ES2628841T3 - Proteínas de fusión npp1 - Google Patents
Proteínas de fusión npp1 Download PDFInfo
- Publication number
- ES2628841T3 ES2628841T3 ES11754231.6T ES11754231T ES2628841T3 ES 2628841 T3 ES2628841 T3 ES 2628841T3 ES 11754231 T ES11754231 T ES 11754231T ES 2628841 T3 ES2628841 T3 ES 2628841T3
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- fusion protein
- amino acid
- npp1
- target fraction
- acid residues
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| US8846603B2 (en) | 2010-03-12 | 2014-09-30 | Synageva Biopharma Corp. | NPP1 fusion proteins |
| NZ715014A (en) | 2010-09-09 | 2018-10-26 | Synageva Biopharma Corp | Use of lysosomal acid lipase for treating lysosomal acid lipase deficiency in patients |
| KR20140006037A (ko) | 2011-02-15 | 2014-01-15 | 시나게바 바이오파르마, 코포레이션 | 리소좀의 산 리파제 결핍을 치료하는 방법들 |
| AU2011362576B2 (en) * | 2011-03-11 | 2017-06-08 | Alexion Pharmaceuticals, Inc. | NPP1 fusion proteins |
| EP2956163B1 (en) | 2013-02-13 | 2024-11-27 | Yale University | Compositions for treating pathological calcification and ossification |
| JP6514190B2 (ja) * | 2013-05-06 | 2019-05-15 | バイオ−ラッド ラボラトリーズ インコーポレーティッド | 参照物質における不安定な被分析物の安定化 |
| BR112017012928A2 (pt) | 2014-12-19 | 2018-05-15 | Alexion Pharma Inc | uso de um ectonucleotídeo pirofosfatase fosfodiesterase (npp1); uso de uma composição farmacêutica; e uso de um snpp1 humano recombinante isolado, fragmento ou proteína de fusão deste |
| CA3176123A1 (en) * | 2015-05-19 | 2016-11-24 | Yale University | Compositions for treating pathological calcification conditions, and methods using same |
| JP2018537093A (ja) | 2015-11-20 | 2018-12-20 | イエール ユニバーシティ | 異所性石灰化障害を治療するための組成物およびそれを使用する方法 |
| US11364284B2 (en) | 2016-06-16 | 2022-06-21 | Inozyme Pharma, Inc. | Methods of treating myointimal proliferation |
| BR112019002355A2 (pt) | 2016-08-05 | 2019-07-16 | Yale University | composições e métodos para prevenção de acidente vascular cerebral em pacientes pediátricos com anemia falciforme |
| WO2019067502A1 (en) | 2017-09-27 | 2019-04-04 | Alexion Pharmaceuticals, Inc. | METHODS FOR IMPROVING CARDIOVASCULAR FUNCTION AND TREATING CARDIOVASCULAR DISEASE USING RECOMBINANT ECTO-NUCLEOTIDE PYROPHOSPHATASE / PHOSPHODIESTERASE |
| CN112930397B (zh) * | 2018-08-31 | 2025-05-09 | 耶鲁大学 | Enpp1多肽及其使用方法 |
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| US4935233A (en) | 1985-12-02 | 1990-06-19 | G. D. Searle And Company | Covalently linked polypeptide cell modulators |
| US6825396B2 (en) | 1996-06-12 | 2004-11-30 | Board Of Trustees Operating Michigan State University | Methods for tissue specific synthesis of protein in eggs of transgenic hens |
| CA2280957A1 (en) | 1997-02-14 | 1998-08-20 | Leslie Orgel | Methods and compositions for delivery of therapeutic agents to bone tissue employing conjugates of negatively charged peptide oligomers with therapeutic agents |
| US20040019923A1 (en) | 1997-10-16 | 2004-01-29 | Ivarie Robert D. | Exogenous proteins expressed in avians and their eggs |
| DE69842019D1 (de) | 1997-10-16 | 2011-01-05 | Synageva Biopharma Corp | Transgene vögel und proteinproduktion |
| ES2260852T3 (es) | 1997-11-07 | 2006-11-01 | Trillium Therapeutics Inc. | Metodos y composiciones para inmunomodulacion. |
| DE20121960U1 (de) | 2000-04-06 | 2004-01-15 | Epigenomics Ag | Nukleinsäuren für die Diagnose von mit Metastase assoziierten Krankheiten |
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-
2011
- 2011-03-11 US US13/583,973 patent/US8846603B2/en active Active
- 2011-03-11 WO PCT/US2011/028233 patent/WO2011113027A2/en not_active Ceased
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- 2011-09-15 JP JP2013557704A patent/JP5735665B2/ja active Active
- 2011-09-15 US US14/004,294 patent/US20140154774A1/en not_active Abandoned
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- 2011-09-15 TR TR2019/03573T patent/TR201903573T4/tr unknown
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2013
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2014
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2015
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2017
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2020
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|---|---|
| SG10202100341XA (en) | 2021-02-25 |
| US9540621B2 (en) | 2017-01-10 |
| US20170145393A1 (en) | 2017-05-25 |
| JP2015164427A (ja) | 2015-09-17 |
| CL2013002607A1 (es) | 2014-03-28 |
| ES2716526T3 (es) | 2019-06-13 |
| WO2011113027A3 (en) | 2012-03-01 |
| US20210301268A1 (en) | 2021-09-30 |
| US20140377859A1 (en) | 2014-12-25 |
| BR112013023010B1 (pt) | 2022-05-10 |
| US20230129977A1 (en) | 2023-04-27 |
| EP2545080A4 (en) | 2013-09-11 |
| US20130273021A1 (en) | 2013-10-17 |
| JP5735665B2 (ja) | 2015-06-17 |
| US20140154774A1 (en) | 2014-06-05 |
| EP2545080A2 (en) | 2013-01-16 |
| WO2011113027A2 (en) | 2011-09-15 |
| EP2545080B1 (en) | 2017-05-10 |
| US8846603B2 (en) | 2014-09-30 |
| JP6096826B2 (ja) | 2017-03-15 |
| BR112013023010A2 (pt) | 2018-07-03 |
| JP2014509851A (ja) | 2014-04-24 |
| TR201903573T4 (tr) | 2019-04-22 |
| US20150024460A1 (en) | 2015-01-22 |
| JP6484905B2 (ja) | 2019-03-20 |
| SG10201500208SA (en) | 2015-03-30 |
| JP2017137318A (ja) | 2017-08-10 |
| NZ615070A (en) | 2015-10-30 |
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