ES2532404T3 - Métodos para tratar la esclerosis múltiple usando oligonucleótidos antisentido - Google Patents
Métodos para tratar la esclerosis múltiple usando oligonucleótidos antisentido Download PDFInfo
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- ES2532404T3 ES2532404T3 ES09798248.2T ES09798248T ES2532404T3 ES 2532404 T3 ES2532404 T3 ES 2532404T3 ES 09798248 T ES09798248 T ES 09798248T ES 2532404 T3 ES2532404 T3 ES 2532404T3
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- C12N2310/11—Antisense
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- C12N2310/32—Chemical structure of the sugar
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- C12N2310/33—Chemical structure of the base
- C12N2310/334—Modified C
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- C12N2310/34—Spatial arrangement of the modifications
- C12N2310/341—Gapmers, i.e. of the type ===---===
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- Zoology (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US13297308P | 2008-06-23 | 2008-06-23 | |
| US132973P | 2008-06-23 | ||
| PCT/US2009/003760 WO2010008474A2 (en) | 2008-06-23 | 2009-06-23 | Methods for treating multiple sclerosis using antisense oligonucleotides |
Publications (1)
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| ES2532404T3 true ES2532404T3 (es) | 2015-03-26 |
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| ES15155831T Active ES2699891T3 (es) | 2008-06-23 | 2009-06-23 | Métodos para tratar la esclerosis múltiple usando oligonucleótidos antisentido |
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| ES15155831T Active ES2699891T3 (es) | 2008-06-23 | 2009-06-23 | Métodos para tratar la esclerosis múltiple usando oligonucleótidos antisentido |
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| WO (1) | WO2010008474A2 (enExample) |
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| ES2532404T3 (es) | 2008-06-23 | 2015-03-26 | Antisense Therapeutics Ltd | Métodos para tratar la esclerosis múltiple usando oligonucleótidos antisentido |
| AU2011301712C1 (en) * | 2010-09-17 | 2017-01-05 | Antisense Therapeutics Ltd | Method for reducing the number of certain circulating leukocytes in a human subject |
| EP3294889B1 (en) * | 2015-05-11 | 2021-01-06 | Murdoch University | Multiple sclerosis treatment |
| AU2018286483C1 (en) * | 2017-06-16 | 2024-10-31 | Antisense Therapeutics Ltd | Methods for treating multiple sclerosis using antisense oligonucleotides |
| KR20210018820A (ko) * | 2018-05-04 | 2021-02-18 | 안티센스 테라퓨틱스 엘티디 | 치료 용도 및 방법 |
| WO2020223762A1 (en) * | 2019-05-06 | 2020-11-12 | Antisense Therapeutics Ltd | Methods for treating muscular dystrophy using inhibitory oligonucleotides to cd49d |
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| US6242591B1 (en) * | 1997-10-15 | 2001-06-05 | Isis Pharmaceuticals, Inc. | Synthesis of sulfurized 2'-substituted oligonucleotides |
| US5968826A (en) * | 1998-10-05 | 1999-10-19 | Isis Pharmaceuticals Inc. | Antisense inhibition of integrin α4 expression |
| WO2005108610A2 (en) * | 2004-04-05 | 2005-11-17 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Methods for the selection of subjects for multiple sclerosis therapy |
| JP2008516991A (ja) * | 2004-10-20 | 2008-05-22 | アンチセンス セラピューティクス リミテッド | インテグリンα４発現のアンチセンス調節 |
| ES2532404T3 (es) | 2008-06-23 | 2015-03-26 | Antisense Therapeutics Ltd | Métodos para tratar la esclerosis múltiple usando oligonucleótidos antisentido |
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2014
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Also Published As
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| JP2015044824A (ja) | 2015-03-12 |
| EP2318424B1 (en) | 2015-02-25 |
| DK2937358T3 (da) | 2019-01-02 |
| AU2009271678B2 (en) | 2013-09-19 |
| EP2318424A4 (en) | 2012-12-26 |
| JP6131230B2 (ja) | 2017-05-17 |
| WO2010008474A2 (en) | 2010-01-21 |
| JP2011525531A (ja) | 2011-09-22 |
| WO2010008474A3 (en) | 2010-04-22 |
| AU2009271678A1 (en) | 2010-01-21 |
| US8415314B2 (en) | 2013-04-09 |
| DK2318424T3 (en) | 2015-04-07 |
| WO2010008474A4 (en) | 2011-01-27 |
| EP2937358B1 (en) | 2018-09-19 |
| JP5988581B2 (ja) | 2016-09-07 |
| US20100119480A1 (en) | 2010-05-13 |
| EP2937358A1 (en) | 2015-10-28 |
| CA2728562C (en) | 2018-10-23 |
| US20130345293A1 (en) | 2013-12-26 |
| CA2728562A1 (en) | 2010-01-21 |
| ES2699891T3 (es) | 2019-02-13 |
| EP2318424A2 (en) | 2011-05-11 |
| US8759314B2 (en) | 2014-06-24 |
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