ES253961A1 - Procedimiento para la preparaciën de nuevos compuestos n-heterociclicos - Google Patents
Procedimiento para la preparaciën de nuevos compuestos n-heterociclicosInfo
- Publication number
- ES253961A1 ES253961A1 ES0253961A ES253961A ES253961A1 ES 253961 A1 ES253961 A1 ES 253961A1 ES 0253961 A ES0253961 A ES 0253961A ES 253961 A ES253961 A ES 253961A ES 253961 A1 ES253961 A1 ES 253961A1
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- general formula
- alkyl
- reacting
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 3 - chloro - 5 - (alpha - dimethylaminopropyl)-iminodibenzyl Chemical group 0.000 title abstract 3
- 239000002253 acid Substances 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 15
- 150000002148 esters Chemical class 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract 2
- 150000001339 alkali metal compounds Chemical class 0.000 abstract 2
- 125000005277 alkyl imino group Chemical group 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- KZNICNPSHKQLFF-UHFFFAOYSA-N succinimide Chemical compound O=C1CCC(=O)N1 KZNICNPSHKQLFF-UHFFFAOYSA-N 0.000 abstract 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- MHUXTOYYIDFXRF-UHFFFAOYSA-N 2-chloro-6,11-dihydro-5h-benzo[b][1]benzazepine Chemical group C1CC2=CC=CC=C2NC2=CC(Cl)=CC=C21 MHUXTOYYIDFXRF-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 abstract 1
- MFESCIUQSIBMSM-UHFFFAOYSA-N I-BCP Chemical compound ClCCCBr MFESCIUQSIBMSM-UHFFFAOYSA-N 0.000 abstract 1
- YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 abstract 1
- 150000001335 aliphatic alkanes Chemical class 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000004391 aryl sulfonyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229910002092 carbon dioxide Inorganic materials 0.000 abstract 1
- 239000001569 carbon dioxide Substances 0.000 abstract 1
- 229910002091 carbon monoxide Inorganic materials 0.000 abstract 1
- 150000001735 carboxylic acids Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000004966 cyanoalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 229910052987 metal hydride Inorganic materials 0.000 abstract 1
- 150000004681 metal hydrides Chemical class 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- KNCYXPMJDCCGSJ-UHFFFAOYSA-N piperidine-2,6-dione Chemical compound O=C1CCCC(=O)N1 KNCYXPMJDCCGSJ-UHFFFAOYSA-N 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003856 quaternary ammonium compounds Chemical class 0.000 abstract 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 1
- 150000003335 secondary amines Chemical class 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 229960002317 succinimide Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH6704958A CH371799A (de) | 1958-12-06 | 1958-12-06 | Verfahren zur Herstellung von neuen N-heterocyclischen Verbindungen |
| CH6704658A CH370082A (de) | 1958-12-06 | 1958-12-06 | Verfahren zur Herstellung von neuen N-heterocyclischen Verbindungen |
| CH6820159A CH371800A (de) | 1959-01-12 | 1959-01-12 | Verfahren zur Herstellung von neuen N-heterocyclischen Verbindungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES253961A1 true ES253961A1 (es) | 1960-05-16 |
Family
ID=27178525
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0253961A Expired ES253961A1 (es) | 1958-12-06 | 1959-12-05 | Procedimiento para la preparaciën de nuevos compuestos n-heterociclicos |
| ES0253960A Expired ES253960A1 (es) | 1958-12-06 | 1959-12-05 | Procedimiento para la preparaciën de nuevos compuestos n-heterociclicos |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0253960A Expired ES253960A1 (es) | 1958-12-06 | 1959-12-05 | Procedimiento para la preparaciën de nuevos compuestos n-heterociclicos |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3467650A (enrdf_load_html_response) |
| BE (1) | BE585367A (enrdf_load_html_response) |
| CY (1) | CY334A (enrdf_load_html_response) |
| ES (2) | ES253961A1 (enrdf_load_html_response) |
| FR (1) | FR278M (enrdf_load_html_response) |
| GB (1) | GB934630A (enrdf_load_html_response) |
| NL (1) | NL110232C (enrdf_load_html_response) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3886170A (en) * | 1974-04-22 | 1975-05-27 | Robins Co Inc A H | 5-(3-)SUBSTITUTED-10,11-DIHYDRO-5H-dibenz{8 b,f{9 azepines |
| US4017621A (en) * | 1974-12-09 | 1977-04-12 | Sumitomo Chemical Company, Limited | 2-Morpholinyl tricyclic dibenzazepine compounds |
| US6495154B1 (en) | 2000-11-21 | 2002-12-17 | Vivus Inc. | On demand administration of clomipramine and salts thereof to treat premature ejaculation |
| ES2515092T3 (es) | 2003-12-11 | 2014-10-29 | Sunovion Pharmaceuticals Inc. | Combinación de un sedante y un modulador neurotransmisor y métodos de mejorar la calidad del sueño y de tratar la depresión |
| BRPI0618643A2 (pt) | 2005-11-09 | 2011-09-06 | Combinatorx Inc | composição compreendendo um par de fármacos, composição compreendendo um corticosteróide e um imunossupressor dependente de imunofilina não-esteróide, kits e uso |
| ES2534589T3 (es) | 2007-04-13 | 2015-04-24 | Southern Research Institute | Clomipramina como agente antiangiogénico |
| MX2010005813A (es) | 2007-11-28 | 2010-06-15 | Nektar Therapeutics | Conjugados oligomero-triciclicos. |
| WO2011091050A1 (en) | 2010-01-19 | 2011-07-28 | Nektar Therapeutics | Oligomer-tricyclic conjugates |
| US9090535B2 (en) | 2010-12-10 | 2015-07-28 | Nektar Therapeutics | Hydroxylated tricyclic compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2813857A (en) * | 1957-11-19 | N-aminoalkylated substituted iminodi- | ||
| AT200578B (de) * | 1956-11-13 | 1958-11-10 | Geigy Ag J R | Verfahren zur Herstellung von neuen N-Aminoalkylderivaten von Azepinen |
-
0
- NL NL110232D patent/NL110232C/xx active
-
1959
- 1959-12-04 GB GB41190/59A patent/GB934630A/en not_active Expired
- 1959-12-04 US US857274A patent/US3467650A/en not_active Expired - Lifetime
- 1959-12-05 ES ES0253961A patent/ES253961A1/es not_active Expired
- 1959-12-05 ES ES0253960A patent/ES253960A1/es not_active Expired
- 1959-12-07 BE BE585367A patent/BE585367A/fr unknown
-
1960
- 1960-08-24 FR FR836637A patent/FR278M/fr active Active
-
1965
- 1965-12-21 CY CY33465A patent/CY334A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES253960A1 (es) | 1960-05-16 |
| FR278M (fr) | 1961-03-13 |
| CY334A (en) | 1965-12-21 |
| US3467650A (en) | 1969-09-16 |
| NL110232C (enrdf_load_html_response) | |
| GB934630A (en) | 1963-08-21 |
| BE585367A (fr) | 1960-06-07 |
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