ES2531955T3 - Soluciones estériles de ácido hialurónico - Google Patents

Soluciones estériles de ácido hialurónico Download PDF

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Publication number
ES2531955T3
ES2531955T3 ES11702563.5T ES11702563T ES2531955T3 ES 2531955 T3 ES2531955 T3 ES 2531955T3 ES 11702563 T ES11702563 T ES 11702563T ES 2531955 T3 ES2531955 T3 ES 2531955T3
Authority
ES
Spain
Prior art keywords
hyaluronic acid
solution
weight
saline
filtration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES11702563.5T
Other languages
English (en)
Spanish (es)
Inventor
Xiaojun Michael Liu
David Joseph Heiler
Thomas Menzel
Abbie BRONGO
Susan E. Burke
Karl Cummins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bausch and Lomb Inc
Original Assignee
Bausch and Lomb Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bausch and Lomb Inc filed Critical Bausch and Lomb Inc
Application granted granted Critical
Publication of ES2531955T3 publication Critical patent/ES2531955T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/022—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
ES11702563.5T 2010-02-09 2011-01-27 Soluciones estériles de ácido hialurónico Active ES2531955T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US702540 2000-10-31
US12/702,540 US8283463B2 (en) 2010-02-09 2010-02-09 Sterile hyaluronic acid solutions
PCT/US2011/022656 WO2011100114A1 (en) 2010-02-09 2011-01-27 Sterile hyaluronic acid solutions

Publications (1)

Publication Number Publication Date
ES2531955T3 true ES2531955T3 (es) 2015-03-23

Family

ID=43754892

Family Applications (1)

Application Number Title Priority Date Filing Date
ES11702563.5T Active ES2531955T3 (es) 2010-02-09 2011-01-27 Soluciones estériles de ácido hialurónico

Country Status (8)

Country Link
US (2) US8283463B2 (https=)
EP (2) EP2865395A1 (https=)
JP (1) JP5789271B2 (https=)
BR (1) BR112012019008B8 (https=)
ES (1) ES2531955T3 (https=)
PL (1) PL2400993T3 (https=)
TW (1) TWI405595B (https=)
WO (1) WO2011100114A1 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011140519A2 (en) 2010-05-07 2011-11-10 Medicus Biosciences, Llc In vivo gelling pharmaceutical pre-formulation
EP2606828B1 (en) * 2011-12-20 2018-04-11 Angioclinic AG Hyaluronic acid and its use for treating venous insufficiency and varicose veins
US10111985B2 (en) * 2011-08-10 2018-10-30 Medicus Biosciences, Llc Biocompatible hydrogel polymer formulations for the controlled delivery of biomolecules
US11083821B2 (en) * 2011-08-10 2021-08-10 C.P. Medical Corporation Biocompatible hydrogel polymer formulations for the controlled delivery of biomolecules
JP6206987B2 (ja) 2012-05-11 2017-10-04 メディカス バイオサイエンシーズ，エルエルシー 網膜剥離の処置のための生体適合性ヒドロゲル製剤
FR3019465B1 (fr) 2014-04-02 2017-06-23 Horus Pharma Composition hyperosmolaire d'acide hyaluronique et son utilisation pour le traitement de l'oedeme corneen
EP3741351A1 (en) 2014-04-17 2020-11-25 Merz Pharma GmbH & Co. KGaA Composition for improving the appearance of ageing skin
US10245324B2 (en) 2014-10-31 2019-04-02 Johnson & Johnson Consumer Inc. Ophthalmic composition
US20170014339A1 (en) * 2015-07-17 2017-01-19 i.com medical GmbH Tear Substitute, Fluid for Being Used as a Tear Substitute, and Method for Producing a Tear Substitute
DE102015226456A1 (de) 2015-12-22 2017-06-22 Heraeus Medical Gmbh Verfahren zur Sterilisation von wässrigen Polysaccharidlösungen und sterile wässrige Polysaccharidlösungen
AR108280A1 (es) 2016-05-05 2018-08-08 Acraf Composición oftálmica que comprende una combinación sinérgica de glucógeno y ácido hialurónico o sal del mismo
US20190240251A1 (en) * 2016-10-14 2019-08-08 i.com medical GmbH Method for establishing, restoring, and preserving homeostasis of the ocular surface
WO2019073362A1 (en) * 2017-10-12 2019-04-18 Solyplus Berlin Gmbh METHODS OF MANUFACTURING HOMOGENEOUSLY CONCENTRATED AND HOMOGENOUS MASS POLYMERS AND THEIR APPLICATIONS
CN111196917B (zh) * 2018-11-20 2022-10-14 臧唯 内窥镜用视野清晰剂
KR20220049525A (ko) * 2019-08-21 2022-04-21 가부시키가이샤 시세이도 화장료
IT201900019724A1 (it) 2019-10-24 2021-04-24 Bmg Pharma S P A “procedimento in solvente organico per la purificazione dell’acido ialuronico sale sodico”
IT202000008299A1 (it) * 2020-04-17 2021-10-17 Glycores 2000 Srl Composizione liquida oftalmica comprendente acido ialuronico lineare a basso peso molecolare
KR102549875B1 (ko) * 2020-09-22 2023-07-03 주식회사 필코리아 필러 정제용 장치
CN112255345A (zh) * 2020-10-20 2021-01-22 山东华熙海御生物医药有限公司 一种测定高分子量透明质酸分子量的方法
KR102762718B1 (ko) * 2022-02-23 2025-02-06 주식회사 스카이테라퓨틱스 고분자 히알루론산의 구조체, 이의 제조방법 및 이를 포함하는 화장료 조성물

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4141973A (en) 1975-10-17 1979-02-27 Biotrics, Inc. Ultrapure hyaluronic acid and the use thereof
DE2837115A1 (de) 1978-08-25 1980-03-06 Bayer Ag Neues verfahren zur herstellung von sterilen feststoffen
US5093487A (en) 1986-01-06 1992-03-03 Mobay Corporation Low viscosity high molecular weight filter sterilizable hyaluronic acid
RU2067841C1 (ru) * 1994-01-28 1996-10-20 Научно-производственная фирма "Нарт" Способ получения ароматизатора
IT1273011B (it) 1994-07-25 1997-07-01 Trhecnopharma S A Preparato oftalmico per l'uso come lacrima artificiale
US5621093A (en) 1995-06-06 1997-04-15 Anika Research, Inc. Steam-sterilizing solid hyaluronic acid
EP0888776A4 (en) * 1996-03-15 2005-01-26 Takara Bio Inc PRODUCT OBTAINED BY THERMAL TREATMENT OF URONIC ACID, AND FOOD, BEVERAGES OR MEDICAMENTS CONTAINING THE SAME
KR19980080116A (ko) 1997-03-27 1998-11-25 히라따 다다시 히알루론산 나트륨의 정제법
US6149864A (en) 1998-06-25 2000-11-21 Massachusetts Institute Of Technology Supercritical fluid sterilization method
CH692919A5 (fr) 1999-01-28 2002-12-13 Trb Chemedica S A Procédé de purification de l'acide hyaluronique à poids moléculaire élevé.
KR100354606B1 (ko) 2000-02-01 2002-09-30 주식회사 중외제약 다목적 콘택트 렌즈 관리 용액 조성물
FR2811996B1 (fr) * 2000-07-19 2003-08-08 Corneal Ind Reticulation de polysaccharide(s), preparation d'hydrogel(s) ; polysaccharide(s) et hydrogel(s) obtenus,leurs utilisations
EP1401508A1 (en) 2001-06-29 2004-03-31 Biovitrum Ab Process for bulk autoclaving
JP4436131B2 (ja) * 2001-11-21 2010-03-24 イオルテク ヒアルロン酸を安定化させる組成物
MXPA05000533A (es) 2002-08-07 2005-04-19 Medidom Lab Proceso para preparar una formulacion esteril de acido hialuronico de alto peso molecular.
US6930077B2 (en) 2003-09-10 2005-08-16 Advanced Medical Optics, Inc. Compositions and methods using sub-PPM combinations of polyquaternium-1 and high molecular weight PHMB
US7956180B2 (en) * 2004-05-27 2011-06-07 Novozymes A/S Dried and agglomerated hyaluronic acid product
AU2005262070B2 (en) 2004-07-09 2011-01-27 Ferrosan Medical Devices A/S Haemostatic composition comprising hyaluronic acid
DE102005030011A1 (de) 2005-06-17 2006-12-21 Aesculap Ag & Co. Kg Verfahren zur Herstellung von sterilen Polysaccharidlösungen
US20090036554A1 (en) * 2007-08-01 2009-02-05 Burke Susan E Ophthalmic compositions comprising a terpene compound
CA2705850C (en) * 2007-11-13 2016-07-19 Bio-Technology General (Israel) Ltd. Dilute filtration sterilization process for viscoelastic biopolymers
WO2010030725A1 (en) * 2008-09-15 2010-03-18 Bausch & Lomb Incorporated Compositions comprising polymers having amino sugar units and methods of making and using same

Also Published As

Publication number Publication date
EP2865395A1 (en) 2015-04-29
JP2013518926A (ja) 2013-05-23
US20120295869A1 (en) 2012-11-22
WO2011100114A1 (en) 2011-08-18
US8283463B2 (en) 2012-10-09
US8530641B2 (en) 2013-09-10
EP2400993B1 (en) 2014-12-31
PL2400993T3 (pl) 2015-06-30
BR112012019008B1 (pt) 2018-11-13
TWI405595B (zh) 2013-08-21
EP2400993A1 (en) 2012-01-04
TW201200171A (en) 2012-01-01
BR112012019008A2 (pt) 2015-09-15
JP5789271B2 (ja) 2015-10-07
BR112012019008B8 (pt) 2018-11-27
US20110195925A1 (en) 2011-08-11

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