ES2572127T3 - Método para detectar el cáncer de páncreas - Google Patents

Método para detectar el cáncer de páncreas

Info

Publication number
ES2572127T3
ES2572127T3 ES11734594T ES11734594T ES2572127T3 ES 2572127 T3 ES2572127 T3 ES 2572127T3 ES 11734594 T ES11734594 T ES 11734594T ES 11734594 T ES11734594 T ES 11734594T ES 2572127 T3 ES2572127 T3 ES 2572127T3
Authority
ES
Spain
Prior art keywords
lectin
pancreatic cancer
pathological
fucose
detect
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES11734594T
Other languages
English (en)
Inventor
Yuka Kobayashi
Ken Kusama
Masugu Kamei
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
J Oil Mills Inc
Original Assignee
J Oil Mills Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by J Oil Mills Inc filed Critical J Oil Mills Inc
Application granted granted Critical
Publication of ES2572127T3 publication Critical patent/ES2572127T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi
    • G01N2333/375—Assays involving biological materials from specific organisms or of a specific nature from fungi from Basidiomycetes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Un método para detectar el cáncer de páncreas, que comprende las etapas de: 1) poner en contacto una lectina específica de fucosa α1→ 6 con una muestra que se ha obtenido de un cuerpo vivo con el fin de dejarse actuar sobre la haptoglobina patológica presente en la muestra y obtener un complejo lectina-haptoglobina patológica, donde dicha lectina: (1) es extraída de basidiomicetos, (2) tiene un peso molecular de 4.000 a 40.000 determinado por el método de electroforesis en gel de poliacrilamida SDS, (3) tiene afinidad por las cadenas de azúcar de fucosa α1→ 6 con una constante de unión de 1,0 x 104 M-1 o mayor a 25°C, y (4) tiene una constante de unión de 1,0 x 103 M-1 o menor para una cadena de azúcar de alto contenido en manosa y/o un glicolípido que no contiene una cadena de azúcar de fucosa α1→ 6 y 2) determinar el complejo lectina-haptoglobina patológica para detectar la existencia del cáncer de páncreas.
ES11734594T 2010-01-21 2011-01-17 Método para detectar el cáncer de páncreas Active ES2572127T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2010011447 2010-01-21
PCT/JP2011/050621 WO2011089988A1 (ja) 2010-01-21 2011-01-17 膵臓癌の検出方法

Publications (1)

Publication Number Publication Date
ES2572127T3 true ES2572127T3 (es) 2016-05-30

Family

ID=44306790

Family Applications (1)

Application Number Title Priority Date Filing Date
ES11734594T Active ES2572127T3 (es) 2010-01-21 2011-01-17 Método para detectar el cáncer de páncreas

Country Status (8)

Country Link
US (1) US8481275B2 (es)
EP (1) EP2498094B1 (es)
JP (1) JP4900983B2 (es)
KR (1) KR101298579B1 (es)
CN (1) CN103348247B (es)
ES (1) ES2572127T3 (es)
RU (1) RU2533219C2 (es)
WO (1) WO2011089988A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5263979B2 (ja) * 2010-01-21 2013-08-14 株式会社Ｊ−オイルミルズ 大腸癌の判別方法
JP2013083490A (ja) * 2011-10-06 2013-05-09 Kagoshima Univ 消化器癌診断用マーカー、および消化器癌の検査方法
US9810691B2 (en) 2011-10-11 2017-11-07 Board Of Regents, The University Of Texas System Biomarker for detecting cancer
KR101384211B1 (ko) * 2012-03-19 2014-04-14 서울대학교산학협력단 췌장암 진단용 마커 및 이의 용도
CN104142403B (zh) * 2013-05-10 2017-10-03 中国医学科学院北京协和医院 Chip蛋白在胰腺癌早期诊断以及预后判断中的用途
KR101582416B1 (ko) 2014-06-30 2016-01-06 가톨릭대학교 산학협력단 프로합토글로빈을 이용한 간암 진단방법
CN104678103A (zh) * 2014-08-05 2015-06-03 首都医科大学附属北京佑安医院 检测血清糖蛋白岩藻糖指数的化学发光蛋白芯片、试剂盒及检测方法
JP5996831B1 (ja) * 2015-02-27 2016-09-21 株式会社Ｊ−オイルミルズ シグナル増強剤
JP2019052092A (ja) * 2016-01-14 2019-04-04 株式会社Ｊ−オイルミルズ 合成スギタケレクチンの親和性を向上させる方法
JP7064121B2 (ja) * 2016-05-27 2022-05-10 富士フイルム和光純薬株式会社 消化器癌の判定方法
KR102095018B1 (ko) 2017-08-14 2020-03-30 중앙대학교 산학협력단 렉틴이 결합된 나노입자를 이용한 암 진단 방법
CN111551723A (zh) * 2020-06-01 2020-08-18 深圳格道糖生物技术有限公司 特定凝集素在基于唾液糖蛋白糖链结构鉴别胰腺癌方面的应用及相关产品
WO2022186318A1 (ja) * 2021-03-03 2022-09-09 株式会社先端生命科学研究所 がん検出方法、がん検査方法、及びこれらに用いるキット
US20240238318A1 (en) * 2021-05-06 2024-07-18 H. Lee Moffitt Cancer Center And Research Institute, Inc. L-fucose and anti-androgen receptor therapy for treatment of cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5358952B2 (ja) 2008-01-10 2013-12-04 和光純薬工業株式会社 膵臓癌マーカーおよび膵臓癌の検査方法
US8461305B2 (en) * 2008-07-22 2013-06-11 J-Oil Mills, Inc. L-fucose α1→6 specific lectin

Also Published As

Publication number Publication date
EP2498094B1 (en) 2016-02-24
KR101298579B1 (ko) 2013-08-22
KR20120130795A (ko) 2012-12-03
US20120244563A1 (en) 2012-09-27
US8481275B2 (en) 2013-07-09
CN103348247B (zh) 2015-08-12
RU2533219C2 (ru) 2014-11-20
RU2013105265A (ru) 2014-08-20
CN103348247A (zh) 2013-10-09
JP4900983B2 (ja) 2012-03-21
EP2498094A4 (en) 2012-12-05
WO2011089988A1 (ja) 2011-07-28
EP2498094A1 (en) 2012-09-12
JPWO2011089988A1 (ja) 2013-05-23

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