ES2663094T3 - Compuesto polímero duradero de elevada resistencia mecánica adecuado para implante y artículos producidos a partir del mismo - Google Patents
Compuesto polímero duradero de elevada resistencia mecánica adecuado para implante y artículos producidos a partir del mismo Download PDFInfo
- Publication number
- ES2663094T3 ES2663094T3 ES12764638.8T ES12764638T ES2663094T3 ES 2663094 T3 ES2663094 T3 ES 2663094T3 ES 12764638 T ES12764638 T ES 12764638T ES 2663094 T3 ES2663094 T3 ES 2663094T3
- Authority
- ES
- Spain
- Prior art keywords
- leaflet
- elastomer
- approximately
- fluoropolymer
- valve
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 150000001875 compounds Chemical class 0.000 title claims description 20
- 229920000642 polymer Polymers 0.000 title description 21
- 239000007943 implant Substances 0.000 title description 6
- 229920002313 fluoropolymer Polymers 0.000 claims abstract description 70
- 239000004811 fluoropolymer Substances 0.000 claims abstract description 70
- 229920001971 elastomer Polymers 0.000 claims abstract description 67
- 239000000806 elastomer Substances 0.000 claims abstract description 67
- 239000011148 porous material Substances 0.000 claims abstract description 46
- 239000002131 composite material Substances 0.000 claims abstract description 42
- 230000017531 blood circulation Effects 0.000 claims abstract description 11
- 238000000034 method Methods 0.000 claims description 30
- 229920001343 polytetrafluoroethylene Polymers 0.000 claims description 21
- 229920001973 fluoroelastomer Polymers 0.000 claims description 17
- 239000004810 polytetrafluoroethylene Substances 0.000 claims description 17
- 229920001577 copolymer Polymers 0.000 claims description 8
- BFKJFAAPBSQJPD-UHFFFAOYSA-N tetrafluoroethene Chemical group FC(F)=C(F)F BFKJFAAPBSQJPD-UHFFFAOYSA-N 0.000 claims description 6
- BLTXWCKMNMYXEA-UHFFFAOYSA-N 1,1,2-trifluoro-2-(trifluoromethoxy)ethene Chemical compound FC(F)=C(F)OC(F)(F)F BLTXWCKMNMYXEA-UHFFFAOYSA-N 0.000 claims description 5
- 239000002904 solvent Substances 0.000 claims description 5
- 230000000295 complement effect Effects 0.000 claims description 2
- 239000006185 dispersion Substances 0.000 claims description 2
- 230000000379 polymerizing effect Effects 0.000 claims description 2
- 229920000295 expanded polytetrafluoroethylene Polymers 0.000 claims 1
- 239000012528 membrane Substances 0.000 description 63
- 239000000463 material Substances 0.000 description 52
- 230000006835 compression Effects 0.000 description 21
- 238000007906 compression Methods 0.000 description 21
- 210000003709 heart valve Anatomy 0.000 description 20
- 238000012360 testing method Methods 0.000 description 18
- 239000000835 fiber Substances 0.000 description 16
- 239000004812 Fluorinated ethylene propylene Substances 0.000 description 15
- 229920009441 perflouroethylene propylene Polymers 0.000 description 15
- 229920001296 polysiloxane Polymers 0.000 description 12
- 230000015572 biosynthetic process Effects 0.000 description 11
- 238000005259 measurement Methods 0.000 description 10
- 230000008569 process Effects 0.000 description 10
- 229920001169 thermoplastic Polymers 0.000 description 9
- 230000015556 catabolic process Effects 0.000 description 8
- 239000011248 coating agent Substances 0.000 description 8
- 238000000576 coating method Methods 0.000 description 8
- 238000006731 degradation reaction Methods 0.000 description 8
- 239000004416 thermosoftening plastic Substances 0.000 description 8
- 230000000712 assembly Effects 0.000 description 7
- 238000000429 assembly Methods 0.000 description 7
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 6
- 239000011159 matrix material Substances 0.000 description 6
- 230000008859 change Effects 0.000 description 5
- 238000005520 cutting process Methods 0.000 description 5
- 239000000203 mixture Substances 0.000 description 5
- -1 polytetrafluoroethylene Polymers 0.000 description 5
- 238000009423 ventilation Methods 0.000 description 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
- 238000005452 bending Methods 0.000 description 4
- 229910052751 metal Inorganic materials 0.000 description 4
- 239000002184 metal Substances 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 229910000619 316 stainless steel Inorganic materials 0.000 description 3
- 230000000052 comparative effect Effects 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 229910052742 iron Inorganic materials 0.000 description 3
- 230000007246 mechanism Effects 0.000 description 3
- 238000005476 soldering Methods 0.000 description 3
- 230000000007 visual effect Effects 0.000 description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- 229910000831 Steel Inorganic materials 0.000 description 2
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 2
- 230000004075 alteration Effects 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000002308 calcification Effects 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 238000012512 characterization method Methods 0.000 description 2
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 239000001307 helium Substances 0.000 description 2
- 229910052734 helium Inorganic materials 0.000 description 2
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 2
- 230000000004 hemodynamic effect Effects 0.000 description 2
- 238000002513 implantation Methods 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000000178 monomer Substances 0.000 description 2
- 238000000465 moulding Methods 0.000 description 2
- 229910052757 nitrogen Inorganic materials 0.000 description 2
- 230000002093 peripheral effect Effects 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 238000001179 sorption measurement Methods 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 239000010959 steel Substances 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 230000002861 ventricular Effects 0.000 description 2
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 239000004687 Nylon copolymer Substances 0.000 description 1
- 229920002367 Polyisobutene Polymers 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000012298 atmosphere Substances 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 229920000249 biocompatible polymer Polymers 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000001010 compromised effect Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000035487 diastolic blood pressure Effects 0.000 description 1
- 230000003205 diastolic effect Effects 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000013536 elastomeric material Substances 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- HQQADJVZYDDRJT-UHFFFAOYSA-N ethene;prop-1-ene Chemical group C=C.CC=C HQQADJVZYDDRJT-UHFFFAOYSA-N 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 238000009661 fatigue test Methods 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 229920001519 homopolymer Polymers 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 239000011256 inorganic filler Substances 0.000 description 1
- 229910003475 inorganic filler Inorganic materials 0.000 description 1
- 238000005304 joining Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000006082 mold release agent Substances 0.000 description 1
- 238000009832 plasma treatment Methods 0.000 description 1
- 238000013001 point bending Methods 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920002689 polyvinyl acetate Polymers 0.000 description 1
- 239000011118 polyvinyl acetate Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 238000005488 sandblasting Methods 0.000 description 1
- 238000001878 scanning electron micrograph Methods 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 239000004945 silicone rubber Substances 0.000 description 1
- 238000013517 stratification Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000035488 systolic blood pressure Effects 0.000 description 1
- 238000009864 tensile test Methods 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 229920001187 thermosetting polymer Polymers 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- ZSDSQXJSNMTJDA-UHFFFAOYSA-N trifluralin Chemical compound CCCN(CCC)C1=C([N+]([O-])=O)C=C(C(F)(F)F)C=C1[N+]([O-])=O ZSDSQXJSNMTJDA-UHFFFAOYSA-N 0.000 description 1
- 150000003673 urethanes Chemical class 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
- A61F2/2415—Manufacturing methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
- A61F2/2418—Scaffolds therefor, e.g. support stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2469—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with resilient valve members, e.g. conical spiral
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2472—Devices for testing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2475—Venous valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0076—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof multilayered, e.g. laminated structures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2220/005—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements using adhesives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0004—Rounded shapes, e.g. with rounded corners
- A61F2230/0006—Rounded shapes, e.g. with rounded corners circular
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0004—Rounded shapes, e.g. with rounded corners
- A61F2230/0013—Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0028—Shapes in the form of latin or greek characters
- A61F2230/0054—V-shaped
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/20—Materials or treatment for tissue regeneration for reconstruction of the heart, e.g. heart valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/025—Other specific inorganic materials not covered by A61L27/04 - A61L27/12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Composite Materials (AREA)
- Materials Engineering (AREA)
- Manufacturing & Machinery (AREA)
- Dispersion Chemistry (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Laminated Bodies (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201113078774 | 2011-04-01 | ||
| US13/078,774 US8961599B2 (en) | 2011-04-01 | 2011-04-01 | Durable high strength polymer composite suitable for implant and articles produced therefrom |
| PCT/US2012/031417 WO2012135603A2 (en) | 2011-04-01 | 2012-03-30 | Durable high strength polymer composite suitable for implant and articles produced therefrom |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2663094T3 true ES2663094T3 (es) | 2018-04-11 |
Family
ID=46928248
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES12764638.8T Active ES2663094T3 (es) | 2011-04-01 | 2012-03-30 | Compuesto polímero duradero de elevada resistencia mecánica adecuado para implante y artículos producidos a partir del mismo |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US8961599B2 (enExample) |
| EP (2) | EP2694123B1 (enExample) |
| JP (3) | JP6051202B2 (enExample) |
| KR (2) | KR101994463B1 (enExample) |
| CN (2) | CN106668949B (enExample) |
| AU (1) | AU2012236318B2 (enExample) |
| BR (1) | BR112013025114A2 (enExample) |
| CA (2) | CA3039324A1 (enExample) |
| ES (1) | ES2663094T3 (enExample) |
| HK (1) | HK1254143A1 (enExample) |
| RU (1) | RU2013148783A (enExample) |
| WO (1) | WO2012135603A2 (enExample) |
Families Citing this family (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2788453T3 (es) | 2007-06-04 | 2020-10-21 | St Jude Medical Llc | Válvulas cardíacas protésicas |
| HUE047246T2 (hu) | 2008-06-06 | 2020-04-28 | Edwards Lifesciences Corp | Kis profilú transzkatéteres szívbillentyû |
| US8579964B2 (en) | 2010-05-05 | 2013-11-12 | Neovasc Inc. | Transcatheter mitral valve prosthesis |
| US9744033B2 (en) | 2011-04-01 | 2017-08-29 | W.L. Gore & Associates, Inc. | Elastomeric leaflet for prosthetic heart valves |
| US9801712B2 (en) * | 2011-04-01 | 2017-10-31 | W. L. Gore & Associates, Inc. | Coherent single layer high strength synthetic polymer composites for prosthetic valves |
| US8961599B2 (en) | 2011-04-01 | 2015-02-24 | W. L. Gore & Associates, Inc. | Durable high strength polymer composite suitable for implant and articles produced therefrom |
| US20130197631A1 (en) | 2011-04-01 | 2013-08-01 | W. L. Gore & Associates, Inc. | Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom |
| US8945212B2 (en) | 2011-04-01 | 2015-02-03 | W. L. Gore & Associates, Inc. | Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom |
| US9554900B2 (en) * | 2011-04-01 | 2017-01-31 | W. L. Gore & Associates, Inc. | Durable high strength polymer composites suitable for implant and articles produced therefrom |
| US9308087B2 (en) | 2011-04-28 | 2016-04-12 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
| US9554897B2 (en) | 2011-04-28 | 2017-01-31 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
| US9554806B2 (en) | 2011-09-16 | 2017-01-31 | W. L. Gore & Associates, Inc. | Occlusive devices |
| US9539360B2 (en) * | 2011-10-07 | 2017-01-10 | W. L. Gore & Associaes, Inc. | Puncturable and resealable graft |
| DE102011117892A1 (de) * | 2011-10-31 | 2013-05-02 | Berlin Heart Gmbh | Verbindungselement zum Montieren einer Blutpumpe oder einer Kanüle an einem Herzen |
| US9345573B2 (en) | 2012-05-30 | 2016-05-24 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
| US9283072B2 (en) | 2012-07-25 | 2016-03-15 | W. L. Gore & Associates, Inc. | Everting transcatheter valve and methods |
| US10376360B2 (en) | 2012-07-27 | 2019-08-13 | W. L. Gore & Associates, Inc. | Multi-frame prosthetic valve apparatus and methods |
| US10321986B2 (en) | 2012-12-19 | 2019-06-18 | W. L. Gore & Associates, Inc. | Multi-frame prosthetic heart valve |
| US10966820B2 (en) * | 2012-12-19 | 2021-04-06 | W. L. Gore & Associates, Inc. | Geometric control of bending character in prosthetic heart valve leaflets |
| US9101469B2 (en) | 2012-12-19 | 2015-08-11 | W. L. Gore & Associates, Inc. | Prosthetic heart valve with leaflet shelving |
| US9737398B2 (en) | 2012-12-19 | 2017-08-22 | W. L. Gore & Associates, Inc. | Prosthetic valves, frames and leaflets and methods thereof |
| US9144492B2 (en) * | 2012-12-19 | 2015-09-29 | W. L. Gore & Associates, Inc. | Truncated leaflet for prosthetic heart valves, preformed valve |
| US9968443B2 (en) | 2012-12-19 | 2018-05-15 | W. L. Gore & Associates, Inc. | Vertical coaptation zone in a planar portion of prosthetic heart valve leaflet |
| US9398952B2 (en) | 2012-12-19 | 2016-07-26 | W. L. Gore & Associates, Inc. | Planar zone in prosthetic heart valve leaflet |
| US10039638B2 (en) | 2012-12-19 | 2018-08-07 | W. L. Gore & Associates, Inc. | Geometric prosthetic heart valves |
| WO2014163795A1 (en) * | 2013-03-13 | 2014-10-09 | W. L. Gore & Associates, Inc. | Durable high strength polymer composites suitable for implant and articles produced therefrom |
| EP2968675A1 (en) * | 2013-03-13 | 2016-01-20 | W. L. Gore & Associates, Inc. | Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom |
| CA3049221A1 (en) * | 2013-03-13 | 2014-10-02 | William C. Bruchman | Elastomeric leaflet for prosthetic heart valves |
| US9681951B2 (en) | 2013-03-14 | 2017-06-20 | Edwards Lifesciences Cardiaq Llc | Prosthesis with outer skirt and anchors |
| US9572665B2 (en) | 2013-04-04 | 2017-02-21 | Neovasc Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
| US11911258B2 (en) | 2013-06-26 | 2024-02-27 | W. L. Gore & Associates, Inc. | Space filling devices |
| US9504565B2 (en) | 2013-12-06 | 2016-11-29 | W. L. Gore & Associates, Inc. | Asymmetric opening and closing prosthetic valve leaflet |
| EP3182929B1 (en) | 2014-08-18 | 2023-08-09 | Edwards Lifesciences Corporation | Frame with integral sewing cuff for prosthetic valves |
| US9827094B2 (en) | 2014-09-15 | 2017-11-28 | W. L. Gore & Associates, Inc. | Prosthetic heart valve with retention elements |
| US10507101B2 (en) * | 2014-10-13 | 2019-12-17 | W. L. Gore & Associates, Inc. | Valved conduit |
| US9937037B2 (en) | 2014-12-18 | 2018-04-10 | W. L. Gore & Associates, Inc. | Prosthetic valved conduits with mechanically coupled leaflets |
| JP6813494B2 (ja) * | 2015-02-13 | 2021-01-13 | ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティドＷ．Ｌ． Ｇｏｒｅ ＆ Ａｓｓｏｃｉａｔｅｓ， Ｉｎｃｏｒｐｏｒａｔｅｄ | 人工弁用のコヒーレントシングルレイヤ高強度合成ポリマー複合体 |
| US10232564B2 (en) * | 2015-04-29 | 2019-03-19 | Edwards Lifesciences Corporation | Laminated sealing member for prosthetic heart valve |
| HK1250897A1 (zh) | 2015-05-14 | 2019-01-18 | W. L. Gore & Associates, Inc. | 用於心耳的堵塞的装置 |
| US10022223B2 (en) | 2015-10-06 | 2018-07-17 | W. L. Gore & Associates, Inc. | Leaflet support devices and methods of making and using the same |
| WO2017100927A1 (en) | 2015-12-15 | 2017-06-22 | Neovasc Tiara Inc. | Transseptal delivery system |
| US9968447B2 (en) * | 2016-01-22 | 2018-05-15 | Medtronic Vascular, Inc. | Bioprosthetic tissue for use as a prosthetic valve leaflet and method of preparing |
| CN108882981B (zh) | 2016-01-29 | 2021-08-10 | 内奥瓦斯克迪亚拉公司 | 用于防止流出阻塞的假体瓣膜 |
| CN109996581B (zh) | 2016-11-21 | 2021-10-15 | 内奥瓦斯克迪亚拉公司 | 用于快速收回经导管心脏瓣膜递送系统的方法和系统 |
| US11351058B2 (en) | 2017-03-17 | 2022-06-07 | W. L. Gore & Associates, Inc. | Glaucoma treatment systems and methods |
| US10952842B2 (en) | 2017-06-07 | 2021-03-23 | W. L. Gore & Associates, Inc. | Prosthetic valve with improved washout |
| PL3644904T3 (pl) | 2017-06-30 | 2025-06-30 | Ohio State Innovation Foundation | Protetyczna zastawka serca o konstrukcji trójpłatkowej do stosowania w zabiegach przezskórnej wymiany zastawki |
| US12458491B2 (en) | 2017-06-30 | 2025-11-04 | Ohio State Innovation Foundation | Methods to improve the durability of polymeric heart valves |
| CA3073834A1 (en) | 2017-08-25 | 2019-02-28 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
| AU2018334191B2 (en) | 2017-09-12 | 2021-04-08 | Edwards Lifesciences Corporation | Leaflet frame attachment for prosthetic valves |
| CA3178271A1 (en) | 2017-09-27 | 2019-04-04 | W.L. Gore & Associates, Inc. | Prosthetic valve with expandable frame and associated systems and methods |
| CA3155761C (en) | 2017-09-27 | 2025-11-18 | Gore & Ass | Prosthetic valves with mechanically coupled leaflets |
| JP7036912B2 (ja) | 2017-10-13 | 2022-03-15 | ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティド | 嵌込式人工弁および送達システム |
| US11173023B2 (en) | 2017-10-16 | 2021-11-16 | W. L. Gore & Associates, Inc. | Medical devices and anchors therefor |
| EP3703768A1 (en) * | 2017-10-31 | 2020-09-09 | W. L. Gore & Associates, Inc. | Synthetic prosthetic valve leaflet |
| US11154397B2 (en) | 2017-10-31 | 2021-10-26 | W. L. Gore & Associates, Inc. | Jacket for surgical heart valve |
| AU2018362080B2 (en) | 2017-10-31 | 2021-09-30 | Edwards Lifesciences Corporation | Valved conduit |
| US10987218B2 (en) | 2017-10-31 | 2021-04-27 | W. L. Gore & Associates, Inc. | Transcatheter deployment systems and associated methods |
| CA3078608C (en) | 2017-10-31 | 2023-03-28 | W.L. Gore & Associates, Inc. | Prosthetic heart valve |
| US11439502B2 (en) * | 2017-10-31 | 2022-09-13 | W. L. Gore & Associates, Inc. | Medical valve and leaflet promoting tissue ingrowth |
| US11166811B2 (en) | 2018-03-02 | 2021-11-09 | James Yashu Coe | Transcatheter valve |
| WO2019224221A1 (en) | 2018-05-21 | 2019-11-28 | Aran Biomedical Teoranta | Insertable medical devices with low profile composite coverings |
| AU2019290674B2 (en) | 2018-06-20 | 2022-08-18 | W. L. Gore & Associates, Inc. | Support structure for an implantable device with enhanced compressive stiffness region(s) |
| AU2019333136B2 (en) | 2018-08-29 | 2022-11-17 | W. L. Gore & Associates, Inc. | Drug therapy delivery systems and methods |
| CN112169018A (zh) * | 2018-09-25 | 2021-01-05 | 湖南博隽生物医药有限公司 | 一种抗血栓心脏瓣膜替换物 |
| USD977642S1 (en) | 2018-10-29 | 2023-02-07 | W. L. Gore & Associates, Inc. | Pulmonary valve conduit |
| USD926322S1 (en) | 2018-11-07 | 2021-07-27 | W. L. Gore & Associates, Inc. | Heart valve cover |
| AU2019374743B2 (en) | 2018-11-08 | 2022-03-03 | Neovasc Tiara Inc. | Ventricular deployment of a transcatheter mitral valve prosthesis |
| US11678983B2 (en) | 2018-12-12 | 2023-06-20 | W. L. Gore & Associates, Inc. | Implantable component with socket |
| EP3905990A4 (en) * | 2019-01-03 | 2022-08-31 | Renovo Medsolutions, LLC | VENOUS VALVE PROSTHESIS |
| US11497601B2 (en) | 2019-03-01 | 2022-11-15 | W. L. Gore & Associates, Inc. | Telescoping prosthetic valve with retention element |
| CA3132873C (en) | 2019-03-08 | 2024-07-02 | Neovasc Tiara Inc | RECOVERABLE PROSTHESIS PLACEMENT SYSTEM |
| WO2020206012A1 (en) | 2019-04-01 | 2020-10-08 | Neovasc Tiara Inc. | Controllably deployable prosthetic valve |
| CN113924065A (zh) | 2019-04-10 | 2022-01-11 | 内奥瓦斯克迪亚拉公司 | 具有自然血流的假体瓣膜 |
| EP3952790A1 (en) | 2019-04-12 | 2022-02-16 | W.L. Gore & Associates, Inc. | Valve with multi-part frame and associated resilient bridging features |
| US11779742B2 (en) | 2019-05-20 | 2023-10-10 | Neovasc Tiara Inc. | Introducer with hemostasis mechanism |
| EP3986332A4 (en) | 2019-06-20 | 2023-07-19 | Neovasc Tiara Inc. | FLAT ARTIFICIAL MITRAL VALVE |
| EP4007545A1 (en) | 2019-08-01 | 2022-06-08 | W. L. Gore & Associates, Inc. | Transcatheter prosthetic valve with multi-part frame subcomponent transverse deformation resistance |
| AU2020324465A1 (en) | 2019-08-08 | 2022-02-24 | Edwards Lifesciences Corporation | Prosthetic valve with asymmetric leaflets |
| CN116036366B (zh) * | 2020-01-16 | 2024-10-18 | 四川大学 | 一种人工心脏瓣膜 |
| EP4225214B1 (en) * | 2020-10-07 | 2025-11-19 | St. Jude Medical, Cardiology Division, Inc. | Heat treating to improve synthetic leaflet motion and coaptation |
| CN116251238B (zh) * | 2023-02-28 | 2023-11-21 | 上海心纪元医疗科技有限公司 | 具有三层结构的仿生瓣膜瓣叶及其制造方法 |
Family Cites Families (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA962021A (en) | 1970-05-21 | 1975-02-04 | Robert W. Gore | Porous products and process therefor |
| US4340091A (en) | 1975-05-07 | 1982-07-20 | Albany International Corp. | Elastomeric sheet materials for heart valve and other prosthetic implants |
| US4339831A (en) | 1981-03-27 | 1982-07-20 | Medtronic, Inc. | Dynamic annulus heart valve and reconstruction ring |
| US4629459A (en) | 1983-12-28 | 1986-12-16 | Shiley Inc. | Alternate stent covering for tissue valves |
| US5071609A (en) | 1986-11-26 | 1991-12-10 | Baxter International Inc. | Process of manufacturing porous multi-expanded fluoropolymers |
| US4806382A (en) * | 1987-04-10 | 1989-02-21 | University Of Florida | Ocular implants and methods for their manufacture |
| US4816339A (en) * | 1987-04-28 | 1989-03-28 | Baxter International Inc. | Multi-layered poly(tetrafluoroethylene)/elastomer materials useful for in vivo implantation |
| US4955899A (en) | 1989-05-26 | 1990-09-11 | Impra, Inc. | Longitudinally compliant vascular graft |
| WO1997024083A1 (en) * | 1993-11-01 | 1997-07-10 | Cox James L | Method of replacing heart valves using flexible tubes |
| CA2165187C (en) | 1994-04-22 | 1999-09-14 | Carol E. Eberhardt | Stented bioprosthetic heart valve |
| JPH10503538A (ja) | 1994-07-27 | 1998-03-31 | ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティド | 高強度多孔質ポリテトラフルオロエチレンのシート材料 |
| AU688404B2 (en) | 1994-09-02 | 1998-03-12 | W.L. Gore & Associates, Inc. | Porous polytetrafluoroethylene compositions |
| US6428571B1 (en) | 1996-01-22 | 2002-08-06 | Scimed Life Systems, Inc. | Self-sealing PTFE vascular graft and manufacturing methods |
| AU727411B2 (en) | 1996-12-03 | 2000-12-14 | Atrium Medical Corporation | Multi-stage prosthesis |
| US6451396B1 (en) | 1998-02-13 | 2002-09-17 | Gore Enterprise Holdings, Inc. | Flexure endurant composite elastomer compositions |
| US7049380B1 (en) | 1999-01-19 | 2006-05-23 | Gore Enterprise Holdings, Inc. | Thermoplastic copolymer of tetrafluoroethylene and perfluoromethyl vinyl ether and medical devices employing the copolymer |
| DE69909331T2 (de) | 1999-05-10 | 2004-05-27 | THE SECRETARY OF STATE FOR DEFENCE Whitehall | Intelligenter poröser film oder intelligentes poröses material |
| US7628803B2 (en) | 2001-02-05 | 2009-12-08 | Cook Incorporated | Implantable vascular device |
| US20030055492A1 (en) | 1999-08-20 | 2003-03-20 | Shaolian Samuel M. | Transluminally implantable venous valve |
| US6440164B1 (en) | 1999-10-21 | 2002-08-27 | Scimed Life Systems, Inc. | Implantable prosthetic valve |
| US6652583B2 (en) | 2000-04-07 | 2003-11-25 | Rhode Island Hospital | Cardiac valve replacement |
| US7374571B2 (en) | 2001-03-23 | 2008-05-20 | Edwards Lifesciences Corporation | Rolled minimally-invasive heart valves and methods of manufacture |
| US6761733B2 (en) | 2001-04-11 | 2004-07-13 | Trivascular, Inc. | Delivery system and method for bifurcated endovascular graft |
| DE60205903T3 (de) | 2001-06-11 | 2014-10-16 | Boston Scientific Ltd. | Komposit eptfe/textil prothese |
| US6541589B1 (en) | 2001-10-15 | 2003-04-01 | Gore Enterprise Holdings, Inc. | Tetrafluoroethylene copolymer |
| US6776604B1 (en) | 2001-12-20 | 2004-08-17 | Trivascular, Inc. | Method and apparatus for shape forming endovascular graft material |
| WO2003092554A1 (en) | 2002-05-03 | 2003-11-13 | The General Hospital Corporation | Involuted endovascular valve and method of construction |
| US20030211264A1 (en) * | 2002-05-09 | 2003-11-13 | Farnsworth Ted Ray | Expanded polytetrafluoroethylene (ePTFE)-reinforced perfluoroelastomers (FFKM) |
| MXPA04011144A (es) * | 2002-05-10 | 2005-08-16 | Johnson & Johnson | Metodos para hacer un dispositivo medico que tiene una membrana tubular de pared delgada sobre un armazon estructural. |
| US7351256B2 (en) | 2002-05-10 | 2008-04-01 | Cordis Corporation | Frame based unidirectional flow prosthetic implant |
| US7789908B2 (en) * | 2002-06-25 | 2010-09-07 | Boston Scientific Scimed, Inc. | Elastomerically impregnated ePTFE to enhance stretch and recovery properties for vascular grafts and coverings |
| US20040024448A1 (en) * | 2002-08-05 | 2004-02-05 | Chang James W. | Thermoplastic fluoropolymer-coated medical devices |
| US7448122B1 (en) | 2003-10-31 | 2008-11-11 | Advanced Cardiovascular Systems, Inc. | Method of compressing a polymeric layer of an expandable medical device |
| US7261732B2 (en) * | 2003-12-22 | 2007-08-28 | Henri Justino | Stent mounted valve |
| US20110039690A1 (en) | 2004-02-02 | 2011-02-17 | Nanosys, Inc. | Porous substrates, articles, systems and compositions comprising nanofibers and methods of their use and production |
| MXPA06014480A (es) | 2004-06-09 | 2007-03-21 | Pathogen Removal And Diagnosti | Particulas incluidas en un substrato poroso para la remocion de analitos objetivo de una muestra. |
| GB0414099D0 (en) | 2004-06-23 | 2004-07-28 | Univ Glasgow | Biocompatible layered structures and methods for their manufacture |
| EP1796693A2 (en) | 2004-08-26 | 2007-06-20 | Chandrashekhar P. Pathak | Implantable tissue compositions and method |
| WO2006031436A1 (en) | 2004-09-10 | 2006-03-23 | Cook Incorporated | Prosthetic valve with pores |
| US8691543B2 (en) | 2009-11-25 | 2014-04-08 | Worcester Polytechnic Institute | Nanofibrous scaffold comprising immobilized cells |
| WO2006127756A2 (en) * | 2005-05-24 | 2006-11-30 | Edwards Lifesciences Corporation | Rapid deployment prosthetic heart valve |
| US8236051B2 (en) | 2005-06-27 | 2012-08-07 | The Cleveland Clinic Foundation | Apparatus for placement in the annulus of a tricuspid valve |
| US7531611B2 (en) | 2005-07-05 | 2009-05-12 | Gore Enterprise Holdings, Inc. | Copolymers of tetrafluoroethylene |
| CN101242889A (zh) * | 2005-07-18 | 2008-08-13 | 戈尔企业控股股份有限公司 | 多孔ptfe材料以及由其生产的制品 |
| US7306729B2 (en) | 2005-07-18 | 2007-12-11 | Gore Enterprise Holdings, Inc. | Porous PTFE materials and articles produced therefrom |
| WO2007016251A2 (en) | 2005-07-28 | 2007-02-08 | Cook Incorporated | Implantable thromboresistant valve |
| WO2007062320A2 (en) | 2005-11-18 | 2007-05-31 | Innovia, Llc | Trileaflet heart valve |
| EP2020958B1 (en) * | 2006-05-30 | 2012-05-30 | Cook Medical Technologies LLC | Artificial valve prosthesis |
| AU2007269117A1 (en) * | 2006-07-07 | 2008-01-10 | Endotronix, Inc. | Methods and systems for monitoring an endoprosthetic implant |
| US20080125711A1 (en) | 2006-08-07 | 2008-05-29 | Alpini Alfred A | Catheter balloons with integrated non-distensible seals |
| US20080220054A1 (en) | 2006-10-13 | 2008-09-11 | Shastri V Prasad | Modulation of drug release rate from electrospun fibers |
| WO2008046092A2 (en) | 2006-10-13 | 2008-04-17 | Creighton University | Implantable valve prosthesis |
| US20100190254A1 (en) | 2006-12-05 | 2010-07-29 | Nanyang Technological University | Three-dimensional porous hybrid scaffold and manufacture thereof |
| US8932619B2 (en) | 2007-06-27 | 2015-01-13 | Sofradim Production | Dural repair material |
| US20090187197A1 (en) | 2007-08-03 | 2009-07-23 | Roeber Peter J | Knit PTFE Articles and Mesh |
| WO2009038761A1 (en) | 2007-09-19 | 2009-03-26 | St. Jude Medical, Inc. | Fiber-reinforced synthetic sheets for prosthetic heart valve leaflets |
| US8637144B2 (en) | 2007-10-04 | 2014-01-28 | W. L. Gore & Associates, Inc. | Expandable TFE copolymers, method of making, and porous, expended articles thereof |
| US9402724B2 (en) | 2008-05-12 | 2016-08-02 | Mo-Sci Corporation | Dynamic bioactive nanofiber scaffolding |
| HUE047246T2 (hu) | 2008-06-06 | 2020-04-28 | Edwards Lifesciences Corp | Kis profilú transzkatéteres szívbillentyû |
| NL1036038C (en) | 2008-10-09 | 2010-04-14 | Univ Eindhoven Tech | Multilayer preform obtained by electro-spinning, method for producing a preform as well as use thereof. |
| US20150265744A1 (en) | 2008-10-09 | 2015-09-24 | Technische Universiteit Eindhoven | Multilayer preform obtained by electro-spinning, method for producing a preform as well as use thereof |
| US20160067374A1 (en) | 2009-01-16 | 2016-03-10 | Zeus Industrial Products, Inc. | Composite prosthetic devices |
| US9139669B2 (en) | 2009-03-24 | 2015-09-22 | W. L. Gore & Associates, Inc. | Expandable functional TFE copolymer fine powder, the expandable functional products obtained therefrom and reaction of the expanded products |
| TWI460007B (zh) | 2009-04-13 | 2014-11-11 | Entegris Inc | 多孔複合薄膜 |
| US10022222B2 (en) | 2009-10-06 | 2018-07-17 | Adam Groothuis | Systems and methods for treating lumenal valves |
| MX339572B (es) | 2009-11-27 | 2016-05-18 | Univ Nac Autónoma De México | Materiales compuestos de matriz polimerica con reforzantes de diferentes morfologias y sus procedimientos de sintesis. |
| US8795354B2 (en) * | 2010-03-05 | 2014-08-05 | Edwards Lifesciences Corporation | Low-profile heart valve and delivery system |
| EP2544624B1 (en) | 2010-03-11 | 2019-01-23 | Board Of Regents Of the University Of Texas System | Scaffold system to repair cardiovascular conditions |
| US9066997B2 (en) | 2010-06-02 | 2015-06-30 | The Regents Of The University Of Michigan | Scaffolds and methods of forming the same |
| US9801712B2 (en) | 2011-04-01 | 2017-10-31 | W. L. Gore & Associates, Inc. | Coherent single layer high strength synthetic polymer composites for prosthetic valves |
| US8945212B2 (en) | 2011-04-01 | 2015-02-03 | W. L. Gore & Associates, Inc. | Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom |
| US8961599B2 (en) | 2011-04-01 | 2015-02-24 | W. L. Gore & Associates, Inc. | Durable high strength polymer composite suitable for implant and articles produced therefrom |
| EP2522308B1 (de) | 2011-05-10 | 2015-02-25 | Biotronik AG | Mechanische Transkatheter-Herzklappenprothese |
| US8945209B2 (en) | 2011-05-20 | 2015-02-03 | Edwards Lifesciences Corporation | Encapsulated heart valve |
| CN104039271B (zh) | 2011-07-29 | 2016-09-07 | 卡内基梅隆大学 | 用于心脏重建手术的人工瓣膜化导管及其生产方法 |
| US9101469B2 (en) | 2012-12-19 | 2015-08-11 | W. L. Gore & Associates, Inc. | Prosthetic heart valve with leaflet shelving |
| US9144492B2 (en) | 2012-12-19 | 2015-09-29 | W. L. Gore & Associates, Inc. | Truncated leaflet for prosthetic heart valves, preformed valve |
| US9737398B2 (en) | 2012-12-19 | 2017-08-22 | W. L. Gore & Associates, Inc. | Prosthetic valves, frames and leaflets and methods thereof |
-
2011
- 2011-04-01 US US13/078,774 patent/US8961599B2/en not_active Expired - Fee Related
-
2012
- 2012-03-30 AU AU2012236318A patent/AU2012236318B2/en not_active Ceased
- 2012-03-30 KR KR1020137027469A patent/KR101994463B1/ko not_active Expired - Fee Related
- 2012-03-30 EP EP12764638.8A patent/EP2694123B1/en not_active Not-in-force
- 2012-03-30 WO PCT/US2012/031417 patent/WO2012135603A2/en not_active Ceased
- 2012-03-30 KR KR1020197018244A patent/KR102100082B1/ko not_active Expired - Fee Related
- 2012-03-30 CN CN201710014101.8A patent/CN106668949B/zh not_active Expired - Fee Related
- 2012-03-30 ES ES12764638.8T patent/ES2663094T3/es active Active
- 2012-03-30 CA CA3039324A patent/CA3039324A1/en not_active Abandoned
- 2012-03-30 RU RU2013148783/14A patent/RU2013148783A/ru not_active Application Discontinuation
- 2012-03-30 EP EP18150364.0A patent/EP3323439A1/en not_active Withdrawn
- 2012-03-30 CN CN201280016600.6A patent/CN103458934B/zh not_active Expired - Fee Related
- 2012-03-30 BR BR112013025114-0A patent/BR112013025114A2/pt not_active Application Discontinuation
- 2012-03-30 CA CA2830355A patent/CA2830355C/en not_active Expired - Fee Related
- 2012-03-30 JP JP2014502831A patent/JP6051202B2/ja not_active Expired - Fee Related
-
2015
- 2015-01-16 US US14/598,587 patent/US9770327B2/en not_active Expired - Fee Related
- 2015-05-28 US US14/724,640 patent/US9795475B2/en not_active Expired - Fee Related
-
2016
- 2016-11-28 JP JP2016230107A patent/JP6426680B2/ja not_active Expired - Fee Related
-
2018
- 2018-08-17 JP JP2018153634A patent/JP6725601B2/ja not_active Expired - Fee Related
- 2018-10-16 HK HK18113214.3A patent/HK1254143A1/en unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2663094T3 (es) | Compuesto polímero duradero de elevada resistencia mecánica adecuado para implante y artículos producidos a partir del mismo | |
| ES2701197T3 (es) | Compuestos polímeros duraderos de elevada resistencia mecánica adecuados para implante y artículos producidos a partir de los mismos | |
| US20200069418A1 (en) | Durable high strength polymer composites suitable for prosthetic valves | |
| ES2643173T3 (es) | Compuesto polimérico de alta resistencia multicapa duradero adecuado para implantes y artículos producidos a partir del mismo | |
| ES2860899T3 (es) | Compuestos de polímeros sintéticos de alta resistencia de capa única coherente para válvulas protésicas | |
| AU2020204354A1 (en) | Durable high strength polymer composite suitable for implant and articles produced therefrom | |
| HK40004911B (en) | Prosthetic heart valve comprising durable high strength polymer composites suitable for implant | |
| HK40004911A (en) | Prosthetic heart valve comprising durable high strength polymer composites suitable for implant | |
| HK1188574A (en) | Durable high strength polymer composite suitable for implant and articles produced therefrom | |
| HK1188574B (en) | Durable high strength polymer composite suitable for implant and articles produced therefrom | |
| HK1216087B (en) | Durable high strength polymer composites suitable for implant and articles produced therefrom |