PT3043182T - Anticorpos monoclonais para variantes de hemoglobina c, s, e e d - Google Patents
Anticorpos monoclonais para variantes de hemoglobina c, s, e e dInfo
- Publication number
- PT3043182T PT3043182T PT161550157T PT16155015T PT3043182T PT 3043182 T PT3043182 T PT 3043182T PT 161550157 T PT161550157 T PT 161550157T PT 16155015 T PT16155015 T PT 16155015T PT 3043182 T PT3043182 T PT 3043182T
- Authority
- PT
- Portugal
- Prior art keywords
- monoclonal antibodies
- hemoglobin variants
- hemoglobin
- variants
- monoclonal
- Prior art date
Links
- 102000001554 Hemoglobins Human genes 0.000 title 1
- 108010054147 Hemoglobins Proteins 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
- G01N33/723—Glycosylated haemoglobin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25125—Digestion or removing interfering materials
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26248809P | 2009-11-18 | 2009-11-18 | |
| US12/941,738 US8603828B2 (en) | 2009-11-18 | 2010-11-08 | Multiplex immunoassays for hemoglobin, hemoglobin variants, and glycated forms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3043182T true PT3043182T (pt) | 2018-04-23 |
Family
ID=44011571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT161550157T PT3043182T (pt) | 2009-11-18 | 2010-11-09 | Anticorpos monoclonais para variantes de hemoglobina c, s, e e d |
Country Status (8)
| Country | Link |
|---|---|
| US (5) | US8603828B2 (enExample) |
| EP (3) | EP3301452B1 (enExample) |
| JP (2) | JP6139886B2 (enExample) |
| AU (3) | AU2010322233B2 (enExample) |
| CA (1) | CA2781255C (enExample) |
| ES (1) | ES2665958T3 (enExample) |
| PT (1) | PT3043182T (enExample) |
| WO (1) | WO2011062803A2 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8603828B2 (en) | 2009-11-18 | 2013-12-10 | Bio-Rad Laboratories, Inc. | Multiplex immunoassays for hemoglobin, hemoglobin variants, and glycated forms |
| US11435358B2 (en) | 2011-06-23 | 2022-09-06 | Board Of Regents, The University Of Texas System | Single molecule peptide sequencing |
| WO2015099123A1 (ja) * | 2013-12-26 | 2015-07-02 | 京セラ株式会社 | センサ |
| WO2015143394A1 (en) * | 2014-03-20 | 2015-09-24 | Bio-Rad Laboratories, Inc. | Glycated protein assay |
| US10288628B2 (en) | 2014-04-11 | 2019-05-14 | Siemens Healthcare Diagnostics Inc. | Spectroscopic methods for the detection of glycated hemoglobin |
| US20160116489A1 (en) * | 2014-10-23 | 2016-04-28 | Biomedomics, Inc. | Lateral flow immunoassay method of simultaneously detecting hemoglobin s, hemoglobin c, and hemoglobin a in newborns, infants, children, and adults |
| US10545158B2 (en) * | 2014-12-29 | 2020-01-28 | North Carolina State University | Multiplexed diagnostic to recognize concentrations of related proteins and peptides |
| CN114923837B (zh) | 2015-02-09 | 2025-09-19 | 弹弓生物科学公司 | 具有可调光学性质的水凝胶颗粒以及使用其的方法 |
| JP6492856B2 (ja) * | 2015-03-25 | 2019-04-03 | 東ソー株式会社 | 安定型糖化ヘモグロビンＡ１ｃの定量方法 |
| EP3365012A1 (en) * | 2015-10-21 | 2018-08-29 | Qoolabs, Inc. | Camelid hemoglobin antibodies and methods of use |
| US10670615B2 (en) | 2015-12-04 | 2020-06-02 | Polymer Technology Systems, Inc. | Systems and methods for interference correction from hemoglobin variants |
| US11091004B2 (en) | 2016-02-17 | 2021-08-17 | Denso Corporation | Air conditioning unit for vehicle |
| US12345718B2 (en) * | 2016-11-04 | 2025-07-01 | Université Paris Est Créteil Val De Marne | Method for determining the haemoglobin content of an erythroid cell |
| US10317413B2 (en) | 2016-11-14 | 2019-06-11 | The Board Of Regents Of The University Of Texas System | Method and kit for detection of anti-zika virus antibodies |
| US11535681B2 (en) * | 2017-12-15 | 2022-12-27 | Bluebird Bio, Inc. | Sickled beta globin antibodies |
| EP3821010A4 (en) | 2018-07-12 | 2022-04-20 | Board of Regents, The University of Texas System | Molecular neighborhood detection by oligonucleotides |
| KR20210068048A (ko) * | 2018-09-28 | 2021-06-08 | 세키스이 메디칼 가부시키가이샤 | 당화 헤모글로빈(％)의 측정 방법 |
| JP2022504225A (ja) | 2018-10-05 | 2022-01-13 | ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム | 固相でのｎ末端ペプチド捕捉および解放の方法 |
| EP3942059A4 (en) * | 2019-03-04 | 2022-04-20 | Siemens Healthcare Diagnostics, Inc. | STABILIZATION OF THE SURFACE POLYSACCHARID AREA OF A DRIED REAGENT |
| US20200284807A1 (en) * | 2019-03-05 | 2020-09-10 | Victor Manneh | Saturation binding ratiometric assay |
| CA3165821A1 (en) | 2020-01-24 | 2021-07-29 | Jeffrey Kim | Compositions and methods for cell-like calibration particles |
| EP4147049A1 (en) | 2020-05-04 | 2023-03-15 | Slingshot Biosciences, Inc. | Compositions and methods for passive optical barcoding for multiplexed assays |
| KR20240116721A (ko) | 2021-10-29 | 2024-07-30 | 슬링샷 바이오사이언시즈 인코포레이티드 | 피더 세포 및 합성 항원 제시 세포로서의 하이드로겔 입자 |
| JPWO2023195348A1 (enExample) * | 2022-04-04 | 2023-10-12 | ||
| WO2023196898A1 (en) * | 2022-04-07 | 2023-10-12 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Beta globin mimetic peptides and their use |
| AU2023265684A1 (en) | 2022-05-05 | 2024-11-21 | Slingshot Biosciences, Inc. | Engineered particles as red blood cell mimics and compositions containing same for hematology |
| CN119546284A (zh) | 2022-06-02 | 2025-02-28 | 弹弓生物科学公司 | 凋亡细胞模拟物 |
| EP4608872A2 (en) | 2022-10-26 | 2025-09-03 | Slingshot Biosciences, Inc. | Size-tunable synthetic particles with tunable optical properties and methods for using the same for immune cell activation |
| US12461007B2 (en) | 2023-08-29 | 2025-11-04 | Slingshot Biosciences, Inc. | CD34 stem cell mimics |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2632478A1 (de) | 1975-07-23 | 1977-02-24 | Coulter Electronics | Verfahren zur erfassung und trennung von antigenen und antikoerperchen im blut und in anderen proben |
| US4752583A (en) * | 1984-11-29 | 1988-06-21 | The United States Of America As Represented By The United States Department Of Energy | Monoclonal antibodies to human hemoglobin S and cell lines for the production thereof |
| US5428754A (en) | 1988-03-23 | 1995-06-27 | 3Dlabs Ltd | Computer system with clock shared between processors executing separate instruction streams |
| US5922854A (en) * | 1991-06-14 | 1999-07-13 | Kumar; Ramesh | Purifying Human Hemogloblin from transgenic pig red cells and plasmids containing pig globin nucleic acids |
| WO1993018407A1 (en) * | 1992-03-04 | 1993-09-16 | Abbott Laboratories | Determination of glycated hemoglobin by fluorescence quenching |
| US6043043A (en) * | 1993-04-02 | 2000-03-28 | Bayer Corporation | Method for the determination of hemoglobin adducts |
| US6951716B2 (en) * | 1995-03-13 | 2005-10-04 | Mark Hechinger | Anti-platelet immunoglobulin bead positive control |
| US6933106B2 (en) * | 1995-03-13 | 2005-08-23 | Mark Hechinger | Platelet immunoglobulin bead suspension and flow cytometry |
| EP1015028A2 (en) * | 1997-09-19 | 2000-07-05 | Serex, Inc. | Methods to improve immunogenicity of antigens and specificity of antibodies |
| US7271009B1 (en) * | 1997-11-18 | 2007-09-18 | Bio-Rad Laboratories, Inc. | Multi-analyte diagnostic test for thyroid disorders |
| EP0965044B1 (en) * | 1997-11-18 | 2003-03-19 | Bio-Rad Laboratories, Inc. | Multiplex flow immunoassays with magnetic particles as solid phase |
| WO1999064867A1 (en) * | 1997-12-04 | 1999-12-16 | Amersham Pharmacia Biotech Uk Limited | Multiple assay method |
| US20020115116A1 (en) * | 2001-02-22 | 2002-08-22 | Yong Song | Multiplex protein interaction determinations using glutathione-GST binding |
| DE60234933D1 (de) * | 2001-04-26 | 2010-02-11 | Dako Denmark As | Pan-spezifischer monoklonaler antikörper der gegen glycosiliertes hämoglobin gerichtet ist |
| AU2003223520A1 (en) * | 2002-04-12 | 2003-10-27 | Mitokor | Targets for therapeutic intervention identified in the mitochondrial proteome |
| US7326573B2 (en) * | 2003-01-10 | 2008-02-05 | Beckman Coulter, Inc. | Assay procedures and apparatus |
| US20040229284A1 (en) * | 2003-02-19 | 2004-11-18 | The Regents Of The University Of California | Multiplex analysis of proteins |
| US20040214243A1 (en) * | 2003-04-25 | 2004-10-28 | Beckman Coulter, Inc. | Differential determination of hemoglobins |
| US7150995B2 (en) * | 2004-01-16 | 2006-12-19 | Metrika, Inc. | Methods and systems for point of care bodily fluid analysis |
| WO2005116607A1 (en) * | 2004-05-27 | 2005-12-08 | Monash University | A method for the rapid analysis of polypeptides |
| JP2006052480A (ja) | 2004-08-10 | 2006-02-23 | Nisshinbo Ind Inc | セルロース系繊維含有布帛の加工方法及びセルロース系繊維含有布帛 |
| GB0502068D0 (en) * | 2005-02-01 | 2005-03-09 | King S College London | Screening method |
| EP1889906A4 (en) | 2005-06-03 | 2009-06-03 | Nipro Corp | VECTOR WITH HIGH COPY AND HIGH EXPRESSION AND WITH METHIONINAMINOPEPTIDASE GENE INCLUDED |
| US7521244B2 (en) * | 2006-10-26 | 2009-04-21 | Bionostics, Inc. | Standard reference solutions |
| WO2009067421A1 (en) * | 2007-11-20 | 2009-05-28 | Siemens Heathcare Diagnostics Inc. | Methods for the detection of glycated hemoglobin |
| US8260556B2 (en) | 2008-08-21 | 2012-09-04 | Bio-Rad Laboratories, Inc. | Calibration surface method for determination on of analyte ratios |
| CA2765457A1 (en) * | 2009-07-07 | 2011-01-13 | Uvic Industry Partnerships Inc. | Methods for early detection of blood disorders |
| US8603828B2 (en) * | 2009-11-18 | 2013-12-10 | Bio-Rad Laboratories, Inc. | Multiplex immunoassays for hemoglobin, hemoglobin variants, and glycated forms |
-
2010
- 2010-11-08 US US12/941,738 patent/US8603828B2/en active Active
- 2010-11-09 WO PCT/US2010/055952 patent/WO2011062803A2/en not_active Ceased
- 2010-11-09 EP EP17201427.6A patent/EP3301452B1/en active Active
- 2010-11-09 EP EP16155015.7A patent/EP3043182B1/en active Active
- 2010-11-09 PT PT161550157T patent/PT3043182T/pt unknown
- 2010-11-09 EP EP10832004.5A patent/EP2502080B1/en active Active
- 2010-11-09 ES ES16155015.7T patent/ES2665958T3/es active Active
- 2010-11-09 AU AU2010322233A patent/AU2010322233B2/en not_active Ceased
- 2010-11-09 CA CA2781255A patent/CA2781255C/en active Active
- 2010-11-09 JP JP2012539940A patent/JP6139886B2/ja active Active
-
2013
- 2013-11-15 US US14/081,799 patent/US9213034B2/en active Active
-
2015
- 2015-10-23 JP JP2015209371A patent/JP2016028254A/ja active Pending
- 2015-11-20 US US14/947,939 patent/US9605060B2/en active Active
-
2017
- 2017-02-03 AU AU2017200733A patent/AU2017200733B2/en not_active Ceased
- 2017-02-24 US US15/441,455 patent/US10088488B2/en active Active
-
2018
- 2018-09-27 US US16/145,021 patent/US11262366B2/en active Active
-
2019
- 2019-01-07 AU AU2019200070A patent/AU2019200070B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2013511717A (ja) | 2013-04-04 |
| EP3043182A1 (en) | 2016-07-13 |
| EP3043182B1 (en) | 2018-01-17 |
| US10088488B2 (en) | 2018-10-02 |
| EP3301452B1 (en) | 2020-01-08 |
| CA2781255A1 (en) | 2011-05-26 |
| US8603828B2 (en) | 2013-12-10 |
| EP3301452A1 (en) | 2018-04-04 |
| AU2010322233A1 (en) | 2012-06-21 |
| AU2019200070B2 (en) | 2020-07-16 |
| US20110117670A1 (en) | 2011-05-19 |
| AU2019200070A1 (en) | 2019-01-31 |
| JP6139886B2 (ja) | 2017-05-31 |
| AU2017200733B2 (en) | 2018-10-11 |
| US9213034B2 (en) | 2015-12-15 |
| CA2781255C (en) | 2017-08-01 |
| AU2017200733A1 (en) | 2017-02-23 |
| EP2502080A2 (en) | 2012-09-26 |
| EP2502080B1 (en) | 2016-04-13 |
| EP2502080A4 (en) | 2013-03-27 |
| US9605060B2 (en) | 2017-03-28 |
| US20170176462A1 (en) | 2017-06-22 |
| US20160068594A1 (en) | 2016-03-10 |
| US20140073532A1 (en) | 2014-03-13 |
| WO2011062803A2 (en) | 2011-05-26 |
| WO2011062803A3 (en) | 2011-07-28 |
| US11262366B2 (en) | 2022-03-01 |
| AU2010322233B2 (en) | 2016-11-03 |
| JP2016028254A (ja) | 2016-02-25 |
| ES2665958T3 (es) | 2018-04-30 |
| US20190018023A1 (en) | 2019-01-17 |
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