ES2531955T3 - Soluciones estériles de ácido hialurónico - Google Patents

Soluciones estériles de ácido hialurónico Download PDF

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Publication number
ES2531955T3
ES2531955T3 ES11702563.5T ES11702563T ES2531955T3 ES 2531955 T3 ES2531955 T3 ES 2531955T3 ES 11702563 T ES11702563 T ES 11702563T ES 2531955 T3 ES2531955 T3 ES 2531955T3
Authority
ES
Spain
Prior art keywords
hyaluronic acid
solution
weight
saline
filtration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES11702563.5T
Other languages
English (en)
Spanish (es)
Inventor
Xiaojun Michael Liu
David Joseph Heiler
Thomas Menzel
Abbie BRONGO
Susan E. Burke
Karl Cummins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bausch and Lomb Inc
Original Assignee
Bausch and Lomb Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bausch and Lomb Inc filed Critical Bausch and Lomb Inc
Application granted granted Critical
Publication of ES2531955T3 publication Critical patent/ES2531955T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/022—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
ES11702563.5T 2010-02-09 2011-01-27 Soluciones estériles de ácido hialurónico Active ES2531955T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US702540 2010-02-09
US12/702,540 US8283463B2 (en) 2010-02-09 2010-02-09 Sterile hyaluronic acid solutions
PCT/US2011/022656 WO2011100114A1 (en) 2010-02-09 2011-01-27 Sterile hyaluronic acid solutions

Publications (1)

Publication Number Publication Date
ES2531955T3 true ES2531955T3 (es) 2015-03-23

Family

ID=43754892

Family Applications (1)

Application Number Title Priority Date Filing Date
ES11702563.5T Active ES2531955T3 (es) 2010-02-09 2011-01-27 Soluciones estériles de ácido hialurónico

Country Status (8)

Country Link
US (2) US8283463B2 (enExample)
EP (2) EP2865395A1 (enExample)
JP (1) JP5789271B2 (enExample)
BR (1) BR112012019008B8 (enExample)
ES (1) ES2531955T3 (enExample)
PL (1) PL2400993T3 (enExample)
TW (1) TWI405595B (enExample)
WO (1) WO2011100114A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10227289B2 (en) 2010-05-07 2019-03-12 Medicus Biosciences, Llc Methods for treating diseases of the lung
US10111985B2 (en) * 2011-08-10 2018-10-30 Medicus Biosciences, Llc Biocompatible hydrogel polymer formulations for the controlled delivery of biomolecules
US11083821B2 (en) * 2011-08-10 2021-08-10 C.P. Medical Corporation Biocompatible hydrogel polymer formulations for the controlled delivery of biomolecules
ES2686114T3 (es) * 2011-12-20 2018-10-16 Angioclinic Ag El ácido hialurónico y su uso para el tratamiento de la insuficiencia venosa y las venas varicosas
JP6206987B2 (ja) 2012-05-11 2017-10-04 メディカス バイオサイエンシーズ，エルエルシー 網膜剥離の処置のための生体適合性ヒドロゲル製剤
FR3019465B1 (fr) 2014-04-02 2017-06-23 Horus Pharma Composition hyperosmolaire d'acide hyaluronique et son utilisation pour le traitement de l'oedeme corneen
ES2837062T3 (es) 2014-04-17 2021-06-29 Merz Pharma Gmbh & Co Kgaa Composición para mejorar el aspecto de la piel envejecida
US10245324B2 (en) 2014-10-31 2019-04-02 Johnson & Johnson Consumer Inc. Ophthalmic composition
US20170014339A1 (en) * 2015-07-17 2017-01-19 i.com medical GmbH Tear Substitute, Fluid for Being Used as a Tear Substitute, and Method for Producing a Tear Substitute
DE102015226456A1 (de) 2015-12-22 2017-06-22 Heraeus Medical Gmbh Verfahren zur Sterilisation von wässrigen Polysaccharidlösungen und sterile wässrige Polysaccharidlösungen
AR108280A1 (es) 2016-05-05 2018-08-08 Acraf Composición oftálmica que comprende una combinación sinérgica de glucógeno y ácido hialurónico o sal del mismo
ES2909998T3 (es) * 2016-10-14 2022-05-11 I Com Medical Gmbh Método para establecer, restablecer y preservar la homeostasis de la superficie ocular
ES2975184T3 (es) * 2017-10-12 2024-07-03 Solyplus Gmbh Métodos de fabricación de polímeros masivos concentrados y homogéneamente humectados y aplicaciones de los mismos
CN111196917B (zh) * 2018-11-20 2022-10-14 臧唯 内窥镜用视野清晰剂
US20220273545A1 (en) * 2019-08-21 2022-09-01 Shiseido Company, Ltd. Cosmetic
IT201900019724A1 (it) 2019-10-24 2021-04-24 Bmg Pharma S P A “procedimento in solvente organico per la purificazione dell’acido ialuronico sale sodico”
IT202000008299A1 (it) * 2020-04-17 2021-10-17 Glycores 2000 Srl Composizione liquida oftalmica comprendente acido ialuronico lineare a basso peso molecolare
KR102549875B1 (ko) * 2020-09-22 2023-07-03 주식회사 필코리아 필러 정제용 장치
CN112255345A (zh) * 2020-10-20 2021-01-22 山东华熙海御生物医药有限公司 一种测定高分子量透明质酸分子量的方法
KR102762718B1 (ko) * 2022-02-23 2025-02-06 주식회사 스카이테라퓨틱스 고분자 히알루론산의 구조체, 이의 제조방법 및 이를 포함하는 화장료 조성물

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4141973A (en) 1975-10-17 1979-02-27 Biotrics, Inc. Ultrapure hyaluronic acid and the use thereof
DE2837115A1 (de) 1978-08-25 1980-03-06 Bayer Ag Neues verfahren zur herstellung von sterilen feststoffen
US5093487A (en) 1986-01-06 1992-03-03 Mobay Corporation Low viscosity high molecular weight filter sterilizable hyaluronic acid
RU2067841C1 (ru) * 1994-01-28 1996-10-20 Научно-производственная фирма "Нарт" Способ получения ароматизатора
IT1273011B (it) 1994-07-25 1997-07-01 Trhecnopharma S A Preparato oftalmico per l'uso come lacrima artificiale
US5621093A (en) 1995-06-06 1997-04-15 Anika Research, Inc. Steam-sterilizing solid hyaluronic acid
WO1997033593A1 (en) * 1996-03-15 1997-09-18 Takara Shuzo Co., Ltd. A product of heat treatment of uronic acid, food, drink or drug including the product
KR19980080116A (ko) 1997-03-27 1998-11-25 히라따 다다시 히알루론산 나트륨의 정제법
US6149864A (en) 1998-06-25 2000-11-21 Massachusetts Institute Of Technology Supercritical fluid sterilization method
CH692919A5 (fr) 1999-01-28 2002-12-13 Trb Chemedica S A Procédé de purification de l'acide hyaluronique à poids moléculaire élevé.
KR100354606B1 (ko) 2000-02-01 2002-09-30 주식회사 중외제약 다목적 콘택트 렌즈 관리 용액 조성물
FR2811996B1 (fr) * 2000-07-19 2003-08-08 Corneal Ind Reticulation de polysaccharide(s), preparation d'hydrogel(s) ; polysaccharide(s) et hydrogel(s) obtenus,leurs utilisations
CN1522161A (zh) 2001-06-29 2004-08-18 �Ȱ�ά����ķ�ɷݹ�˾ 批量高压灭菌方法
ATE547122T1 (de) * 2001-11-21 2012-03-15 Novartis Pharma Gmbh Zusammensetzung zur stabilisierung von hyaluronsäure
CN100366296C (zh) 2002-08-07 2008-02-06 梅迪多姆实验室股份有限公司 制备无菌高分子量透明质酸制剂的方法
US6930077B2 (en) 2003-09-10 2005-08-16 Advanced Medical Optics, Inc. Compositions and methods using sub-PPM combinations of polyquaternium-1 and high molecular weight PHMB
US7956180B2 (en) * 2004-05-27 2011-06-07 Novozymes A/S Dried and agglomerated hyaluronic acid product
RU2369408C2 (ru) 2004-07-09 2009-10-10 Ферросан А/С Гемостатическая композиция, включающая гиалуроновую кислоту
DE102005030011A1 (de) 2005-06-17 2006-12-21 Aesculap Ag & Co. Kg Verfahren zur Herstellung von sterilen Polysaccharidlösungen
US20090036554A1 (en) * 2007-08-01 2009-02-05 Burke Susan E Ophthalmic compositions comprising a terpene compound
ES2622834T3 (es) * 2007-11-13 2017-07-07 Bio-Technology General (Israel) Ltd. Procedimiento de esterilización por filtración en estado diluido para biopolímeros viscoelásticos
EP2346513A1 (en) * 2008-09-15 2011-07-27 Bausch & Lomb Incorporated Compositions comprising polymers having amino sugar units and methods of making and using same

Also Published As

Publication number Publication date
EP2400993B1 (en) 2014-12-31
BR112012019008A2 (pt) 2015-09-15
EP2865395A1 (en) 2015-04-29
BR112012019008B1 (pt) 2018-11-13
TW201200171A (en) 2012-01-01
PL2400993T3 (pl) 2015-06-30
US8283463B2 (en) 2012-10-09
TWI405595B (zh) 2013-08-21
US20110195925A1 (en) 2011-08-11
EP2400993A1 (en) 2012-01-04
US8530641B2 (en) 2013-09-10
JP2013518926A (ja) 2013-05-23
BR112012019008B8 (pt) 2018-11-27
WO2011100114A1 (en) 2011-08-18
JP5789271B2 (ja) 2015-10-07
US20120295869A1 (en) 2012-11-22

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