AR078736A1 - Una solucion de droga de taxanos que comprende un regulador de ph y su metodo de preparacion - Google Patents

Una solucion de droga de taxanos que comprende un regulador de ph y su metodo de preparacion

Info

Publication number
AR078736A1
AR078736A1 ARP100103880A ARP100103880A AR078736A1 AR 078736 A1 AR078736 A1 AR 078736A1 AR P100103880 A ARP100103880 A AR P100103880A AR P100103880 A ARP100103880 A AR P100103880A AR 078736 A1 AR078736 A1 AR 078736A1
Authority
AR
Argentina
Prior art keywords
drug solution
emulsion
regulator
preparation
taxane drug
Prior art date
Application number
ARP100103880A
Other languages
English (en)
Inventor
Jialiang Zhang
Jianming Chen
Baoan Gao
Li Deng
Qiuxia Yang
Jing Sun
Peng Gu
Yingying Zhang
Wei Liu
Original Assignee
Tianjin Tasly Group Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43899845&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR078736(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tianjin Tasly Group Co Ltd filed Critical Tianjin Tasly Group Co Ltd
Publication of AR078736A1 publication Critical patent/AR078736A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

Una solucion de droga de taxano (como por ejemplo, paclitaxel o docetaxel) que comprende un regulador de pH (como por ejemplo: ácido cítrico, láctico, hálico, CIH, acético, fosforico y tartárico y un solvente), método de preparacion y su uso en combinacion con una emulsion. Cuando se utiliza en clínica, la solucion de droga es dispersada en la emulsion y agitada bien, para goteo intravenoso. lnesperadamente, la adicion del regulador de pH prolonga el tiempo de estabiIidad de las drogas dispersadas en la emulsion. Al mismo tiempo, se ha superado el problema del aceite flotante en la superficie de la dispersion mejorando de este modo su seguridad y efectividad en clínica. Más aun, la presente, describe además un método para preparar la solucion de droga de taxanos, una composicion que comprende la solucion de droga de taxanos y una emulsion, y un kit que comprende la solucion de droga de taxanos y una emulsion.
ARP100103880A 2009-10-23 2010-10-22 Una solucion de droga de taxanos que comprende un regulador de ph y su metodo de preparacion AR078736A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2009100709318A CN102038635A (zh) 2009-10-23 2009-10-23 一种含有pH值调节剂的紫杉烷类药物溶液及其制备方法

Publications (1)

Publication Number Publication Date
AR078736A1 true AR078736A1 (es) 2011-11-30

Family

ID=43899845

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100103880A AR078736A1 (es) 2009-10-23 2010-10-22 Una solucion de droga de taxanos que comprende un regulador de ph y su metodo de preparacion

Country Status (11)

Country Link
US (1) US9241922B2 (es)
EP (1) EP2491919B2 (es)
JP (1) JP5847722B2 (es)
KR (1) KR101722398B1 (es)
CN (2) CN102038635A (es)
AR (1) AR078736A1 (es)
AU (1) AU2010310258B2 (es)
CA (1) CA2765748C (es)
HK (1) HK1164708A1 (es)
PL (1) PL2491919T5 (es)
WO (1) WO2011047637A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2205215A2 (en) * 2007-10-01 2010-07-14 Intas Pharmaceuticals Limited Docetaxel injectable composition, being absolutely free of ethanol
EA027666B1 (ru) 2010-05-03 2017-08-31 ТЕИКОКУ ФАРМА ЮСЭй, ИНК. Неводные лекарственные средства в форме проэмульсии на основе таксанов и способы их приготовления и использования
CN101926757B (zh) * 2010-09-01 2013-01-02 北京大学 一种难溶性药物的液体组合物及其制备方法
US8842114B1 (en) 2011-04-29 2014-09-23 Nvidia Corporation System, method, and computer program product for adjusting a depth of displayed objects within a region of a display
JP2013194009A (ja) * 2012-03-21 2013-09-30 Nipro Corp ドセタキセル製剤
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
JP6076744B2 (ja) * 2013-01-04 2017-02-08 ナガセ医薬品株式会社 ドセタキセル含有医薬組成物
JP6292267B2 (ja) * 2016-09-13 2018-03-14 ニプロ株式会社 ドセタキセル製剤
JP2018115178A (ja) * 2018-03-15 2018-07-26 ニプロ株式会社 ドセタキセル製剤
CN111153535B (zh) * 2020-01-19 2022-03-25 武汉市新华印刷有限责任公司 一种显影机冲版废水处理系统

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FR2678833B1 (fr) 1991-07-08 1995-04-07 Rhone Poulenc Rorer Sa Nouvelles compositions pharmaceutiques a base de derives de la classe des taxanes.
US5877205A (en) 1996-06-28 1999-03-02 Board Of Regents, The University Of Texas System Parenteral paclitaxel in a stable non-toxic formulation
US7030155B2 (en) * 1998-06-05 2006-04-18 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
US6136846A (en) * 1999-10-25 2000-10-24 Supergen, Inc. Formulation for paclitaxel
KR20040066921A (ko) 2001-12-20 2004-07-27 브리스톨-마이어스스퀴브컴파니 생체이용률이 향상된 경구 활성 탁산 유도체의 제약조성물
EP1558241A2 (en) 2002-11-08 2005-08-03 Bristol-Myers Squibb Company Pharmaceutical compositions and methods of using taxane derivatives
CN1535679A (zh) 2003-04-04 2004-10-13 齐鲁制药厂 含有紫杉醇类物质的药物组合物及其制备方法
TW200604209A (en) * 2004-03-31 2006-02-01 Showa Denko Kk Moisture retention polymer compound
WO2006033476A1 (en) * 2004-09-24 2006-03-30 Showa Denko K.K. Hydroxycitric acid derivatives and skin external preparations containing the same
US8557861B2 (en) 2004-09-28 2013-10-15 Mast Therapeutics, Inc. Low oil emulsion compositions for delivering taxoids and other insoluble drugs
EP1862183B1 (en) 2005-03-14 2010-11-03 Otsuka Pharmaceutical Factory, Inc. Kit comprising drug and fat emulsion
SG162798A1 (en) * 2005-06-17 2010-07-29 Hospira Australia Pty Ltd Liquid pharmaceutical formulations of docetaxel
JP2007032374A (ja) 2005-07-25 2007-02-08 Usui Kokusai Sangyo Kaisha Ltd フューエルデリバリパイプ
CN101023940A (zh) * 2006-02-20 2007-08-29 郝守祝 一种紫杉烷类化合物的药用组合物、制备方法及用途
US7670997B2 (en) * 2006-06-08 2010-03-02 Bausch & Lomb Incorporated Ophthalmic compositions comprising a branched, glycerol monoalkyl compound and a fatty acid monoester
CN101244053B (zh) * 2007-02-16 2010-12-08 石药集团中奇制药技术（石家庄）有限公司 以多西他赛为主组分的新的分散体系
WO2009002425A2 (en) * 2007-06-22 2008-12-31 Scidose Llc Solubilized formulation of docetaxel without tween 80
EP2205215A2 (en) 2007-10-01 2010-07-14 Intas Pharmaceuticals Limited Docetaxel injectable composition, being absolutely free of ethanol
CN101288642B (zh) * 2007-11-07 2011-04-27 天津天士力集团有限公司 一种紫杉烷类药物静脉给药制剂及其制备方法
US8586062B2 (en) 2007-12-24 2013-11-19 Sun Pharma Advanced Research Company Ltd. Nanodispersion

Also Published As

Publication number Publication date
CN102448441B (zh) 2014-09-17
JP5847722B2 (ja) 2016-01-27
US20120157517A1 (en) 2012-06-21
KR20120087902A (ko) 2012-08-07
EP2491919A4 (en) 2013-09-18
EP2491919B2 (en) 2019-06-26
HK1164708A1 (en) 2012-09-28
CN102038635A (zh) 2011-05-04
PL2491919T5 (pl) 2019-12-31
CN102448441A (zh) 2012-05-09
AU2010310258A1 (en) 2012-01-19
PL2491919T3 (pl) 2017-08-31
CA2765748A1 (en) 2011-04-28
EP2491919B1 (en) 2016-05-11
CA2765748C (en) 2016-10-25
KR101722398B1 (ko) 2017-05-17
AU2010310258B2 (en) 2013-09-19
EP2491919A1 (en) 2012-08-29
US9241922B2 (en) 2016-01-26
WO2011047637A1 (zh) 2011-04-28
JP2013508312A (ja) 2013-03-07

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