ES2531955T3 - Soluciones estériles de ácido hialurónico - Google Patents

Soluciones estériles de ácido hialurónico Download PDF

Info

Publication number
ES2531955T3
ES2531955T3 ES11702563.5T ES11702563T ES2531955T3 ES 2531955 T3 ES2531955 T3 ES 2531955T3 ES 11702563 T ES11702563 T ES 11702563T ES 2531955 T3 ES2531955 T3 ES 2531955T3
Authority
ES
Spain
Prior art keywords
hyaluronic acid
solution
weight
saline
filtration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES11702563.5T
Other languages
English (en)
Spanish (es)
Inventor
Xiaojun Michael Liu
David Joseph Heiler
Thomas Menzel
Abbie BRONGO
Susan E. Burke
Karl Cummins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bausch and Lomb Inc
Original Assignee
Bausch and Lomb Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bausch and Lomb Inc filed Critical Bausch and Lomb Inc
Application granted granted Critical
Publication of ES2531955T3 publication Critical patent/ES2531955T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/022—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
ES11702563.5T 2010-02-09 2011-01-27 Soluciones estériles de ácido hialurónico Active ES2531955T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US702540 2010-02-09
US12/702,540 US8283463B2 (en) 2010-02-09 2010-02-09 Sterile hyaluronic acid solutions
PCT/US2011/022656 WO2011100114A1 (en) 2010-02-09 2011-01-27 Sterile hyaluronic acid solutions

Publications (1)

Publication Number Publication Date
ES2531955T3 true ES2531955T3 (es) 2015-03-23

Family

ID=43754892

Family Applications (1)

Application Number Title Priority Date Filing Date
ES11702563.5T Active ES2531955T3 (es) 2010-02-09 2011-01-27 Soluciones estériles de ácido hialurónico

Country Status (8)

Country Link
US (2) US8283463B2 (enExample)
EP (2) EP2400993B1 (enExample)
JP (1) JP5789271B2 (enExample)
BR (1) BR112012019008B8 (enExample)
ES (1) ES2531955T3 (enExample)
PL (1) PL2400993T3 (enExample)
TW (1) TWI405595B (enExample)
WO (1) WO2011100114A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10189773B2 (en) 2010-05-07 2019-01-29 Medicus Biosciences, Llc In-vivo gelling pharmaceutical pre-formulation
EP2606828B1 (en) * 2011-12-20 2018-04-11 Angioclinic AG Hyaluronic acid and its use for treating venous insufficiency and varicose veins
US10111985B2 (en) * 2011-08-10 2018-10-30 Medicus Biosciences, Llc Biocompatible hydrogel polymer formulations for the controlled delivery of biomolecules
US11083821B2 (en) * 2011-08-10 2021-08-10 C.P. Medical Corporation Biocompatible hydrogel polymer formulations for the controlled delivery of biomolecules
EP2846847B1 (en) 2012-05-11 2020-03-25 C.P. Medical Corporation Biocompatible hydrogel treatments for retinal detachment
FR3019465B1 (fr) 2014-04-02 2017-06-23 Horus Pharma Composition hyperosmolaire d'acide hyaluronique et son utilisation pour le traitement de l'oedeme corneen
WO2015158815A2 (en) 2014-04-17 2015-10-22 Merz Pharma Gmbh & Co. Kgaa Composition for improving the appearance of ageing skin
US10245324B2 (en) * 2014-10-31 2019-04-02 Johnson & Johnson Consumer Inc. Ophthalmic composition
US20170014339A1 (en) * 2015-07-17 2017-01-19 i.com medical GmbH Tear Substitute, Fluid for Being Used as a Tear Substitute, and Method for Producing a Tear Substitute
DE102015226456A1 (de) 2015-12-22 2017-06-22 Heraeus Medical Gmbh Verfahren zur Sterilisation von wässrigen Polysaccharidlösungen und sterile wässrige Polysaccharidlösungen
AR108280A1 (es) 2016-05-05 2018-08-08 Acraf Composición oftálmica que comprende una combinación sinérgica de glucógeno y ácido hialurónico o sal del mismo
KR20190068575A (ko) * 2016-10-14 2019-06-18 이콤 메디칼 게엠베하 안구 표면 항상성의 확립, 회복 및 보존 방법
ES2975184T3 (es) * 2017-10-12 2024-07-03 Solyplus Gmbh Métodos de fabricación de polímeros masivos concentrados y homogéneamente humectados y aplicaciones de los mismos
CN111196917B (zh) * 2018-11-20 2022-10-14 臧唯 内窥镜用视野清晰剂
WO2021033725A1 (ja) * 2019-08-21 2021-02-25 株式会社 資生堂 化粧料
IT201900019724A1 (it) 2019-10-24 2021-04-24 Bmg Pharma S P A “procedimento in solvente organico per la purificazione dell’acido ialuronico sale sodico”
IT202000008299A1 (it) * 2020-04-17 2021-10-17 Glycores 2000 Srl Composizione liquida oftalmica comprendente acido ialuronico lineare a basso peso molecolare
KR102549875B1 (ko) * 2020-09-22 2023-07-03 주식회사 필코리아 필러 정제용 장치
CN112255345A (zh) * 2020-10-20 2021-01-22 山东华熙海御生物医药有限公司 一种测定高分子量透明质酸分子量的方法
KR102762718B1 (ko) * 2022-02-23 2025-02-06 주식회사 스카이테라퓨틱스 고분자 히알루론산의 구조체, 이의 제조방법 및 이를 포함하는 화장료 조성물

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4141973A (en) * 1975-10-17 1979-02-27 Biotrics, Inc. Ultrapure hyaluronic acid and the use thereof
DE2837115A1 (de) 1978-08-25 1980-03-06 Bayer Ag Neues verfahren zur herstellung von sterilen feststoffen
US5093487A (en) * 1986-01-06 1992-03-03 Mobay Corporation Low viscosity high molecular weight filter sterilizable hyaluronic acid
RU2067841C1 (ru) * 1994-01-28 1996-10-20 Научно-производственная фирма "Нарт" Способ получения ароматизатора
IT1273011B (it) 1994-07-25 1997-07-01 Trhecnopharma S A Preparato oftalmico per l'uso come lacrima artificiale
US5621093A (en) 1995-06-06 1997-04-15 Anika Research, Inc. Steam-sterilizing solid hyaluronic acid
KR19990087665A (ko) * 1996-03-15 1999-12-27 오미야 히사시 우론산의 가열-처리 산물, 이를 함유하는 식품, 음료 또는 약제
KR19980080116A (ko) 1997-03-27 1998-11-25 히라따 다다시 히알루론산 나트륨의 정제법
US6149864A (en) 1998-06-25 2000-11-21 Massachusetts Institute Of Technology Supercritical fluid sterilization method
CH692919A5 (fr) 1999-01-28 2002-12-13 Trb Chemedica S A Procédé de purification de l'acide hyaluronique à poids moléculaire élevé.
KR100354606B1 (ko) 2000-02-01 2002-09-30 주식회사 중외제약 다목적 콘택트 렌즈 관리 용액 조성물
FR2811996B1 (fr) * 2000-07-19 2003-08-08 Corneal Ind Reticulation de polysaccharide(s), preparation d'hydrogel(s) ; polysaccharide(s) et hydrogel(s) obtenus,leurs utilisations
CA2447383A1 (en) 2001-06-29 2003-01-09 Biovitrum Ab Process for bulk autoclaving
AU2002360939A1 (en) * 2001-11-21 2003-06-10 Novartis Ag Composition for stabilizing hyaluronic acid
KR101169473B1 (ko) * 2002-08-07 2012-07-30 라보라뚜와르 메디동 에스.에이. 고분자 히알루론산 조성물 제조방법
US6930077B2 (en) * 2003-09-10 2005-08-16 Advanced Medical Optics, Inc. Compositions and methods using sub-PPM combinations of polyquaternium-1 and high molecular weight PHMB
US7956180B2 (en) * 2004-05-27 2011-06-07 Novozymes A/S Dried and agglomerated hyaluronic acid product
JP4959557B2 (ja) 2004-07-09 2012-06-27 フェロサン メディカル デバイシーズ エイ／エス ヒアルロン酸含有止血合成剤
DE102005030011A1 (de) 2005-06-17 2006-12-21 Aesculap Ag & Co. Kg Verfahren zur Herstellung von sterilen Polysaccharidlösungen
US20090036554A1 (en) * 2007-08-01 2009-02-05 Burke Susan E Ophthalmic compositions comprising a terpene compound
EP2209814B1 (en) * 2007-11-13 2017-01-25 Bio-Technology General (Israel) Ltd. Dilute filtration sterilization process for viscoelastic biopolymers
EP2346513A1 (en) * 2008-09-15 2011-07-27 Bausch & Lomb Incorporated Compositions comprising polymers having amino sugar units and methods of making and using same

Also Published As

Publication number Publication date
BR112012019008B8 (pt) 2018-11-27
PL2400993T3 (pl) 2015-06-30
TW201200171A (en) 2012-01-01
EP2400993B1 (en) 2014-12-31
US8530641B2 (en) 2013-09-10
US20120295869A1 (en) 2012-11-22
BR112012019008B1 (pt) 2018-11-13
EP2865395A1 (en) 2015-04-29
TWI405595B (zh) 2013-08-21
WO2011100114A1 (en) 2011-08-18
JP5789271B2 (ja) 2015-10-07
BR112012019008A2 (pt) 2015-09-15
US8283463B2 (en) 2012-10-09
EP2400993A1 (en) 2012-01-04
JP2013518926A (ja) 2013-05-23
US20110195925A1 (en) 2011-08-11

Similar Documents

Publication Publication Date Title
ES2531955T3 (es) Soluciones estériles de ácido hialurónico
Oprea et al. Recent advances in applications of cellulose derivatives-based composite membranes with hydroxyapatite
Valachová et al. Versatile use of chitosan and hyaluronan in medicine
US4440662A (en) Cleaning composition for contact lenses
JP6240665B2 (ja) ポリマー系透析物
ES2622498T3 (es) Composiciones y usos de materiales con actividad antimicrobiana elevada y toxicidad baja
Silva et al. Marine-derived polymers in ionic liquids: architectures development and biomedical applications
Zhu et al. Antibacterial hydrogels for wound dressing applications: Current status, progress, challenges, and trends
Kropp et al. Biocompatibility of poly (ester amide)(PEA) microfibrils in ocular tissues
Mehwish et al. Mussel-inspired surface functionalization of porous albumin cryogels supporting synergistic antibacterial/antioxidant activity and bone-like apatite formation
Parcheta et al. Preparation and functionalization of polymers with antibacterial properties—Review of the recent developments
Blažic et al. Cellulose-g-poly (2-(dimethylamino) ethylmethacrylate) hydrogels: synthesis, characterization, antibacterial testing and polymer electrolyte application
Cojocaru et al. Electrospun/3D-printed bicomponent scaffold co-loaded with a prodrug and a drug with antibacterial and immunomodulatory properties
Berton et al. Ionic liquids as tools to incorporate pharmaceutical ingredients into biopolymer-based drug delivery systems
Long et al. Normal-pressure-prepared chitosan carbonate liquid dressing: Spontaneous transformation into a pure chitosan water-resistant film and enhanced wound repair
CN106310221B (zh) 一种含有卡非佐米的药物组合物及其制备方法
KR20100092843A (ko) 콘택트렌즈 보존제
KR101169473B1 (ko) 고분자 히알루론산 조성물 제조방법
CN101977938B (zh) 海藻酸盐的超纯化方法
CN115058025B (zh) 无助溶物的含氨基难溶高分子溶液、制备方法及其应用
RU2280041C1 (ru) Способ получения водорастворимых солевых комплексов гиалуроновой кислоты (варианты)
Gulyakin et al. Use of Membrane Filters in Production Technology for Sterile Drugs
Wang et al. Biofunctional carboxymethyl chitosan hydrogel incorporating hyaluronic acid and RGD peptides for accelerated wound repair
KR20150068647A (ko) 폴리데옥시리보뉴클레오티드 미세입자를 함유하는 점안제 조성물 및 이의 제조방법
CN119424323B (zh) 一种甘露醇注射液及其生产方法