ES2621324T3 - Equivalentes de piel secos e irradiados listos para su uso - Google Patents

Equivalentes de piel secos e irradiados listos para su uso Download PDF

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Publication number
ES2621324T3
ES2621324T3 ES09825325.5T ES09825325T ES2621324T3 ES 2621324 T3 ES2621324 T3 ES 2621324T3 ES 09825325 T ES09825325 T ES 09825325T ES 2621324 T3 ES2621324 T3 ES 2621324T3
Authority
ES
Spain
Prior art keywords
skin
equivalent
tissues
skin equivalent
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES09825325.5T
Other languages
English (en)
Spanish (es)
Inventor
Allen R. Comer
B. Lynn Allen-Hoffmann
Barry Steiglitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stratatech Corp
Original Assignee
Stratatech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stratatech Corp filed Critical Stratatech Corp
Application granted granted Critical
Publication of ES2621324T3 publication Critical patent/ES2621324T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/10—Hair or skin implants
    • A61F2/105—Skin implants, e.g. artificial skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
ES09825325.5T 2008-11-04 2009-11-04 Equivalentes de piel secos e irradiados listos para su uso Active ES2621324T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11115308P 2008-11-04 2008-11-04
US111153P 2008-11-04
PCT/US2009/063217 WO2010053948A1 (en) 2008-11-04 2009-11-04 Dried and irradiated skin equivalents for ready use

Publications (1)

Publication Number Publication Date
ES2621324T3 true ES2621324T3 (es) 2017-07-03

Family

ID=42153209

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09825325.5T Active ES2621324T3 (es) 2008-11-04 2009-11-04 Equivalentes de piel secos e irradiados listos para su uso

Country Status (10)

Country Link
US (5) US8580314B2 (enExample)
EP (1) EP2352472B1 (enExample)
JP (2) JP5632383B2 (enExample)
CN (1) CN102271634B (enExample)
AU (1) AU2009313656B2 (enExample)
CA (1) CA2742595C (enExample)
DK (1) DK2352472T3 (enExample)
ES (1) ES2621324T3 (enExample)
PT (1) PT2352472T (enExample)
WO (1) WO2010053948A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090145087A1 (en) 2007-11-14 2009-06-11 Stratatech Corporation Cold storage of organotypically cultured skin equivalents for clinical applications
JP5632383B2 (ja) 2008-11-04 2014-11-26 ストラタテック コーポレーション 即時使用のための乾燥され、放射線照射された皮膚同等物
US20100330046A1 (en) * 2009-05-21 2010-12-30 Stratatech Corporation Human skin substitutes expressing il-12
EP3470018B1 (en) * 2013-03-13 2021-07-28 Stratatech Corporation Cryopreservation of viable human skin substitutes
KR101701396B1 (ko) 2014-10-28 2017-02-01 주식회사 엑티저 오디오 신호 처리 장치 및 방법
US20220287298A1 (en) * 2017-01-27 2022-09-15 Stratatech Corporation Tissue container systems
JP2022549688A (ja) * 2019-09-27 2022-11-28 ストラタテック コーポレーション 急性創傷を治療し、転帰を改善するための方法
IL297372A (en) * 2020-05-13 2022-12-01 Stratatech Corp Sustainable bioengineered skin constructs

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4485096A (en) * 1982-02-26 1984-11-27 Massachusetts Institute Of Technology Tissue-equivalent and method for preparation thereof
IL95429A (en) * 1989-09-15 1997-09-30 Organogenesis Living tissue equivalents comprising hydrated collagen lattice and a collagen gel and their production
CA2080693C (en) * 1990-04-24 2001-11-27 Mark Eisenberg Composite living skin equivalents
US6585969B1 (en) * 1991-11-20 2003-07-01 N. V. Innogenetics S.A. Non-viable keratinocyte cell composition or lysate for promoting wound healing
EP0970701B1 (en) * 1991-11-20 2005-10-26 Innogenetics N.V. Pellets derived from keratinocytes for use as wound healing substances
AU4106796A (en) * 1994-11-09 1996-06-06 Federico Castro Munozledo Wound repair dressings and methods for their preservation
US5693332C1 (en) * 1995-08-11 2001-01-09 Univ California Human keratinocytes supported on a hydrophilic membrane and methods of using same to effect wound closure
JP3377354B2 (ja) * 1995-12-25 2003-02-17 株式会社メニコン 人工皮膚
US5968546A (en) * 1997-05-16 1999-10-19 Baur; Marcus Keratinocyte culture from precursor cells
US5989837A (en) * 1998-07-13 1999-11-23 Wisconsin Alumni Research Foundation Immortalized human keratinocyte cell line
EP1198557B1 (en) * 1999-07-20 2006-05-03 DFB Pharmaceuticals, Inc. Improved keratinocyte culture and uses thereof
US6866686B2 (en) 2000-01-28 2005-03-15 Cryolife, Inc. Tissue graft
US6974697B2 (en) * 2001-03-02 2005-12-13 Stratech Corporation Skin substitutes with improved barrier function
WO2002070729A2 (en) * 2001-03-02 2002-09-12 Stratatech Corporation Improved skin substitutes and uses thereof
DE60332256D1 (de) * 2002-04-30 2010-06-02 Stratatech Corp Exogene angiogene wachstumsfaktoren exprimierende keratinozyten
WO2004013606A2 (en) 2002-08-02 2004-02-12 Stratatech Corporation Species specific dna detection
US7993922B2 (en) * 2002-10-18 2011-08-09 Reliance Life Sciences Pvt. Ltd. Three-dimensional tissue equivalent using macromass culture
JP2006526413A (ja) * 2003-05-30 2006-11-24 ストラタテック コーポレーション 臓器の室温保存法
EP3100611B1 (en) * 2003-08-01 2018-09-12 Stratatech Corporation Human skin equivalents expressing exogenous polypeptides
CA2758178C (en) 2003-08-01 2016-10-11 Stratatech Corporation Human skin equivalents expressing exogenous polypeptides
AU2005215211B2 (en) * 2004-02-13 2011-11-03 Smith & Nephew Orthopaedics Ag Wound healing profile
WO2006055931A2 (en) 2004-11-18 2006-05-26 Stratatech Corporation Vectors for stable gene expression
CA2600177C (en) 2005-03-01 2011-06-14 Stratatech Corporation Human skin equivalents expressing exogenous polypeptides
WO2006101834A1 (en) 2005-03-17 2006-09-28 Stratatech Corporation Skin substitutes with improved purity
CN100400655C (zh) 2005-12-02 2008-07-09 王平安 组织工程化细胞外基质的制备方法
US20090145087A1 (en) * 2007-11-14 2009-06-11 Stratatech Corporation Cold storage of organotypically cultured skin equivalents for clinical applications
JP5632383B2 (ja) 2008-11-04 2014-11-26 ストラタテック コーポレーション 即時使用のための乾燥され、放射線照射された皮膚同等物
US20100330046A1 (en) * 2009-05-21 2010-12-30 Stratatech Corporation Human skin substitutes expressing il-12

Also Published As

Publication number Publication date
US20170087276A1 (en) 2017-03-30
US9867904B2 (en) 2018-01-16
JP5632383B2 (ja) 2014-11-26
US20150196686A1 (en) 2015-07-16
PT2352472T (pt) 2017-04-11
JP2014221417A (ja) 2014-11-27
JP2012508064A (ja) 2012-04-05
CA2742595C (en) 2014-04-01
CA2742595A1 (en) 2010-05-14
CN102271634A (zh) 2011-12-07
AU2009313656B2 (en) 2014-02-20
CN102271634B (zh) 2015-01-14
US20100119615A1 (en) 2010-05-13
AU2009313656A1 (en) 2010-05-14
EP2352472A4 (en) 2014-03-05
DK2352472T3 (en) 2017-04-10
EP2352472B1 (en) 2017-01-04
US8580314B2 (en) 2013-11-12
US8685463B2 (en) 2014-04-01
US20140067064A1 (en) 2014-03-06
WO2010053948A1 (en) 2010-05-14
US9526811B2 (en) 2016-12-27
US20140288165A1 (en) 2014-09-25
US8992997B2 (en) 2015-03-31
EP2352472A1 (en) 2011-08-10

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