ES2439724T3 - Vectores de flavivirus quiméricos - Google Patents
Vectores de flavivirus quiméricos Download PDFInfo
- Publication number
- ES2439724T3 ES2439724T3 ES02756112.5T ES02756112T ES2439724T3 ES 2439724 T3 ES2439724 T3 ES 2439724T3 ES 02756112 T ES02756112 T ES 02756112T ES 2439724 T3 ES2439724 T3 ES 2439724T3
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- Prior art keywords
- virus
- flavivirus
- antigen
- protein
- vectors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
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- C12N2770/24011—Flaviviridae
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- C12N2770/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29526501P | 2001-06-01 | 2001-06-01 | |
| US295265P | 2001-06-01 | ||
| PCT/US2002/017374 WO2002102828A2 (en) | 2001-06-01 | 2002-05-31 | Chimeric flavivirus vectors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2439724T3 true ES2439724T3 (es) | 2014-01-24 |
Family
ID=23136958
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES02756112.5T Expired - Lifetime ES2439724T3 (es) | 2001-06-01 | 2002-05-31 | Vectores de flavivirus quiméricos |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7569383B2 (enExample) |
| EP (1) | EP1401859B1 (enExample) |
| JP (1) | JP2005501532A (enExample) |
| KR (1) | KR100921592B1 (enExample) |
| CN (1) | CN1551782A (enExample) |
| AU (1) | AU2002322026B2 (enExample) |
| BR (1) | BR0210907A (enExample) |
| CA (1) | CA2448971C (enExample) |
| ES (1) | ES2439724T3 (enExample) |
| PL (1) | PL371187A1 (enExample) |
| WO (1) | WO2002102828A2 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6962708B1 (en) * | 1997-02-28 | 2005-11-08 | Acambis, Inc. | Chimeric flavivirus vaccines |
| PL371187A1 (en) | 2001-06-01 | 2005-06-13 | Acambis, Inc. | Chimeric flavivirus vectors |
| US20050002968A1 (en) * | 2002-01-15 | 2005-01-06 | Monath Thomas P. | Flavivirus vaccines |
| JP2005519639A (ja) | 2002-01-15 | 2005-07-07 | アカンビス インコーポレーティッド | フラビウイルスワクチン |
| AU2003239932A1 (en) * | 2002-05-31 | 2003-12-19 | Acambis, Inc. | Tetravalent dengue vaccines |
| AU2003290985B2 (en) | 2002-11-15 | 2010-04-01 | Acambis Inc. | West nile virus vaccine |
| RU2009105099A (ru) * | 2006-07-14 | 2010-08-27 | Санофи Пастер Байолоджикс Ко. (Us) | Конструирование рекомбинантных вирусных вакцин путем прямой транспозон-опосредованной инсерции чужеродных иммунологических детерминант в белки векторного вируса |
| KR20090096414A (ko) * | 2006-09-29 | 2009-09-10 | 사노피 파스테르 바이오로직스 씨오 | 재조합 리노바이러스 벡터 |
| FR2906724B1 (fr) | 2006-10-04 | 2009-03-20 | Sanofi Pasteur Sa | Methode d'immunisation contre les 4 serotypes de la dengue. |
| CA2668834C (en) | 2006-11-07 | 2016-10-11 | Sanofi Pasteur Biologics Co. | Stabilization of vaccines by lyophilization |
| EP2117589A4 (en) * | 2007-01-31 | 2010-07-21 | Sanofi Pasteur Biologics Co | FLAVIVIRUS VACCINE VECTOR AGAINST INFLUENZA VIRUS |
| WO2009030872A1 (en) * | 2007-09-07 | 2009-03-12 | Mats Axel Atterdag Persson | Materials and methods for the treatment of hepatitis c |
| ES2615390T3 (es) | 2008-03-05 | 2017-06-06 | Sanofi Pasteur | Proceso para estabilizar una composición de vacuna que contiene adyuvante |
| JP5779352B2 (ja) | 2008-03-14 | 2015-09-16 | サノフィ パスツール バイオロジクス リミテッド ライアビリティ カンパニー | 複製欠損フラビウイルスワクチンおよびワクチンベクター |
| JP2011517408A (ja) * | 2008-03-27 | 2011-06-09 | サノフィ パスツール バイオロジクス カンパニー | 組換えライノウイルスベクター |
| EP2143440A1 (fr) | 2008-07-09 | 2010-01-13 | Sanofi Pasteur | Agent stabilisant et composition vaccinale comprenant un ou plusieurs flavivirus vivants atténués |
| EP2408477A4 (en) * | 2009-03-16 | 2013-03-27 | Sanofi Pasteur Biologics Llc | REPLICATION DEFECTS FLAVIVIRUS VACCINE VACCINATORS AGAINST RESPIRATORY SYNZYTIAL VIRUS |
| EP2353609A1 (en) | 2010-02-04 | 2011-08-10 | Sanofi Pasteur | Immunization compositions and methods |
| BR112014009887A2 (pt) * | 2011-10-25 | 2017-04-25 | Florida Gulf Coast Univ | vacinmas e métodos para desenvolvimento de vacina para indução de imunidade a todos os sorotipos de virus da dengue |
| MY168959A (en) | 2012-07-24 | 2019-01-28 | Sanofi Pasteur | Vaccine compositions for the prevention of dengue virus infection |
| CA2878599A1 (en) * | 2012-07-24 | 2014-01-30 | Jiansheng Yao | Vaccine compositions for prevention against dengue virus infection |
| BR112015012515B1 (pt) | 2012-11-30 | 2023-04-11 | Sanofi Pasteur | Uso de antígenos, construções de ácido nucleico ou vetores virais capazes de expressar uma partícula do tipo vírus (vlp) da dengue e de uma vacina contra sarampo, uma vacina contra caxumba e uma vacina contra rubéola |
| CN103352029A (zh) * | 2013-07-29 | 2013-10-16 | 中国人民解放军军事医学科学院微生物流行病研究所 | 一种乙脑/森林脑炎嵌合病毒及其应用 |
| US10428313B2 (en) | 2014-06-20 | 2019-10-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Chimeric West Nile/Dengue viruses and methods of use |
| TWI852899B (zh) | 2014-09-02 | 2024-08-21 | 法商賽諾菲巴斯德公司 | 疫苗組合物 |
| EP3031923A1 (en) * | 2014-12-11 | 2016-06-15 | Institut Pasteur | Lentiviral vector-based japanese encephalitis immunogenic composition |
| US10857222B2 (en) | 2015-07-03 | 2020-12-08 | Sanofi Pasteur | Concomitant dengue and yellow fever vaccination |
| WO2017109698A1 (en) | 2015-12-22 | 2017-06-29 | Glaxosmithkline Biologicals Sa | Immunogenic formulation |
| EP3184119A1 (en) | 2015-12-23 | 2017-06-28 | Themis Bioscience GmbH | Chromatography based purification strategies for measles scaffold based viruses |
| BR112019019813A2 (pt) | 2017-03-30 | 2020-04-22 | The University Of Queensland | moléculas quiméricas e usos das mesmas |
| EP3687561A4 (en) | 2017-09-01 | 2021-06-09 | The Australian National University | "immunoregulatory molecules and uses therefor" |
| AU2018346724B2 (en) | 2017-10-05 | 2025-01-09 | Sanofi Pasteur | Compositions for booster vaccination against dengue |
| US20220168412A1 (en) * | 2019-04-10 | 2022-06-02 | Katholieke Universiteit Leuven | Chimeric Zika-Japanese Encephalitis Virus |
| CN111798712B (zh) * | 2020-07-15 | 2021-10-29 | 周晓庆 | 噬菌体侵染细菌3d智能模拟方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6184024B1 (en) | 1988-07-14 | 2001-02-06 | The United States Of America As Represented By The Department Of Health And Human Services | Chimeric and/or growth-restricted flaviviruses |
| DE69230316T2 (de) | 1991-09-19 | 2000-07-13 | Us Health | Chimäre und/oder wachstumsgehemmte flaviviren |
| US6136561A (en) | 1995-05-24 | 2000-10-24 | Hawaii Biotechnology Group, Inc. | Methods of preparing carboxy-terminally truncated recombinant flavivirus envelope glycoproteins employing drosophila melanogaster expression systems |
| US6962708B1 (en) | 1997-02-28 | 2005-11-08 | Acambis, Inc. | Chimeric flavivirus vaccines |
| CA2282790C (en) | 1997-02-28 | 2011-04-19 | St. Louis University | Chimeric flavivirus vaccines |
| BRPI9701774B8 (pt) | 1997-04-11 | 2015-09-29 | Fundação Oswaldo Cruz Fiocruz | cdna mutante e infeccioso do vírus da febre amarela, constructo de dna, vírus recombinante de febre amarela e vacina para humanos contra infecções de febre amarela. |
| US6416763B1 (en) | 1998-08-28 | 2002-07-09 | Hawaii Biotechnology Group, Inc. | Recombinant nonstructural protein subunit vaccine against flaviviral infection |
| US6416783B1 (en) * | 1999-08-20 | 2002-07-09 | Wisconsin Alumni Research Foundation | Aspartic and malic acid inhibition of ss-glucuronidase |
| AU1813901A (en) | 1999-12-01 | 2001-06-12 | Oravax, Inc | Chimeric flavivirus vaccines |
| GB2372991B (en) * | 2001-03-09 | 2004-11-17 | Fiocruz Fundacao Oswaldo Cruz | Flavivirus expression vector |
| PL371187A1 (en) | 2001-06-01 | 2005-06-13 | Acambis, Inc. | Chimeric flavivirus vectors |
| US6682883B1 (en) | 2001-07-19 | 2004-01-27 | Acambis, Inc. | Diagnosis of flavivirus infection |
| DK1441761T3 (da) | 2001-10-19 | 2007-08-27 | Acambis Inc | Fremgangsmåder til forebyggelse og behandling af flavivirus-infektion hos dyr |
| US20050002968A1 (en) | 2002-01-15 | 2005-01-06 | Monath Thomas P. | Flavivirus vaccines |
| JP2005519639A (ja) | 2002-01-15 | 2005-07-07 | アカンビス インコーポレーティッド | フラビウイルスワクチン |
| AU2003239932A1 (en) | 2002-05-31 | 2003-12-19 | Acambis, Inc. | Tetravalent dengue vaccines |
| AU2003290985B2 (en) | 2002-11-15 | 2010-04-01 | Acambis Inc. | West nile virus vaccine |
| US7189403B2 (en) | 2003-06-30 | 2007-03-13 | Institut Pasteur | Attenuated flavivirus strains containing a mutated M-ectodomain and their applications |
| WO2005040390A1 (en) | 2003-07-21 | 2005-05-06 | Shanghai Tengen Biomedical Co., Ltd. | A recombinant vaccine using yellow fever virus as vector |
| WO2005049815A1 (en) | 2003-11-21 | 2005-06-02 | K.U.Leuven Research & Development | Flavivirus replication |
| WO2006044857A2 (en) | 2004-10-20 | 2006-04-27 | Acambis Inc. | Vaccines against japanese encephalitis virus and west nile virus |
| CN103031279B (zh) | 2005-04-24 | 2015-11-18 | 赛诺菲巴斯德生物制药有限责任公司 | 重组黄病毒疫苗 |
| BRPI0504945B8 (pt) | 2005-10-31 | 2022-08-02 | Fundacao Oswaldo Cruz | Método para a produção de flavivirus recombinante contendo sequências de nucleotídeos codificantes de uma proteína heteróloga, constructo de dna, flavivirus, e, composição vacinal para imunizar contra flavivirus e/ou outros patógenos. |
-
2002
- 2002-05-31 PL PL02371187A patent/PL371187A1/xx not_active Application Discontinuation
- 2002-05-31 WO PCT/US2002/017374 patent/WO2002102828A2/en not_active Ceased
- 2002-05-31 JP JP2003506300A patent/JP2005501532A/ja active Pending
- 2002-05-31 ES ES02756112.5T patent/ES2439724T3/es not_active Expired - Lifetime
- 2002-05-31 CN CNA028149602A patent/CN1551782A/zh active Pending
- 2002-05-31 BR BR0210907-7A patent/BR0210907A/pt not_active IP Right Cessation
- 2002-05-31 US US10/160,939 patent/US7569383B2/en not_active Expired - Fee Related
- 2002-05-31 KR KR1020037015734A patent/KR100921592B1/ko not_active Expired - Fee Related
- 2002-05-31 AU AU2002322026A patent/AU2002322026B2/en not_active Ceased
- 2002-05-31 EP EP02756112.5A patent/EP1401859B1/en not_active Expired - Lifetime
- 2002-05-31 CA CA2448971A patent/CA2448971C/en not_active Expired - Fee Related
-
2009
- 2009-07-14 US US12/460,110 patent/US20110014229A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2448971A1 (en) | 2002-12-27 |
| WO2002102828A3 (en) | 2003-10-09 |
| EP1401859B1 (en) | 2013-08-07 |
| KR20040003043A (ko) | 2004-01-07 |
| PL371187A1 (en) | 2005-06-13 |
| US20110014229A1 (en) | 2011-01-20 |
| CA2448971C (en) | 2013-11-26 |
| US20030044773A1 (en) | 2003-03-06 |
| AU2002322026B2 (en) | 2008-03-13 |
| JP2005501532A (ja) | 2005-01-20 |
| WO2002102828A2 (en) | 2002-12-27 |
| BR0210907A (pt) | 2004-12-21 |
| US7569383B2 (en) | 2009-08-04 |
| EP1401859A4 (en) | 2004-12-29 |
| KR100921592B1 (ko) | 2009-10-14 |
| EP1401859A2 (en) | 2004-03-31 |
| CN1551782A (zh) | 2004-12-01 |
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