ES2630905T3 - Proteínas inmunitarias innatas como biomarcadores para lesiones del SNC - Google Patents

Proteínas inmunitarias innatas como biomarcadores para lesiones del SNC Download PDF

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Publication number
ES2630905T3
ES2630905T3 ES13746979.7T ES13746979T ES2630905T3 ES 2630905 T3 ES2630905 T3 ES 2630905T3 ES 13746979 T ES13746979 T ES 13746979T ES 2630905 T3 ES2630905 T3 ES 2630905T3
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ES
Spain
Prior art keywords
patient
protein
injury
inflamasome
level
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES13746979.7T
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English (en)
Spanish (es)
Inventor
Robert W. Keane
W. Dalton Dietrich
Juan Pablo De Rivero Vaccari
Stephanie ADAMCZAK
M. Ross Bullock
Allan LEVI
Michael Y. Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Miami
Original Assignee
University of Miami
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by University of Miami filed Critical University of Miami
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Publication of ES2630905T3 publication Critical patent/ES2630905T3/es
Active legal-status Critical Current
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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/70—Mechanisms involved in disease identification
    • G01N2800/7095—Inflammation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Neurology (AREA)
  • Pathology (AREA)
  • Neurosurgery (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ES13746979.7T 2012-02-06 2013-02-06 Proteínas inmunitarias innatas como biomarcadores para lesiones del SNC Active ES2630905T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261595254P 2012-02-06 2012-02-06
US201261595254P 2012-02-06
PCT/US2013/024941 WO2013119673A1 (en) 2012-02-06 2013-02-06 Innate immune proteins as biomarkers for cns injury

Publications (1)

Publication Number Publication Date
ES2630905T3 true ES2630905T3 (es) 2017-08-25

Family

ID=48947960

Family Applications (1)

Application Number Title Priority Date Filing Date
ES13746979.7T Active ES2630905T3 (es) 2012-02-06 2013-02-06 Proteínas inmunitarias innatas como biomarcadores para lesiones del SNC

Country Status (6)

Country Link
US (4) US20150185232A1 (cg-RX-API-DMAC10.html)
EP (1) EP2812697B1 (cg-RX-API-DMAC10.html)
JP (1) JP6170071B2 (cg-RX-API-DMAC10.html)
CA (1) CA2863417C (cg-RX-API-DMAC10.html)
ES (1) ES2630905T3 (cg-RX-API-DMAC10.html)
WO (1) WO2013119673A1 (cg-RX-API-DMAC10.html)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140302532A1 (en) 2011-04-12 2014-10-09 Quanterix Corporation Methods of determining a treatment protocol for and/or a prognosis of a patient's recovery from a brain injury
US10725054B2 (en) 2014-04-08 2020-07-28 University Of Florida Research Foundation, Incorporated Protein biomarkers for acute, subacute and chronic traumatic injuries of the central nervous system
US11840565B2 (en) 2016-12-29 2023-12-12 University Of Miami Methods and compositions for treating virus-associated inflammation
WO2018126009A1 (en) 2016-12-29 2018-07-05 University Of Miami Method for modulating inflammasome activity and inflammation in the lung
KR101910269B1 (ko) * 2017-02-24 2018-10-19 성균관대학교산학협력단 인간 뇌 조직 유래 신경줄기세포의 고효율 분리 방법
CN111356924A (zh) * 2017-09-20 2020-06-30 迈阿密大学 检测作为神经障碍生物标记的炎性体蛋白的方法
US12287343B2 (en) * 2018-04-10 2025-04-29 Quanterix Corporation Quantification of neurofilament light chain in physiological samples
EP3818081A4 (en) 2018-07-03 2022-06-22 University of Miami COMPOSITIONS AND METHODS FOR TREATING INFLAMMASOME-RELATED DISEASES OR DISORDERS
GB201815045D0 (en) 2018-09-14 2018-10-31 Univ Ulster Bispecific antibody targeting IL-1R1 and NLPR3
CN109406795A (zh) * 2018-11-20 2019-03-01 昆明医科大学 一种轻型脑外伤的血清分子诊断标记物及应用
CN113366318A (zh) * 2019-01-31 2021-09-07 日内瓦大学 创伤性脑损伤(tbi)的前瞻性标志物
US20210100909A1 (en) * 2019-10-07 2021-04-08 United States Government As Represented By The Department Of Veterans Affairs Polymeric Methylprednisolone Conjugates and Uses Thereof
US20230296626A1 (en) * 2020-04-27 2023-09-21 University Of Miami Compositions and methods for treating inflammasome related diseases or conditions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006508707A (ja) * 2002-09-04 2006-03-16 ワシントン・ユニバーシティ 中枢神経系損傷の治療法
US8685400B2 (en) * 2007-07-30 2014-04-01 University Of Miami Modulating inflammasome activity and inflammation in the central nervous system
CA2715248A1 (en) * 2008-02-04 2009-08-13 Banyan Biomarkers, Inc. Process to diagnose or treat brain injury
US8404752B2 (en) * 2008-07-18 2013-03-26 Oxygen Biotherapeutics, Inc. Method of treating traumatic brain injury
US20120177632A1 (en) * 2011-01-10 2012-07-12 Shinohara Mari L Methods of optimizing disease treatment

Also Published As

Publication number Publication date
JP6170071B2 (ja) 2017-07-26
CA2863417C (en) 2020-07-28
US20200363432A1 (en) 2020-11-19
WO2013119673A1 (en) 2013-08-15
US20170003303A1 (en) 2017-01-05
US20230349929A1 (en) 2023-11-02
JP2015508887A (ja) 2015-03-23
EP2812697B1 (en) 2017-03-22
CA2863417A1 (en) 2013-08-15
US20150185232A1 (en) 2015-07-02
US12560618B2 (en) 2026-02-24
EP2812697A4 (en) 2015-08-26
EP2812697A1 (en) 2014-12-17

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