ES2624427T3 - Tratamiento de enfermedades y trastornos relacionados con la actividad de proteína 1 de tipo transducina beta (TBL 1), incluyendo neoplasia mieloproliferativa y leucemia mieloide crónica - Google Patents
Tratamiento de enfermedades y trastornos relacionados con la actividad de proteína 1 de tipo transducina beta (TBL 1), incluyendo neoplasia mieloproliferativa y leucemia mieloide crónica Download PDFInfo
- Publication number
- ES2624427T3 ES2624427T3 ES12845590.4T ES12845590T ES2624427T3 ES 2624427 T3 ES2624427 T3 ES 2624427T3 ES 12845590 T ES12845590 T ES 12845590T ES 2624427 T3 ES2624427 T3 ES 2624427T3
- Authority
- ES
- Spain
- Prior art keywords
- cells
- compound
- agent
- catenin
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161556245P | 2011-11-06 | 2011-11-06 | |
| US201161556245P | 2011-11-06 | ||
| PCT/US2012/063746 WO2013067547A1 (en) | 2011-11-06 | 2012-11-06 | METHODS FOR TREATMENT OF DISEASES AND DISORDERS RELATED TO TRANSDUCIN β-LIKE PROTEIN 1 (TBL 1) ACTIVITY, INCLUDING MYELOPROLIFERATIVE NEOPLASIA AND CHRONIC MYELOID LEUKEMIA |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2624427T3 true ES2624427T3 (es) | 2017-07-14 |
Family
ID=48192926
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES12845590.4T Active ES2624427T3 (es) | 2011-11-06 | 2012-11-06 | Tratamiento de enfermedades y trastornos relacionados con la actividad de proteína 1 de tipo transducina beta (TBL 1), incluyendo neoplasia mieloproliferativa y leucemia mieloide crónica |
Country Status (16)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9963475B2 (en) * | 2015-07-28 | 2018-05-08 | Beta Cat Pharmaceuticals, Inc. | Anthracene-9, 10-dione dioxime compound prodrugs and their uses |
| AU2016298280A1 (en) * | 2015-07-28 | 2018-02-22 | Beta Cat Pharmaceuticals, Inc. | Anthracene-9, 10-dione dioxime compounds prodrugs and their uses |
| CA3065318A1 (en) * | 2017-06-02 | 2018-12-06 | Iterion Therapeutics, Inc. | Methods for treatment of fibrotic diseases |
| WO2019099836A1 (en) * | 2017-11-16 | 2019-05-23 | Northwestern University | Inhaled formulation of a molecular inhibitor of wnt/beta-catenin signaling for treating interstitial lung diseases |
| WO2019229001A1 (en) * | 2018-05-30 | 2019-12-05 | Otto-Von-Guericke-Universität Magdeburg | Compounds for the treatment of jak2-v617f-associated cmn |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101486026B1 (ko) * | 2007-05-10 | 2015-01-22 | 도그우드 파마슈티컬스, 아이엔씨. | 플루오렌, 안트라센, 잔텐, 디벤조수베론 및 아크리딘의 유도체 및 이의 용도 |
| WO2008147713A1 (en) * | 2007-05-24 | 2008-12-04 | The Regents Of The University Of California | Wnt signaling inhibitors, and methods for making and using them |
| WO2010059142A1 (en) * | 2008-11-21 | 2010-05-27 | Avalon Pharmaceuticals | Anthraquinone dioximes and uses thereof |
| WO2011019648A1 (en) | 2009-08-10 | 2011-02-17 | Epitherix, Llc | Indazoles as wnt/b-catenin signaling pathway inhibitors and therapeutic uses thereof |
| WO2011025685A1 (en) * | 2009-08-24 | 2011-03-03 | Merck Sharp & Dohme Corp. | Jak inhibition blocks rna interference associated toxicities |
| AU2010302961A1 (en) | 2009-10-01 | 2012-04-19 | Csl Limited | Method of treatment of philadelphia chromosome positive leukaemia |
-
2012
- 2012-11-06 US US13/670,377 patent/US9238030B2/en active Active
- 2012-11-06 BR BR112014010584A patent/BR112014010584A2/pt not_active IP Right Cessation
- 2012-11-06 CN CN201280054386.3A patent/CN103917514B/zh active Active
- 2012-11-06 EA EA201490937A patent/EA027770B1/ru not_active IP Right Cessation
- 2012-11-06 SG SG11201402056XA patent/SG11201402056XA/en unknown
- 2012-11-06 CA CA2853491A patent/CA2853491C/en active Active
- 2012-11-06 MX MX2014005498A patent/MX354653B/es active IP Right Grant
- 2012-11-06 WO PCT/US2012/063746 patent/WO2013067547A1/en active Application Filing
- 2012-11-06 AU AU2012332111A patent/AU2012332111B2/en active Active
- 2012-11-06 JP JP2014540200A patent/JP6063472B2/ja active Active
- 2012-11-06 ES ES12845590.4T patent/ES2624427T3/es active Active
- 2012-11-06 EP EP12845590.4A patent/EP2773607B1/en active Active
- 2012-11-06 KR KR1020147015141A patent/KR102336767B1/ko not_active Application Discontinuation
-
2014
- 2014-04-24 ZA ZA2014/03003A patent/ZA201403003B/en unknown
- 2014-05-04 IL IL232452A patent/IL232452A/en active IP Right Grant
- 2014-11-26 HK HK14111950A patent/HK1198440A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2773607A4 (en) | 2015-03-11 |
| WO2013067547A1 (en) | 2013-05-10 |
| IL232452A (en) | 2017-01-31 |
| BR112014010584A2 (pt) | 2017-05-02 |
| EP2773607B1 (en) | 2017-03-29 |
| CA2853491C (en) | 2019-12-10 |
| CN103917514A (zh) | 2014-07-09 |
| MX354653B (es) | 2018-03-07 |
| CA2853491A1 (en) | 2013-05-10 |
| EP2773607A1 (en) | 2014-09-10 |
| US20130143920A1 (en) | 2013-06-06 |
| EA201490937A1 (ru) | 2014-08-29 |
| MX2014005498A (es) | 2016-05-05 |
| NZ624446A (en) | 2016-01-29 |
| HK1198440A1 (en) | 2015-04-24 |
| AU2012332111B2 (en) | 2016-11-17 |
| IL232452A0 (en) | 2014-06-30 |
| SG11201402056XA (en) | 2014-10-30 |
| US9238030B2 (en) | 2016-01-19 |
| EA027770B1 (ru) | 2017-08-31 |
| JP6063472B2 (ja) | 2017-01-18 |
| JP2014534229A (ja) | 2014-12-18 |
| AU2012332111A1 (en) | 2014-05-22 |
| KR102336767B1 (ko) | 2021-12-10 |
| ZA201403003B (en) | 2017-08-30 |
| KR20140089418A (ko) | 2014-07-14 |
| CN103917514B (zh) | 2016-11-16 |
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