ES2489475T3 - Inhibidores MET para potenciar la eficacia de la radioterapia - Google Patents
Inhibidores MET para potenciar la eficacia de la radioterapia Download PDFInfo
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- ES2489475T3 ES2489475T3 ES11158861.2T ES11158861T ES2489475T3 ES 2489475 T3 ES2489475 T3 ES 2489475T3 ES 11158861 T ES11158861 T ES 11158861T ES 2489475 T3 ES2489475 T3 ES 2489475T3
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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- A—HUMAN NECESSITIES
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| US9168300B2 (en) | 2013-03-14 | 2015-10-27 | Oncomed Pharmaceuticals, Inc. | MET-binding agents and uses thereof |
| TWI782930B (zh) | 2016-11-16 | 2022-11-11 | 美商再生元醫藥公司 | 抗ｍｅｔ抗體，結合ｍｅｔ之雙特異性抗原結合分子及其使用方法 |
| IT201800009282A1 (it) * | 2018-10-09 | 2020-04-09 | Metis Prec Medicine Sb Srl | Nuovo agente terapeutico per il trattamento di un tumore e/o metastasi |
| CN110320365B (zh) * | 2019-07-06 | 2022-07-22 | 湖南莱拓福生物科技有限公司 | NF-κB RelA/p65蛋白位点特异性磷酸化诊断试剂盒 |
| CN121015920A (zh) | 2019-09-16 | 2025-11-28 | 瑞泽恩制药公司 | 用于免疫pet成像的放射性标记的met结合蛋白 |
| EP4687905A1 (en) | 2023-03-30 | 2026-02-11 | Revolution Medicines, Inc. | Compositions for inducing ras gtp hydrolysis and uses thereof |
| WO2024229406A1 (en) | 2023-05-04 | 2024-11-07 | Revolution Medicines, Inc. | Combination therapy for a ras related disease or disorder |
| WO2025034702A1 (en) | 2023-08-07 | 2025-02-13 | Revolution Medicines, Inc. | Rmc-6291 for use in the treatment of ras protein-related disease or disorder |
| US20250154171A1 (en) | 2023-10-12 | 2025-05-15 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025171296A1 (en) | 2024-02-09 | 2025-08-14 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025240847A1 (en) | 2024-05-17 | 2025-11-20 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025255438A1 (en) | 2024-06-07 | 2025-12-11 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| WO2025265060A1 (en) | 2024-06-21 | 2025-12-26 | Revolution Medicines, Inc. | Therapeutic compositions and methods for managing treatment-related effects |
| WO2026006747A1 (en) | 2024-06-28 | 2026-01-02 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026015825A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Use of ras inhibitor for treating pancreatic cancer |
| WO2026015801A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015790A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015796A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
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| TWI310684B (en) * | 2000-03-27 | 2009-06-11 | Bristol Myers Squibb Co | Synergistic pharmaceutical kits for treating cancer |
| EP1592713A2 (en) * | 2003-02-13 | 2005-11-09 | Pharmacia Corporation | Antibodies to c-met for the treatment of cancers |
| BRPI0412885A (pt) * | 2003-07-18 | 2006-10-03 | Amgen Inc | polipeptìdios, agentes de ligação especìficos, moléculas de ácido nucleico e linhas de células isoladas, células hospedeiras, composições e anticorpo ou domìnio de ligação de antìgeno e métodos de tratamento de cáncer e de tumor sólido num paciente, de detecção do nìvel do fator de crescimento hepatócito (hgf) numa amostra, de obtenção de anticorpo e de inibição da ligação de hgf a met e de diminuição ou prevenção da ligação de qualquer um dos agentes de ligação especìficos ao fator de crescimento hepatócito (hgf) |
| HN2004000285A (es) * | 2003-08-04 | 2006-04-27 | Pfizer Prod Inc | ANTICUERPOS DIRIGIDOS A c-MET |
| PT1981981E (pt) * | 2006-02-06 | 2011-10-04 | Metheresis Translational Res Sa | Anticorpos monoclonais anti-met, fragmentos e vectores destes, para o tratamento de tumores e produtos correspondentes |
| EP2019116A1 (en) * | 2007-07-26 | 2009-01-28 | Helmholtz-Zentrum für Infektionsforschung GmbH | Inhibitor of the met-receptor and its use |
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2011
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Also Published As
| Publication number | Publication date |
|---|---|
| MX2012003084A (es) | 2012-09-17 |
| EA028590B1 (ru) | 2017-12-29 |
| SMT201400106B (it) | 2014-11-10 |
| HRP20140729T1 (hr) | 2014-08-29 |
| CN102688491A (zh) | 2012-09-26 |
| JP5671487B2 (ja) | 2015-02-18 |
| AU2012201303B2 (en) | 2013-11-07 |
| KR20120106582A (ko) | 2012-09-26 |
| BR102012006063B1 (pt) | 2023-03-07 |
| BR102012006063A2 (pt) | 2021-11-16 |
| EP2500036A1 (en) | 2012-09-19 |
| EA201200329A3 (ru) | 2013-01-30 |
| SI2500036T1 (sl) | 2014-09-30 |
| SG184637A1 (en) | 2012-10-30 |
| BR102012006063A8 (pt) | 2022-11-08 |
| IL218293A (en) | 2016-06-30 |
| AU2012201303A1 (en) | 2012-10-04 |
| KR101540838B1 (ko) | 2015-08-06 |
| CA2769991A1 (en) | 2012-09-18 |
| HK1174539A1 (en) | 2013-06-14 |
| EA201200329A2 (ru) | 2012-09-28 |
| PL2500036T3 (pl) | 2014-10-31 |
| US20120237524A1 (en) | 2012-09-20 |
| CA2769991C (en) | 2018-05-15 |
| CY1115374T1 (el) | 2017-01-04 |
| RS53468B (sr) | 2014-12-31 |
| IL218293A0 (en) | 2012-07-31 |
| EP2500036B1 (en) | 2014-05-07 |
| PT2500036E (pt) | 2014-08-25 |
| ZA201201992B (en) | 2015-05-27 |
| JP2012196206A (ja) | 2012-10-18 |
| DK2500036T3 (da) | 2014-08-04 |
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