ES2619959T3 - Canal de mezclado para un dispositivo de inhalación y dispositivo de inhalación - Google Patents
Canal de mezclado para un dispositivo de inhalación y dispositivo de inhalación Download PDFInfo
- Publication number
- ES2619959T3 ES2619959T3 ES13714561.1T ES13714561T ES2619959T3 ES 2619959 T3 ES2619959 T3 ES 2619959T3 ES 13714561 T ES13714561 T ES 13714561T ES 2619959 T3 ES2619959 T3 ES 2619959T3
- Authority
- ES
- Spain
- Prior art keywords
- mixing channel
- channel
- nebulizer
- injection zone
- mixing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000006199 nebulizer Substances 0.000 claims abstract description 121
- 238000002347 injection Methods 0.000 claims abstract description 81
- 239000007924 injection Substances 0.000 claims abstract description 81
- 238000011144 upstream manufacturing Methods 0.000 claims abstract description 34
- 230000007423 decrease Effects 0.000 claims abstract description 18
- 239000000443 aerosol Substances 0.000 claims description 74
- 239000007788 liquid Substances 0.000 claims description 27
- 230000007704 transition Effects 0.000 claims description 25
- 239000012528 membrane Substances 0.000 claims description 22
- 229940079593 drug Drugs 0.000 claims description 15
- 239000003814 drug Substances 0.000 claims description 15
- 239000000463 material Substances 0.000 claims description 5
- 239000000560 biocompatible material Substances 0.000 claims description 3
- 230000002209 hydrophobic effect Effects 0.000 claims description 2
- URLKBWYHVLBVBO-UHFFFAOYSA-N Para-Xylene Chemical group CC1=CC=C(C)C=C1 URLKBWYHVLBVBO-UHFFFAOYSA-N 0.000 claims 2
- 239000003570 air Substances 0.000 description 65
- 238000000151 deposition Methods 0.000 description 16
- 230000008021 deposition Effects 0.000 description 15
- 230000003247 decreasing effect Effects 0.000 description 10
- 239000000203 mixture Substances 0.000 description 10
- 210000004072 lung Anatomy 0.000 description 9
- 238000004581 coalescence Methods 0.000 description 8
- 239000002245 particle Substances 0.000 description 7
- 239000007921 spray Substances 0.000 description 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 5
- 238000009472 formulation Methods 0.000 description 5
- 239000012669 liquid formulation Substances 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 239000003595 mist Substances 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 238000007789 sealing Methods 0.000 description 5
- 238000013459 approach Methods 0.000 description 4
- 230000008859 change Effects 0.000 description 4
- 238000009826 distribution Methods 0.000 description 4
- 239000012530 fluid Substances 0.000 description 4
- 239000012634 fragment Substances 0.000 description 4
- 230000000144 pharmacologic effect Effects 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 230000001133 acceleration Effects 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 238000003780 insertion Methods 0.000 description 3
- 230000037431 insertion Effects 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- 238000004088 simulation Methods 0.000 description 3
- LERNTVKEWCAPOY-VOGVJGKGSA-N C[N+]1(C)[C@H]2C[C@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)C(O)(c1cccs1)c1cccs1 Chemical compound C[N+]1(C)[C@H]2C[C@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)C(O)(c1cccs1)c1cccs1 LERNTVKEWCAPOY-VOGVJGKGSA-N 0.000 description 2
- 238000012387 aerosolization Methods 0.000 description 2
- 239000012867 bioactive agent Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- 230000002452 interceptive effect Effects 0.000 description 2
- 238000000465 moulding Methods 0.000 description 2
- 239000003380 propellant Substances 0.000 description 2
- 230000029058 respiratory gaseous exchange Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 229960000257 tiotropium bromide Drugs 0.000 description 2
- AWYMFBJJKFTCFO-UHFFFAOYSA-N C(C1)C2C1CCC2 Chemical compound C(C1)C2C1CCC2 AWYMFBJJKFTCFO-UHFFFAOYSA-N 0.000 description 1
- 206010016654 Fibrosis Diseases 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 239000012080 ambient air Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 229940124446 critical care medicine Drugs 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 230000004761 fibrosis Effects 0.000 description 1
- 239000008240 homogeneous mixture Substances 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 235000010746 mayonnaise Nutrition 0.000 description 1
- 239000008268 mayonnaise Substances 0.000 description 1
- 229940071648 metered dose inhaler Drugs 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- -1 poly (p-xylylene) Polymers 0.000 description 1
- 229920000052 poly(p-xylylene) Polymers 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
- A61M11/003—Particle size control by passing the aerosol trough sieves or filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/005—Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0086—Inhalation chambers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/06—Inhaling appliances shaped like cigars, cigarettes or pipes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/06—Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/10—Trunk
- A61M2210/1025—Respiratory system
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Nozzles (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12158852 | 2012-03-09 | ||
| EP12158852 | 2012-03-09 | ||
| EP12190139.1A EP2724741B1 (en) | 2012-10-26 | 2012-10-26 | Inhalation device for use in aerosol therapy |
| EP12190139 | 2012-10-26 | ||
| PCT/EP2013/054705 WO2013132056A1 (en) | 2012-03-09 | 2013-03-08 | Mixing channel for an inhalation device and inhalation device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2619959T3 true ES2619959T3 (es) | 2017-06-27 |
Family
ID=49115967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES13714561.1T Active ES2619959T3 (es) | 2012-03-09 | 2013-03-08 | Canal de mezclado para un dispositivo de inhalación y dispositivo de inhalación |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US10857310B2 (enExample) |
| EP (2) | EP3146990B1 (enExample) |
| JP (2) | JP6174056B2 (enExample) |
| KR (1) | KR101903028B1 (enExample) |
| CN (2) | CN107929894B (enExample) |
| AU (1) | AU2013229447B2 (enExample) |
| CA (2) | CA2984393C (enExample) |
| DK (1) | DK2846859T3 (enExample) |
| ES (1) | ES2619959T3 (enExample) |
| HU (1) | HUE033664T2 (enExample) |
| IN (1) | IN2014DN08290A (enExample) |
| NZ (1) | NZ628562A (enExample) |
| PL (1) | PL2846859T3 (enExample) |
| PT (1) | PT2846859T (enExample) |
| RU (1) | RU2618917C2 (enExample) |
| SG (1) | SG11201405061VA (enExample) |
| SI (1) | SI2846859T1 (enExample) |
| WO (1) | WO2013132056A1 (enExample) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12329902B2 (en) | 2013-08-22 | 2025-06-17 | Sipnose Ltd. | Drug delivery devices and methods for administering substances to a body cavity by heterogenous aerosolization |
| US11278682B2 (en) | 2014-11-09 | 2022-03-22 | Sipnose Ltd. | Device and method for aerosolized delivery of substance to a natural orifice of the body |
| DE202013105715U1 (de) | 2013-08-22 | 2014-02-19 | Sipnose Ltd. | Vorrichtung zur Abgabe einer vorbestimmten Menge einer Substanz an eine natürliche Öffnung des Körpers |
| US11992604B2 (en) | 2014-11-09 | 2024-05-28 | Sipnose Ltd. | Devices and methods for delivering a substance to a body cavity |
| US12491325B2 (en) | 2013-08-22 | 2025-12-09 | Aptargroup, Inc. | Drug delivery devices and methods for administering substances to a body cavity by heterogenous aerosolization for treatment of binge-eating disorders and/or obesity |
| US11116914B2 (en) * | 2014-11-09 | 2021-09-14 | Sipnose Ltd. | Device and method for aerosolized delivering of substance to a natural orifice of the body |
| US12594388B2 (en) | 2013-08-22 | 2026-04-07 | Aptargroup, Inc. | Device to deliver a predetermined amount of a substance to a natural orifice of the body |
| US11471618B2 (en) | 2014-11-09 | 2022-10-18 | Sipnose Ltd. | Adjustable dosing delivery and multi sectioned drug compartment |
| US11123513B2 (en) | 2014-03-05 | 2021-09-21 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Humidifier for humidifying an aerosol |
| AU2015329935B2 (en) * | 2014-10-10 | 2019-09-19 | Ablynx N.V. | Inhalation device for use in aerosol therapy of respiratory diseases |
| CA2963037A1 (en) | 2014-10-10 | 2016-04-14 | Vectura Gmbh | Treatment of rsv infection |
| US20160325055A1 (en) * | 2015-05-08 | 2016-11-10 | Lunatech, Llc | Device To Deliver Cannabidiol And Associated Compounds To Promote Health |
| AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
| EP3340982B1 (en) | 2015-08-26 | 2021-12-15 | Achillion Pharmaceuticals, Inc. | Compounds for treatment of immune and inflammatory disorders |
| KR102122887B1 (ko) | 2016-05-03 | 2020-06-16 | 뉴마 레스퍼러토리 인코포레이티드 | 유체들의 폐기관계로의 전달을 위한 액적 전달 디바이스 및 사용 방법 |
| EP4624054A3 (en) * | 2016-05-03 | 2025-11-19 | Pneuma Respiratory, Inc. | Methods for generating and delivering droplets to the pulmonary system using a droplet delivery device |
| EP3455219A4 (en) | 2016-05-10 | 2019-12-18 | C4 Therapeutics, Inc. | AMINE-RELATED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN REDUCTION |
| CN109414441A (zh) | 2016-06-27 | 2019-03-01 | 艾其林医药公司 | 治疗医学障碍的喹唑啉和吲哚化合物 |
| US10933208B2 (en) * | 2016-11-14 | 2021-03-02 | Vandana M. Krishna | Asthma inhaler accessory |
| KR102632860B1 (ko) | 2017-03-01 | 2024-02-02 | 아칠리온 파르마세우티칼스 인코포레이티드 | 의학적 장애의 치료를 위한 아릴, 헤테로아릴, 및 헤테로사이클릭 약학적 화합물 |
| CN108531929B (zh) * | 2017-03-03 | 2021-04-13 | 林信涌 | 气体产生器 |
| EP4223335A3 (en) * | 2017-05-19 | 2023-11-08 | Pneuma Respiratory, Inc. | Dry powder delivery device and methods of use |
| RU2761750C2 (ru) * | 2017-05-31 | 2021-12-13 | Филип Моррис Продактс С.А. | Ингаляционное изделие с закрывающим элементом для потока воздуха |
| EP3641762B1 (en) | 2017-06-20 | 2026-02-18 | C4 Therapeutics, Inc. | N/o-linked degrons and degronimers for protein degradation |
| CN110891637B (zh) * | 2017-07-07 | 2022-06-21 | 皇家飞利浦有限公司 | 用于将药剂分散到通气回路中的气溶胶药剂递送适配器和系统 |
| CN118203735A (zh) | 2017-10-04 | 2024-06-18 | 精呼吸股份有限公司 | 电子呼吸致动式直线型液滴输送装置及其使用方法 |
| CA3082192A1 (en) | 2017-11-08 | 2019-05-16 | Pneuma Respiratory, Inc. | Electronic breath actuated in-line droplet delivery device with small volume ampoule and methods of use |
| US10953164B2 (en) * | 2018-03-05 | 2021-03-23 | Argospire Medical Inc. | Portable inhalation therapeutic and inhalation and exhalation measuring devices and related methods |
| CN111902179B (zh) * | 2018-03-21 | 2022-10-28 | 索芙特海尔公司 | 用于吸入装置的喷雾嘴 |
| KR20210018199A (ko) | 2018-03-26 | 2021-02-17 | 씨4 테라퓨틱스, 인코포레이티드 | 이카로스의 분해를 위한 세레블론 결합제 |
| US20230022157A1 (en) | 2018-08-20 | 2023-01-26 | Achillion Pharmaceuticals, Inc. | Pharmaceutical compounds for the treatment of complement factor d medical disorders |
| WO2020081723A1 (en) | 2018-10-16 | 2020-04-23 | Georgia State University Research Foundation, Inc. | Carbon monoxide prodrugs for the treatment of medical disorders |
| JP7223852B2 (ja) * | 2018-12-06 | 2023-02-16 | フィリップ・モーリス・プロダクツ・ソシエテ・アノニム | 内側および外側の管状セクションを有するマウスピース |
| CN111284917B (zh) * | 2018-12-07 | 2024-12-10 | 上海上药信谊药厂有限公司 | 气雾剂给药用的驱动器及含其的气雾剂给药系统 |
| MA55628A (fr) | 2019-04-12 | 2022-02-16 | C4 Therapeutics Inc | Agents de dégradation tricycliques d'ikaros et d'aiolos |
| WO2020232238A1 (en) | 2019-05-16 | 2020-11-19 | Aerovate Therapeutics, Inc. | Inhalable formulations for kinase inhibition |
| CN119837855A (zh) | 2019-12-19 | 2025-04-18 | 乔治亚州大学研究基金会 | 用于治疗细菌感染和增强抗生素的化合物 |
| CN115362162A (zh) | 2020-02-20 | 2022-11-18 | 艾其林医药公司 | 用于治疗补体因子d介导的障碍的杂芳基化合物 |
| IL295709A (en) | 2020-03-05 | 2022-10-01 | C4 Therapeutics Inc | Compounds for targeted degradation of brd9 |
| SE544941C2 (en) * | 2020-06-15 | 2023-02-07 | Vivolab Ab | Pacifier comprising an aerosolization device |
| CA3193488A1 (en) | 2020-09-23 | 2022-03-31 | Jason Allan Wiles | Pharmaceutical compounds for the treatment of complement mediated disorders |
| WO2022219591A2 (en) * | 2021-04-14 | 2022-10-20 | Oron Zachar | Intraoral aerosol delivery device |
| WO2022271848A1 (en) | 2021-06-22 | 2022-12-29 | Pneuma Respiratory, Inc. | Droplet delivery device with push ejection |
| CN113750331B (zh) * | 2021-08-18 | 2022-08-16 | 华中科技大学 | 一种干粉吸入器 |
| CN114028662B (zh) * | 2021-11-18 | 2024-04-16 | 苏州海熙智能医疗科技有限公司 | 自适应气雾剂智能辅助给药装置及工作方法 |
| US20260033533A1 (en) | 2022-07-18 | 2026-02-05 | Pneuma Respiratory, Inc. | Small step size and high resolution aerosol generation system and method |
| AU2024235583A1 (en) | 2023-03-15 | 2025-08-14 | Bayer Aktiengesellschaft | Modified valve for use in a flow path |
| CN120401600B (zh) * | 2025-07-02 | 2025-09-02 | 上海核烨工程技术有限公司 | 一种用于核设施水池清洁的水下吸污装置 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3815597A (en) * | 1972-11-24 | 1974-06-11 | W Goettelman | Pipe inhaler |
| US4592348A (en) * | 1984-12-17 | 1986-06-03 | Waters Iv William C | Aerosol inhaler |
| US4976259A (en) | 1986-12-22 | 1990-12-11 | Mountain Medical Equipment, Inc. | Ultrasonic nebulizer |
| US5178138A (en) * | 1990-09-11 | 1993-01-12 | Walstrom Dennis R | Drug delivery device |
| US5040527A (en) * | 1990-12-18 | 1991-08-20 | Healthscan Products Inc. | Metered dose inhalation unit with slide means |
| JPH0871152A (ja) * | 1994-09-02 | 1996-03-19 | Unisia Jecs Corp | 吸入式投薬器 |
| US5522380A (en) | 1995-01-18 | 1996-06-04 | Dwork; Paul | Metered dose medication adaptor with improved incentive spirometer |
| DE19536902A1 (de) * | 1995-10-04 | 1997-04-10 | Boehringer Ingelheim Int | Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung |
| US5839430A (en) * | 1996-04-26 | 1998-11-24 | Cama; Joseph | Combination inhaler and peak flow rate meter |
| US6962151B1 (en) | 1999-11-05 | 2005-11-08 | Pari GmbH Spezialisten für effektive Inhalation | Inhalation nebulizer |
| US7600511B2 (en) * | 2001-11-01 | 2009-10-13 | Novartis Pharma Ag | Apparatus and methods for delivery of medicament to a respiratory system |
| DE10102846B4 (de) * | 2001-01-23 | 2012-04-12 | Pari Pharma Gmbh | Aerosolgenerator |
| US7766013B2 (en) * | 2001-06-05 | 2010-08-03 | Alexza Pharmaceuticals, Inc. | Aerosol generating method and device |
| GB0128148D0 (en) * | 2001-11-23 | 2002-01-16 | Innovata Biomed Ltd | Assembly |
| FI20020909A0 (fi) * | 2002-05-14 | 2002-05-14 | Perlos Oyj | Inhalaattori, inhalaattorin komponentti ja menetelmä sellaisen valmistamiseksi |
| US20050133025A1 (en) * | 2002-05-14 | 2005-06-23 | Juha Laiho | Inhalator and method of manufacturing same |
| US7267121B2 (en) | 2004-04-20 | 2007-09-11 | Aerogen, Inc. | Aerosol delivery apparatus and method for pressure-assisted breathing systems |
| US7721734B2 (en) | 2004-05-14 | 2010-05-25 | Carefusion 2200, Inc. | Inhalation apparatus |
| JP2008515606A (ja) * | 2004-10-12 | 2008-05-15 | アラダイム コーポレーション | 液体製剤からエアロゾルを生成し、その無菌性を保証するための装置および方法 |
| JP2006212203A (ja) | 2005-02-03 | 2006-08-17 | Canon Inc | 吸入装置、及び液剤吐出カートリッジ |
| DE102005010965B3 (de) | 2005-03-10 | 2006-08-03 | Medspray Xmems Bv | Inhalator mit einem Mischkanal zum Erzeugen eines zu inhalierenden Aerosols |
| DE102005016102B3 (de) * | 2005-04-08 | 2006-10-26 | Altana Pharma Ag | Vorrichtung zur Dosierung und Trockenvernebelung |
| DE102005029498B4 (de) | 2005-06-24 | 2007-08-30 | Pari GmbH Spezialisten für effektive Inhalation | Inhalationstherapievorrichtung |
| WO2007116953A1 (en) | 2006-04-10 | 2007-10-18 | Canon Kabushiki Kaisha | Ingesta administration device |
| JP5207679B2 (ja) | 2006-08-01 | 2013-06-12 | キヤノン株式会社 | 薬剤吐出装置 |
| US20100180890A1 (en) | 2006-09-29 | 2010-07-22 | Canon Kabushiki Kaisha | Inhaler |
| FR2908329B1 (fr) | 2006-11-14 | 2011-01-07 | Telemaq | Dispositif et methode de distribution de fluide par ultrasons |
| US20080202506A1 (en) | 2007-02-27 | 2008-08-28 | Mahoney Derek D | Waterfall nebulizer |
| EP2203155A1 (en) | 2007-09-25 | 2010-07-07 | Novartis Ag | Treatment of pulmonary disorders with aerosolized medicaments such as vancomycin |
| JP2009268665A (ja) | 2008-05-07 | 2009-11-19 | Canon Inc | 吸入装置 |
| DE102008022987A1 (de) | 2008-05-09 | 2009-11-12 | Pari Pharma Gmbh | Vernebler für Beatmungsmaschinen und Beatmungsmaschine mit einem solchen Vernebler |
| WO2010065616A1 (en) * | 2008-12-02 | 2010-06-10 | Thermocure, Inc. | Systems and methods for delivery of a breathing gas with fine ice particles |
| DE102008054431B3 (de) | 2008-12-09 | 2010-06-17 | Pari Pharma Gmbh | Aerosoltherapievorrichtung |
| US20100196483A1 (en) | 2009-02-04 | 2010-08-05 | Activaero Gmbh Research & Development | Method for treatmentof severe and uncontrollable asthma |
| EP2445558B1 (en) * | 2009-06-25 | 2016-06-29 | Boehringer Ingelheim Vetmedica GmbH | Inhaler |
| CN102019028B (zh) * | 2009-09-17 | 2013-09-11 | 纪欣 | 体内干粉输送装置 |
| IL223742A (en) | 2010-06-21 | 2016-06-30 | Mannkind Corp | A dry powder inhaler and preparation for it |
| DK2797652T3 (en) | 2011-12-27 | 2019-03-11 | Vectura Gmbh | FEEDBACK SYSTEM INHALATION DEVICE |
-
2013
- 2013-03-08 PL PL13714561T patent/PL2846859T3/pl unknown
- 2013-03-08 JP JP2014560389A patent/JP6174056B2/ja active Active
- 2013-03-08 PT PT137145611T patent/PT2846859T/pt unknown
- 2013-03-08 ES ES13714561.1T patent/ES2619959T3/es active Active
- 2013-03-08 EP EP16192453.5A patent/EP3146990B1/en active Active
- 2013-03-08 AU AU2013229447A patent/AU2013229447B2/en active Active
- 2013-03-08 HU HUE13714561A patent/HUE033664T2/en unknown
- 2013-03-08 NZ NZ628562A patent/NZ628562A/en unknown
- 2013-03-08 CN CN201711318505.2A patent/CN107929894B/zh active Active
- 2013-03-08 EP EP13714561.1A patent/EP2846859B1/en active Active
- 2013-03-08 CA CA2984393A patent/CA2984393C/en active Active
- 2013-03-08 IN IN8290DEN2014 patent/IN2014DN08290A/en unknown
- 2013-03-08 KR KR1020147024619A patent/KR101903028B1/ko active Active
- 2013-03-08 US US14/382,392 patent/US10857310B2/en active Active
- 2013-03-08 CA CA2866632A patent/CA2866632C/en active Active
- 2013-03-08 WO PCT/EP2013/054705 patent/WO2013132056A1/en not_active Ceased
- 2013-03-08 CN CN201380013156.7A patent/CN104271187B/zh active Active
- 2013-03-08 DK DK13714561.1T patent/DK2846859T3/en active
- 2013-03-08 RU RU2014140751A patent/RU2618917C2/ru active
- 2013-03-08 SG SG11201405061VA patent/SG11201405061VA/en unknown
- 2013-03-08 SI SI201330578A patent/SI2846859T1/sl unknown
-
2017
- 2017-07-04 JP JP2017130917A patent/JP6514277B2/ja active Active
-
2020
- 2020-11-10 US US17/093,710 patent/US20210196904A1/en not_active Abandoned
-
2023
- 2023-10-05 US US18/377,084 patent/US12251506B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US12251506B2 (en) | Mixing channel for an inhalation device and inhalation device | |
| ES2648196T3 (es) | Dispositivo aerosol circunferencial | |
| ES3041314T3 (en) | Nasal spray/spout nozzle and nasal rest article for nasal administration | |
| ES2702981T3 (es) | Nebulizador nasal para irrigación y suministro de fármacos | |
| ES2635056T3 (es) | Dispositivo de inhalación para su uso en terapia de aerosol | |
| US7819342B2 (en) | Atomizer for dispensing liquids for medical purposes | |
| ES2599302T3 (es) | Inhalador | |
| ES2606548T3 (es) | Un inhalador que opera con la respiración con chorros de aire que inciden sobre una pluma | |
| CN112996605A (zh) | 低表面张力组合物经由电子呼吸致动式液滴递送装置向肺系统的递送 | |
| KR102446255B1 (ko) | 에어로졸 발생기 | |
| ES2833107T3 (es) | Un dispositivo de suministro de medicamento nasal | |
| ES2772710T3 (es) | Inhalador de polvo seco | |
| ES3062704T3 (en) | Multiliquid-nozzle | |
| ES2963549T3 (es) | Cánula nasal con nebulizador integrado | |
| HK1207011B (en) | Mixing channel for an inhalation device and inhalation device | |
| HK40053283A (en) | Delivery of low surface tension compositions to the pulmonary system via electronic breath actuated droplet delivery device | |
| EP3641946A1 (en) | Aerosol delivery of pirfenidone |