ES2572502T3 - Dispositivos de recogida de sangre que contienen un agente de estabilización de la sangre - Google Patents
Dispositivos de recogida de sangre que contienen un agente de estabilización de la sangreInfo
- Publication number
- ES2572502T3 ES2572502T3 ES11844851T ES11844851T ES2572502T3 ES 2572502 T3 ES2572502 T3 ES 2572502T3 ES 11844851 T ES11844851 T ES 11844851T ES 11844851 T ES11844851 T ES 11844851T ES 2572502 T3 ES2572502 T3 ES 2572502T3
- Authority
- ES
- Spain
- Prior art keywords
- blood
- variegina
- seq
- collection devices
- devices containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/153—Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
- A61B5/154—Devices using pre-evacuated means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150015—Source of blood
- A61B5/15003—Source of blood for venous or arterial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150251—Collection chamber divided into at least two compartments, e.g. for division of samples
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150305—Packages specially adapted for piercing devices or blood sampling devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150351—Caps, stoppers or lids for sealing or closing a blood collection vessel or container, e.g. a test-tube or syringe barrel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150755—Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5082—Test tubes per se
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Manufacturing & Machinery (AREA)
- Diabetes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- External Artificial Organs (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Un dispositivo para recoger y estabilizar sangre o un componente de la misma, donde el dispositivo tiene un primer extremo y un segundo extremo y al menos una pared interior que define una parte de depósito para recibir sangre, en el que el depósito contiene un agente de estabilización de la sangre que comprende a) variegina que tiene la secuencia de aminoácidos designada SEQ ID NO: 1, o un análogo de la misma tal como el análogo de variegina que es un fragmento de la SEQ ID NO: 1 y que se selecciona de las SEQ ID NO: 2-5, o el análogo de variegina que se designa SEQ ID NO: 6; o b) un disacárido polisulfatado, preferentemente octasulfato de sacarosa, o una combinación de los mismos, cada uno en una cantidad eficaz para estabilizar la sangre o un componente de la misma, en el que la variegina designada SEQ ID NO: 1 o el análogo de la misma pueden estar presentes en el dispositivo en una concentración de aproximadamente 1 μM a aproximadamente 1 mM, y en el que el disacárido polisulfatado puede estar presente en el dispositivo en una concentración de aproximadamente 50 μM a aproximadamente 50 mM.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41906310P | 2010-12-02 | 2010-12-02 | |
PCT/US2011/063086 WO2012075407A2 (en) | 2010-12-02 | 2011-12-02 | Blood collection devices containing blood stabilization agent |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2572502T3 true ES2572502T3 (es) | 2016-05-31 |
Family
ID=46172595
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES11844851T Active ES2572502T3 (es) | 2010-12-02 | 2011-12-02 | Dispositivos de recogida de sangre que contienen un agente de estabilización de la sangre |
Country Status (10)
Country | Link |
---|---|
US (1) | US10299714B2 (es) |
EP (1) | EP2645932B1 (es) |
JP (1) | JP5937612B2 (es) |
CN (1) | CN103384496B (es) |
AU (1) | AU2011336345B2 (es) |
BR (1) | BR112013013414B1 (es) |
CA (1) | CA2818522C (es) |
ES (1) | ES2572502T3 (es) |
MX (1) | MX346717B (es) |
WO (1) | WO2012075407A2 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2598660B1 (en) | 2010-07-26 | 2017-03-15 | Biomatrica, INC. | Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures |
CA2897336C (en) | 2013-01-20 | 2023-10-17 | Dyax Corp. | Evaluation and treatment of pkal-mediated disorders |
CN105188535A (zh) * | 2013-02-01 | 2015-12-23 | 贝克顿·迪金森公司 | 含有接触途径抑制添加剂的血液采集装置 |
PL3060582T3 (pl) | 2013-10-21 | 2021-05-04 | Dyax Corp. | Testy do oznaczania biomarkerów układu kalikreiny osoczowej |
EP3154338B1 (en) * | 2014-06-10 | 2020-01-29 | Biomatrica, INC. | Stabilization of thrombocytes at ambient temperatures |
CN104068867A (zh) * | 2014-06-27 | 2014-10-01 | 安徽信灵检验医学科技有限公司 | 一种真空采血系统及其使用方法 |
EP3099235B8 (en) | 2014-07-02 | 2017-11-29 | Site Saver, Inc. | Venous access device |
CN104634628B (zh) * | 2014-12-16 | 2017-03-29 | 广东腾飞基因科技有限公司 | 一种血液稳定剂及其应用 |
KR102555147B1 (ko) * | 2015-01-22 | 2023-07-13 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 혈소판 풍부 혈장 및 골수 흡인물 세포 분리 및 제거 방법과 장치 |
JP6903648B2 (ja) * | 2015-10-19 | 2021-07-14 | ダイアックス コーポレーション | 切断高分子量キニノーゲンを検出するイムノアッセイ |
EA038186B1 (ru) * | 2015-11-03 | 2021-07-21 | Хелс Корпорейшн Оф Галилея Медикал Сентр | Устройство и способ для обработки искусственного костного имплантата кровью |
CN108700498B (zh) | 2015-12-08 | 2021-07-13 | 生物马特里卡公司 | 降低红细胞沉降速率 |
CN108342381A (zh) * | 2017-01-24 | 2018-07-31 | 梁建国 | 一种用于稳定保存外周血中循环游离dna的溶剂 |
CN106913348B (zh) * | 2017-03-31 | 2023-06-23 | 汪学耀 | 一种预稀释真空采血管及测量血小板数目的方法 |
CN107201307B (zh) * | 2017-05-27 | 2019-09-13 | 广州基赛生物科技有限公司 | 一种采血管及其应用 |
CN107727587B (zh) * | 2017-09-22 | 2020-06-19 | 宁波瑞源生物科技有限公司 | 一种抗凝血酶ⅲ测定试剂盒及其检测方法 |
CN107569244A (zh) * | 2017-10-16 | 2018-01-12 | 李玉斌 | 一种血管外科用采血管 |
EP3710806A1 (en) * | 2017-11-15 | 2020-09-23 | Radiometer Medical ApS | Heparin-based blood sampler without platelet activation |
DE102018218739B3 (de) * | 2018-11-01 | 2020-03-19 | Sarstedt Ag & Co. Kg | Blutentnahmeröhre und Verfahren zur Präparation |
US20210113127A1 (en) * | 2019-10-16 | 2021-04-22 | Becton, Dickinson And Company | Multi-chamber blood collection device and related systems and methods |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB711779A (en) * | 1950-07-07 | 1954-07-14 | Nat Res Dev | Improvements in or relating to electronic information storage systems and discharge tubes therefor |
JPS6053845A (ja) * | 1983-09-05 | 1985-03-27 | Terumo Corp | 血液分離管 |
NZ236033A (en) * | 1989-11-13 | 1994-11-25 | Davol Inc | Blood pump: filtering with tangential flow separation |
WO1993003748A1 (en) | 1991-08-13 | 1993-03-04 | Temple University - Of The Commonwealth System Of Higher Education | Modulation of blood pressure and inhibition of platelet activation with kininogen fragment |
JPH06192291A (ja) * | 1992-09-07 | 1994-07-12 | Nippon Steel Corp | 新規ペプチドとそれを用いた血小板凝集抑制剤及び血液凝固抑制剤 |
JP2723473B2 (ja) * | 1994-09-22 | 1998-03-09 | ブーク メデイテツク エイ/エス | 硫酸化糖類の用途 |
AU703256B2 (en) | 1995-06-09 | 1999-03-25 | Regents Of The University Of Michigan, The | Bradykinin analogs as selective thrombin inhibitors |
US6982249B1 (en) | 1997-04-23 | 2006-01-03 | The Regents Of The University Of Michigan | Bradykinin analogs as selective inhibitors of cell activation |
IL132546A0 (en) | 1997-04-23 | 2001-03-19 | Univ Michigan | Bradykinin analogs as selective inhibitors of cell activation |
US6544750B1 (en) | 1999-08-17 | 2003-04-08 | Thromgen, Inc. | Peptide analogs as selective inhibitors of thrombin activation of protease activated receptor 1 |
UA75093C2 (en) | 2000-10-06 | 2006-03-15 | Dimensional Pharm Inc | Aminopyridinyl-,aminoguanidinyl-, and alkoxyguanidinesubstituted phenylsubstituted phenylacetamides as protease inhibitors |
AUPR612801A0 (en) * | 2001-07-04 | 2001-07-26 | Australian National University, The | Linked cyclitols and their polysulfated derivatives |
CN100389880C (zh) * | 2002-05-07 | 2008-05-28 | 贝克顿·迪金森公司 | 采集组件 |
BR0309976A (pt) | 2002-05-13 | 2005-03-01 | Becton Dickinson Co | Sistema de coleta de amostra inibidor de protease |
EP1413874A1 (en) | 2002-10-16 | 2004-04-28 | Streck Laboratories, Inc. | Method and device for collecting and preserving cells for analysis |
US7074765B2 (en) | 2003-05-01 | 2006-07-11 | The Regents Of The University Of Michigan | Synthetic peptide analogs of Arg-Pro-Pro-Gly-Phe as selective inhibitors of thrombin and thrombin activation of protease activated receptors 1 and 4 |
US20070219131A1 (en) * | 2004-04-15 | 2007-09-20 | Ben-Sasson Shmuel A | Compositions capable of facilitating penetration across a biological barrier |
US20090123907A1 (en) * | 2004-07-22 | 2009-05-14 | Shanbrom Technologies, Llc | Lysine citrate for plasma protein and donor protection |
JP2006288680A (ja) * | 2005-04-11 | 2006-10-26 | Enomoto Co Ltd | 採血キット |
US7879792B2 (en) | 2005-06-02 | 2011-02-01 | The Regents Of The University Of Michigan | Synthetic peptide inhibitors of thrombin and thrombin activation of protease activated receptors 1 and 4 |
JP2008185564A (ja) * | 2007-01-31 | 2008-08-14 | Fujimori Kogyo Co Ltd | 血液凝固能の検査方法および血液凝固能の検査装置 |
GB0711779D0 (en) * | 2007-06-18 | 2007-07-25 | Univ Singapore | Thrombin inhibitor |
WO2009017689A2 (en) * | 2007-08-02 | 2009-02-05 | Government Of The U. S. A., As Represented By The Secretary, Dept. Of Health And Human Services | Methods for detection and prevention of tick infestation and pathogen transmission |
KR101923152B1 (ko) * | 2007-12-04 | 2018-11-28 | 프로테오바이오엑티브스 피티와이 엘티디 | 전구 세포의 보호 및 그의 분화 조절 |
GB0907698D0 (en) * | 2009-05-05 | 2009-06-10 | Univ Singapore | Method of modifying serine protease inhibitors |
-
2011
- 2011-12-02 MX MX2013006073A patent/MX346717B/es active IP Right Grant
- 2011-12-02 CN CN201180058163.XA patent/CN103384496B/zh active Active
- 2011-12-02 WO PCT/US2011/063086 patent/WO2012075407A2/en active Application Filing
- 2011-12-02 US US13/310,084 patent/US10299714B2/en active Active
- 2011-12-02 ES ES11844851T patent/ES2572502T3/es active Active
- 2011-12-02 AU AU2011336345A patent/AU2011336345B2/en active Active
- 2011-12-02 CA CA2818522A patent/CA2818522C/en active Active
- 2011-12-02 BR BR112013013414-3A patent/BR112013013414B1/pt active IP Right Grant
- 2011-12-02 EP EP11844851.3A patent/EP2645932B1/en active Active
- 2011-12-02 JP JP2013542211A patent/JP5937612B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
WO2012075407A2 (en) | 2012-06-07 |
CA2818522A1 (en) | 2012-06-07 |
CN103384496B (zh) | 2016-10-12 |
EP2645932A4 (en) | 2014-06-04 |
MX346717B (es) | 2017-03-29 |
EP2645932A2 (en) | 2013-10-09 |
JP5937612B2 (ja) | 2016-06-22 |
CN103384496A (zh) | 2013-11-06 |
JP2014506319A (ja) | 2014-03-13 |
WO2012075407A3 (en) | 2012-10-04 |
BR112013013414B1 (pt) | 2023-01-10 |
AU2011336345B2 (en) | 2016-07-07 |
US10299714B2 (en) | 2019-05-28 |
AU2011336345A1 (en) | 2013-06-20 |
EP2645932B1 (en) | 2016-03-02 |
US20120149004A1 (en) | 2012-06-14 |
CA2818522C (en) | 2016-05-17 |
MX2013006073A (es) | 2013-07-15 |
BR112013013414A2 (pt) | 2016-09-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2572502T3 (es) | Dispositivos de recogida de sangre que contienen un agente de estabilización de la sangre | |
BR112016016290A2 (pt) | Composições farmacêuticas de insulina de ação rápida, conjunto de infusão, sistema de conjunto de infusão e usos de análogos monoméricos ou diméricos de insulina | |
NI201200013A (es) | Composición de insulina de acción prolongada | |
CL2013002517A1 (es) | Compuestos derivados de fosforoamidato de 5-fluoro-2'-desoxiuridina; procedimiento de preparacion; composicion farmaceutica que los comprende; su uso en el tratamiento o profilaxis del cancer. | |
BR112015018904A2 (pt) | limpador de desinfecção de orifício de acesso e conector sem agulha e cobertura de proteção antimicrobiana | |
PE20130649A1 (es) | Moleculas polinucleotidicas para regulacion genetica en plantas | |
ECSP11011478A (es) | Marcadores de eventos ingeribles altamente confiables y métodos para usarlos | |
WO2016090359A3 (en) | Glass composites for tissue augmentation, biomedical and cosmetic applications | |
CL2015002529A1 (es) | Compuestos de tetrahidropirrolotiazina | |
UY32327A (es) | Antagonistas de receptores de ácido lisofosfatídico | |
BR112018069251A2 (pt) | métodos de intervenção precoce para prevenir ou melhorar a toxicidade | |
BR112015000161A2 (pt) | composições de vetor de vírus adeno-associado modificado | |
AR090465A1 (es) | Formas solidas de un profarmaco de nucleotidos de tiofosforamidato | |
BR112015004704A2 (pt) | sistema de preensão, dispositivo de preensão configurado para prender um artigo médico que tem um corpo alongado, retentor, e dispositivo de preensão configurado para prender um artigo médico que tem um corpo alongado a um paciente | |
BR112015012161A8 (pt) | agente de crioproteção e seu uso, composições de crioproteção e método para criopreservar amostra". | |
DOP2012000314A (es) | Compuestos, composiciones de tiocetato y metodos de uso | |
BR112015001898A2 (pt) | sistema para identificar artefatos de movimentação; e método para identificar artefatos de movimentação | |
BRPI0904882B8 (pt) | dispositivo de acesso cirúrgico | |
EA201200519A1 (ru) | Стабилизированные жидкие и лиофилизированные композиции adamts13 | |
CU20100032A7 (es) | Depsipéptidos cíclicos | |
EA201591152A1 (ru) | Аморфный карбонат кальция для ускоренного роста костной ткани | |
AR078736A1 (es) | Una solucion de droga de taxanos que comprende un regulador de ph y su metodo de preparacion | |
BR112015030355A8 (pt) | uso de uma proteína ou um polipeptídeo de adenilil ciclase tipo 6 (ac6) incompetente com a adenosina monofosfato cíclico (incompetente com camp) ou um gene ou ácido nucléico que codifica ac6mut, e, formulação | |
MX2020004811A (es) | Métodos y composiciones de reconstrucción no mieloablativa de médula ósea. | |
AR101814A1 (es) | Partícula de tipo virus flavivirus |