ES2621324T3 - Equivalentes de piel secos e irradiados listos para su uso - Google Patents

Equivalentes de piel secos e irradiados listos para su uso Download PDF

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Publication number
ES2621324T3
ES2621324T3 ES09825325.5T ES09825325T ES2621324T3 ES 2621324 T3 ES2621324 T3 ES 2621324T3 ES 09825325 T ES09825325 T ES 09825325T ES 2621324 T3 ES2621324 T3 ES 2621324T3
Authority
ES
Spain
Prior art keywords
skin
equivalent
tissues
skin equivalent
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES09825325.5T
Other languages
English (en)
Spanish (es)
Inventor
Allen R. Comer
B. Lynn Allen-Hoffmann
Barry Steiglitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stratatech Corp
Original Assignee
Stratatech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stratatech Corp filed Critical Stratatech Corp
Application granted granted Critical
Publication of ES2621324T3 publication Critical patent/ES2621324T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3691Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/10Hair or skin implants
    • A61F2/105Skin implants, e.g. artificial skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3813Epithelial cells, e.g. keratinocytes, urothelial cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60Materials for use in artificial skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/40Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
ES09825325.5T 2008-11-04 2009-11-04 Equivalentes de piel secos e irradiados listos para su uso Active ES2621324T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US111153P 1998-12-07
US11115308P 2008-11-04 2008-11-04
PCT/US2009/063217 WO2010053948A1 (en) 2008-11-04 2009-11-04 Dried and irradiated skin equivalents for ready use

Publications (1)

Publication Number Publication Date
ES2621324T3 true ES2621324T3 (es) 2017-07-03

Family

ID=42153209

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09825325.5T Active ES2621324T3 (es) 2008-11-04 2009-11-04 Equivalentes de piel secos e irradiados listos para su uso

Country Status (10)

Country Link
US (5) US8580314B2 (https=)
EP (1) EP2352472B1 (https=)
JP (2) JP5632383B2 (https=)
CN (1) CN102271634B (https=)
AU (1) AU2009313656B2 (https=)
CA (1) CA2742595C (https=)
DK (1) DK2352472T3 (https=)
ES (1) ES2621324T3 (https=)
PT (1) PT2352472T (https=)
WO (1) WO2010053948A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009065005A1 (en) 2007-11-14 2009-05-22 Stratatech Corporation Cold storage of organotypically cultured skin equivalents for clinical applications
PT2352472T (pt) 2008-11-04 2017-04-11 Stratatech Corp Equivalentes de pele secos e irradiados prontos a utilizar
WO2010135655A2 (en) 2009-05-21 2010-11-25 Stratatech Corporation Human skin substitutes expressing il-12
CA3071928A1 (en) * 2013-03-13 2014-10-02 Stratatech Corporation Cryopreservation of viable human skin substitutes
KR101701396B1 (ko) 2014-10-28 2017-02-01 주식회사 엑티저 오디오 신호 처리 장치 및 방법
US20220287298A1 (en) * 2017-01-27 2022-09-15 Stratatech Corporation Tissue container systems
EP4034038A4 (en) * 2019-09-27 2023-11-01 Stratatech Corporation METHODS OF TREATING ACUTE WOUNDS AND IMPROVING RESULTS
WO2021231775A1 (en) * 2020-05-13 2021-11-18 Stratatech Copporation Viable bioengineered skin constructs

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4485096A (en) 1982-02-26 1984-11-27 Massachusetts Institute Of Technology Tissue-equivalent and method for preparation thereof
IL95429A (en) 1989-09-15 1997-09-30 Organogenesis Living tissue equivalents comprising hydrated collagen lattice and a collagen gel and their production
RU2135191C1 (ru) 1990-04-24 1999-08-27 Ортек Интернэшнл, Инк. Композиционный эквивалент живой кожи, способ его получения, тест-набор
US6585969B1 (en) 1991-11-20 2003-07-01 N. V. Innogenetics S.A. Non-viable keratinocyte cell composition or lysate for promoting wound healing
ES2149779T3 (es) 1991-11-20 2000-11-16 Innogenetics Nv Lisados derivados de queratinocitos para utilizacion como substancias cicatrizantes.
JPH10509610A (ja) * 1994-11-09 1998-09-22 クリ・ハークチ,ワリド 創傷修復用包帯およびそれらの保存法
US5693332C1 (en) 1995-08-11 2001-01-09 Univ California Human keratinocytes supported on a hydrophilic membrane and methods of using same to effect wound closure
JP3377354B2 (ja) * 1995-12-25 2003-02-17 株式会社メニコン 人工皮膚
US5968546A (en) 1997-05-16 1999-10-19 Baur; Marcus Keratinocyte culture from precursor cells
US5989837A (en) 1998-07-13 1999-11-23 Wisconsin Alumni Research Foundation Immortalized human keratinocyte cell line
DE60027724T2 (de) 1999-07-20 2007-03-01 DFB Pharmaceuticals, Inc., Fort Worth Verbesserte keratinozytenkultur und deren verwendungen
US6866686B2 (en) * 2000-01-28 2005-03-15 Cryolife, Inc. Tissue graft
US6974697B2 (en) 2001-03-02 2005-12-13 Stratech Corporation Skin substitutes with improved barrier function
EP1404809B1 (en) 2001-03-02 2013-12-11 Stratatech Corporation Improved skin substitutes and uses thereof
EP1549738B1 (en) 2002-04-30 2010-04-21 Stratatech Corporation Keratinocytes expressing exogenous angiogenic growth factors
EP1546392A4 (en) 2002-08-02 2006-05-24 Stratatech Corp DETECTION OF SPECIFIC DNA FROM SPECIES
US7993922B2 (en) 2002-10-18 2011-08-09 Reliance Life Sciences Pvt. Ltd. Three-dimensional tissue equivalent using macromass culture
EP1633858A4 (en) * 2003-05-30 2006-11-02 Stratatech Corp STORAGE OF ORGANS AT ROOM TEMPERATURE
CA2534349C (en) * 2003-08-01 2012-04-10 Stratatech Corporation Human skin equivalents expressing exogenous polypeptides
CA2758178C (en) 2003-08-01 2016-10-11 Stratatech Corporation Human skin equivalents expressing exogenous polypeptides
US8765169B2 (en) * 2004-02-13 2014-07-01 Smith & Nephew, Inc. Wound healing profile
WO2006055931A2 (en) 2004-11-18 2006-05-26 Stratatech Corporation Vectors for stable gene expression
JP4993752B2 (ja) 2005-03-01 2012-08-08 ストラタテック コーポレーション 外因性ポリペプチドを発現するヒト皮膚同等物
JP2008532550A (ja) 2005-03-17 2008-08-21 ストラタテック コーポレーション 純度が改良された代用皮膚
CN100400655C (zh) * 2005-12-02 2008-07-09 王平安 组织工程化细胞外基质的制备方法
WO2009065005A1 (en) 2007-11-14 2009-05-22 Stratatech Corporation Cold storage of organotypically cultured skin equivalents for clinical applications
PT2352472T (pt) 2008-11-04 2017-04-11 Stratatech Corp Equivalentes de pele secos e irradiados prontos a utilizar
WO2010135655A2 (en) 2009-05-21 2010-11-25 Stratatech Corporation Human skin substitutes expressing il-12

Also Published As

Publication number Publication date
CA2742595A1 (en) 2010-05-14
US9526811B2 (en) 2016-12-27
US8685463B2 (en) 2014-04-01
AU2009313656B2 (en) 2014-02-20
PT2352472T (pt) 2017-04-11
EP2352472A1 (en) 2011-08-10
US9867904B2 (en) 2018-01-16
EP2352472B1 (en) 2017-01-04
US20150196686A1 (en) 2015-07-16
CA2742595C (en) 2014-04-01
JP2012508064A (ja) 2012-04-05
AU2009313656A1 (en) 2010-05-14
CN102271634A (zh) 2011-12-07
JP2014221417A (ja) 2014-11-27
US20140288165A1 (en) 2014-09-25
WO2010053948A1 (en) 2010-05-14
US20170087276A1 (en) 2017-03-30
US8580314B2 (en) 2013-11-12
CN102271634B (zh) 2015-01-14
DK2352472T3 (en) 2017-04-10
EP2352472A4 (en) 2014-03-05
US20100119615A1 (en) 2010-05-13
JP5632383B2 (ja) 2014-11-26
US8992997B2 (en) 2015-03-31
US20140067064A1 (en) 2014-03-06

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