1995-11-01 | Wavin Bv | Werkwijze en inrichting voor het vervaardigen van biaxiaal georiënteerde buis uit thermoplastisch kunststofmateriaal. |
| NL9400738A (nl) * | 1994-05-04 | 1995-12-01 | Wavin Bv | Werkwijze en inrichting voor het vervaardigen van biaxiaal georiënteerde buis uit thermoplastisch kunststofmateriaal. |
| US5609605A (en) * | 1994-08-25 | 1997-03-11 | Ethicon, Inc. | Combination arterial stent |
| NL1001259C2 (nl) * | 1995-05-03 | 1996-11-05 | Wavin Bv | Werkwijze voor het behandelen van een geëxtrudeerd kunststof profiel en extrusie-installatie daarvoor. |
| US5702656A (en) * | 1995-06-07 | 1997-12-30 | United States Surgical Corporation | Process for making polymeric articles |
| GB9522477D0 (en) * | 1995-11-02 | 1996-01-03 | Howmedica | Method of improving the wear quality of ultra-high molecular weight polyethylene |
| JPH09241412A (ja) * | 1996-03-07 | 1997-09-16 | Sumitomo Electric Ind Ltd | 延伸ポリテトラフルオロエチレンチューブとその製造方法 |
| US5928279A (en) | 1996-07-03 | 1999-07-27 | Baxter International Inc. | Stented, radially expandable, tubular PTFE grafts |
| DE19728345A1 (de) * | 1997-07-03 | 1999-01-07 | Asea Brown Boveri | Kraft- und formschlüssige Verbindung von rotierenden Bauteilen |
| US6626939B1 (en) | 1997-12-18 | 2003-09-30 | Boston Scientific Scimed, Inc. | Stent-graft with bioabsorbable structural support |
| JP2000167922A (ja) * | 1998-12-01 | 2000-06-20 | Mitsubishi Chemicals Corp | 樹脂管状体の製造方法及び装置 |
| US6187054B1 (en) * | 1999-02-04 | 2001-02-13 | Endomed Inc. | Method of making large diameter vascular prosteheses and a vascular prosthesis made by said method |
| NL1012032C2 (nl) * | 1999-03-05 | 2000-09-06 | Wavin Bv | Werkwijze voor het vervaardigen van een buis van biaxiaal georiënteerd thermoplastisch kunststofmateriaal. |
| FR2806956B1 (fr) * | 2000-03-29 | 2003-05-09 | Alphacan Sa | Procede et ligne de fabrication en continu de tubes en matiere plastique avec etirage bi-axial, et tube en matiere plastique obtenu |
| CA2436781C (en) * | 2000-11-22 | 2010-11-02 | Impra, Inc. A Subsidiary Of C.R. Bard, Inc. | High density microwall expanded polytetrafluoroethylene tubular structure |
| JP2002249555A (ja) * | 2001-02-23 | 2002-09-06 | Nippon Zeon Co Ltd | 管状成形品 |
| WO2004023985A2 (en) * | 2002-09-13 | 2004-03-25 | Linvatec Corporation | Drawn expanded stent |
| US7025745B2 (en) * | 2002-10-07 | 2006-04-11 | Advanced Cardiovascular Systems, Inc. | Method of making a catheter balloon using a tapered mandrel |
| US7763063B2 (en) | 2003-09-03 | 2010-07-27 | Bolton Medical, Inc. | Self-aligning stent graft delivery system, kit, and method |
| US8292943B2 (en) | 2003-09-03 | 2012-10-23 | Bolton Medical, Inc. | Stent graft with longitudinal support member |
| US20050137678A1 (en) | 2003-12-22 | 2005-06-23 | Medtronic Vascular, Inc. | Low profile resorbable stent |
| US20050149172A1 (en) | 2003-12-22 | 2005-07-07 | Ashish Varma | Minimal injury resorbable stent |
| US7731890B2 (en) * | 2006-06-15 | 2010-06-08 | Advanced Cardiovascular Systems, Inc. | Methods of fabricating stents with enhanced fracture toughness |
| US8501079B2 (en) * | 2009-09-14 | 2013-08-06 | Abbott Cardiovascular Systems Inc. | Controlling crystalline morphology of a bioabsorbable stent |
| US20060020330A1 (en) | 2004-07-26 | 2006-01-26 | Bin Huang | Method of fabricating an implantable medical device with biaxially oriented polymers |
| US7971333B2 (en) | 2006-05-30 | 2011-07-05 | Advanced Cardiovascular Systems, Inc. | Manufacturing process for polymetric stents |
| US8012402B2 (en) | 2008-08-04 | 2011-09-06 | Abbott Cardiovascular Systems Inc. | Tube expansion process for semicrystalline polymers to maximize fracture toughness |
| US20060041102A1 (en) | 2004-08-23 | 2006-02-23 | Advanced Cardiovascular Systems, Inc. | Implantable devices comprising biologically absorbable polymers having constant rate of degradation and methods for fabricating the same |
| CN100555315C (zh) * | 2004-09-21 | 2009-10-28 | 松下电器产业株式会社 | 半导体存储卡 |
| US8585753B2 (en) * | 2006-03-04 | 2013-11-19 | John James Scanlon | Fibrillated biodegradable prosthesis |
| WO2007105067A1 (en) | 2006-03-14 | 2007-09-20 | Arterial Remodeling Technologies, S.A. | Method of monitoring positioning of polymeric stents |
| US7594928B2 (en) * | 2006-05-17 | 2009-09-29 | Boston Scientific Scimed, Inc. | Bioabsorbable stents with reinforced filaments |
| US20070288080A1 (en) * | 2006-06-07 | 2007-12-13 | Maccollum Michael W | Stent expanding device |
| EP3047860B1 (en) | 2006-07-20 | 2024-08-28 | OrbusNeich Medical Pte. Ltd. | Bioabsorbable polymeric composition for a medical device |
| US8394488B2 (en) | 2006-10-06 | 2013-03-12 | Cordis Corporation | Bioabsorbable device having composite structure for accelerating degradation |
| EP2076211A4 (en) | 2006-10-20 | 2015-07-22 | Elixir Medical Corp | LUMINOUS PROSTHESES AND METHODS OF COATING THEREOF |
| US20080103584A1 (en) | 2006-10-25 | 2008-05-01 | Biosensors International Group | Temporal Intraluminal Stent, Methods of Making and Using |
| ATE464995T1 (de) | 2006-11-10 | 2010-05-15 | Dow Global Technologies Inc | Strecken im festkörperzustand einer gefüllten polymerzusammensetzung bis zu einer stabilen hohlraumgrösse und dichte |
| US20080177373A1 (en) | 2007-01-19 | 2008-07-24 | Elixir Medical Corporation | Endoprosthesis structures having supporting features |
| US7704275B2 (en) * | 2007-01-26 | 2010-04-27 | Reva Medical, Inc. | Circumferentially nested expandable device |
| FR2916439B1 (fr) * | 2007-05-23 | 2010-09-10 | Commissariat Energie Atomique | Procede de fabrication d'une vermiculite fortement exfoliee ne necessitant pas l'utilisation de liant organique ou d'additif organique pour etre mis en forme |
| US20090018643A1 (en) | 2007-06-11 | 2009-01-15 | Nanovasc, Inc. | Stents |
| US8317857B2 (en) | 2008-01-10 | 2012-11-27 | Telesis Research, Llc | Biodegradable self-expanding prosthesis |
| US8206635B2 (en) * | 2008-06-20 | 2012-06-26 | Amaranth Medical Pte. | Stent fabrication via tubular casting processes |
| US9119906B2 (en) * | 2008-09-24 | 2015-09-01 | Integran Technologies, Inc. | In-vivo biodegradable medical implant |
| US20100244334A1 (en) * | 2009-03-24 | 2010-09-30 | Contiliano Joseph H | Method of manufacturing a polymeric stent having a circumferential ring configuration |
| US8545742B2 (en) | 2009-08-28 | 2013-10-01 | Abbott Cardiovascular Systems Inc. | Method of fabricating a low crystallinity poly(L-lactide) tube |
| CN201551421U (zh) | 2009-11-06 | 2010-08-18 | 易生科技(北京)有限公司 | 一种血管支架 |
| US8568471B2 (en) | 2010-01-30 | 2013-10-29 | Abbott Cardiovascular Systems Inc. | Crush recoverable polymer scaffolds |
| US8496865B2 (en) | 2010-10-15 | 2013-07-30 | Abbott Cardiovascular Systems Inc. | Method to minimize chain scission and monomer generation in processing of poly(L-lactide) stent |
| WO2013003644A1 (en) * | 2011-06-30 | 2013-01-03 | Elixir Medical Corporation | Biodegradable endoprostheses and methods for their fabrication |
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| GB2512016A (en) | 2014-09-24 |
| NZ707348A (en) | 2018-07-27 |
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| CA2886037A1 (en) | 2014-03-27 |
| JP2019051399A (ja) | 2019-04-04 |
| HK1250690A1 (en) | 2019-01-11 |
| ES2788392T3 (es) | 2020-10-21 |
| AU2013319946B2 (en) | 2018-03-08 |
| AU2013319946A1 (en) | 2015-05-14 |
| GB201217018D0 (en) | 2012-11-07 |
| EP2909003A1 (en) | 2015-08-26 |
| EP2909003B1 (en) | 2018-03-21 |
| EP3345739A2 (en) | 2018-07-11 |
| CA2886037C (en) | 2020-10-06 |
| EP3345739A3 (en) | 2018-09-12 |
| US10299944B2 (en) | 2019-05-28 |
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