HK1254143A1 - Durable high strength polymer composite suitable for implant and articles produced therefrom - Google Patents

Durable high strength polymer composite suitable for implant and articles produced therefrom Download PDF

Info

Publication number
HK1254143A1
HK1254143A1 HK18113214.3A HK18113214A HK1254143A1 HK 1254143 A1 HK1254143 A1 HK 1254143A1 HK 18113214 A HK18113214 A HK 18113214A HK 1254143 A1 HK1254143 A1 HK 1254143A1
Authority
HK
Hong Kong
Prior art keywords
leaflet
fluoropolymer
implantable article
layer
pores
Prior art date
Application number
HK18113214.3A
Other languages
English (en)
Chinese (zh)
Inventor
William C. Bruchman
Paul D. GASSLER
Cody L. Hartman
Peter J. Walsh
Charles F. White
Original Assignee
W.L. Gore & Associates Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by W.L. Gore & Associates Inc. filed Critical W.L. Gore & Associates Inc.
Publication of HK1254143A1 publication Critical patent/HK1254143A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A61F2/2415Manufacturing methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A61F2/2418Scaffolds therefor, e.g. support stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2469Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with resilient valve members, e.g. conical spiral
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2472Devices for testing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/48Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2475Venous valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0076Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof multilayered, e.g. laminated structures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/005Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements using adhesives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004Rounded shapes, e.g. with rounded corners
    • A61F2230/0006Rounded shapes, e.g. with rounded corners circular
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004Rounded shapes, e.g. with rounded corners
    • A61F2230/0013Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0028Shapes in the form of latin or greek characters
    • A61F2230/0054V-shaped
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/20Materials or treatment for tissue regeneration for reconstruction of the heart, e.g. heart valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/025Other specific inorganic materials not covered by A61L27/04 - A61L27/12
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Dispersion Chemistry (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Laminated Bodies (AREA)
HK18113214.3A 2011-04-01 2018-10-16 Durable high strength polymer composite suitable for implant and articles produced therefrom HK1254143A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/078,774 2011-04-01
US13/078,774 US8961599B2 (en) 2011-04-01 2011-04-01 Durable high strength polymer composite suitable for implant and articles produced therefrom

Publications (1)

Publication Number Publication Date
HK1254143A1 true HK1254143A1 (en) 2019-07-12

Family

ID=46928248

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18113214.3A HK1254143A1 (en) 2011-04-01 2018-10-16 Durable high strength polymer composite suitable for implant and articles produced therefrom

Country Status (12)

Country Link
US (3) US8961599B2 (enExample)
EP (2) EP2694123B1 (enExample)
JP (3) JP6051202B2 (enExample)
KR (2) KR101994463B1 (enExample)
CN (2) CN106668949B (enExample)
AU (1) AU2012236318B2 (enExample)
BR (1) BR112013025114A2 (enExample)
CA (2) CA3039324A1 (enExample)
ES (1) ES2663094T3 (enExample)
HK (1) HK1254143A1 (enExample)
RU (1) RU2013148783A (enExample)
WO (1) WO2012135603A2 (enExample)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2788453T3 (es) 2007-06-04 2020-10-21 St Jude Medical Llc Válvulas cardíacas protésicas
EP4223257B1 (en) * 2008-06-06 2024-06-12 Edwards Lifesciences Corporation Low profile transcatheter heart valve
US8579964B2 (en) 2010-05-05 2013-11-12 Neovasc Inc. Transcatheter mitral valve prosthesis
US8945212B2 (en) 2011-04-01 2015-02-03 W. L. Gore & Associates, Inc. Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom
US20130197631A1 (en) 2011-04-01 2013-08-01 W. L. Gore & Associates, Inc. Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom
US9744033B2 (en) 2011-04-01 2017-08-29 W.L. Gore & Associates, Inc. Elastomeric leaflet for prosthetic heart valves
US8961599B2 (en) 2011-04-01 2015-02-24 W. L. Gore & Associates, Inc. Durable high strength polymer composite suitable for implant and articles produced therefrom
US9554900B2 (en) * 2011-04-01 2017-01-31 W. L. Gore & Associates, Inc. Durable high strength polymer composites suitable for implant and articles produced therefrom
US9801712B2 (en) 2011-04-01 2017-10-31 W. L. Gore & Associates, Inc. Coherent single layer high strength synthetic polymer composites for prosthetic valves
US9308087B2 (en) 2011-04-28 2016-04-12 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
US9554897B2 (en) 2011-04-28 2017-01-31 Neovasc Tiara Inc. Methods and apparatus for engaging a valve prosthesis with tissue
US9554806B2 (en) 2011-09-16 2017-01-31 W. L. Gore & Associates, Inc. Occlusive devices
US9539360B2 (en) * 2011-10-07 2017-01-10 W. L. Gore & Associaes, Inc. Puncturable and resealable graft
DE102011117892A1 (de) * 2011-10-31 2013-05-02 Berlin Heart Gmbh Verbindungselement zum Montieren einer Blutpumpe oder einer Kanüle an einem Herzen
US9345573B2 (en) 2012-05-30 2016-05-24 Neovasc Tiara Inc. Methods and apparatus for loading a prosthesis onto a delivery system
US9283072B2 (en) 2012-07-25 2016-03-15 W. L. Gore & Associates, Inc. Everting transcatheter valve and methods
US10376360B2 (en) 2012-07-27 2019-08-13 W. L. Gore & Associates, Inc. Multi-frame prosthetic valve apparatus and methods
US10039638B2 (en) 2012-12-19 2018-08-07 W. L. Gore & Associates, Inc. Geometric prosthetic heart valves
US9968443B2 (en) 2012-12-19 2018-05-15 W. L. Gore & Associates, Inc. Vertical coaptation zone in a planar portion of prosthetic heart valve leaflet
US9101469B2 (en) 2012-12-19 2015-08-11 W. L. Gore & Associates, Inc. Prosthetic heart valve with leaflet shelving
US10321986B2 (en) 2012-12-19 2019-06-18 W. L. Gore & Associates, Inc. Multi-frame prosthetic heart valve
US10966820B2 (en) 2012-12-19 2021-04-06 W. L. Gore & Associates, Inc. Geometric control of bending character in prosthetic heart valve leaflets
US9737398B2 (en) 2012-12-19 2017-08-22 W. L. Gore & Associates, Inc. Prosthetic valves, frames and leaflets and methods thereof
US9398952B2 (en) * 2012-12-19 2016-07-26 W. L. Gore & Associates, Inc. Planar zone in prosthetic heart valve leaflet
US9144492B2 (en) 2012-12-19 2015-09-29 W. L. Gore & Associates, Inc. Truncated leaflet for prosthetic heart valves, preformed valve
WO2014143498A1 (en) * 2013-03-13 2014-09-18 W.L. Gore & Associates, Inc. Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom
AU2014242213A1 (en) * 2013-03-13 2015-08-20 W. L. Gore & Associates, Inc. Elastomeric leaflet for prosthetic heart valves
CA2900656C (en) * 2013-03-13 2021-05-11 W. L. Gore & Associates, Inc. Durable high strength polymer composites suitable for implant and articles produced therefrom
US9681951B2 (en) 2013-03-14 2017-06-20 Edwards Lifesciences Cardiaq Llc Prosthesis with outer skirt and anchors
US9572665B2 (en) 2013-04-04 2017-02-21 Neovasc Tiara Inc. Methods and apparatus for delivering a prosthetic valve to a beating heart
US11911258B2 (en) 2013-06-26 2024-02-27 W. L. Gore & Associates, Inc. Space filling devices
US9504565B2 (en) * 2013-12-06 2016-11-29 W. L. Gore & Associates, Inc. Asymmetric opening and closing prosthetic valve leaflet
AU2015305868B2 (en) 2014-08-18 2018-09-20 Edwards Lifesciences Corporation Frame with integral sewing cuff for prosthetic valves
US9827094B2 (en) 2014-09-15 2017-11-28 W. L. Gore & Associates, Inc. Prosthetic heart valve with retention elements
US10507101B2 (en) * 2014-10-13 2019-12-17 W. L. Gore & Associates, Inc. Valved conduit
US9937037B2 (en) 2014-12-18 2018-04-10 W. L. Gore & Associates, Inc. Prosthetic valved conduits with mechanically coupled leaflets
ES2860899T3 (es) * 2015-02-13 2021-10-05 Gore & Ass Compuestos de polímeros sintéticos de alta resistencia de capa única coherente para válvulas protésicas
US10232564B2 (en) * 2015-04-29 2019-03-19 Edwards Lifesciences Corporation Laminated sealing member for prosthetic heart valve
KR102140862B1 (ko) 2015-05-14 2020-08-03 더블유.엘. 고어 앤드 어소시에이트스, 인코포레이티드 심방이의 폐색을 위한 디바이스 및 방법
US10022223B2 (en) 2015-10-06 2018-07-17 W. L. Gore & Associates, Inc. Leaflet support devices and methods of making and using the same
US10631984B2 (en) 2015-12-15 2020-04-28 Neovasc Tiara Inc. Transseptal delivery system
US9968447B2 (en) * 2016-01-22 2018-05-15 Medtronic Vascular, Inc. Bioprosthetic tissue for use as a prosthetic valve leaflet and method of preparing
CA3007670C (en) 2016-01-29 2024-09-17 Neovasc Tiara Inc. PROSTHETIC VALVE PREVENTING OBSTRUCTION THAT WOULD PREVENT FLOW
AU2017361296B2 (en) 2016-11-21 2022-09-29 Neovasc Tiara Inc. Methods and systems for rapid retraction of a transcatheter heart valve delivery system
US11406533B2 (en) 2017-03-17 2022-08-09 W. L. Gore & Associates, Inc. Integrated aqueous shunt for glaucoma treatment
US10952842B2 (en) 2017-06-07 2021-03-23 W. L. Gore & Associates, Inc. Prosthetic valve with improved washout
US11224509B2 (en) * 2017-06-30 2022-01-18 Ohio State Innovation Foundation Prosthetic heart valve with tri-leaflet design for use in percutaneous valve replacement procedures
US12458491B2 (en) 2017-06-30 2025-11-04 Ohio State Innovation Foundation Methods to improve the durability of polymeric heart valves
WO2019036810A1 (en) 2017-08-25 2019-02-28 Neovasc Tiara Inc. TRANSCATHETER MITRAL VALVULE PROSTHESIS WITH SEQUENTIAL DEPLOYMENT
CN115568980A (zh) 2017-09-12 2023-01-06 W.L.戈尔及同仁股份有限公司 用于假体瓣膜的瓣叶框架附连件
JP7068444B2 (ja) 2017-09-27 2022-05-16 ダブリュ.エル.ゴア アンド アソシエイツ,インコーポレイティド 拡張可能なフレームを備えた人工弁、並びに関連するシステム及び方法
CN111163728B (zh) 2017-09-27 2022-04-29 W.L.戈尔及同仁股份有限公司 具有机械联接的瓣叶的假体瓣膜
CN116725739A (zh) 2017-10-13 2023-09-12 爱德华兹生命科学公司 叠套式假体瓣膜及递送系统
US11173023B2 (en) 2017-10-16 2021-11-16 W. L. Gore & Associates, Inc. Medical devices and anchors therefor
AU2018358725A1 (en) * 2017-10-31 2020-03-19 W. L. Gore & Associates, Inc. Synthetic prosthetic valve leaflet
CA3158944A1 (en) 2017-10-31 2019-05-09 W.L. Gore & Associates, Inc. Valved conduit
EP3703615B1 (en) 2017-10-31 2024-05-15 W. L. Gore & Associates, Inc. Transcatheter deployment systems and associated methods
CA3078606C (en) 2017-10-31 2023-09-05 W.L. Gore & Associates, Inc. Medical valve and leaflet promoting tissue ingrowth
US11123183B2 (en) 2017-10-31 2021-09-21 W. L. Gore & Associates, Inc. Prosthetic heart valve
US11154397B2 (en) 2017-10-31 2021-10-26 W. L. Gore & Associates, Inc. Jacket for surgical heart valve
US11166811B2 (en) 2018-03-02 2021-11-09 James Yashu Coe Transcatheter valve
WO2019224221A1 (en) 2018-05-21 2019-11-28 Aran Biomedical Teoranta Insertable medical devices with low profile composite coverings
US20210259831A1 (en) 2018-06-20 2021-08-26 W. L. Gore & Associates, Inc. Support structure for an implantable device with enhanced compressive stiffness region(s)
JP7720249B2 (ja) 2018-08-29 2025-08-07 ダブリュ.エル.ゴア アンド アソシエイツ,インコーポレイティド 薬物療法デリバリーシステム及び方法
CN109293961B (zh) * 2018-09-25 2021-08-13 湖南博隽生物医药有限公司 一种心脏瓣膜用聚合物材料及其制备方法
USD977642S1 (en) 2018-10-29 2023-02-07 W. L. Gore & Associates, Inc. Pulmonary valve conduit
USD926322S1 (en) 2018-11-07 2021-07-27 W. L. Gore & Associates, Inc. Heart valve cover
AU2019374743B2 (en) 2018-11-08 2022-03-03 Neovasc Tiara Inc. Ventricular deployment of a transcatheter mitral valve prosthesis
US11678983B2 (en) 2018-12-12 2023-06-20 W. L. Gore & Associates, Inc. Implantable component with socket
EP3905990A4 (en) * 2019-01-03 2022-08-31 Renovo Medsolutions, LLC VENOUS VALVE PROSTHESIS
US11497601B2 (en) 2019-03-01 2022-11-15 W. L. Gore & Associates, Inc. Telescoping prosthetic valve with retention element
EP3934591A4 (en) 2019-03-08 2022-11-23 Neovasc Tiara Inc. RETRIEVABLE PROSTHETIC RELEASE SYSTEM
EP3946163B1 (en) 2019-04-01 2025-08-20 Neovasc Tiara Inc. Controllably deployable prosthetic valve
AU2020271896B2 (en) 2019-04-10 2022-10-13 Neovasc Tiara Inc. Prosthetic valve with natural blood flow
WO2020210794A1 (en) 2019-04-12 2020-10-15 W. L. Gore & Associates, Inc. Valve with multi-part frame and associated resilient bridging features
CN114025813B (zh) 2019-05-20 2024-05-14 内奥瓦斯克迪亚拉公司 具有止血机构的引入器
AU2020295566B2 (en) 2019-06-20 2023-07-20 Neovasc Tiara Inc. Low profile prosthetic mitral valve
EP4007545A1 (en) 2019-08-01 2022-06-08 W. L. Gore & Associates, Inc. Transcatheter prosthetic valve with multi-part frame subcomponent transverse deformation resistance
WO2021026531A1 (en) 2019-08-08 2021-02-11 W. L. Gore & Associates, Inc Prosthetic valve with asymmetric leaflets
CN113117139B (zh) * 2020-01-16 2023-02-03 四川大学 一种加氢苯乙烯类热塑性弹性体在制备人工心脏瓣膜中的应用
WO2022076636A1 (en) * 2020-10-07 2022-04-14 St. Jude Medical, Cardiology Division, Inc. Heat treating to improve synthetic leaflet motion and coaptation
CN116251238B (zh) * 2023-02-28 2023-11-21 上海心纪元医疗科技有限公司 具有三层结构的仿生瓣膜瓣叶及其制造方法

Family Cites Families (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA962021A (en) 1970-05-21 1975-02-04 Robert W. Gore Porous products and process therefor
US4340091A (en) 1975-05-07 1982-07-20 Albany International Corp. Elastomeric sheet materials for heart valve and other prosthetic implants
US4339831A (en) 1981-03-27 1982-07-20 Medtronic, Inc. Dynamic annulus heart valve and reconstruction ring
US4629459A (en) 1983-12-28 1986-12-16 Shiley Inc. Alternate stent covering for tissue valves
US5071609A (en) 1986-11-26 1991-12-10 Baxter International Inc. Process of manufacturing porous multi-expanded fluoropolymers
US4806382A (en) * 1987-04-10 1989-02-21 University Of Florida Ocular implants and methods for their manufacture
US4816339A (en) * 1987-04-28 1989-03-28 Baxter International Inc. Multi-layered poly(tetrafluoroethylene)/elastomer materials useful for in vivo implantation
US4955899A (en) 1989-05-26 1990-09-11 Impra, Inc. Longitudinally compliant vascular graft
WO1997024083A1 (en) * 1993-11-01 1997-07-10 Cox James L Method of replacing heart valves using flexible tubes
EP0705081B1 (en) 1994-04-22 2001-10-17 Medtronic, Inc. Stented bioprosthetic heart valve
DE69419265T2 (de) 1994-07-27 2000-01-05 W.L. Gore & Associates, Inc. Höchfeste poröse folie aus ptfe
DE69428056T2 (de) 1994-09-02 2002-01-03 W.L. Gore & Associates, Inc. Poröse polytetrafluorethylen zusammensetzungen
US6428571B1 (en) 1996-01-22 2002-08-06 Scimed Life Systems, Inc. Self-sealing PTFE vascular graft and manufacturing methods
JP2002510985A (ja) 1996-12-03 2002-04-09 アトリウム メディカル コーポレーション 多層式プロテーゼ
US6451396B1 (en) 1998-02-13 2002-09-17 Gore Enterprise Holdings, Inc. Flexure endurant composite elastomer compositions
US7049380B1 (en) 1999-01-19 2006-05-23 Gore Enterprise Holdings, Inc. Thermoplastic copolymer of tetrafluoroethylene and perfluoromethyl vinyl ether and medical devices employing the copolymer
DE69909331T2 (de) 1999-05-10 2004-05-27 THE SECRETARY OF STATE FOR DEFENCE Whitehall Intelligenter poröser film oder intelligentes poröses material
US7628803B2 (en) 2001-02-05 2009-12-08 Cook Incorporated Implantable vascular device
US20030055492A1 (en) 1999-08-20 2003-03-20 Shaolian Samuel M. Transluminally implantable venous valve
US6440164B1 (en) 1999-10-21 2002-08-27 Scimed Life Systems, Inc. Implantable prosthetic valve
US6652583B2 (en) 2000-04-07 2003-11-25 Rhode Island Hospital Cardiac valve replacement
US7374571B2 (en) 2001-03-23 2008-05-20 Edwards Lifesciences Corporation Rolled minimally-invasive heart valves and methods of manufacture
US6761733B2 (en) 2001-04-11 2004-07-13 Trivascular, Inc. Delivery system and method for bifurcated endovascular graft
JP4401165B2 (ja) 2001-06-11 2010-01-20 ボストン サイエンティフィック リミテッド 複合ePTFE/繊維プロテーゼ
US6541589B1 (en) 2001-10-15 2003-04-01 Gore Enterprise Holdings, Inc. Tetrafluoroethylene copolymer
US6776604B1 (en) 2001-12-20 2004-08-17 Trivascular, Inc. Method and apparatus for shape forming endovascular graft material
WO2003092554A1 (en) 2002-05-03 2003-11-13 The General Hospital Corporation Involuted endovascular valve and method of construction
US20030211264A1 (en) * 2002-05-09 2003-11-13 Farnsworth Ted Ray Expanded polytetrafluoroethylene (ePTFE)-reinforced perfluoroelastomers (FFKM)
US7351256B2 (en) 2002-05-10 2008-04-01 Cordis Corporation Frame based unidirectional flow prosthetic implant
CA2485285A1 (en) * 2002-05-10 2003-11-20 Cordis Corporation Method of making a medical device having a thin wall tubular membrane over a structural frame
US7789908B2 (en) 2002-06-25 2010-09-07 Boston Scientific Scimed, Inc. Elastomerically impregnated ePTFE to enhance stretch and recovery properties for vascular grafts and coverings
US20040024448A1 (en) * 2002-08-05 2004-02-05 Chang James W. Thermoplastic fluoropolymer-coated medical devices
US7448122B1 (en) 2003-10-31 2008-11-11 Advanced Cardiovascular Systems, Inc. Method of compressing a polymeric layer of an expandable medical device
US7261732B2 (en) * 2003-12-22 2007-08-28 Henri Justino Stent mounted valve
US20110039690A1 (en) 2004-02-02 2011-02-17 Nanosys, Inc. Porous substrates, articles, systems and compositions comprising nanofibers and methods of their use and production
EP1766069B1 (en) 2004-06-09 2017-03-08 Pathogen Removal And Diagnostic Technologies Inc. Devices and methods for removing target agents from a sample
GB0414099D0 (en) 2004-06-23 2004-07-28 Univ Glasgow Biocompatible layered structures and methods for their manufacture
US7919112B2 (en) 2004-08-26 2011-04-05 Pathak Holdings, Llc Implantable tissue compositions and method
EP1807023A1 (en) 2004-09-10 2007-07-18 Cook Incorporated Prosthetic valve with pores
US8691543B2 (en) 2009-11-25 2014-04-08 Worcester Polytechnic Institute Nanofibrous scaffold comprising immobilized cells
US8500798B2 (en) 2005-05-24 2013-08-06 Edwards Lifesciences Corporation Rapid deployment prosthetic heart valve
US8236051B2 (en) 2005-06-27 2012-08-07 The Cleveland Clinic Foundation Apparatus for placement in the annulus of a tricuspid valve
US7531611B2 (en) 2005-07-05 2009-05-12 Gore Enterprise Holdings, Inc. Copolymers of tetrafluoroethylene
CN101242889A (zh) * 2005-07-18 2008-08-13 戈尔企业控股股份有限公司 多孔ptfe材料以及由其生产的制品
US7306729B2 (en) 2005-07-18 2007-12-11 Gore Enterprise Holdings, Inc. Porous PTFE materials and articles produced therefrom
WO2007016251A2 (en) 2005-07-28 2007-02-08 Cook Incorporated Implantable thromboresistant valve
WO2007062320A2 (en) 2005-11-18 2007-05-31 Innovia, Llc Trileaflet heart valve
CA2653913C (en) * 2006-05-30 2012-04-17 Cook Incorporated Artificial valve prosthesis
KR20090054427A (ko) * 2006-07-07 2009-05-29 안토니오 누에즈 관내 인공 삽입 임플란트를 모니터링하기 위한 방법 및 시스템
US20080125711A1 (en) 2006-08-07 2008-05-29 Alpini Alfred A Catheter balloons with integrated non-distensible seals
US20080220054A1 (en) 2006-10-13 2008-09-11 Shastri V Prasad Modulation of drug release rate from electrospun fibers
WO2008046092A2 (en) 2006-10-13 2008-04-17 Creighton University Implantable valve prosthesis
WO2008069759A1 (en) 2006-12-05 2008-06-12 Nanyang Technological University Manufacturing three-dimensional scaffolds using electrospinning at low temperatures
US8932619B2 (en) 2007-06-27 2015-01-13 Sofradim Production Dural repair material
US20090187197A1 (en) 2007-08-03 2009-07-23 Roeber Peter J Knit PTFE Articles and Mesh
US20100249922A1 (en) 2007-09-19 2010-09-30 St Jude Medical Inc. Fiber-reinforced synthetic sheets for prosthetic heart valve leaflets
US8637144B2 (en) 2007-10-04 2014-01-28 W. L. Gore & Associates, Inc. Expandable TFE copolymers, method of making, and porous, expended articles thereof
US9402724B2 (en) 2008-05-12 2016-08-02 Mo-Sci Corporation Dynamic bioactive nanofiber scaffolding
EP4223257B1 (en) 2008-06-06 2024-06-12 Edwards Lifesciences Corporation Low profile transcatheter heart valve
US20150265744A1 (en) 2008-10-09 2015-09-24 Technische Universiteit Eindhoven Multilayer preform obtained by electro-spinning, method for producing a preform as well as use thereof
NL1036038C (en) 2008-10-09 2010-04-14 Univ Eindhoven Tech Multilayer preform obtained by electro-spinning, method for producing a preform as well as use thereof.
US20160067374A1 (en) 2009-01-16 2016-03-10 Zeus Industrial Products, Inc. Composite prosthetic devices
US9139669B2 (en) 2009-03-24 2015-09-22 W. L. Gore & Associates, Inc. Expandable functional TFE copolymer fine powder, the expandable functional products obtained therefrom and reaction of the expanded products
WO2010120668A1 (en) 2009-04-13 2010-10-21 Entegris, Inc. Porous composite membrane
US10022222B2 (en) 2009-10-06 2018-07-17 Adam Groothuis Systems and methods for treating lumenal valves
MX339572B (es) 2009-11-27 2016-05-18 Univ Nac Autónoma De México Materiales compuestos de matriz polimerica con reforzantes de diferentes morfologias y sus procedimientos de sintesis.
US8795354B2 (en) * 2010-03-05 2014-08-05 Edwards Lifesciences Corporation Low-profile heart valve and delivery system
EP2544624B1 (en) 2010-03-11 2019-01-23 Board Of Regents Of the University Of Texas System Scaffold system to repair cardiovascular conditions
US9066997B2 (en) 2010-06-02 2015-06-30 The Regents Of The University Of Michigan Scaffolds and methods of forming the same
US9801712B2 (en) 2011-04-01 2017-10-31 W. L. Gore & Associates, Inc. Coherent single layer high strength synthetic polymer composites for prosthetic valves
US8961599B2 (en) 2011-04-01 2015-02-24 W. L. Gore & Associates, Inc. Durable high strength polymer composite suitable for implant and articles produced therefrom
US8945212B2 (en) 2011-04-01 2015-02-03 W. L. Gore & Associates, Inc. Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom
EP2522308B1 (de) 2011-05-10 2015-02-25 Biotronik AG Mechanische Transkatheter-Herzklappenprothese
US8945209B2 (en) 2011-05-20 2015-02-03 Edwards Lifesciences Corporation Encapsulated heart valve
AU2012290221B2 (en) 2011-07-29 2017-02-23 Carnegie Mellon University Artificial valved conduits for cardiac reconstructive procedures and methods for their production
US9144492B2 (en) 2012-12-19 2015-09-29 W. L. Gore & Associates, Inc. Truncated leaflet for prosthetic heart valves, preformed valve
US9101469B2 (en) 2012-12-19 2015-08-11 W. L. Gore & Associates, Inc. Prosthetic heart valve with leaflet shelving
US9737398B2 (en) 2012-12-19 2017-08-22 W. L. Gore & Associates, Inc. Prosthetic valves, frames and leaflets and methods thereof

Also Published As

Publication number Publication date
AU2012236318B2 (en) 2015-04-23
WO2012135603A2 (en) 2012-10-04
WO2012135603A3 (en) 2012-12-06
KR101994463B1 (ko) 2019-07-01
CN106668949A (zh) 2017-05-17
BR112013025114A2 (pt) 2021-01-05
US20150257875A1 (en) 2015-09-17
JP2017070771A (ja) 2017-04-13
JP6426680B2 (ja) 2018-11-21
EP2694123A4 (en) 2014-11-19
US20150144262A1 (en) 2015-05-28
JP2019000669A (ja) 2019-01-10
EP3323439A1 (en) 2018-05-23
AU2012236318A1 (en) 2013-09-19
JP6725601B2 (ja) 2020-07-22
CN106668949B (zh) 2021-01-01
KR20140016339A (ko) 2014-02-07
US20120253453A1 (en) 2012-10-04
CA3039324A1 (en) 2012-10-04
CN103458934A (zh) 2013-12-18
US9770327B2 (en) 2017-09-26
ES2663094T3 (es) 2018-04-11
KR102100082B1 (ko) 2020-04-13
US9795475B2 (en) 2017-10-24
RU2013148783A (ru) 2015-05-10
EP2694123B1 (en) 2018-01-24
KR20190092453A (ko) 2019-08-07
EP2694123A2 (en) 2014-02-12
US8961599B2 (en) 2015-02-24
CA2830355A1 (en) 2012-10-04
CN103458934B (zh) 2017-02-15
JP6051202B2 (ja) 2016-12-27
JP2014517720A (ja) 2014-07-24
CA2830355C (en) 2019-04-23

Similar Documents

Publication Publication Date Title
EP2694123B1 (en) Durable high strength polymer composite suitable for implant and articles produced therefrom
AU2018201999B2 (en) Durable high strength polymer composites suitable for implant and articles produced therefrom
US10470878B2 (en) Durable high strength polymer composites suitable for implant and articles produced therefrom
EP2713954B1 (en) Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom
AU2020204354A1 (en) Durable high strength polymer composite suitable for implant and articles produced therefrom
HK40004911B (en) Prosthetic heart valve comprising durable high strength polymer composites suitable for implant
HK40004911A (en) Prosthetic heart valve comprising durable high strength polymer composites suitable for implant
HK1188574B (en) Durable high strength polymer composite suitable for implant and articles produced therefrom
HK1188574A (en) Durable high strength polymer composite suitable for implant and articles produced therefrom
HK1216087B (en) Durable high strength polymer composites suitable for implant and articles produced therefrom
AU2016202250A1 (en) Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom
HK1196242A (en) Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom
HK1196242B (en) Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom