ES2534543T3 - Soluciones enzimáticas estables y método de fabricación - Google Patents
Soluciones enzimáticas estables y método de fabricación Download PDFInfo
- Publication number
- ES2534543T3 ES2534543T3 ES08718284.6T ES08718284T ES2534543T3 ES 2534543 T3 ES2534543 T3 ES 2534543T3 ES 08718284 T ES08718284 T ES 08718284T ES 2534543 T3 ES2534543 T3 ES 2534543T3
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- ES
- Spain
- Prior art keywords
- salt
- constituent
- enzyme
- boronic acid
- composition
- Prior art date
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- 102000004190 Enzymes Human genes 0.000 title claims description 85
- 108090000790 Enzymes Proteins 0.000 title claims description 85
- 238000004519 manufacturing process Methods 0.000 title claims description 7
- 239000000203 mixture Substances 0.000 claims abstract description 89
- 239000007788 liquid Substances 0.000 claims abstract description 64
- 150000003839 salts Chemical class 0.000 claims abstract description 54
- 239000000470 constituent Substances 0.000 claims abstract description 45
- HXITXNWTGFUOAU-UHFFFAOYSA-N phenylboronic acid Chemical compound OB(O)C1=CC=CC=C1 HXITXNWTGFUOAU-UHFFFAOYSA-N 0.000 claims abstract description 42
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 claims abstract description 23
- 229910002651 NO3 Inorganic materials 0.000 claims abstract description 22
- 230000002255 enzymatic effect Effects 0.000 claims abstract description 11
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims abstract description 8
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims abstract description 8
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims abstract description 6
- 150000001450 anions Chemical class 0.000 claims abstract description 6
- 108091005804 Peptidases Proteins 0.000 claims description 33
- 239000004365 Protease Substances 0.000 claims description 28
- 102000012479 Serine Proteases Human genes 0.000 claims description 15
- 108010022999 Serine Proteases Proteins 0.000 claims description 15
- 229910052708 sodium Inorganic materials 0.000 claims description 14
- 150000001768 cations Chemical class 0.000 claims description 12
- 229910052749 magnesium Inorganic materials 0.000 claims description 11
- 229910052725 zinc Inorganic materials 0.000 claims description 10
- 229910052700 potassium Inorganic materials 0.000 claims description 7
- 229910052791 calcium Inorganic materials 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 5
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims description 3
- 239000001257 hydrogen Substances 0.000 claims description 3
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- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 3
- 230000002401 inhibitory effect Effects 0.000 claims description 3
- 230000008569 process Effects 0.000 claims description 3
- 125000006727 (C1-C6) alkenyl group Chemical group 0.000 claims description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 2
- 125000005017 substituted alkenyl group Chemical group 0.000 claims description 2
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- 239000011777 magnesium Substances 0.000 description 17
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- 239000011734 sodium Substances 0.000 description 12
- VWDWKYIASSYTQR-UHFFFAOYSA-N sodium nitrate Chemical compound [Na+].[O-][N+]([O-])=O VWDWKYIASSYTQR-UHFFFAOYSA-N 0.000 description 12
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 10
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 description 10
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- 229910000368 zinc sulfate Inorganic materials 0.000 description 7
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
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- 230000001580 bacterial effect Effects 0.000 description 6
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- JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical compound [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 description 6
- 239000011686 zinc sulphate Substances 0.000 description 6
- 235000009529 zinc sulphate Nutrition 0.000 description 6
- VXWBQOJISHAKKM-UHFFFAOYSA-N (4-formylphenyl)boronic acid Chemical group OB(O)C1=CC=C(C=O)C=C1 VXWBQOJISHAKKM-UHFFFAOYSA-N 0.000 description 5
- 108010011619 6-Phytase Proteins 0.000 description 5
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- ZADPBFCGQRWHPN-UHFFFAOYSA-N boronic acid Chemical compound OBO ZADPBFCGQRWHPN-UHFFFAOYSA-N 0.000 description 5
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- 239000000460 chlorine Substances 0.000 description 5
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- 239000000243 solution Substances 0.000 description 5
- 239000011592 zinc chloride Substances 0.000 description 5
- 235000005074 zinc chloride Nutrition 0.000 description 5
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 4
- 241000193830 Bacillus <bacterium> Species 0.000 description 4
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- 108700020962 Peroxidase Proteins 0.000 description 4
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 4
- 150000001413 amino acids Chemical group 0.000 description 4
- 239000007864 aqueous solution Substances 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 125000005620 boronic acid group Chemical class 0.000 description 4
- 239000011575 calcium Substances 0.000 description 4
- 150000001720 carbohydrates Chemical class 0.000 description 4
- 235000014113 dietary fatty acids Nutrition 0.000 description 4
- 239000000194 fatty acid Substances 0.000 description 4
- 229930195729 fatty acid Natural products 0.000 description 4
- 239000006260 foam Substances 0.000 description 4
- KVCGISUBCHHTDD-UHFFFAOYSA-M sodium;4-methylbenzenesulfonate Chemical compound [Na+].CC1=CC=C(S([O-])(=O)=O)C=C1 KVCGISUBCHHTDD-UHFFFAOYSA-M 0.000 description 4
- 239000000758 substrate Substances 0.000 description 4
- 238000012546 transfer Methods 0.000 description 4
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 3
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 3
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 3
- 108010001682 Dextranase Proteins 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 241000589516 Pseudomonas Species 0.000 description 3
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 3
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- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 3
- 229910052794 bromium Inorganic materials 0.000 description 3
- 239000001110 calcium chloride Substances 0.000 description 3
- 229910001628 calcium chloride Inorganic materials 0.000 description 3
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- 229910052801 chlorine Inorganic materials 0.000 description 3
- 108010005400 cutinase Proteins 0.000 description 3
- 239000002532 enzyme inhibitor Substances 0.000 description 3
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- 108010003855 mesentericopeptidase Proteins 0.000 description 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 3
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- 229920006395 saturated elastomer Polymers 0.000 description 3
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- 235000011152 sodium sulphate Nutrition 0.000 description 3
- QUCDWLYKDRVKMI-UHFFFAOYSA-M sodium;3,4-dimethylbenzenesulfonate Chemical compound [Na+].CC1=CC=C(S([O-])(=O)=O)C=C1C QUCDWLYKDRVKMI-UHFFFAOYSA-M 0.000 description 3
- FRPJTGXMTIIFIT-UHFFFAOYSA-N tetraacetylethylenediamine Chemical compound CC(=O)C(N)(C(C)=O)C(N)(C(C)=O)C(C)=O FRPJTGXMTIIFIT-UHFFFAOYSA-N 0.000 description 3
- DKYRKAIKWFHQHM-UHFFFAOYSA-N (3,5-dichlorophenyl)boronic acid Chemical compound OB(O)C1=CC(Cl)=CC(Cl)=C1 DKYRKAIKWFHQHM-UHFFFAOYSA-N 0.000 description 2
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- YASYEJJMZJALEJ-UHFFFAOYSA-N Citric acid monohydrate Chemical compound O.OC(=O)CC(O)(C(O)=O)CC(O)=O YASYEJJMZJALEJ-UHFFFAOYSA-N 0.000 description 2
- 241000242346 Constrictibacter antarcticus Species 0.000 description 2
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- YRIZYWQGELRKNT-UHFFFAOYSA-N 1,3,5-trichloro-1,3,5-triazinane-2,4,6-trione Chemical class ClN1C(=O)N(Cl)C(=O)N(Cl)C1=O YRIZYWQGELRKNT-UHFFFAOYSA-N 0.000 description 1
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- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- HLBBKKJFGFRGMU-UHFFFAOYSA-M sodium formate Chemical compound [Na+].[O-]C=O HLBBKKJFGFRGMU-UHFFFAOYSA-M 0.000 description 1
- 235000019254 sodium formate Nutrition 0.000 description 1
- 239000004317 sodium nitrate Substances 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 229910000162 sodium phosphate Inorganic materials 0.000 description 1
- 235000011008 sodium phosphates Nutrition 0.000 description 1
- CRWJEUDFKNYSBX-UHFFFAOYSA-N sodium;hypobromite Chemical compound [Na+].Br[O-] CRWJEUDFKNYSBX-UHFFFAOYSA-N 0.000 description 1
- MWNQXXOSWHCCOZ-UHFFFAOYSA-L sodium;oxido carbonate Chemical compound [Na+].[O-]OC([O-])=O MWNQXXOSWHCCOZ-UHFFFAOYSA-L 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000005846 sugar alcohols Chemical class 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
- 150000003457 sulfones Chemical class 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 150000004685 tetrahydrates Chemical class 0.000 description 1
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- ARYHTUPFQTUBBG-UHFFFAOYSA-N thiophen-2-ylboronic acid Chemical compound OB(O)C1=CC=CS1 ARYHTUPFQTUBBG-UHFFFAOYSA-N 0.000 description 1
- QNMBSXGYAQZCTN-UHFFFAOYSA-N thiophen-3-ylboronic acid Chemical compound OB(O)C=1C=CSC=1 QNMBSXGYAQZCTN-UHFFFAOYSA-N 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- 239000001226 triphosphate Substances 0.000 description 1
- 235000011178 triphosphate Nutrition 0.000 description 1
- UNXRWKVEANCORM-UHFFFAOYSA-N triphosphoric acid Chemical compound OP(O)(=O)OP(O)(=O)OP(O)(O)=O UNXRWKVEANCORM-UHFFFAOYSA-N 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 229920001221 xylan Polymers 0.000 description 1
- 150000004823 xylans Chemical class 0.000 description 1
- 150000003751 zinc Chemical class 0.000 description 1
- 229960001763 zinc sulfate Drugs 0.000 description 1
- RZLVQBNCHSJZPX-UHFFFAOYSA-L zinc sulfate heptahydrate Chemical compound O.O.O.O.O.O.O.[Zn+2].[O-]S([O-])(=O)=O RZLVQBNCHSJZPX-UHFFFAOYSA-L 0.000 description 1
- 239000004711 α-olefin Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38663—Stabilised liquid enzyme compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/02—Inorganic compounds ; Elemental compounds
- C11D3/04—Water-soluble compounds
- C11D3/046—Salts
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/02—Inorganic compounds ; Elemental compounds
- C11D3/04—Water-soluble compounds
- C11D3/046—Salts
- C11D3/048—Nitrates or nitrites
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/166—Organic compounds containing borium
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/2075—Carboxylic acids-salts thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Detergent Compositions (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK200700472 | 2007-03-27 | ||
| DKPA200700472 | 2007-03-27 | ||
| PCT/EP2008/053660 WO2008116915A1 (en) | 2007-03-27 | 2008-03-27 | Stable enzyme solutions and method of manufacturing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2534543T3 true ES2534543T3 (es) | 2015-04-24 |
Family
ID=38480677
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES08718284.6T Active ES2534543T3 (es) | 2007-03-27 | 2008-03-27 | Soluciones enzimáticas estables y método de fabricación |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10590368B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2139979B1 (cg-RX-API-DMAC7.html) |
| JP (3) | JP5718636B2 (cg-RX-API-DMAC7.html) |
| CN (2) | CN103865682B (cg-RX-API-DMAC7.html) |
| DK (1) | DK2139979T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2534543T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008116915A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5718636B2 (ja) * | 2007-03-27 | 2015-05-13 | ノボザイムス アクティーゼルスカブ | 安定な酵素溶液及び製造方法 |
| FI121711B (fi) * | 2009-04-30 | 2011-03-15 | Ab Enzymes Oy | Sieniperäinen seriiniproteaasi ja sen käyttö |
| FI121712B (fi) * | 2009-04-30 | 2011-03-15 | Ab Enzymes Oy | Uusi sieniperäinen proteaasi ja sen käyttö |
| FI121851B (fi) * | 2009-07-08 | 2011-05-13 | Ab Enzymes Oy | Sieniperäinen proteaasi ja sen käyttö |
| DE102010038497A1 (de) * | 2010-07-27 | 2012-02-02 | Henkel Ag & Co. Kgaa | Stabilisierte flüssige enzymhaltige Tensidzubereitung |
| FI123942B (fi) | 2010-10-29 | 2013-12-31 | Ab Enzymes Oy | Sieniperäisen seriiniproteaasin variantteja |
| DK177132B1 (da) | 2010-11-05 | 2012-01-30 | Respekt Danmark As | Maskinopvask |
| FI123425B (fi) | 2011-03-31 | 2013-04-30 | Ab Enzymes Oy | Proteaasientsyymi ja sen käytöt |
| EP2737043B1 (en) | 2011-07-25 | 2017-01-04 | The Procter and Gamble Company | Detergents having acceptable color |
| EP2716644B1 (en) | 2012-10-03 | 2017-04-05 | The Procter and Gamble Company | A stable enzyme stabilizer premix |
| WO2016001319A1 (en) * | 2014-07-03 | 2016-01-07 | Novozymes A/S | Improved stabilization of non-protease enzyme |
| JP2019536879A (ja) * | 2016-12-01 | 2019-12-19 | ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ | 組成物中の酵素の安定化 |
| CN107043762A (zh) * | 2017-04-21 | 2017-08-15 | 江苏福隆生物技术有限公司 | 一种提高辣根过氧化物酶保存稳定性的保存稳定剂及其保存方法 |
| EP3728535B1 (en) * | 2017-12-20 | 2023-10-25 | Basf Se | Laundry formulation for removing fatty compounds having a melting temperature > 30°c deposited on textiles |
| EP3636735B1 (en) | 2018-10-12 | 2024-03-27 | AB Enzymes Oy | Protease enzyme variants and uses thereof |
| WO2021089750A1 (en) * | 2019-11-08 | 2021-05-14 | Novozymes A/S | Stabilized liquid enzyme compositions for brewing |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE68923398T2 (de) * | 1988-05-12 | 1996-01-25 | Procter & Gamble | Flüssige Universalwaschmittel, welche anionische und nichtionische oberflächenaktive Mittel, Gerüststoffe und proteolytisches Enzym enthalten. |
| EP0481542A3 (en) | 1990-10-04 | 1992-07-29 | Unilever Nv | Stabilized enzymatic aqueous detergent compositions |
| EP0511456A1 (en) * | 1991-04-30 | 1992-11-04 | The Procter & Gamble Company | Liquid detergents with aromatic borate ester to inhibit proteolytic enzyme |
| CA2109526C (en) * | 1991-04-30 | 1998-01-20 | Dwight M. Peterson | Liquid detergents with an aryl boroic acid |
| US5691292A (en) * | 1992-04-13 | 1997-11-25 | The Procter & Gamble Company | Thixotropic liquid automatic dishwashing composition with enzyme |
| US5998350A (en) * | 1993-05-20 | 1999-12-07 | The Procter & Gamble Company | Bleaching compounds comprising N-acyl caprolactam and/or peroxy acid activators |
| AU7051094A (en) | 1993-06-14 | 1995-01-03 | Procter & Gamble Company, The | Concentrated nil-phosphate liquid automatic dishwashing detergent compositions containing enzyme |
| CN1127014A (zh) | 1993-07-09 | 1996-07-17 | 诺沃挪第克公司 | 作为酶稳定剂的一烃基硼酸或二烃基硼酸衍生物 |
| US5431842A (en) * | 1993-11-05 | 1995-07-11 | The Procter & Gamble Company | Liquid detergents with ortho-substituted phenylboronic acids for inhibition of proteolytic enzyme |
| US5510052A (en) | 1994-08-25 | 1996-04-23 | Colgate-Palmolive Co. | Enzymatic aqueous pretreatment composition for dishware |
| AU4328396A (en) * | 1995-01-09 | 1996-07-31 | Novo Nordisk A/S | Stabilization of liquid enzyme compositions |
| AU6188096A (en) * | 1995-06-13 | 1997-01-09 | Novo Nordisk A/S | 4-substituted-phenyl-boronic acids as enzyme stabilizers |
| US6093856A (en) | 1996-11-26 | 2000-07-25 | The Procter & Gamble Company | Polyoxyalkylene surfactants |
| WO1998028392A1 (en) * | 1996-12-20 | 1998-07-02 | The Procter & Gamble Company | Dishwashing detergent compositions containing alkanolamine |
| JP4322362B2 (ja) * | 1999-08-03 | 2009-08-26 | 花王株式会社 | 液体洗剤 |
| US6673763B1 (en) * | 1999-09-24 | 2004-01-06 | Novozymes A/S | Particles for liquid compositions |
| JP2001157581A (ja) | 1999-12-02 | 2001-06-12 | Kao Corp | 複合酵素粒剤の製造法 |
| ES2208611T3 (es) | 2000-06-15 | 2004-06-16 | Unilever N.V. | Composicion de detergente liquido concentrado. |
| DE60139999D1 (de) | 2000-07-22 | 2009-11-05 | Genencor Int | Enzymstabilisierung |
| GB2367065B (en) | 2000-09-20 | 2002-11-20 | Reckitt Benckiser Inc | Enzyme containing laundry booster compositions |
| US20030109406A1 (en) | 2001-07-03 | 2003-06-12 | Cooney Edward M. | Storage stable concentrated cleaning solution |
| MXPA04004479A (es) * | 2001-11-13 | 2004-08-11 | Procter & Gamble | Composiciones topicas que contienen enzimas estabilizadas con inhibidores. |
| GB0207430D0 (en) | 2002-03-28 | 2002-05-08 | Unilever Plc | Liquid cleaning compositionsand their use |
| US7425528B2 (en) * | 2002-07-01 | 2008-09-16 | Novozymes A/S | Stabilization of granules |
| KR20040008986A (ko) * | 2002-07-20 | 2004-01-31 | 씨제이 주식회사 | 알칼리성 액체 세제 조성물 |
| DE10237317B4 (de) | 2002-08-15 | 2010-04-08 | 3M Espe Ag | Enzymhaltige Zusammensetzung, Verfahren zu deren Herstellung und deren Verwendung |
| EP1597344A2 (en) * | 2003-02-18 | 2005-11-23 | Novozymes A/S | Detergent compositions |
| US7226900B2 (en) | 2003-06-16 | 2007-06-05 | The Proctor & Gamble Company | Liquid laundry detergent composition containing boron-compatible cationic deposition aids |
| EP1924677A1 (en) | 2005-09-02 | 2008-05-28 | Novozymes A/S | Stabilization of concentrated liquid enzyme additives |
| US20070060493A1 (en) * | 2005-09-02 | 2007-03-15 | Novozymes A/S | Stabilization of concentrated liquid enzyme additives |
| US20070111914A1 (en) * | 2005-11-16 | 2007-05-17 | Conopco, Inc., D/B/A Unilever, A Corporation Of New York | Environmentally friendly laundry method and kit |
| US20070179074A1 (en) * | 2006-01-23 | 2007-08-02 | Souter Philip F | Detergent compositions |
| JP2010501024A (ja) * | 2006-06-05 | 2010-01-14 | ザ プロクター アンド ギャンブル カンパニー | 酵素安定剤 |
| US20080268229A1 (en) | 2006-08-09 | 2008-10-30 | Daeyeon Lee | Superhydrophilic coatings |
| JP5718636B2 (ja) * | 2007-03-27 | 2015-05-13 | ノボザイムス アクティーゼルスカブ | 安定な酵素溶液及び製造方法 |
-
2008
- 2008-03-27 JP JP2010500277A patent/JP5718636B2/ja not_active Ceased
- 2008-03-27 ES ES08718284.6T patent/ES2534543T3/es active Active
- 2008-03-27 CN CN201410082917.0A patent/CN103865682B/zh active Active
- 2008-03-27 CN CN200880010193.1A patent/CN101646760B/zh active Active
- 2008-03-27 EP EP08718284.6A patent/EP2139979B1/en not_active Revoked
- 2008-03-27 US US12/530,968 patent/US10590368B2/en active Active
- 2008-03-27 WO PCT/EP2008/053660 patent/WO2008116915A1/en not_active Ceased
- 2008-03-27 DK DK08718284.6T patent/DK2139979T3/en active
-
2014
- 2014-09-16 JP JP2014187988A patent/JP6212010B2/ja not_active Ceased
-
2017
- 2017-09-14 JP JP2017176944A patent/JP6927817B2/ja active Active
-
2020
- 2020-02-12 US US16/789,252 patent/US11827866B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2139979A1 (en) | 2010-01-06 |
| US20100120649A1 (en) | 2010-05-13 |
| CN101646760B (zh) | 2014-11-26 |
| JP2015042747A (ja) | 2015-03-05 |
| WO2008116915A1 (en) | 2008-10-02 |
| CN103865682B (zh) | 2017-04-26 |
| JP6212010B2 (ja) | 2017-10-11 |
| US11827866B2 (en) | 2023-11-28 |
| CN103865682A (zh) | 2014-06-18 |
| US10590368B2 (en) | 2020-03-17 |
| CN101646760A (zh) | 2010-02-10 |
| JP2017222882A (ja) | 2017-12-21 |
| JP6927817B2 (ja) | 2021-09-01 |
| DK2139979T3 (en) | 2015-05-26 |
| JP5718636B2 (ja) | 2015-05-13 |
| JP2010522791A (ja) | 2010-07-08 |
| US20200181541A1 (en) | 2020-06-11 |
| EP2139979B1 (en) | 2015-02-25 |
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