ES2554754T3 - Natalizumab para tratar enfermedades que necesitan tratamiento con esteroides - Google Patents
Natalizumab para tratar enfermedades que necesitan tratamiento con esteroides Download PDFInfo
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- ES2554754T3 ES2554754T3 ES05768245.2T ES05768245T ES2554754T3 ES 2554754 T3 ES2554754 T3 ES 2554754T3 ES 05768245 T ES05768245 T ES 05768245T ES 2554754 T3 ES2554754 T3 ES 2554754T3
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Transplantation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
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| US55812004P | 2004-04-01 | 2004-04-01 | |
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| PCT/US2005/010848 WO2005099776A2 (en) | 2004-04-01 | 2005-03-30 | Steroid sparing agents and methods of using same |
Publications (1)
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| ES2554754T3 true ES2554754T3 (es) | 2015-12-23 |
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| EP (1) | EP1734997B1 (enExample) |
| JP (2) | JP2007531761A (enExample) |
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| CA (1) | CA2561364C (enExample) |
| DK (1) | DK1734997T3 (enExample) |
| ES (1) | ES2554754T3 (enExample) |
| HU (1) | HUE026236T2 (enExample) |
| IL (1) | IL178302A (enExample) |
| MY (1) | MY162179A (enExample) |
| NO (1) | NO20064979L (enExample) |
| NZ (1) | NZ594476A (enExample) |
| PL (1) | PL1734997T3 (enExample) |
| PT (1) | PT1734997E (enExample) |
| SI (1) | SI1734997T1 (enExample) |
| TW (1) | TWI462744B (enExample) |
| WO (1) | WO2005099776A2 (enExample) |
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| WO2004071439A2 (en) | 2003-02-10 | 2004-08-26 | Elan Pharmaceuticals, Inc. | Immunoglobulin formulation and method of preparation thereof |
| MY162179A (en) | 2004-04-01 | 2017-05-31 | Elan Pharm Inc | Steroid sparing agents and methods of using same |
| JP2008520717A (ja) * | 2004-11-19 | 2008-06-19 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 多発性硬化症についての処置 |
| AU2012202575B2 (en) * | 2004-11-19 | 2014-11-20 | Biogen Ma Inc. | Treatment for Multiple Sclerosis |
| CA2662428A1 (en) * | 2006-09-13 | 2008-03-20 | The Procter & Gamble Company | Methods of treatment for ulcerative colitis |
| JP2008120722A (ja) * | 2006-11-10 | 2008-05-29 | Benesis Corp | 生物由来製品の偽薬 |
| WO2008125903A2 (en) * | 2006-12-12 | 2008-10-23 | Chaim Sheba Medical Center | Method of inhibiting an undesired immune response |
| CN109157742B (zh) | 2009-08-03 | 2022-04-05 | 因卡伯实验室有限责任公司 | 用于刺激肠道内肠促胰岛素产生的吞咽式囊和方法 |
| US8721620B2 (en) | 2009-12-24 | 2014-05-13 | Rani Therapeutics, Llc | Swallowable drug delivery device and methods of drug delivery |
| WO2011108638A1 (ja) * | 2010-03-04 | 2011-09-09 | 大日本住友製薬株式会社 | 炎症性腸疾患用薬剤 |
| EA201291065A1 (ru) | 2010-04-16 | 2013-03-29 | Байоджен Айдек Ма Инк. | Антитела против vla-4 |
| CA2805270C (en) * | 2010-06-04 | 2021-03-09 | The Brigham And Women's Hospital, Inc. | Treatment of inflammatory disorders |
| ES2654820T3 (es) | 2010-10-25 | 2018-02-15 | Biogen Ma Inc. | Métodos para determinar diferencias en la actividad de la alfa-4-integrina mediante la correlación de las diferencias en los niveles de sVCAM y/o sMAdCAM |
| US9402806B2 (en) | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10639272B2 (en) | 2010-12-23 | 2020-05-05 | Rani Therapeutics, Llc | Methods for delivering etanercept preparations into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8969293B2 (en) | 2010-12-23 | 2015-03-03 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising exenatide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9402807B2 (en) | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9283179B2 (en) | 2010-12-23 | 2016-03-15 | Rani Therapeutics, Llc | GnRH preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8809269B2 (en) | 2010-12-23 | 2014-08-19 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising insulin for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8846040B2 (en) | 2010-12-23 | 2014-09-30 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising etanercept for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9629799B2 (en) | 2010-12-23 | 2017-04-25 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8980822B2 (en) | 2010-12-23 | 2015-03-17 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising pramlintide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9861683B2 (en) | 2010-12-23 | 2018-01-09 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9284367B2 (en) * | 2010-12-23 | 2016-03-15 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9415004B2 (en) | 2010-12-23 | 2016-08-16 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8734429B2 (en) | 2010-12-23 | 2014-05-27 | Rani Therapeutics, Llc | Device, system and methods for the oral delivery of therapeutic compounds |
| US9259386B2 (en) | 2010-12-23 | 2016-02-16 | Rani Therapeutics, Llc | Therapeutic preparation comprising somatostatin or somatostatin analogoue for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| UA116189C2 (uk) * | 2011-05-02 | 2018-02-26 | Мілленніум Фармасьютікалз, Інк. | КОМПОЗИЦІЯ АНТИ-α4β7 АНТИТІЛА |
| US10040855B2 (en) | 2011-05-02 | 2018-08-07 | Millennium Pharmaceuticals, Inc. | Formulation for anti-α4β7 antibody |
| PT2543357T (pt) * | 2011-07-07 | 2018-04-30 | Holy Stone Healthcare Co Ltd | Resumo |
| WO2013078375A2 (en) * | 2011-11-23 | 2013-05-30 | Amgen Inc. | Administration of alpha4beta7 hetero-dimer-specific antibody |
| WO2016100301A1 (en) | 2014-12-15 | 2016-06-23 | The Brigham And Women's Hospital, Inc. | Use of cadherin-11 antagonists to treat obesity-associated conditions and other metabolic disorders |
| WO2016138538A2 (en) * | 2015-02-27 | 2016-09-01 | The General Hospital Corporation | Therapeutic use of integrin-binding antibodies |
| US12037398B2 (en) | 2018-06-04 | 2024-07-16 | Biogen Ma Inc. | Anti-VLA-4 antibodies having reduced effector function |
| AU2019287541A1 (en) * | 2018-06-14 | 2021-01-21 | Astrazeneca Uk Limited | Methods for treating and preventing symptoms of asthma with a corticosteroid pharmaceutical composition |
| US20230181714A1 (en) * | 2020-05-27 | 2023-06-15 | Vanderbilt University | Human monoclonal antibodies to venezuelan equine encephalitis virus and uses therefor |
| WO2024249568A1 (en) | 2023-05-30 | 2024-12-05 | Paragon Therapeutics, Inc. | Alpha4beta7 integrin antibody compositions and methods of use |
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| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| HUT35524A (en) | 1983-08-02 | 1985-07-29 | Hoechst Ag | Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| US6033665A (en) | 1989-09-27 | 2000-03-07 | Elan Pharmaceuticals, Inc. | Compositions and methods for modulating leukocyte adhesion to brain endothelial cells |
| DE122004000008I1 (de) | 1991-06-14 | 2005-06-09 | Genentech Inc | Humanisierter Heregulin Antikörper. |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| US5224539A (en) | 1991-06-14 | 1993-07-06 | Coen Company, Inc. | Cooling system for air heaters and the like |
| EP1136556B1 (en) | 1991-11-25 | 2005-06-08 | Enzon, Inc. | Method of producing multivalent antigen-binding proteins |
| US5840299A (en) | 1994-01-25 | 1998-11-24 | Athena Neurosciences, Inc. | Humanized antibodies against leukocyte adhesion molecule VLA-4 |
| AU2505599A (en) * | 1998-02-10 | 1999-08-30 | Cangene Corporation | Method for the prevention and treatment of a type i hypersensitivity disorder |
| AU6634501A (en) * | 2000-06-30 | 2002-01-14 | Sumitomo Pharma | Five-membered-ring compound |
| US6794506B2 (en) * | 2000-07-21 | 2004-09-21 | Elan Pharmaceuticals, Inc. | 3-(heteroaryl) alanine derivatives-inhibitors of leukocyte adhesion mediated by VLA-4 |
| US20020168360A1 (en) | 2001-03-02 | 2002-11-14 | Christine Dingivan | Methods of preventing or treating inflammatory or autoimmune disorders by administering integrin alphanubeta3 antagonists in combination with other prophylactic or therapeutic agents |
| CN1543345A (zh) * | 2001-05-09 | 2004-11-03 | 诺瓦提斯公司 | 使用匹美莫司进行选择性免疫调节的方法 |
| US20030008844A1 (en) * | 2001-05-17 | 2003-01-09 | Keryx Biopharmaceuticals, Inc. | Use of sulodexide for the treatment of inflammatory bowel disease |
| EP1436427B1 (en) * | 2001-10-19 | 2008-08-06 | Centre Hospitalier Régional et Universitaire de Tours | Methods and compositions to evaluate antibody treatment response |
| US6878518B2 (en) * | 2002-01-22 | 2005-04-12 | The Trustees Of The University Of Pennsylvania | Methods for determining steroid responsiveness |
| EP3674322A1 (en) | 2002-02-25 | 2020-07-01 | Biogen MA Inc. | Administration of agents for the treatment of inflammation |
| JP2006516624A (ja) | 2003-01-24 | 2006-07-06 | エラン ファーマシューティカルズ，インコーポレイテッド | 脱髄疾患および麻痺のための組成物ならびに再有髄化剤を投与することによるそれらの治療 |
| MY162179A (en) | 2004-04-01 | 2017-05-31 | Elan Pharm Inc | Steroid sparing agents and methods of using same |
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2005
- 2005-03-29 MY MYPI20051380A patent/MY162179A/en unknown
- 2005-03-30 EP EP05768245.2A patent/EP1734997B1/en not_active Revoked
- 2005-03-30 WO PCT/US2005/010848 patent/WO2005099776A2/en not_active Ceased
- 2005-03-30 CA CA2561364A patent/CA2561364C/en not_active Expired - Lifetime
- 2005-03-30 PT PT57682452T patent/PT1734997E/pt unknown
- 2005-03-30 HU HUE05768245A patent/HUE026236T2/en unknown
- 2005-03-30 NZ NZ594476A patent/NZ594476A/xx not_active IP Right Cessation
- 2005-03-30 JP JP2007506536A patent/JP2007531761A/ja active Pending
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- 2005-03-30 SI SI200532025T patent/SI1734997T1/sl unknown
- 2005-03-30 AU AU2005232571A patent/AU2005232571A1/en not_active Abandoned
- 2005-03-30 DK DK05768245.2T patent/DK1734997T3/en active
- 2005-03-31 TW TW094110385A patent/TWI462744B/zh not_active IP Right Cessation
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2006
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- 2006-10-31 NO NO20064979A patent/NO20064979L/no not_active Application Discontinuation
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2013
- 2013-04-08 JP JP2013080823A patent/JP2013166765A/ja active Pending
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2014
- 2014-07-28 US US14/444,862 patent/US20150056205A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005232571A1 (en) | 2005-10-27 |
| PT1734997E (pt) | 2015-12-22 |
| US20050260193A1 (en) | 2005-11-24 |
| MY162179A (en) | 2017-05-31 |
| NZ594476A (en) | 2013-04-26 |
| NO20064979L (no) | 2007-01-02 |
| JP2013166765A (ja) | 2013-08-29 |
| WO2005099776A9 (en) | 2005-12-01 |
| WO2005099776A2 (en) | 2005-10-27 |
| SI1734997T1 (sl) | 2016-02-29 |
| TWI462744B (zh) | 2014-12-01 |
| HK1102663A1 (zh) | 2007-11-30 |
| EP1734997B1 (en) | 2015-09-02 |
| DK1734997T3 (en) | 2015-11-30 |
| IL178302A (en) | 2016-03-31 |
| PL1734997T3 (pl) | 2016-02-29 |
| US20150056205A1 (en) | 2015-02-26 |
| CA2561364A1 (en) | 2005-10-27 |
| TW200602080A (en) | 2006-01-16 |
| HUE026236T2 (en) | 2016-06-28 |
| EP1734997A2 (en) | 2006-12-27 |
| IL178302A0 (en) | 2008-03-20 |
| CA2561364C (en) | 2016-11-08 |
| JP2007531761A (ja) | 2007-11-08 |
| WO2005099776A3 (en) | 2006-05-18 |
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