ES260973A1 - Procedimiento para preparar nuevos compuestos n-heterociclicos - Google Patents

Procedimiento para preparar nuevos compuestos n-heterociclicos

Info

Publication number
ES260973A1
ES260973A1 ES0260973A ES260973A ES260973A1 ES 260973 A1 ES260973 A1 ES 260973A1 ES 0260973 A ES0260973 A ES 0260973A ES 260973 A ES260973 A ES 260973A ES 260973 A1 ES260973 A1 ES 260973A1
Authority
ES
Spain
Prior art keywords
general formula
reacting
represent
amine
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0260973A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH7749159A external-priority patent/CH377824A/de
Application filed by JR Geigy AG filed Critical JR Geigy AG
Publication of ES260973A1 publication Critical patent/ES260973A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
    • C07D223/28—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a single bond between positions 10 and 11
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
    • C07D223/26—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a double bond between positions 10 and 11

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

Procedimiento para preparar nuevos compuestos N-heterocíclicos de la fórmula general *** en la que Y representa hidrógeno o un átomo de halógeno, z representa hidrógeno o un átomo de halógeno, uno de los símbolos R1 y R2 representa el grupo metilo, mientras el otro representa hidrógeno, y R3 y R4 representan radicales inferiores de alquenilo o radicales inferiores de alkilo, que pueden estar finidos entre sí directamente o por medio de un átomo de oxígeno o de un grupo alkilimino, alcanoiloxialkilimino o hidroxialkilimino, debiendo R2 y un radical alkilo R3 poseer juntos dos átomos de carbono por lo menos, procedimiento caracterizado por el hecho de que se hace reaccionar un iminodibencilo, eventualmente substituido, de la fórmula general
ES0260973A 1959-08-28 1960-08-27 Procedimiento para preparar nuevos compuestos n-heterociclicos Expired ES260973A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH7749159A CH377824A (de) 1959-08-28 1959-08-28 Verfahren zur Herstellung von neuen N-heterocyclischen Verbindungen
CH29960 1960-01-13
CH210860 1960-02-25

Publications (1)

Publication Number Publication Date
ES260973A1 true ES260973A1 (es) 1961-01-16

Family

ID=27171972

Family Applications (5)

Application Number Title Priority Date Filing Date
ES0260974A Expired ES260974A1 (es) 1959-08-28 1960-08-27 Procedimiento para preparar nuevos compuestos n-heterociclicos
ES0260973A Expired ES260973A1 (es) 1959-08-28 1960-08-27 Procedimiento para preparar nuevos compuestos n-heterociclicos
ES0260978A Expired ES260978A1 (es) 1959-08-28 1960-08-27 Procedimiento para preparar nuevos compuestos n-heterociclicos
ES0260976A Expired ES260976A1 (es) 1959-08-28 1960-08-27 Procedimiento para preparar nuevos compuestos n-heterociclicos
ES0260975A Expired ES260975A1 (es) 1959-08-28 1960-08-27 Procedimiento para preparar nuevos compuestos n-heterociclicos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES0260974A Expired ES260974A1 (es) 1959-08-28 1960-08-27 Procedimiento para preparar nuevos compuestos n-heterociclicos

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES0260978A Expired ES260978A1 (es) 1959-08-28 1960-08-27 Procedimiento para preparar nuevos compuestos n-heterociclicos
ES0260976A Expired ES260976A1 (es) 1959-08-28 1960-08-27 Procedimiento para preparar nuevos compuestos n-heterociclicos
ES0260975A Expired ES260975A1 (es) 1959-08-28 1960-08-27 Procedimiento para preparar nuevos compuestos n-heterociclicos

Country Status (8)

Country Link
US (3) US3505314A (es)
BE (2) BE594436A (es)
DE (2) DE1182238B (es)
ES (5) ES260974A1 (es)
FR (1) FR772M (es)
GB (2) GB962462A (es)
MY (2) MY6700079A (es)
NL (1) NL255316A (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3692906A (en) * 1970-06-24 1972-09-19 Colgate Palmolive Co Method of treating hypertension with morphanthridines
WO2008131368A2 (en) 2007-04-20 2008-10-30 Acucela Inc. Styrenyl derivative compounds for treating ophthalmic diseases and disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3074931A (en) * 1963-01-22 Dibenzazepines
US2554736A (en) * 1951-05-29 Tertiary aminoalkyl-iminodibenzyls
DE1006421B (de) * 1952-01-25 1957-04-18 Geigy Ag J R Verfahren zur Herstellung von basischen Derivaten des Iminodibenzyls
AT200578B (de) * 1956-11-13 1958-11-10 Geigy Ag J R Verfahren zur Herstellung von neuen N-Aminoalkylderivaten von Azepinen

Also Published As

Publication number Publication date
GB962462A (en) 1964-07-01
NL255316A (es)
DE1182238B (de) 1964-11-26
MY6700085A (en) 1967-12-31
FR772M (fr) 1961-08-11
BE594436A (fr) 1961-02-27
US3591691A (en) 1971-07-06
US3444159A (en) 1969-05-13
BE594437A (fr) 1961-02-27
ES260976A1 (es) 1961-01-16
ES260975A1 (es) 1961-01-16
ES260974A1 (es) 1961-01-16
GB962461A (en) 1964-07-01
MY6700079A (en) 1967-12-31
DE1192211B (de) 1965-05-06
ES260978A1 (es) 1961-01-16
US3505314A (en) 1970-04-07

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