ES2632367T3 - Composiciones antibacterianas - Google Patents
Composiciones antibacterianas Download PDFInfo
- Publication number
- ES2632367T3 ES2632367T3 ES08806507.3T ES08806507T ES2632367T3 ES 2632367 T3 ES2632367 T3 ES 2632367T3 ES 08806507 T ES08806507 T ES 08806507T ES 2632367 T3 ES2632367 T3 ES 2632367T3
- Authority
- ES
- Spain
- Prior art keywords
- phage
- bacteria
- composition
- disinfectant
- phages
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 51
- 230000000844 anti-bacterial effect Effects 0.000 title description 2
- 241000894006 Bacteria Species 0.000 claims abstract description 87
- 230000009089 cytolysis Effects 0.000 claims abstract description 57
- 239000000645 desinfectant Substances 0.000 claims abstract description 25
- 238000000034 method Methods 0.000 claims abstract description 24
- 244000052769 pathogen Species 0.000 claims abstract description 11
- 230000001717 pathogenic effect Effects 0.000 claims abstract description 11
- 241000124008 Mammalia Species 0.000 claims description 8
- 241000191967 Staphylococcus aureus Species 0.000 claims description 7
- 210000003928 nasal cavity Anatomy 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 4
- 241000186781 Listeria Species 0.000 claims description 3
- 241000191940 Staphylococcus Species 0.000 claims description 3
- 239000006071 cream Substances 0.000 claims description 3
- 230000000699 topical effect Effects 0.000 claims description 3
- 241001453380 Burkholderia Species 0.000 claims description 2
- 241000589876 Campylobacter Species 0.000 claims description 2
- 241000193403 Clostridium Species 0.000 claims description 2
- 241000194033 Enterococcus Species 0.000 claims description 2
- 241000588722 Escherichia Species 0.000 claims description 2
- 241000589989 Helicobacter Species 0.000 claims description 2
- 241000588748 Klebsiella Species 0.000 claims description 2
- 239000004166 Lanolin Substances 0.000 claims description 2
- 241000589248 Legionella Species 0.000 claims description 2
- 208000007764 Legionnaires' Disease Diseases 0.000 claims description 2
- 241000186359 Mycobacterium Species 0.000 claims description 2
- 241000607142 Salmonella Species 0.000 claims description 2
- 241000607768 Shigella Species 0.000 claims description 2
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- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 4
- 239000004472 Lysine Substances 0.000 description 4
- 150000002669 lysines Chemical class 0.000 description 4
- 239000007787 solid Substances 0.000 description 4
- RJQXTJLFIWVMTO-TYNCELHUSA-N Methicillin Chemical compound COC1=CC=CC(OC)=C1C(=O)N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@@H]21 RJQXTJLFIWVMTO-TYNCELHUSA-N 0.000 description 3
- 238000013459 approach Methods 0.000 description 3
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- BPXVHIRIPLPOPT-UHFFFAOYSA-N 1,3,5-tris(2-hydroxyethyl)-1,3,5-triazinane-2,4,6-trione Chemical compound OCCN1C(=O)N(CCO)C(=O)N(CCO)C1=O BPXVHIRIPLPOPT-UHFFFAOYSA-N 0.000 description 2
- 244000025254 Cannabis sativa Species 0.000 description 2
- 241000193163 Clostridioides difficile Species 0.000 description 2
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- 108020000946 Bacterial DNA Proteins 0.000 description 1
- 241000700198 Cavia Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 241000192125 Firmicutes Species 0.000 description 1
- 102100036263 Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial Human genes 0.000 description 1
- 101001001786 Homo sapiens Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial Proteins 0.000 description 1
- 108090000604 Hydrolases Proteins 0.000 description 1
- 102000004157 Hydrolases Human genes 0.000 description 1
- 206010061598 Immunodeficiency Diseases 0.000 description 1
- 108091092195 Intron Proteins 0.000 description 1
- 241000123769 Listeria virus A511 Species 0.000 description 1
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 description 1
- 241001625930 Luria Species 0.000 description 1
- 239000006391 Luria-Bertani Medium Substances 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000037942 Methicillin-resistant Staphylococcus aureus infection Diseases 0.000 description 1
- MSFSPUZXLOGKHJ-UHFFFAOYSA-N Muraminsaeure Natural products OC(=O)C(C)OC1C(N)C(O)OC(CO)C1O MSFSPUZXLOGKHJ-UHFFFAOYSA-N 0.000 description 1
- 229930182555 Penicillin Natural products 0.000 description 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 1
- 108010087702 Penicillinase Proteins 0.000 description 1
- 108010013639 Peptidoglycan Proteins 0.000 description 1
- 241000229231 Phage E Species 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- JVWLUVNSQYXYBE-UHFFFAOYSA-N Ribitol Natural products OCC(C)C(O)C(O)CO JVWLUVNSQYXYBE-UHFFFAOYSA-N 0.000 description 1
- 206010070834 Sensitisation Diseases 0.000 description 1
- 241000239110 Staphylococcus virus K Species 0.000 description 1
- 206010061372 Streptococcal infection Diseases 0.000 description 1
- 239000004098 Tetracycline Substances 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 108020005202 Viral DNA Proteins 0.000 description 1
- 206010000269 abscess Diseases 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
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- -1 anionic polyol Chemical class 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
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- 210000000349 chromosome Anatomy 0.000 description 1
- 230000001332 colony forming effect Effects 0.000 description 1
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- 230000009977 dual effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 210000002889 endothelial cell Anatomy 0.000 description 1
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- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 238000005304 joining Methods 0.000 description 1
- 229910052744 lithium Inorganic materials 0.000 description 1
- 230000001320 lysogenic effect Effects 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
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- 210000003097 mucus Anatomy 0.000 description 1
- 239000002773 nucleotide Substances 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
- 229940049954 penicillin Drugs 0.000 description 1
- 230000008823 permeabilization Effects 0.000 description 1
- 238000001066 phage therapy Methods 0.000 description 1
- 229920001523 phosphate polymer Polymers 0.000 description 1
- 230000007505 plaque formation Effects 0.000 description 1
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- 230000006798 recombination Effects 0.000 description 1
- 238000005215 recombination Methods 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- HEBKCHPVOIAQTA-ZXFHETKHSA-N ribitol Chemical compound OC[C@H](O)[C@H](O)[C@H](O)CO HEBKCHPVOIAQTA-ZXFHETKHSA-N 0.000 description 1
- 238000011012 sanitization Methods 0.000 description 1
- 230000008313 sensitization Effects 0.000 description 1
- 238000013207 serial dilution Methods 0.000 description 1
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- 238000012360 testing method Methods 0.000 description 1
- 229960002180 tetracycline Drugs 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- 229940100611 topical cream Drugs 0.000 description 1
- 239000012049 topical pharmaceutical composition Substances 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/40—Viruses, e.g. bacteriophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/36—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing microorganisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10111—Myoviridae
- C12N2795/10132—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10211—Podoviridae
- C12N2795/10232—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Materials Engineering (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Agronomy & Crop Science (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Mycology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Communicable Diseases (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0719438 | 2007-10-04 | ||
| GB0719438A GB0719438D0 (en) | 2007-10-04 | 2007-10-04 | Anti-bacteria compositions |
| GB0800790A GB0800790D0 (en) | 2008-01-16 | 2008-01-16 | Anti-bacteria compositions |
| GB0800790 | 2008-01-16 | ||
| PCT/GB2008/003363 WO2009044163A2 (en) | 2007-10-04 | 2008-10-03 | Anti-bacteria compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2632367T3 true ES2632367T3 (es) | 2017-09-12 |
Family
ID=40526766
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES08806507.3T Active ES2632367T3 (es) | 2007-10-04 | 2008-10-03 | Composiciones antibacterianas |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20110182863A1 (https=) |
| EP (1) | EP2197284B1 (https=) |
| JP (2) | JP2011501740A (https=) |
| CN (1) | CN101835384B (https=) |
| AU (1) | AU2008306626B2 (https=) |
| CA (1) | CA2700646C (https=) |
| ES (1) | ES2632367T3 (https=) |
| WO (1) | WO2009044163A2 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010212280B2 (en) * | 2009-08-12 | 2015-09-24 | Buddhist Tzu Chi Medical Foundation | Phage of acinetobacter Baumannii |
| CN103458694A (zh) * | 2011-04-01 | 2013-12-18 | 通用电气公司 | 用于治理微生物诱导的腐蚀和环境损害及用于改进废水处理工艺的方法和组合物 |
| GB201119167D0 (en) | 2011-11-07 | 2011-12-21 | Novolytics Ltd | Novel bachteriophages |
| DE102013106455A1 (de) | 2013-06-20 | 2014-12-24 | Airbus Defence and Space GmbH | Verfahren zur Dekontamination von bakteriologischen Verunreinigungen |
| US10517908B2 (en) | 2015-08-13 | 2019-12-31 | Armata Pharmaceuticals, Inc. | Therapeutic bacteriophage compositions |
| EP3436041B1 (en) | 2016-03-31 | 2023-05-24 | Gojo Industries, Inc. | Sanitizer composition with probiotic/prebiotic active ingredient |
| AU2017240064B8 (en) | 2016-03-31 | 2021-11-11 | Gojo Industries, Inc. | Antimicrobial peptide stimulating sanitizing composition |
| WO2017173240A1 (en) | 2016-03-31 | 2017-10-05 | Gojo Industries, Inc. | Antimicrobial peptide stimulating cleansing composition |
| JP2020500860A (ja) | 2016-11-23 | 2020-01-16 | ゴジョ・インダストリーズ・インコーポレイテッド | プロバイオティック/プレバイオティックな有効成分を含む消毒薬組成物 |
| CN110719784A (zh) | 2017-02-13 | 2020-01-21 | 阿玛塔制药公司 | 治疗性噬菌体组合物 |
| CN112218659A (zh) * | 2018-01-02 | 2021-01-12 | 阿玛塔制药股份有限公司 | 用于治疗葡萄球菌感染的治疗性噬菌体组合物 |
| WO2019136108A1 (en) | 2018-01-02 | 2019-07-11 | Ampliphi Biosciences Corporation | Bacteriophage compositions for treating pseudomonas infections |
| FR3110599B1 (fr) * | 2020-05-19 | 2024-07-26 | Vetophage | Nouvelles souches de bacteriophages et leurs utilisations |
| EP3972620A1 (fr) * | 2019-05-21 | 2022-03-30 | Vetophage | Nouvelles souches de bactériophages et leurs utilisations |
| WO2024190909A1 (ja) | 2023-03-15 | 2024-09-19 | 国立感染症研究所長が代表する日本国 | 組換えファージ及びその調製方法 |
| EP4720263A1 (en) * | 2023-06-01 | 2026-04-08 | University of Florida Research Foundation, Incorporated | Phage therapy utilizing a unique cocktail of pseudomonas aeruginosa phages |
| CN118165942B (zh) * | 2024-03-22 | 2024-12-13 | 青岛润达生物科技有限公司 | 一株沙门氏菌噬菌体rdp-sa-22022及其连续化生产工艺和应用 |
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| US4957686A (en) * | 1990-02-06 | 1990-09-18 | Norris Alan H | Use of bacteriophages to inhibit dental caries |
| US5811093A (en) * | 1994-04-05 | 1998-09-22 | Exponential Biotherapies, Inc. | Bacteriophage genotypically modified to delay inactivations by the host defense system |
| WO1995027043A1 (en) * | 1994-04-05 | 1995-10-12 | Exponential Biotherapies, Inc. | Antibacterial therapy with genotypically modified bacteriophage |
| US6335012B1 (en) * | 1997-10-31 | 2002-01-01 | Vincent Fischetti | Use of bacterial phage associated lysing enzymes for treating bacterial infections of the mouth and teeth |
| ATE313341T1 (de) * | 2000-01-11 | 2006-01-15 | Intralytix Inc | Polymermischungen als bioabbaubare matrizen zur herstellung von biokompositen |
| US20040146490A1 (en) * | 2000-04-20 | 2004-07-29 | Mount Sinai Hospital | Antibacterial therapy for multi-drug resistant bacteria |
| DE60315636T2 (de) * | 2002-03-25 | 2008-05-08 | University Of Warwick, Coventry | Zur therapie und prophylaxe bakterieller infektionen geeignete bakteriophagen |
| NZ538098A (en) * | 2002-07-08 | 2007-01-26 | Ebi Food Safety B V | Lytic phage P100 ATCC deposit designation PTA-4383 to control listeria monocytogenes in foodstuffs and in food processing plants and treat animals infected |
| DE10342071B4 (de) * | 2003-09-10 | 2006-01-19 | Fleischmann, Wilhelm, Dr.med. | Vorrichtung und Verfahren zur Applikation von Wïrkstoffen an eine Wundoberfläche |
| US20060153811A1 (en) * | 2005-01-10 | 2006-07-13 | Jackson Lee E | Use of viruses and virus-resistant microorganisms for controlling microorganism populations |
| KR100781669B1 (ko) * | 2006-06-20 | 2007-12-03 | 주식회사 인트론바이오테크놀로지 | 황색포도상구균 특이적 사멸능을 갖는 박테리오파지 |
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| JP6053727B2 (ja) | 2016-12-27 |
| WO2009044163A3 (en) | 2010-02-11 |
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| US20110182863A1 (en) | 2011-07-28 |
| AU2008306626B2 (en) | 2013-05-09 |
| EP2197284B1 (en) | 2017-04-12 |
| JP2011501740A (ja) | 2011-01-13 |
| US20150216179A1 (en) | 2015-08-06 |
| CN101835384B (zh) | 2014-07-16 |
| EP2197284A2 (en) | 2010-06-23 |
| JP2015007087A (ja) | 2015-01-15 |
| CA2700646A1 (en) | 2009-04-09 |
| CA2700646C (en) | 2019-10-29 |
| AU2008306626A1 (en) | 2009-04-09 |
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