ES2602977T3 - Biomarcadores de citocinas como biomarcadores predictivos de la respuesta clínica para acetato de glatirámero - Google Patents
Biomarcadores de citocinas como biomarcadores predictivos de la respuesta clínica para acetato de glatirámero Download PDFInfo
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- ES2602977T3 ES2602977T3 ES11833199.0T ES11833199T ES2602977T3 ES 2602977 T3 ES2602977 T3 ES 2602977T3 ES 11833199 T ES11833199 T ES 11833199T ES 2602977 T3 ES2602977 T3 ES 2602977T3
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- glatiramer acetate
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- human subject
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- multiple sclerosis
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- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- G—PHYSICS
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- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
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- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/555—Interferons [IFN]
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- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
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| US391968P | 2010-10-11 | ||
| PCT/US2011/055588 WO2012051106A1 (en) | 2010-10-11 | 2011-10-10 | Cytokine biomarkers as predictive biomarkers of clinical response for glatiramer acetate |
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| ES2602977T3 true ES2602977T3 (es) | 2017-02-23 |
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| SI2405749T1 (sl) | 2009-08-20 | 2013-10-30 | Yeda Research And Development Co., Ltd. | Nizkofrekventna terapija z glatiramer acetatom |
| USRE49251E1 (en) | 2010-01-04 | 2022-10-18 | Mapi Pharma Ltd. | Depot systems comprising glatiramer or pharmacologically acceptable salt thereof |
| PT2627669T (pt) | 2010-10-11 | 2016-11-24 | Teva Pharma | Biomarcadores de citocina como biomarcadores preditivos de resposta clínica para acetato de glatirâmero |
| MX2014004309A (es) | 2011-10-10 | 2015-07-06 | Teva Pharma | Polimorfismos de nucleotidos individuales utiles para predecir una respuesta clinica para el acetato de glatiramer. |
| US9617596B2 (en) | 2012-10-10 | 2017-04-11 | Teva Pharmaceutical Industries, Ltd. | Biomarkers predictive for clinical response for glatiramer acetate |
| CN105377308B (zh) | 2013-03-14 | 2019-07-26 | 迈兰公司 | 醋酸格拉替雷响应生物标志物mRNA效力测定 |
| UY35790A (es) | 2013-10-21 | 2015-05-29 | Teva Pharma | Marcadores genéticos que predicen la respuesta al acetato de glatiramer |
| US9995734B2 (en) | 2013-10-24 | 2018-06-12 | Mylan Inc. | Human T cell line assay for evaluating the immunologic identity of glatiramer acetate preparations |
| US9155775B1 (en) | 2015-01-28 | 2015-10-13 | Teva Pharmaceutical Industries, Ltd. | Process for manufacturing glatiramer acetate product |
| US20160213633A1 (en) * | 2015-01-28 | 2016-07-28 | Teva Pharmaceutical Industries, Ltd. | Method of inducing anti-glatiramer acetate antibody response |
| US12097292B2 (en) | 2016-08-28 | 2024-09-24 | Mapi Pharma Ltd. | Process for preparing microparticles containing glatiramer acetate |
| SI3506921T1 (sl) | 2016-08-31 | 2023-10-30 | Mapi Pharma Ltd. | Depojski sistemi, ki vsebujejo glatiramer acetat |
| JP7602322B2 (ja) | 2017-03-26 | 2024-12-18 | マピ ファーマ リミテッド | 進行型の多発性硬化症を治療するためのグラチラマーデポシステム |
| WO2020047026A1 (en) * | 2018-08-30 | 2020-03-05 | Essen Instruments, Inc. D/B/A Essen Bioscience, Inc. | Methods for determining concentration of low and high concentration proteins in a single sample |
| WO2025181335A1 (en) * | 2024-02-29 | 2025-09-04 | Grifols Worldwide Operations Limited | Methods of treating a cognitive impairment |
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| SI2405749T1 (sl) | 2009-08-20 | 2013-10-30 | Yeda Research And Development Co., Ltd. | Nizkofrekventna terapija z glatiramer acetatom |
| US8759302B2 (en) * | 2010-03-16 | 2014-06-24 | Teva Pharmaceutical Industries, Ltd. | Methods of treating a subject afflicted with an autoimmune disease using predictive biomarkers of clinical response to glatiramer acetate therapy in multiple sclerosis |
| PT2627669T (pt) | 2010-10-11 | 2016-11-24 | Teva Pharma | Biomarcadores de citocina como biomarcadores preditivos de resposta clínica para acetato de glatirâmero |
| MX2014004309A (es) | 2011-10-10 | 2015-07-06 | Teva Pharma | Polimorfismos de nucleotidos individuales utiles para predecir una respuesta clinica para el acetato de glatiramer. |
| US9617596B2 (en) | 2012-10-10 | 2017-04-11 | Teva Pharmaceutical Industries, Ltd. | Biomarkers predictive for clinical response for glatiramer acetate |
| US20160193276A1 (en) | 2012-12-21 | 2016-07-07 | Teva Pharmaceutical Industries, Ltd. | Transmucosal delivery of glatiramer acetate |
| KR20150111919A (ko) | 2012-12-21 | 2015-10-06 | 테바 파마슈티컬 인더스트리즈 리미티드 | 글라티라머 아세테이트의 경구 경점막 전달 |
| MX2015008754A (es) | 2013-01-04 | 2016-04-11 | Teva Pharma | Caracterizacion de un medicamento relacionado con acetato de glatiramer. |
| CA2903127A1 (en) | 2013-03-12 | 2014-10-09 | Teva Pharmaceutical Industries Ltd. | Rituximab induction therapy followed by glatiramer acetate therapy |
| UY35790A (es) | 2013-10-21 | 2015-05-29 | Teva Pharma | Marcadores genéticos que predicen la respuesta al acetato de glatiramer |
| US9155775B1 (en) | 2015-01-28 | 2015-10-13 | Teva Pharmaceutical Industries, Ltd. | Process for manufacturing glatiramer acetate product |
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Also Published As
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| KR20140019296A (ko) | 2014-02-14 |
| PL2627669T3 (pl) | 2017-02-28 |
| BR112013008573A2 (pt) | 2016-07-12 |
| EP2627669A1 (en) | 2013-08-21 |
| US20140294899A1 (en) | 2014-10-02 |
| AU2011313842B2 (en) | 2016-12-15 |
| US20150241446A1 (en) | 2015-08-27 |
| WO2012051106A1 (en) | 2012-04-19 |
| EA025780B1 (ru) | 2017-01-30 |
| NZ609938A (en) | 2015-11-27 |
| US9063153B2 (en) | 2015-06-23 |
| US8709433B2 (en) | 2014-04-29 |
| JP2016188214A (ja) | 2016-11-04 |
| CA2814500A1 (en) | 2012-04-19 |
| NZ703122A (en) | 2016-06-24 |
| EA201390543A1 (ru) | 2013-09-30 |
| MX2013003929A (es) | 2013-07-05 |
| US9625473B2 (en) | 2017-04-18 |
| JP2013541010A (ja) | 2013-11-07 |
| EP2627669A4 (en) | 2014-04-09 |
| AU2011313842A1 (en) | 2013-05-30 |
| EP2627669B1 (en) | 2016-08-17 |
| MX347871B (es) | 2017-05-16 |
| IL225118A (en) | 2017-10-31 |
| PT2627669T (pt) | 2016-11-24 |
| US20120121619A1 (en) | 2012-05-17 |
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