ES2627338T3 - Derivados de triazol útiles como antagonistas de receptores nicotínicos - Google Patents
Derivados de triazol útiles como antagonistas de receptores nicotínicos Download PDFInfo
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- ES2627338T3 ES2627338T3 ES12802484.1T ES12802484T ES2627338T3 ES 2627338 T3 ES2627338 T3 ES 2627338T3 ES 12802484 T ES12802484 T ES 12802484T ES 2627338 T3 ES2627338 T3 ES 2627338T3
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Landscapes
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2011/041866 WO2012177263A1 (en) | 2011-06-24 | 2011-06-24 | Compounds and methods of prophylaxis and treatment regarding nictonic receptor antagonists |
| WOPCT/US2011/041866 | 2011-06-24 | ||
| US201161501207P | 2011-06-25 | 2011-06-25 | |
| US201161501207P | 2011-06-25 | ||
| PCT/US2012/043880 WO2012178112A1 (en) | 2011-06-24 | 2012-06-22 | Organic compounds |
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| ES2627338T3 true ES2627338T3 (es) | 2017-07-27 |
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| ES12802484.1T Active ES2627338T3 (es) | 2011-06-24 | 2012-06-22 | Derivados de triazol útiles como antagonistas de receptores nicotínicos |
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| JP (1) | JP6087911B2 (enExample) |
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| WO2012177263A1 (en) * | 2011-06-24 | 2012-12-27 | Intra-Cellular Therapies, Inc. | Compounds and methods of prophylaxis and treatment regarding nictonic receptor antagonists |
| US11491150B2 (en) | 2017-05-22 | 2022-11-08 | Intra-Cellular Therapies, Inc. | Organic compounds |
| WO2019152680A1 (en) * | 2018-01-31 | 2019-08-08 | Flagship Pioneering Innovations V, Inc. | Methods and compositions for treating cancer using chrna6 inhibitors |
| WO2020146384A1 (en) | 2019-01-07 | 2020-07-16 | Intra-Cellular Therapies, Inc. | Organic compounds |
| WO2021008565A1 (zh) * | 2019-07-16 | 2021-01-21 | 清华大学 | 乙酰胆碱通路调节剂在治疗癌症中的用途 |
| EP4238970A1 (en) * | 2022-03-03 | 2023-09-06 | InterAx Biotech AG | Modulators of ackr3 and uses thereof |
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| US6953855B2 (en) * | 1998-12-11 | 2005-10-11 | Targacept, Inc. | 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof |
| PE20021019A1 (es) * | 2001-04-19 | 2002-11-13 | Upjohn Co | Grupos azabiciclicos sustituidos |
| ES2338539T3 (es) * | 2001-11-01 | 2010-05-10 | Icagen, Inc. | Pirazolamidas para uso en el tratamiento del dolor. |
| BR0315056A (pt) | 2002-11-01 | 2005-08-16 | Pharmacia & Upjohn Co Llc | Compostos tendo tanto atividade agonista nicotìnica de alfa7 quanto atividade antagonista de 5ht3 para o tratamento de doenças do sistema nervoso central |
| MXPA05007689A (es) * | 2003-01-22 | 2005-09-30 | Pharmacia & Upjohn Co Llc | Tratamiento de enfermedades con agonistas completos del receptor alfa-7 de nach. |
| US7135575B2 (en) * | 2003-03-03 | 2006-11-14 | Array Biopharma, Inc. | P38 inhibitors and methods of use thereof |
| JP2006525355A (ja) * | 2003-05-01 | 2006-11-09 | アボット・ラボラトリーズ | ナトリウムチャンネルモジュレーターとしてのピラゾール−アミドおよびスルホンアミド |
| US20040220170A1 (en) * | 2003-05-01 | 2004-11-04 | Atkinson Robert N. | Pyrazole-amides and sulfonamides as sodium channel modulators |
| EP1638944A1 (en) * | 2003-06-12 | 2006-03-29 | Eli Lilly And Company | Tachykinin receptor antagonists |
| WO2009112459A1 (en) | 2008-03-11 | 2009-09-17 | Neurosearch A/S | Novel 1,2,3-triazole derivatives useful as modulators of nicotinic acetylcholine receptors |
| US20100179186A1 (en) | 2008-10-10 | 2010-07-15 | University Of Kentucky Research Foundation | USE OF A NOVEL ALPHA-7 nAChR ANTAGONIST TO SUPPRESS PATHOGENIC SIGNAL TRANSDUCTION IN CANCER AND AIDS |
| WO2012177263A1 (en) | 2011-06-24 | 2012-12-27 | Intra-Cellular Therapies, Inc. | Compounds and methods of prophylaxis and treatment regarding nictonic receptor antagonists |
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| WO2012177263A1 (en) | 2012-12-27 |
| WO2012178112A1 (en) | 2012-12-27 |
| AU2012272646A1 (en) | 2014-02-20 |
| US9708294B2 (en) | 2017-07-18 |
| MX342322B (es) | 2016-09-23 |
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| US9469625B2 (en) | 2016-10-18 |
| IL230036A (en) | 2016-10-31 |
| US9452160B2 (en) | 2016-09-27 |
| JP6087911B2 (ja) | 2017-03-01 |
| AU2012272646B2 (en) | 2016-09-08 |
| CA2840047A1 (en) | 2012-12-27 |
| EP2723173B1 (en) | 2017-04-19 |
| US20140205596A1 (en) | 2014-07-24 |
| US20140205595A1 (en) | 2014-07-24 |
| CN103717069A (zh) | 2014-04-09 |
| KR20140036305A (ko) | 2014-03-25 |
| CN103717069B (zh) | 2018-06-05 |
| US9108949B2 (en) | 2015-08-18 |
| BR112013033306A2 (pt) | 2016-08-16 |
| RU2610094C2 (ru) | 2017-02-07 |
| JP2014517078A (ja) | 2014-07-17 |
| US20160008343A1 (en) | 2016-01-14 |
| EP2723173A1 (en) | 2014-04-30 |
| AU2012272680A1 (en) | 2014-02-20 |
| CA2840373A1 (en) | 2012-12-27 |
| EP2723173A4 (en) | 2015-02-18 |
| RU2014102191A (ru) | 2015-07-27 |
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