ES2665958T3 - Anticuerpos monoclonales contra las variantes de hemoglobina C, S, E y D - Google Patents

Anticuerpos monoclonales contra las variantes de hemoglobina C, S, E y D Download PDF

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Publication number
ES2665958T3
ES2665958T3 ES16155015.7T ES16155015T ES2665958T3 ES 2665958 T3 ES2665958 T3 ES 2665958T3 ES 16155015 T ES16155015 T ES 16155015T ES 2665958 T3 ES2665958 T3 ES 2665958T3
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Prior art keywords
hemoglobin
antibody
variants
glycated
binds
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ES16155015.7T
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English (en)
Spanish (es)
Inventor
Roger Walker
Benedicte Jardin
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Bio Rad Laboratories Inc
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Bio Rad Laboratories Inc
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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721Haemoglobin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721Haemoglobin
    • G01N33/723Glycosylated haemoglobin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666Particle count or volume standard or control [e.g., platelet count standards, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25125Digestion or removing interfering materials

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ES16155015.7T 2009-11-18 2010-11-09 Anticuerpos monoclonales contra las variantes de hemoglobina C, S, E y D Active ES2665958T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US26248809P 2009-11-18 2009-11-18
US262488P 2009-11-18
US12/941,738 US8603828B2 (en) 2009-11-18 2010-11-08 Multiplex immunoassays for hemoglobin, hemoglobin variants, and glycated forms
US941738 2010-11-08

Publications (1)

Publication Number Publication Date
ES2665958T3 true ES2665958T3 (es) 2018-04-30

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
ES16155015.7T Active ES2665958T3 (es) 2009-11-18 2010-11-09 Anticuerpos monoclonales contra las variantes de hemoglobina C, S, E y D

Country Status (8)

Country Link
US (5) US8603828B2 (enExample)
EP (3) EP3301452B1 (enExample)
JP (2) JP6139886B2 (enExample)
AU (3) AU2010322233B2 (enExample)
CA (1) CA2781255C (enExample)
ES (1) ES2665958T3 (enExample)
PT (1) PT3043182T (enExample)
WO (1) WO2011062803A2 (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8603828B2 (en) 2009-11-18 2013-12-10 Bio-Rad Laboratories, Inc. Multiplex immunoassays for hemoglobin, hemoglobin variants, and glycated forms
US11435358B2 (en) 2011-06-23 2022-09-06 Board Of Regents, The University Of Texas System Single molecule peptide sequencing
WO2015099123A1 (ja) * 2013-12-26 2015-07-02 京セラ株式会社 センサ
WO2015143394A1 (en) * 2014-03-20 2015-09-24 Bio-Rad Laboratories, Inc. Glycated protein assay
US10288628B2 (en) 2014-04-11 2019-05-14 Siemens Healthcare Diagnostics Inc. Spectroscopic methods for the detection of glycated hemoglobin
US20160116489A1 (en) * 2014-10-23 2016-04-28 Biomedomics, Inc. Lateral flow immunoassay method of simultaneously detecting hemoglobin s, hemoglobin c, and hemoglobin a in newborns, infants, children, and adults
US10545158B2 (en) * 2014-12-29 2020-01-28 North Carolina State University Multiplexed diagnostic to recognize concentrations of related proteins and peptides
CN114923837B (zh) 2015-02-09 2025-09-19 弹弓生物科学公司 具有可调光学性质的水凝胶颗粒以及使用其的方法
JP6492856B2 (ja) * 2015-03-25 2019-04-03 東ソー株式会社 安定型糖化ヘモグロビンA1cの定量方法
EP3365012A1 (en) * 2015-10-21 2018-08-29 Qoolabs, Inc. Camelid hemoglobin antibodies and methods of use
US10670615B2 (en) 2015-12-04 2020-06-02 Polymer Technology Systems, Inc. Systems and methods for interference correction from hemoglobin variants
US11091004B2 (en) 2016-02-17 2021-08-17 Denso Corporation Air conditioning unit for vehicle
US12345718B2 (en) * 2016-11-04 2025-07-01 Université Paris Est Créteil Val De Marne Method for determining the haemoglobin content of an erythroid cell
US10317413B2 (en) 2016-11-14 2019-06-11 The Board Of Regents Of The University Of Texas System Method and kit for detection of anti-zika virus antibodies
US11535681B2 (en) * 2017-12-15 2022-12-27 Bluebird Bio, Inc. Sickled beta globin antibodies
EP3821010A4 (en) 2018-07-12 2022-04-20 Board of Regents, The University of Texas System Molecular neighborhood detection by oligonucleotides
KR20210068048A (ko) * 2018-09-28 2021-06-08 세키스이 메디칼 가부시키가이샤 당화 헤모글로빈(%)의 측정 방법
JP2022504225A (ja) 2018-10-05 2022-01-13 ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム 固相でのn末端ペプチド捕捉および解放の方法
EP3942059A4 (en) * 2019-03-04 2022-04-20 Siemens Healthcare Diagnostics, Inc. STABILIZATION OF THE SURFACE POLYSACCHARID AREA OF A DRIED REAGENT
US20200284807A1 (en) * 2019-03-05 2020-09-10 Victor Manneh Saturation binding ratiometric assay
CA3165821A1 (en) 2020-01-24 2021-07-29 Jeffrey Kim Compositions and methods for cell-like calibration particles
EP4147049A1 (en) 2020-05-04 2023-03-15 Slingshot Biosciences, Inc. Compositions and methods for passive optical barcoding for multiplexed assays
KR20240116721A (ko) 2021-10-29 2024-07-30 슬링샷 바이오사이언시즈 인코포레이티드 피더 세포 및 합성 항원 제시 세포로서의 하이드로겔 입자
JPWO2023195348A1 (enExample) * 2022-04-04 2023-10-12
WO2023196898A1 (en) * 2022-04-07 2023-10-12 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Beta globin mimetic peptides and their use
AU2023265684A1 (en) 2022-05-05 2024-11-21 Slingshot Biosciences, Inc. Engineered particles as red blood cell mimics and compositions containing same for hematology
CN119546284A (zh) 2022-06-02 2025-02-28 弹弓生物科学公司 凋亡细胞模拟物
EP4608872A2 (en) 2022-10-26 2025-09-03 Slingshot Biosciences, Inc. Size-tunable synthetic particles with tunable optical properties and methods for using the same for immune cell activation
US12461007B2 (en) 2023-08-29 2025-11-04 Slingshot Biosciences, Inc. CD34 stem cell mimics

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2632478A1 (de) 1975-07-23 1977-02-24 Coulter Electronics Verfahren zur erfassung und trennung von antigenen und antikoerperchen im blut und in anderen proben
US4752583A (en) * 1984-11-29 1988-06-21 The United States Of America As Represented By The United States Department Of Energy Monoclonal antibodies to human hemoglobin S and cell lines for the production thereof
US5428754A (en) 1988-03-23 1995-06-27 3Dlabs Ltd Computer system with clock shared between processors executing separate instruction streams
US5922854A (en) * 1991-06-14 1999-07-13 Kumar; Ramesh Purifying Human Hemogloblin from transgenic pig red cells and plasmids containing pig globin nucleic acids
WO1993018407A1 (en) * 1992-03-04 1993-09-16 Abbott Laboratories Determination of glycated hemoglobin by fluorescence quenching
US6043043A (en) * 1993-04-02 2000-03-28 Bayer Corporation Method for the determination of hemoglobin adducts
US6951716B2 (en) * 1995-03-13 2005-10-04 Mark Hechinger Anti-platelet immunoglobulin bead positive control
US6933106B2 (en) * 1995-03-13 2005-08-23 Mark Hechinger Platelet immunoglobulin bead suspension and flow cytometry
EP1015028A2 (en) * 1997-09-19 2000-07-05 Serex, Inc. Methods to improve immunogenicity of antigens and specificity of antibodies
US7271009B1 (en) * 1997-11-18 2007-09-18 Bio-Rad Laboratories, Inc. Multi-analyte diagnostic test for thyroid disorders
EP0965044B1 (en) * 1997-11-18 2003-03-19 Bio-Rad Laboratories, Inc. Multiplex flow immunoassays with magnetic particles as solid phase
WO1999064867A1 (en) * 1997-12-04 1999-12-16 Amersham Pharmacia Biotech Uk Limited Multiple assay method
US20020115116A1 (en) * 2001-02-22 2002-08-22 Yong Song Multiplex protein interaction determinations using glutathione-GST binding
DE60234933D1 (de) * 2001-04-26 2010-02-11 Dako Denmark As Pan-spezifischer monoklonaler antikörper der gegen glycosiliertes hämoglobin gerichtet ist
AU2003223520A1 (en) * 2002-04-12 2003-10-27 Mitokor Targets for therapeutic intervention identified in the mitochondrial proteome
US7326573B2 (en) * 2003-01-10 2008-02-05 Beckman Coulter, Inc. Assay procedures and apparatus
US20040229284A1 (en) * 2003-02-19 2004-11-18 The Regents Of The University Of California Multiplex analysis of proteins
US20040214243A1 (en) * 2003-04-25 2004-10-28 Beckman Coulter, Inc. Differential determination of hemoglobins
US7150995B2 (en) * 2004-01-16 2006-12-19 Metrika, Inc. Methods and systems for point of care bodily fluid analysis
WO2005116607A1 (en) * 2004-05-27 2005-12-08 Monash University A method for the rapid analysis of polypeptides
JP2006052480A (ja) 2004-08-10 2006-02-23 Nisshinbo Ind Inc セルロース系繊維含有布帛の加工方法及びセルロース系繊維含有布帛
GB0502068D0 (en) * 2005-02-01 2005-03-09 King S College London Screening method
EP1889906A4 (en) 2005-06-03 2009-06-03 Nipro Corp VECTOR WITH HIGH COPY AND HIGH EXPRESSION AND WITH METHIONINAMINOPEPTIDASE GENE INCLUDED
US7521244B2 (en) * 2006-10-26 2009-04-21 Bionostics, Inc. Standard reference solutions
WO2009067421A1 (en) * 2007-11-20 2009-05-28 Siemens Heathcare Diagnostics Inc. Methods for the detection of glycated hemoglobin
US8260556B2 (en) 2008-08-21 2012-09-04 Bio-Rad Laboratories, Inc. Calibration surface method for determination on of analyte ratios
CA2765457A1 (en) * 2009-07-07 2011-01-13 Uvic Industry Partnerships Inc. Methods for early detection of blood disorders
US8603828B2 (en) * 2009-11-18 2013-12-10 Bio-Rad Laboratories, Inc. Multiplex immunoassays for hemoglobin, hemoglobin variants, and glycated forms

Also Published As

Publication number Publication date
JP2013511717A (ja) 2013-04-04
EP3043182A1 (en) 2016-07-13
EP3043182B1 (en) 2018-01-17
US10088488B2 (en) 2018-10-02
EP3301452B1 (en) 2020-01-08
CA2781255A1 (en) 2011-05-26
US8603828B2 (en) 2013-12-10
EP3301452A1 (en) 2018-04-04
AU2010322233A1 (en) 2012-06-21
AU2019200070B2 (en) 2020-07-16
US20110117670A1 (en) 2011-05-19
AU2019200070A1 (en) 2019-01-31
JP6139886B2 (ja) 2017-05-31
AU2017200733B2 (en) 2018-10-11
US9213034B2 (en) 2015-12-15
CA2781255C (en) 2017-08-01
AU2017200733A1 (en) 2017-02-23
EP2502080A2 (en) 2012-09-26
EP2502080B1 (en) 2016-04-13
EP2502080A4 (en) 2013-03-27
US9605060B2 (en) 2017-03-28
US20170176462A1 (en) 2017-06-22
US20160068594A1 (en) 2016-03-10
US20140073532A1 (en) 2014-03-13
WO2011062803A2 (en) 2011-05-26
PT3043182T (pt) 2018-04-23
WO2011062803A3 (en) 2011-07-28
US11262366B2 (en) 2022-03-01
AU2010322233B2 (en) 2016-11-03
JP2016028254A (ja) 2016-02-25
US20190018023A1 (en) 2019-01-17

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