ES2429688T3 - Aparatos y métodos para ajustar la entrega de fármacos - Google Patents
Aparatos y métodos para ajustar la entrega de fármacos Download PDFInfo
- Publication number
- ES2429688T3 ES2429688T3 ES02756776T ES02756776T ES2429688T3 ES 2429688 T3 ES2429688 T3 ES 2429688T3 ES 02756776 T ES02756776 T ES 02756776T ES 02756776 T ES02756776 T ES 02756776T ES 2429688 T3 ES2429688 T3 ES 2429688T3
- Authority
- ES
- Spain
- Prior art keywords
- drug
- patient
- drug delivery
- esc
- state
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000012377 drug delivery Methods 0.000 title claims abstract description 72
- 238000000034 method Methods 0.000 title description 22
- 229940079593 drug Drugs 0.000 claims abstract description 343
- 239000003814 drug Substances 0.000 claims abstract description 343
- 230000007423 decrease Effects 0.000 claims abstract description 94
- 238000001802 infusion Methods 0.000 claims abstract description 44
- 230000009471 action Effects 0.000 claims abstract description 39
- 230000036541 health Effects 0.000 claims abstract description 20
- 230000009467 reduction Effects 0.000 claims description 54
- 230000004044 response Effects 0.000 claims description 51
- 238000012360 testing method Methods 0.000 claims description 13
- 238000012544 monitoring process Methods 0.000 claims description 7
- 238000001647 drug administration Methods 0.000 claims description 5
- 238000004364 calculation method Methods 0.000 claims description 4
- 230000036772 blood pressure Effects 0.000 claims description 3
- 210000004556 brain Anatomy 0.000 claims description 3
- 108091008698 baroreceptors Proteins 0.000 claims description 2
- 210000003169 central nervous system Anatomy 0.000 claims description 2
- 210000005003 heart tissue Anatomy 0.000 claims description 2
- 210000003016 hypothalamus Anatomy 0.000 claims description 2
- 210000003734 kidney Anatomy 0.000 claims description 2
- 210000004185 liver Anatomy 0.000 claims description 2
- 210000000715 neuromuscular junction Anatomy 0.000 claims description 2
- 210000000496 pancreas Anatomy 0.000 claims description 2
- 210000002381 plasma Anatomy 0.000 claims description 2
- 210000001774 pressoreceptor Anatomy 0.000 claims description 2
- 210000002304 esc Anatomy 0.000 description 201
- 230000007704 transition Effects 0.000 description 103
- OLBCVFGFOZPWHH-UHFFFAOYSA-N propofol Chemical compound CC(C)C1=CC=CC(C(C)C)=C1O OLBCVFGFOZPWHH-UHFFFAOYSA-N 0.000 description 17
- 229960004134 propofol Drugs 0.000 description 17
- 230000008859 change Effects 0.000 description 16
- 239000010410 layer Substances 0.000 description 15
- 230000000694 effects Effects 0.000 description 14
- 239000000932 sedative agent Substances 0.000 description 10
- 230000001624 sedative effect Effects 0.000 description 9
- 238000013519 translation Methods 0.000 description 8
- 230000003109 amnesic effect Effects 0.000 description 7
- 239000000730 antalgic agent Substances 0.000 description 7
- 230000006870 function Effects 0.000 description 7
- 206010039897 Sedation Diseases 0.000 description 6
- 229940035676 analgesics Drugs 0.000 description 6
- 238000013461 design Methods 0.000 description 6
- 230000004962 physiological condition Effects 0.000 description 6
- 230000008569 process Effects 0.000 description 6
- 230000036280 sedation Effects 0.000 description 6
- 208000002193 Pain Diseases 0.000 description 5
- 230000036592 analgesia Effects 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 238000012423 maintenance Methods 0.000 description 4
- 230000036407 pain Effects 0.000 description 4
- 230000036387 respiratory rate Effects 0.000 description 4
- 231100000279 safety data Toxicity 0.000 description 4
- 208000003443 Unconsciousness Diseases 0.000 description 3
- 230000000202 analgesic effect Effects 0.000 description 3
- 238000009165 androgen replacement therapy Methods 0.000 description 3
- 238000011950 automated reagin test Methods 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 230000011514 reflex Effects 0.000 description 3
- 230000002123 temporal effect Effects 0.000 description 3
- 206010002091 Anaesthesia Diseases 0.000 description 2
- 101000637031 Homo sapiens Trafficking protein particle complex subunit 9 Proteins 0.000 description 2
- 102100031926 Trafficking protein particle complex subunit 9 Human genes 0.000 description 2
- 230000037005 anaesthesia Effects 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 239000000599 controlled substance Substances 0.000 description 2
- 230000003247 decreasing effect Effects 0.000 description 2
- 229960002428 fentanyl Drugs 0.000 description 2
- PJMPHNIQZUBGLI-UHFFFAOYSA-N fentanyl Chemical compound C=1C=CC=CC=1N(C(=O)CC)C(CC1)CCN1CCC1=CC=CC=C1 PJMPHNIQZUBGLI-UHFFFAOYSA-N 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 239000003193 general anesthetic agent Substances 0.000 description 2
- 230000000977 initiatory effect Effects 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- 238000002372 labelling Methods 0.000 description 2
- 238000012806 monitoring device Methods 0.000 description 2
- UZHSEJADLWPNLE-GRGSLBFTSA-N naloxone Chemical compound O=C([C@@H]1O2)CC[C@@]3(O)[C@H]4CC5=CC=C(O)C2=C5[C@@]13CCN4CC=C UZHSEJADLWPNLE-GRGSLBFTSA-N 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 230000000241 respiratory effect Effects 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 229910052724 xenon Inorganic materials 0.000 description 2
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 description 2
- 0 *[C@](C1)C1N=* Chemical compound *[C@](C1)C1N=* 0.000 description 1
- 229930003347 Atropine Natural products 0.000 description 1
- 208000000094 Chronic Pain Diseases 0.000 description 1
- 206010010071 Coma Diseases 0.000 description 1
- RKUNBYITZUJHSG-UHFFFAOYSA-N Hyosciamin-hydrochlorid Natural products CN1C(C2)CCC1CC2OC(=O)C(CO)C1=CC=CC=C1 RKUNBYITZUJHSG-UHFFFAOYSA-N 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- ZTVQQQVZCWLTDF-UHFFFAOYSA-N Remifentanil Chemical compound C1CN(CCC(=O)OC)CCC1(C(=O)OC)N(C(=O)CC)C1=CC=CC=C1 ZTVQQQVZCWLTDF-UHFFFAOYSA-N 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000036626 alertness Effects 0.000 description 1
- 230000003444 anaesthetic effect Effects 0.000 description 1
- 229940035674 anesthetics Drugs 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 238000013528 artificial neural network Methods 0.000 description 1
- RKUNBYITZUJHSG-SPUOUPEWSA-N atropine Chemical compound O([C@H]1C[C@H]2CC[C@@H](C1)N2C)C(=O)C(CO)C1=CC=CC=C1 RKUNBYITZUJHSG-SPUOUPEWSA-N 0.000 description 1
- 229960000396 atropine Drugs 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000001149 cognitive effect Effects 0.000 description 1
- 230000036992 cognitive tasks Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 239000012792 core layer Substances 0.000 description 1
- 238000013479 data entry Methods 0.000 description 1
- 230000003412 degenerative effect Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000003326 hypnotic agent Substances 0.000 description 1
- 230000000147 hypnotic effect Effects 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 239000002960 lipid emulsion Substances 0.000 description 1
- 238000013178 mathematical model Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 229960004127 naloxone Drugs 0.000 description 1
- 229940065778 narcan Drugs 0.000 description 1
- 239000004081 narcotic agent Substances 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000002572 peristaltic effect Effects 0.000 description 1
- 230000006461 physiological response Effects 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 108020003175 receptors Proteins 0.000 description 1
- 229960003394 remifentanil Drugs 0.000 description 1
- 230000003252 repetitive effect Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 229940125723 sedative agent Drugs 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 239000006200 vaporizer Substances 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
- A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
- G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4821—Determining level or depth of anaesthesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
- A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M2005/14208—Pressure infusion, e.g. using pumps with a programmable infusion control system, characterised by the infusion program
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0468—Liquids non-physiological
- A61M2202/048—Anaesthetics
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Primary Health Care (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Data Mining & Analysis (AREA)
- Databases & Information Systems (AREA)
- Anesthesiology (AREA)
- Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Treatment And Welfare Office Work (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30859101P | 2001-07-31 | 2001-07-31 | |
| US308591P | 2001-07-31 | ||
| PCT/US2002/024052 WO2003011358A2 (en) | 2001-07-31 | 2002-07-31 | Apparatuses and methods for titrating drug delivery |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2429688T3 true ES2429688T3 (es) | 2013-11-15 |
Family
ID=23194569
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES02756776T Expired - Lifetime ES2429688T3 (es) | 2001-07-31 | 2002-07-31 | Aparatos y métodos para ajustar la entrega de fármacos |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7229430B2 (enExample) |
| EP (1) | EP1418976B1 (enExample) |
| JP (1) | JP4495962B2 (enExample) |
| CN (1) | CN1561241B (enExample) |
| AU (1) | AU2002322761B2 (enExample) |
| CA (1) | CA2455978C (enExample) |
| ES (1) | ES2429688T3 (enExample) |
| MX (1) | MXPA04001064A (enExample) |
| WO (1) | WO2003011358A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021214368A1 (es) | 2020-04-23 | 2021-10-28 | Universidad Politécnica de Madrid | Sistema de perfusión de fármacos en lazo cerrado con control sinérgico |
Families Citing this family (148)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4903311B2 (ja) * | 1999-04-30 | 2012-03-28 | チルドレンズ ホスピタル メディカル センター | モニタされた患者パラメータにもとづく血液濾過システムおよび方法、血液濾過の監視制御装置および血液濾過用ポンプの適応制御 |
| US9741001B2 (en) | 2000-05-18 | 2017-08-22 | Carefusion 303, Inc. | Predictive medication safety |
| US9427520B2 (en) | 2005-02-11 | 2016-08-30 | Carefusion 303, Inc. | Management of pending medication orders |
| US20040172283A1 (en) * | 2003-02-09 | 2004-09-02 | Vanderveen Timothy W. | Medication management and event logger and analysis system |
| US7860583B2 (en) * | 2004-08-25 | 2010-12-28 | Carefusion 303, Inc. | System and method for dynamically adjusting patient therapy |
| US11087873B2 (en) | 2000-05-18 | 2021-08-10 | Carefusion 303, Inc. | Context-aware healthcare notification system |
| EP1316048A2 (en) | 2000-05-18 | 2003-06-04 | ALARIS Medical Systems, Inc. | Distributed remote asset and medication management drug delivery system |
| US10353856B2 (en) | 2011-03-17 | 2019-07-16 | Carefusion 303, Inc. | Scalable communication system |
| US20050171815A1 (en) * | 2003-12-31 | 2005-08-04 | Vanderveen Timothy W. | Centralized medication management system |
| US9069887B2 (en) | 2000-05-18 | 2015-06-30 | Carefusion 303, Inc. | Patient-specific medication management system |
| US10062457B2 (en) | 2012-07-26 | 2018-08-28 | Carefusion 303, Inc. | Predictive notifications for adverse patient events |
| WO2004014216A2 (en) * | 2002-08-08 | 2004-02-19 | Scott Laboratories, Inc. | Resuscitation kit system and method and pre-use protocols for a sedation and analgesia system |
| US20040049484A1 (en) * | 2002-09-11 | 2004-03-11 | Hamano Life Science Research Foundation | Method and apparatus for separating and extracting information on physiological functions |
| CN1720078B (zh) * | 2002-10-03 | 2010-06-16 | 斯科特实验室公司 | 在镇静和止痛系统中提供正交冗余监测的方法和系统 |
| US20050070812A1 (en) * | 2003-09-25 | 2005-03-31 | Donofrio William T. | Time variant vibration stimulus response for a conscious sedation system |
| US9123077B2 (en) | 2003-10-07 | 2015-09-01 | Hospira, Inc. | Medication management system |
| US8065161B2 (en) | 2003-11-13 | 2011-11-22 | Hospira, Inc. | System for maintaining drug information and communicating with medication delivery devices |
| EP1547631A1 (en) * | 2003-12-24 | 2005-06-29 | Université Libre De Bruxelles | Computer-controlled intravenous drug delivery system |
| US20060009733A1 (en) * | 2004-07-07 | 2006-01-12 | Martin James F | Bis closed loop anesthetic delivery |
| US20060042634A1 (en) * | 2004-08-31 | 2006-03-02 | Nalagatla Anil K | Device for connecting a cannula to a medical effector system |
| CN101098724B (zh) * | 2004-11-30 | 2011-04-06 | 株式会社根本杏林堂 | 机械系统 |
| CN101128229B (zh) * | 2005-02-28 | 2011-05-25 | 诺和诺德公司 | 用于改变输药速率的装置 |
| US8309057B2 (en) | 2005-06-10 | 2012-11-13 | The Invention Science Fund I, Llc | Methods for elevating neurotrophic agents |
| EP1776977A1 (en) * | 2005-10-21 | 2007-04-25 | General Electric Company | System for delivering anesthesia drugs to a patient |
| WO2008057729A2 (en) | 2006-10-16 | 2008-05-15 | Hospira, Inc. | System and method for comparing and utilizing activity information and configuration information from mulitple device management systems |
| DE102007047351A1 (de) * | 2007-10-02 | 2009-04-09 | B. Braun Melsungen Ag | System und Verfahren zur Überwachung und Regelung von Blutglukosewerten |
| US7815605B2 (en) * | 2007-11-28 | 2010-10-19 | Souter Steve R | Emergency medication pump injection system |
| US9026370B2 (en) | 2007-12-18 | 2015-05-05 | Hospira, Inc. | User interface improvements for medical devices |
| EP2244631A4 (en) * | 2008-01-15 | 2014-01-22 | Nicholas L Taro | METHOD AND APPARATUS FOR DETERMINING DETERIORATION OF RESPIRATORY FUNCTION |
| CA2715624A1 (en) * | 2008-02-20 | 2009-08-27 | Dexcom, Inc. | Continuous medicament sensor system for in vivo use |
| EP2313138B1 (en) | 2008-03-31 | 2018-09-12 | Covidien LP | System and method for determining ventilator leakage during stable periods within a breath |
| US8746248B2 (en) | 2008-03-31 | 2014-06-10 | Covidien Lp | Determination of patient circuit disconnect in leak-compensated ventilatory support |
| US8267085B2 (en) | 2009-03-20 | 2012-09-18 | Nellcor Puritan Bennett Llc | Leak-compensated proportional assist ventilation |
| US8272379B2 (en) | 2008-03-31 | 2012-09-25 | Nellcor Puritan Bennett, Llc | Leak-compensated flow triggering and cycling in medical ventilators |
| US8457706B2 (en) | 2008-05-16 | 2013-06-04 | Covidien Lp | Estimation of a physiological parameter using a neural network |
| US8551006B2 (en) | 2008-09-17 | 2013-10-08 | Covidien Lp | Method for determining hemodynamic effects |
| US8302602B2 (en) | 2008-09-30 | 2012-11-06 | Nellcor Puritan Bennett Llc | Breathing assistance system with multiple pressure sensors |
| US8527208B2 (en) * | 2008-11-17 | 2013-09-03 | Roche Diagnostics International Ag | Prandial blood glucose excursion optimization method via computation of time-varying optimal insulin profiles and system thereof |
| US8096987B2 (en) | 2008-12-05 | 2012-01-17 | The Alfred E. Mann Foundation For Scientific Research | Methods and apparatus for translating a continuous-delivery into a plurality of periodic bolus deliveries |
| US9117015B2 (en) | 2008-12-23 | 2015-08-25 | Roche Diagnostics Operations, Inc. | Management method and system for implementation, execution, data collection, and data analysis of a structured collection procedure which runs on a collection device |
| US8849458B2 (en) * | 2008-12-23 | 2014-09-30 | Roche Diagnostics Operations, Inc. | Collection device with selective display of test results, method and computer program product thereof |
| US10456036B2 (en) * | 2008-12-23 | 2019-10-29 | Roche Diabetes Care, Inc. | Structured tailoring |
| US9918635B2 (en) * | 2008-12-23 | 2018-03-20 | Roche Diabetes Care, Inc. | Systems and methods for optimizing insulin dosage |
| US10437962B2 (en) * | 2008-12-23 | 2019-10-08 | Roche Diabetes Care Inc | Status reporting of a structured collection procedure |
| EP2382568A2 (en) | 2008-12-23 | 2011-11-02 | Roche Diagnostics GmbH | Structured testing method for diagnostic or therapy support of a patient with a chronic disease and devices thereof |
| US20120011125A1 (en) | 2008-12-23 | 2012-01-12 | Roche Diagnostics Operations, Inc. | Management method and system for implementation, execution, data collection, and data analysis of a structured collection procedure which runs on a collection device |
| FR2940912B1 (fr) * | 2009-01-15 | 2013-08-16 | Hopital Foch | Systeme de pilotage de moyens d'injection d'agents d'anesthesie ou de sedation en vue de l'induction de celle-ci |
| FR2940913B1 (fr) * | 2009-01-15 | 2013-07-19 | Hopital Foch | Systeme de pilotage de moyens d'injection d'agents d'anesthesie ou de sedation |
| US10441710B2 (en) * | 2009-02-09 | 2019-10-15 | Baxter International Inc. | Infusion pump and method to prevent titration errors in infusion therapies |
| US8434479B2 (en) | 2009-02-27 | 2013-05-07 | Covidien Lp | Flow rate compensation for transient thermal response of hot-wire anemometers |
| US8424521B2 (en) | 2009-02-27 | 2013-04-23 | Covidien Lp | Leak-compensated respiratory mechanics estimation in medical ventilators |
| US8418691B2 (en) | 2009-03-20 | 2013-04-16 | Covidien Lp | Leak-compensated pressure regulated volume control ventilation |
| US8271106B2 (en) | 2009-04-17 | 2012-09-18 | Hospira, Inc. | System and method for configuring a rule set for medical event management and responses |
| US9480789B2 (en) | 2009-06-01 | 2016-11-01 | Ethicon Endo-Surgery, Inc. | Method and sedation delivery system including a pump assembly and a co-formulation of first and second drugs |
| US9242042B2 (en) * | 2009-07-21 | 2016-01-26 | Ethicon Endo-Surgery, Inc. | Drug delivery system including a drug-container holder and a pump assembly |
| US20110152770A1 (en) | 2009-07-30 | 2011-06-23 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
| US8789529B2 (en) | 2009-08-20 | 2014-07-29 | Covidien Lp | Method for ventilation |
| US8771251B2 (en) | 2009-12-17 | 2014-07-08 | Hospira, Inc. | Systems and methods for managing and delivering patient therapy through electronic drug delivery systems |
| US8532933B2 (en) | 2010-06-18 | 2013-09-10 | Roche Diagnostics Operations, Inc. | Insulin optimization systems and testing methods with adjusted exit criterion accounting for system noise associated with biomarkers |
| CN103153178A (zh) * | 2010-07-23 | 2013-06-12 | 昆腾医疗公司 | 用于结合麻醉药和止痛药的药物效应相互作用与评估麻醉期间意识水平的脑电图的装置 |
| US9055925B2 (en) | 2010-07-27 | 2015-06-16 | Carefusion 303, Inc. | System and method for reducing false alarms associated with vital-signs monitoring |
| US8676285B2 (en) | 2010-07-28 | 2014-03-18 | Covidien Lp | Methods for validating patient identity |
| EP2605813B1 (en) * | 2010-08-17 | 2018-08-01 | University of Florida Research Foundation, Inc. | Intelligent drug delivery system to optimizing medical treatment or therapy. |
| US8554298B2 (en) | 2010-09-21 | 2013-10-08 | Cividien LP | Medical ventilator with integrated oximeter data |
| US8821397B2 (en) | 2010-09-28 | 2014-09-02 | Masimo Corporation | Depth of consciousness monitor including oximeter |
| US9775545B2 (en) | 2010-09-28 | 2017-10-03 | Masimo Corporation | Magnetic electrical connector for patient monitors |
| US20120173151A1 (en) | 2010-12-29 | 2012-07-05 | Roche Diagnostics Operations, Inc. | Methods of assessing diabetes treatment protocols based on protocol complexity levels and patient proficiency levels |
| EP2663224A4 (en) | 2011-01-12 | 2017-01-11 | The Regents of The University of California | System and method for closed-loop patient-adaptive hemodynamic management |
| US8755938B2 (en) | 2011-05-13 | 2014-06-17 | Roche Diagnostics Operations, Inc. | Systems and methods for handling unacceptable values in structured collection protocols |
| US8766803B2 (en) | 2011-05-13 | 2014-07-01 | Roche Diagnostics Operations, Inc. | Dynamic data collection |
| US20130046279A1 (en) * | 2011-08-16 | 2013-02-21 | Paul J. Niklewski | User interface feature for drug delivery system |
| US9092559B2 (en) | 2011-08-16 | 2015-07-28 | Ethicon Endo-Surgery, Inc. | Drug delivery system with open architectural framework |
| CA2844807C (en) | 2011-08-19 | 2022-07-26 | Hospira, Inc. | Systems and methods for a graphical interface including a graphical representation of medical data |
| KR101820534B1 (ko) | 2011-10-07 | 2018-01-22 | 서강대학교산학협력단 | 약물 전달 속도를 정량화하는 방법, 이에 의한 mri 장치 |
| WO2013059615A1 (en) | 2011-10-21 | 2013-04-25 | Hospira, Inc. | Medical device update system |
| US9089657B2 (en) | 2011-10-31 | 2015-07-28 | Covidien Lp | Methods and systems for gating user initiated increases in oxygen concentration during ventilation |
| WO2013090709A1 (en) | 2011-12-16 | 2013-06-20 | Hospira, Inc. | System for monitoring and delivering medication to a patient and method of using the same to minimize the risks associated with automated therapy |
| ES2741725T3 (es) | 2012-03-30 | 2020-02-12 | Icu Medical Inc | Sistema de detección de aire y método para detectar aire en una bomba de un sistema de infusión |
| US9993604B2 (en) | 2012-04-27 | 2018-06-12 | Covidien Lp | Methods and systems for an optimized proportional assist ventilation |
| AU2013296555B2 (en) | 2012-07-31 | 2017-10-19 | Icu Medical, Inc. | Patient care system for critical medications |
| CN103007391B (zh) * | 2012-12-19 | 2014-12-03 | 四川大学 | 用于药液推注的预测自适应控制系统 |
| US11182728B2 (en) | 2013-01-30 | 2021-11-23 | Carefusion 303, Inc. | Medication workflow management |
| US10430554B2 (en) | 2013-05-23 | 2019-10-01 | Carefusion 303, Inc. | Medication preparation queue |
| AU2014225658B2 (en) | 2013-03-06 | 2018-05-31 | Icu Medical, Inc. | Medical device communication method |
| EP4195119A1 (en) | 2013-03-13 | 2023-06-14 | Carefusion 303 Inc. | Predictive medication safety |
| US9177108B2 (en) * | 2013-03-13 | 2015-11-03 | Carefusion 303, Inc. | Multiple infusion channel data graphical user interface |
| CA2900564C (en) | 2013-03-13 | 2022-04-26 | Carefusion 303, Inc. | Patient-specific medication management system |
| CN105144177B (zh) | 2013-04-24 | 2019-05-28 | 费森尤斯卡比德国有限公司 | 一种控制用于给患者配给药物的输注装置的控制装置 |
| CN105393277B (zh) | 2013-05-22 | 2021-07-27 | 康尔福盛303公司 | 药物工作流程管理 |
| US10046112B2 (en) | 2013-05-24 | 2018-08-14 | Icu Medical, Inc. | Multi-sensor infusion system for detecting air or an occlusion in the infusion system |
| WO2014194065A1 (en) | 2013-05-29 | 2014-12-04 | Hospira, Inc. | Infusion system and method of use which prevents over-saturation of an analog-to-digital converter |
| CA2913915C (en) | 2013-05-29 | 2022-03-29 | Hospira, Inc. | Infusion system which utilizes one or more sensors and additional information to make an air determination regarding the infusion system |
| EP2808049B1 (en) | 2013-05-31 | 2017-10-11 | Maquet Critical Care AB | Anesthetic breathing apparatus with target value control of anesthetic agent |
| US20150032053A1 (en) * | 2013-07-29 | 2015-01-29 | Medtronic, Inc. | Titration for medical infusion devices and systems |
| US20150066531A1 (en) | 2013-08-30 | 2015-03-05 | James D. Jacobson | System and method of monitoring and managing a remote infusion regimen |
| US9662436B2 (en) | 2013-09-20 | 2017-05-30 | Icu Medical, Inc. | Fail-safe drug infusion therapy system |
| US9675771B2 (en) | 2013-10-18 | 2017-06-13 | Covidien Lp | Methods and systems for leak estimation |
| US10311972B2 (en) | 2013-11-11 | 2019-06-04 | Icu Medical, Inc. | Medical device system performance index |
| TR201908852T4 (tr) | 2013-11-19 | 2019-07-22 | Icu Medical Inc | İnfüzyon pompası otomasyon sistemi ve yöntemi. |
| AU2015222800B2 (en) | 2014-02-28 | 2019-10-17 | Icu Medical, Inc. | Infusion system and method which utilizes dual wavelength optical air-in-line detection |
| US9764082B2 (en) | 2014-04-30 | 2017-09-19 | Icu Medical, Inc. | Patient care system with conditional alarm forwarding |
| JP2017517302A (ja) | 2014-05-29 | 2017-06-29 | ホスピーラ インコーポレイテッド | 構成可能閉ループ送達速度キャッチアップを有する注入システムおよびポンプ |
| US9724470B2 (en) | 2014-06-16 | 2017-08-08 | Icu Medical, Inc. | System for monitoring and delivering medication to a patient and method of using the same to minimize the risks associated with automated therapy |
| US9539383B2 (en) | 2014-09-15 | 2017-01-10 | Hospira, Inc. | System and method that matches delayed infusion auto-programs with manually entered infusion programs and analyzes differences therein |
| WO2016057553A1 (en) | 2014-10-07 | 2016-04-14 | Masimo Corporation | Modular physiological sensors |
| EP3031486A1 (en) | 2014-12-09 | 2016-06-15 | CONARIS research institute AG | Medication cartridges for optimised dosing |
| US11344668B2 (en) | 2014-12-19 | 2022-05-31 | Icu Medical, Inc. | Infusion system with concurrent TPN/insulin infusion |
| US10850024B2 (en) | 2015-03-02 | 2020-12-01 | Icu Medical, Inc. | Infusion system, device, and method having advanced infusion features |
| US10507283B2 (en) * | 2015-05-26 | 2019-12-17 | Zyno Medical, Llc | Medical pump system for improved pain management |
| AU2016267761B2 (en) | 2015-05-26 | 2021-02-11 | Icu Medical, Inc. | Infusion pump system and method with multiple drug library editor source capability |
| CN105457132A (zh) * | 2015-10-16 | 2016-04-06 | 南昌德漫多科技有限公司 | 一种注射执行及辅助装置 |
| EP3380965A1 (en) | 2015-11-23 | 2018-10-03 | Koninklijke Philips N.V. | Pulse oximeter integration for evaluating and updating a drug administration schedule using effectiveness rating |
| CN109804432B (zh) | 2016-04-15 | 2023-07-14 | 武田药品工业株式会社 | 提供药代动力学药物给药方案的方法和设备 |
| EP3452145B1 (en) * | 2016-05-02 | 2025-01-29 | Fresenius Vial SAS | Control device for controlling the administration of propofol to a patient |
| CA3023658C (en) | 2016-05-13 | 2023-03-07 | Icu Medical, Inc. | Infusion pump system and method with common line auto flush |
| ES2992878T3 (en) | 2016-06-10 | 2024-12-19 | Icu Medical Inc | Acoustic flow sensor for continuous medication flow measurements and feedback control of infusion |
| US11574737B2 (en) | 2016-07-14 | 2023-02-07 | Icu Medical, Inc. | Multi-communication path selection and security system for a medical device |
| US10896749B2 (en) | 2017-01-27 | 2021-01-19 | Shire Human Genetic Therapies, Inc. | Drug monitoring tool |
| US20190365317A1 (en) * | 2017-02-01 | 2019-12-05 | Shire Human Genetic Therapies, Inc. | Physiological sensing and therapeutic administration system and method |
| US10089055B1 (en) | 2017-12-27 | 2018-10-02 | Icu Medical, Inc. | Synchronized display of screen content on networked devices |
| US10943674B2 (en) | 2018-05-22 | 2021-03-09 | International Business Machines Corporation | Updating a clinical trial participation status based on a measure of trust dynamics |
| CA3099523A1 (en) | 2018-05-22 | 2019-11-28 | Boston Scientific Neuromodulation Corporation | Adaptive electrical neurostimulation system, method and computer readable medium for use in reducing pain perception |
| US11177039B2 (en) | 2018-05-22 | 2021-11-16 | International Business Machines Corporation | Assessing a treatment service based on a measure of trust dynamics |
| WO2019226568A1 (en) | 2018-05-22 | 2019-11-28 | Boston Scientific Neuromodulation Corporation | Adaptive chronic pain relief via implanted electrical neurostimulation |
| US11557398B2 (en) | 2018-05-22 | 2023-01-17 | International Business Machines Corporation | Delivering a chemical compound based on a measure of trust dynamics |
| US10957434B2 (en) | 2018-05-22 | 2021-03-23 | International Business Machines Corporation | Updating a prescription status based on a measure of trust dynamics |
| US10964433B2 (en) | 2018-05-22 | 2021-03-30 | International Business Machines Corporation | Assessing a medical procedure based on a measure of trust dynamics |
| US11004563B2 (en) | 2018-05-22 | 2021-05-11 | International Business Machines Corporation | Adaptive pain management and reduction based on monitoring user conditions |
| US10861592B2 (en) | 2018-07-17 | 2020-12-08 | Icu Medical, Inc. | Reducing infusion pump network congestion by staggering updates |
| US11483403B2 (en) | 2018-07-17 | 2022-10-25 | Icu Medical, Inc. | Maintaining clinical messaging during network instability |
| AU2019306492B2 (en) | 2018-07-17 | 2025-06-19 | Icu Medical, Inc. | Systems and methods for facilitating clinical messaging in a network environment |
| NZ771914A (en) | 2018-07-17 | 2023-04-28 | Icu Medical Inc | Updating infusion pump drug libraries and operational software in a networked environment |
| US10692595B2 (en) | 2018-07-26 | 2020-06-23 | Icu Medical, Inc. | Drug library dynamic version management |
| CA3107315C (en) | 2018-07-26 | 2023-01-03 | Icu Medical, Inc. | Drug library management system |
| US20220189632A1 (en) * | 2019-03-15 | 2022-06-16 | 3M Innovative Properties Company | Individualized medicine using causal models |
| CN113597305B (zh) | 2019-03-15 | 2025-03-04 | 舒万诺知识产权公司 | 使用因果模型制造生物药物 |
| AU2020267477B2 (en) | 2019-05-08 | 2025-09-18 | Icu Medical, Inc. | Threshold signature based medical device management |
| US11278671B2 (en) | 2019-12-04 | 2022-03-22 | Icu Medical, Inc. | Infusion pump with safety sequence keypad |
| US11590057B2 (en) | 2020-04-03 | 2023-02-28 | Icu Medical, Inc. | Systems, methods, and components for transferring medical fluids |
| WO2022020184A1 (en) | 2020-07-21 | 2022-01-27 | Icu Medical, Inc. | Fluid transfer devices and methods of use |
| WO2022051230A1 (en) | 2020-09-05 | 2022-03-10 | Icu Medical, Inc. | Identity-based secure medical device communications |
| US11135360B1 (en) | 2020-12-07 | 2021-10-05 | Icu Medical, Inc. | Concurrent infusion with common line auto flush |
| CN116917994A (zh) | 2021-05-27 | 2023-10-20 | 费森尤斯维尔公司 | 用于控制靶控输注的系统和方法 |
| USD1091564S1 (en) | 2021-10-13 | 2025-09-02 | Icu Medical, Inc. | Display screen or portion thereof with graphical user interface for a medical device |
| CN118176542A (zh) * | 2021-10-29 | 2024-06-11 | 费森尤斯维尔公司 | 用于通过指定诱导剂量来控制靶控输注的系统和方法 |
| ES3049764T3 (en) | 2021-10-29 | 2025-12-18 | Fresenius Vial Sas | System and method for controlling a target-controlled infusion |
| EP4444472A4 (en) | 2021-12-10 | 2025-11-19 | Icu Medical Inc | COORDINATED FLOW CONTROL MEDICAL FLUID MIXING SYSTEMS |
| CN114876780B (zh) * | 2022-05-11 | 2024-04-19 | 健帆生物科技集团股份有限公司 | 输注泵的模拟监测方法、计算机设备及存储介质 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4246894A (en) | 1979-05-24 | 1981-01-27 | Hamacher Edward N | Method and system for administering a dissociative, unconscious type of anesthesia |
| US4334526A (en) | 1979-05-24 | 1982-06-15 | Hamacher Edward N | Method for administering a dissociative, unconscious type of anesthesia |
| US4741732A (en) * | 1984-05-10 | 1988-05-03 | The University Of Melbourne | Open-loop control of drug infusion |
| US5251126A (en) * | 1990-10-29 | 1993-10-05 | Miles Inc. | Diabetes data analysis and interpretation method |
| JPH04309362A (ja) | 1991-04-08 | 1992-10-30 | Fukuda Denshi Co Ltd | 輸液システム |
| US5181285A (en) | 1991-04-19 | 1993-01-26 | American Standard Inc. | Web protection system for double sinks |
| IL104365A0 (en) * | 1992-01-31 | 1993-05-13 | Gensia Pharma | Method and apparatus for closed loop drug delivery |
| DE69329774T2 (de) | 1992-10-15 | 2001-06-21 | Baxter International Inc., Deerfield | Infusionspumpe mit elektronisch ladbarer medikamentenbibliothek |
| JPH07261990A (ja) * | 1994-03-23 | 1995-10-13 | Fujitsu Ltd | プログラム解析表示装置 |
| IE72524B1 (en) | 1994-11-04 | 1997-04-23 | Elan Med Tech | Analyte-controlled liquid delivery device and analyte monitor |
| US5895371A (en) * | 1996-08-27 | 1999-04-20 | Sabratek Corporation | Medical treatment apparatus and method |
| US5957885A (en) * | 1996-11-06 | 1999-09-28 | Alaris Medical Systems, Inc. | Oximetry monitored, patient controlled analgesia system |
| US6020954A (en) * | 1997-12-18 | 2000-02-01 | Imagestatistics, Inc. | Method and associated apparatus for the standardized grading of gemstones |
| AU750050B2 (en) * | 1998-06-03 | 2002-07-11 | Scott Laboratories, Inc. | Apparatus and method for providing a conscious patient relief from pain and anxiety associated with medical or surgical procedures |
| US7565905B2 (en) * | 1998-06-03 | 2009-07-28 | Scott Laboratories, Inc. | Apparatuses and methods for automatically assessing and monitoring a patient's responsiveness |
| RU2244506C2 (ru) * | 1998-11-30 | 2005-01-20 | Ново Нордиск А/С | Способ и система помощи пользователю в самостоятельном проведении медицинских процедур, состоящих из нескольких действий |
| US6231560B1 (en) * | 1999-02-10 | 2001-05-15 | Baxter International Inc | Method and apparatus for automatically controlling the level of medication |
| US6758810B2 (en) * | 2000-01-21 | 2004-07-06 | Medtronic Minimed, Inc. | Ambulatory medical apparatus and method using a robust communication protocol |
| DE10006044A1 (de) * | 2000-02-10 | 2001-08-16 | Roche Diagnostics Gmbh | Anordnung und Verfahren zur Dosierung eines die Blutglukose eines Patienten regulierenden Hormons |
| US6599281B1 (en) * | 2000-05-03 | 2003-07-29 | Aspect Medical Systems, Inc. | System and method for adaptive drug delivery |
-
2002
- 2002-07-31 MX MXPA04001064A patent/MXPA04001064A/es active IP Right Grant
- 2002-07-31 ES ES02756776T patent/ES2429688T3/es not_active Expired - Lifetime
- 2002-07-31 US US10/208,183 patent/US7229430B2/en not_active Expired - Lifetime
- 2002-07-31 AU AU2002322761A patent/AU2002322761B2/en not_active Ceased
- 2002-07-31 CA CA002455978A patent/CA2455978C/en not_active Expired - Lifetime
- 2002-07-31 WO PCT/US2002/024052 patent/WO2003011358A2/en not_active Ceased
- 2002-07-31 CN CN028193555A patent/CN1561241B/zh not_active Expired - Fee Related
- 2002-07-31 EP EP02756776.7A patent/EP1418976B1/en not_active Expired - Lifetime
- 2002-07-31 JP JP2003516588A patent/JP4495962B2/ja not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021214368A1 (es) | 2020-04-23 | 2021-10-28 | Universidad Politécnica de Madrid | Sistema de perfusión de fármacos en lazo cerrado con control sinérgico |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003011358A2 (en) | 2003-02-13 |
| US20030051737A1 (en) | 2003-03-20 |
| EP1418976A2 (en) | 2004-05-19 |
| JP2005509465A (ja) | 2005-04-14 |
| JP4495962B2 (ja) | 2010-07-07 |
| CN1561241A (zh) | 2005-01-05 |
| EP1418976B1 (en) | 2013-06-26 |
| CA2455978A1 (en) | 2003-02-13 |
| WO2003011358A3 (en) | 2003-08-14 |
| CA2455978C (en) | 2008-09-09 |
| AU2002322761B2 (en) | 2008-08-21 |
| MXPA04001064A (es) | 2004-05-20 |
| CN1561241B (zh) | 2013-07-10 |
| EP1418976A4 (en) | 2010-04-14 |
| US7229430B2 (en) | 2007-06-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2429688T3 (es) | Aparatos y métodos para ajustar la entrega de fármacos | |
| AU2002322761A1 (en) | Apparatuses and methods for titrating drug delivery | |
| US20240138760A1 (en) | Autonomous drug delivery system | |
| JP4970045B2 (ja) | 患者モニタリングシステムを用いる患者自己管理鎮痛法 | |
| ES2379120T3 (es) | Sistema de infusión de f�?rmacos controlado por co2. | |
| KR101298508B1 (ko) | 약물 전달 시스템을 위한 투여량 제어 | |
| ES2267767T3 (es) | Sistema de suministro adaptable de farmacos. | |
| JP7624439B2 (ja) | 薬物送達調整 | |
| van den Nieuwenhuyzen et al. | Target-controlled infusion systems: role in anaesthesia and analgesia | |
| CN101500628A (zh) | 用于pca和pcea系统优化控制的系统和方法 | |
| US20200197653A1 (en) | Multi-modal pain management device | |
| CN114129825A (zh) | 一种智能麻醉控制系统 | |
| RU2829408C1 (ru) | Регулирование доставки лекарственного средства | |
| AU2008201331B2 (en) | Co2 monitored drug infusion system | |
| CN120322828A (zh) | 基于预期程序事件的智能输液 | |
| Elliott | 6 Patient-controlled of acute pain analgesia in the management | |
| HK1136789A (en) | System and method for optimizing control of pca and pcea system | |
| HK1152499A (en) | Co2 monitored drug infusion system |