ES2458168T3 - Moduladores de TGR5 y método de uso de los mismos - Google Patents
Moduladores de TGR5 y método de uso de los mismos Download PDFInfo
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- ES2458168T3 ES2458168T3 ES09760057.1T ES09760057T ES2458168T3 ES 2458168 T3 ES2458168 T3 ES 2458168T3 ES 09760057 T ES09760057 T ES 09760057T ES 2458168 T3 ES2458168 T3 ES 2458168T3
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- hydrogen
- tgr5
- ih3e
- hydroxyl
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Gastroenterology & Hepatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
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- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08169462 | 2008-11-19 | ||
| EP08169462 | 2008-11-19 | ||
| PCT/US2009/065188 WO2010059853A1 (en) | 2008-11-19 | 2009-11-19 | Tgr5 modulators and method of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2458168T3 true ES2458168T3 (es) | 2014-04-30 |
Family
ID=41668454
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| ES09760057.1T Active ES2458168T3 (es) | 2008-11-19 | 2009-11-19 | Moduladores de TGR5 y método de uso de los mismos |
| ES13192394T Active ES2663948T3 (es) | 2008-11-19 | 2009-11-19 | Moduladores de TGR5 y método de uso de los mismos |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
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| ES13192394T Active ES2663948T3 (es) | 2008-11-19 | 2009-11-19 | Moduladores de TGR5 y método de uso de los mismos |
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| EP (2) | EP2698375B1 (enExample) |
| JP (5) | JP5535233B2 (enExample) |
| KR (2) | KR101667436B1 (enExample) |
| CN (2) | CN104370990A (enExample) |
| AU (1) | AU2009316566B9 (enExample) |
| BR (1) | BRPI0921983B8 (enExample) |
| CA (1) | CA2744189C (enExample) |
| DK (2) | DK2376519T3 (enExample) |
| EA (2) | EA020140B1 (enExample) |
| ES (2) | ES2458168T3 (enExample) |
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| HU (1) | HUE039171T2 (enExample) |
| IL (3) | IL212969A (enExample) |
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| MX (1) | MX2011005295A (enExample) |
| NO (1) | NO2698375T3 (enExample) |
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| SI (1) | SI2698375T1 (enExample) |
| WO (1) | WO2010059853A1 (enExample) |
| ZA (1) | ZA201104077B (enExample) |
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| CA2928178C (en) | 2007-01-19 | 2019-09-10 | Intercept Pharmaceuticals, Inc. | Tgr5 modulators and methods of use thereof |
| US8796249B2 (en) | 2008-07-30 | 2014-08-05 | Intercept Pharmaceuticals, Inc. | TGR5 modulators and methods of use thereof |
| HUE039171T2 (hu) * | 2008-11-19 | 2018-12-28 | Intercept Pharmaceuticals Inc | TGR5 modulátorok és azok alkalmazási eljárása |
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| US8318663B2 (en) | 2008-11-26 | 2012-11-27 | Satiogen Pharmaceuticals, Inc. | Methods of treating diabetes and/or obesity using an enteroendocrine peptide secretion enhancing agent |
| EP4137137A1 (en) | 2010-05-26 | 2023-02-22 | Satiogen Pharmaceuticals, Inc. | Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions |
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| EA038594B1 (ru) | 2011-10-28 | 2021-09-21 | Шайр Хьюман Дженетик Терапис, Инк. | Ингибиторы рециркуляции желчных кислот для лечения гиперхолемии и холестатического заболевания печени |
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| TW201700447A (zh) * | 2015-06-19 | 2017-01-01 | 英特賽普醫藥品公司 | Tgr5調控劑及其用法 |
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-
2009
- 2009-11-19 HU HUE13192394A patent/HUE039171T2/hu unknown
- 2009-11-19 CN CN201410532890.0A patent/CN104370990A/zh active Pending
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- 2009-11-19 PL PL09760057T patent/PL2376519T3/pl unknown
- 2009-11-19 PT PT131923948T patent/PT2698375T/pt unknown
- 2009-11-19 LT LTEP13192394.8T patent/LT2698375T/lt unknown
- 2009-11-19 US US12/622,123 patent/US8114862B2/en active Active
- 2009-11-19 WO PCT/US2009/065188 patent/WO2010059853A1/en not_active Ceased
- 2009-11-19 ES ES09760057.1T patent/ES2458168T3/es active Active
- 2009-11-19 KR KR1020117014037A patent/KR101667436B1/ko not_active Expired - Fee Related
- 2009-11-19 EP EP13192394.8A patent/EP2698375B1/en active Active
- 2009-11-19 EP EP09760057.1A patent/EP2376519B1/en active Active
- 2009-11-19 PL PL13192394T patent/PL2698375T3/pl unknown
- 2009-11-19 CN CN200980154713.0A patent/CN102325784B/zh active Active
- 2009-11-19 EA EA201170714A patent/EA020140B1/ru unknown
- 2009-11-19 SG SG10201400162QA patent/SG10201400162QA/en unknown
- 2009-11-19 DK DK13192394.8T patent/DK2698375T3/en active
- 2009-11-19 KR KR1020167028159A patent/KR101789960B1/ko not_active Expired - Fee Related
- 2009-11-19 CA CA2744189A patent/CA2744189C/en active Active
- 2009-11-19 PT PT97600571T patent/PT2376519E/pt unknown
- 2009-11-19 SI SI200931820T patent/SI2698375T1/sl unknown
- 2009-11-19 ES ES13192394T patent/ES2663948T3/es active Active
- 2009-11-19 MX MX2011005295A patent/MX2011005295A/es active IP Right Grant
- 2009-11-19 BR BRPI0921983A patent/BRPI0921983B8/pt not_active IP Right Cessation
- 2009-11-19 EA EA201400258A patent/EA030681B1/ru not_active IP Right Cessation
- 2009-11-19 NO NO13192394A patent/NO2698375T3/no unknown
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2011
- 2011-05-18 IL IL212969A patent/IL212969A/en active IP Right Grant
- 2011-06-01 ZA ZA2011/04077A patent/ZA201104077B/en unknown
- 2011-12-07 US US13/313,689 patent/US8445472B2/en not_active Expired - Fee Related
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2013
- 2013-04-26 US US13/871,492 patent/US9650409B2/en not_active Expired - Fee Related
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2014
- 2014-04-22 JP JP2014088019A patent/JP2014159456A/ja not_active Withdrawn
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2015
- 2015-06-10 HK HK15105499.8A patent/HK1205132A1/xx unknown
- 2015-08-14 JP JP2015160141A patent/JP2015232020A/ja active Pending
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2016
- 2016-03-29 IL IL244812A patent/IL244812B/en active IP Right Grant
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2017
- 2017-04-07 US US15/482,107 patent/US20180016295A1/en not_active Abandoned
- 2017-04-19 JP JP2017083045A patent/JP2017132803A/ja not_active Withdrawn
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2018
- 2018-03-27 JP JP2018059922A patent/JP2018100304A/ja not_active Withdrawn
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2019
- 2019-02-12 IL IL264796A patent/IL264796B/en active IP Right Grant
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2020
- 2020-11-09 US US17/092,612 patent/US20210269473A1/en not_active Abandoned
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