ES2588507T3 - CCR4 como diana terapéutica para cáncer - Google Patents
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- ES2588507T3 ES2588507T3 ES12182790.1T ES12182790T ES2588507T3 ES 2588507 T3 ES2588507 T3 ES 2588507T3 ES 12182790 T ES12182790 T ES 12182790T ES 2588507 T3 ES2588507 T3 ES 2588507T3
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- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
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- G01N2800/00—Detection or diagnosis of diseases
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Landscapes
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- Genetics & Genomics (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| ES08806315.1T Active ES2443541T3 (es) | 2007-09-18 | 2008-09-18 | CCR4 como marcador de cáncer |
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| ES12183760.3T Active ES2612690T3 (es) | 2007-09-18 | 2008-09-18 | Marcador de cáncer y diana terapéutica |
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| JPH0623815Y2 (ja) | 1988-10-06 | 1994-06-22 | 株式会社大金製作所 | エア回転継手のシール装置 |
| GB0718167D0 (en) | 2007-09-18 | 2007-10-31 | Cancer Rec Tech Ltd | Cancer marker and therapeutic target |
| US11029313B2 (en) | 2008-09-26 | 2021-06-08 | The General Hospital Corporation | Method of treating cervical neoplasia in patients infected with human papilloma virus |
| US9229004B2 (en) | 2008-09-26 | 2016-01-05 | The General Hospital Corporation | Methods for detecting and treating cancer |
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| US10266599B2 (en) | 2010-12-07 | 2019-04-23 | Cancer Research Technology Limited | Antibodies which bind to the human CC chemokine receptor 4 and uses thereof |
| GB201020738D0 (en) | 2010-12-07 | 2011-01-19 | Affitech Res As | Antibodies |
| JP6259764B2 (ja) * | 2011-10-24 | 2018-01-10 | シグナルケム・ライフサイエンシーズ・コーポレイションＳｉｇｎａｌｃｈｅｍ Ｌｉｆｅｓｃｉｅｎｃｅｓ Ｃｏｒｐｏｒａｔｉｏｎ | 炭酸脱水酵素関連マーカーおよびその使用 |
| JP6141864B2 (ja) | 2011-12-01 | 2017-06-07 | ケモセントリックス，インコーポレイティド | Ｃｃｒ（４）アンタゴニストとしての置換アニリン |
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| US10155818B2 (en) | 2014-05-28 | 2018-12-18 | Agenus Inc. | Anti-GITR antibodies and methods of use thereof |
| WO2016050904A1 (en) * | 2014-10-01 | 2016-04-07 | Sphingotec Gmbh | Hgh determination for use to guide prevention of a major adverse cardiac event or a cardiovascular disease in a subject |
| MX2017013390A (es) * | 2015-04-17 | 2018-06-13 | Morphotek Inc | Método para el tratamiento de cáncer pulmonar. |
| WO2017017283A1 (en) | 2015-07-30 | 2017-02-02 | Qiagen Gmbh | Method of preparing a frozen biological sample |
| CA3007233A1 (en) | 2015-12-02 | 2017-06-08 | Agenus Inc. | Antibodies and methods of use thereof |
| EP3626269A4 (en) * | 2017-05-19 | 2021-03-03 | Shingo Maeda | Method for inhibiting regulatory t cell infiltration using ccr4 inhibition and method for treating canine neoplastic disease |
| CA3109498A1 (en) | 2018-08-29 | 2020-03-05 | Chemocentryx, Inc. | Combination therapy using c-c chemokine receptor 4 (ccr4) antagonists and one or more immune checkpoint inhibitors |
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| US5342947A (en) * | 1992-10-09 | 1994-08-30 | Glaxo Inc. | Preparation of water soluble camptothecin derivatives |
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| US6245332B1 (en) | 1999-01-15 | 2001-06-12 | The Board Of Trustees Of The Leland Stanford Junior University | Modulation of systemic memory T cell trafficking |
| US6488930B1 (en) | 1999-01-15 | 2002-12-03 | Millennium Pharmaceuticals, Inc. | Anti-CCR4 antibodies and methods of use therefor |
| KR100890873B1 (ko) | 2000-03-03 | 2009-03-31 | 교와 핫꼬 기린 가부시키가이샤 | 유전자 재조합 항체 및 이의 항체 단편 |
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| CA2425259A1 (en) | 2000-10-11 | 2002-04-18 | Tularik, Inc. | Modulation of ccr4 function |
| HUP0301433A3 (en) | 2000-10-18 | 2010-01-28 | Schering Ag | Use of antiprogestins for producung pharmaceutical compositions for induction of apoptosis in a cell |
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| US20050101530A1 (en) | 2001-08-10 | 2005-05-12 | Topigen Pharmaceutique, Inc. | Cellular virus receptors and methods of use |
| ATE490277T1 (de) | 2001-08-31 | 2010-12-15 | Kyowa Hakko Kirin Co Ltd | Mit humanem cdr gepfropfte antikörper und antikörperfragmente davon |
| US20060004010A1 (en) | 2002-07-10 | 2006-01-05 | Hiromu Habashita | Ccr4 antagonist and medical use thereof |
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| EP2058408A3 (en) * | 2003-02-14 | 2009-09-09 | Sagres Discovery, Inc. | Therapeutic GPCR targets in cancer |
| US7807389B2 (en) | 2003-03-14 | 2010-10-05 | University Of Rochester | Methods and compositions related to joint inflammation diseases |
| SE0301650D0 (sv) | 2003-06-04 | 2003-06-04 | Astrazeneca Ab | Novel compounds |
| SE0301653D0 (sv) | 2003-06-05 | 2003-06-05 | Astrazeneca Ab | Novel compounds |
| WO2005023771A1 (ja) | 2003-09-05 | 2005-03-17 | Ono Pharmaceutical Co., Ltd. | ケモカインレセプターアンタゴニストおよびその医薬用途 |
| EP1688436A4 (en) * | 2003-10-08 | 2009-12-02 | Kyowa Hakko Kirin Co Ltd | ANTIBODY COMPOSITION THAT IS ABLE TO SPECIFY CCR4 SPECIFICALLY |
| CA2548454C (en) | 2003-12-04 | 2013-12-31 | Kyowa Hakko Kogyo Co., Ltd. | Medicament comprising recombinant antibody against chemokine receptor ccr4 |
| WO2005082865A1 (ja) | 2004-02-27 | 2005-09-09 | Astellas Pharma Inc. | 縮合二環性ピリミジン誘導体 |
| JP2007217282A (ja) | 2004-03-04 | 2007-08-30 | Astellas Pharma Inc | 置換ピリミジン誘導体 |
| WO2005106471A2 (en) | 2004-04-30 | 2005-11-10 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with c-c chemokine receptor 4 (ccr4) |
| JP2007269629A (ja) | 2004-06-21 | 2007-10-18 | Astellas Pharma Inc | キナゾリン誘導体 |
| RU2296328C1 (ru) * | 2005-09-21 | 2007-03-27 | Общество с ограниченной ответственностью "ГЕН" | Способ определения предрасположенности к онкологическим заболеваниям и диагностический набор для его осуществления |
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| CN103275984A (zh) | 2006-02-14 | 2013-09-04 | 诺松制药股份公司 | 结合mcp-1的核酸 |
| GB0718167D0 (en) | 2007-09-18 | 2007-10-31 | Cancer Rec Tech Ltd | Cancer marker and therapeutic target |
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| RU2010123921A (ru) | 2011-12-20 |
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| DK2533047T3 (en) | 2016-08-22 |
| US20100278844A1 (en) | 2010-11-04 |
| RU2529797C2 (ru) | 2014-09-27 |
| EP2176664B1 (en) | 2013-11-06 |
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| AU2008300413A1 (en) | 2009-03-26 |
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| CA2699702C (en) | 2018-03-06 |
| PL2535716T3 (pl) | 2017-06-30 |
| ES2612690T3 (es) | 2017-05-18 |
| EP2535716A2 (en) | 2012-12-19 |
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