ES2423993T3 - Proteínas HLA-G y usos farmacéuticos de las mismas - Google Patents
Proteínas HLA-G y usos farmacéuticos de las mismas Download PDFInfo
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- ES2423993T3 ES2423993T3 ES09747827T ES09747827T ES2423993T3 ES 2423993 T3 ES2423993 T3 ES 2423993T3 ES 09747827 T ES09747827 T ES 09747827T ES 09747827 T ES09747827 T ES 09747827T ES 2423993 T3 ES2423993 T3 ES 2423993T3
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Classifications
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Transplantation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US112804P | 1998-12-18 | ||
| EP08168675 | 2008-11-07 | ||
| EP08168675A EP2184070A1 (en) | 2008-11-07 | 2008-11-07 | HLA-G proteins and pharmaceutical uses thereof |
| US11280408P | 2008-11-10 | 2008-11-10 | |
| PCT/EP2009/064575 WO2010052228A1 (en) | 2008-11-07 | 2009-11-04 | Hla-g proteins and pharmaceutical uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2423993T3 true ES2423993T3 (es) | 2013-09-26 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09747827T Active ES2423993T3 (es) | 2008-11-07 | 2009-11-04 | Proteínas HLA-G y usos farmacéuticos de las mismas |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20110268737A1 (enExample) |
| EP (2) | EP2184070A1 (enExample) |
| JP (1) | JP2012507994A (enExample) |
| CA (1) | CA2742517A1 (enExample) |
| DK (1) | DK2352509T3 (enExample) |
| ES (1) | ES2423993T3 (enExample) |
| PT (1) | PT2352509E (enExample) |
| WO (1) | WO2010052228A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP2443147A1 (en) * | 2009-06-18 | 2012-04-25 | Hla-G Technologies | Hla-g alpha 1 multimers and pharmaceutical uses thereof |
| EP2445934B1 (en) * | 2009-06-25 | 2014-07-16 | Commissariat à l'Énergie Atomique et aux Énergies Alternatives | Multimeric polypeptides of hla-g including at least two alpha3 domains and pharmaceutical uses thereof |
| EP3970737A1 (en) * | 2012-01-12 | 2022-03-23 | Bioverativ Therapeutics Inc. | Reducing immunogenicity against factor viii in individuals undergoing factor viii therapy |
| ES2633894T3 (es) | 2012-08-02 | 2017-09-25 | F. Hoffmann-La Roche Ag | Procedimiento para producir moléculas monoméricas y multiméricas y usos de las mismas |
| AU2013359907B2 (en) | 2012-12-11 | 2018-01-18 | Albert Einstein College Of Medicine, Inc. | Methods for high throughput receptor:ligand identification |
| CN106132428B (zh) * | 2014-01-21 | 2021-08-06 | 阿尔伯特爱因斯坦医学院 | 用于快速和全面t细胞免疫监测的细胞平台 |
| JP6416480B2 (ja) * | 2014-01-29 | 2018-10-31 | 国立大学法人北海道大学 | 関節リウマチまたはその関連疾患の予防または治療剤 |
| US9765330B1 (en) | 2015-01-09 | 2017-09-19 | Nant Holdings Ip, Llc | Compositions and methods for reduction of allograft recognition and rejection |
| US11339201B2 (en) | 2016-05-18 | 2022-05-24 | Albert Einstein College Of Medicine | Variant PD-L1 polypeptides, T-cell modulatory multimeric polypeptides, and methods of use thereof |
| KR20190019068A (ko) | 2016-05-18 | 2019-02-26 | 큐 바이오파마, 인크. | T-세포 조절 다량체 폴리펩타이드 및 이의 사용 방법 |
| NZ788807A (en) | 2016-06-03 | 2025-11-28 | Invectys | Anti hla-g specific antibodies |
| KR20190017985A (ko) * | 2016-06-14 | 2019-02-20 | 리전츠 오브 더 유니버스티 오브 미네소타 | 질환을 치료하기 위한 유전적으로 변형된 세포, 조직, 및 장기 |
| EP3548063A1 (en) | 2016-12-02 | 2019-10-09 | Bioverativ Therapeutics Inc. | Methods of inducing immune tolerance to clotting factors |
| US20190352363A1 (en) | 2016-12-22 | 2019-11-21 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| US11851471B2 (en) | 2017-01-09 | 2023-12-26 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| US20200010528A1 (en) | 2017-03-15 | 2020-01-09 | Cue Biopharma, Inc. | Methods for modulating an immune response |
| CN111886241A (zh) | 2018-01-09 | 2020-11-03 | 库尔生物制药有限公司 | 多聚体t细胞调节多肽及其使用方法 |
| JP2021080171A (ja) * | 2018-03-13 | 2021-05-27 | 国立大学法人北海道大学 | 改変タンパク質、医薬品、炎症性疾患の予防又は治療剤及び改変タンパク質の製造方法 |
| WO2021231376A2 (en) | 2020-05-12 | 2021-11-18 | Cue Biopharma, Inc. | Multimeric t-cell modulatory polypeptides and methods of use thereof |
| WO2022056014A1 (en) | 2020-09-09 | 2022-03-17 | Cue Biopharma, Inc. | Mhc class ii t-cell modulatory multimeric polypeptides for treating type 1 diabetes mellitus (t1d) and methods of use thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2717498B1 (fr) | 1994-03-18 | 1996-05-03 | Commissariat Energie Atomique | Transcrits du gène de CMH de classe I HLA-G et leurs applications. |
| ES2224603T3 (es) | 1998-02-20 | 2005-03-01 | Commissariat A L'energie Atomique | Procedimiento de seleccion de tumores que expresan hla-g sensibles a un tratamiento anticanceroso y sus aplicaciones. |
| FR2794977B1 (fr) | 1999-06-18 | 2003-10-31 | Commissariat Energie Atomique | Utilisation de compositions contenant des formes solubles d'hla-g dans le traitement de pathologies inflammatoires de la peau, et leur procede d'obtention |
| FR2810047B1 (fr) | 2000-06-13 | 2004-04-02 | Commissariat Energie Atomique | Nouvelle isoforme d'hla-g et ses applications |
| CA2551916C (en) * | 2003-12-31 | 2014-04-29 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Fc-erythropoietin fusion protein with improved pharmacokinetics |
| WO2006009809A2 (en) * | 2004-06-18 | 2006-01-26 | Regeneron Pharmaceuticals, Inc. | Vegf inhibitors for the treatment of malignant pleural effusion |
| WO2007011044A1 (ja) | 2005-07-15 | 2007-01-25 | Kyushu University, National University Corporation | ジスルフィド結合型hla-g二量体を含む医薬組成物及びジスルフィド結合型hla-g二量体の製造方法 |
| WO2007091078A2 (en) | 2006-02-10 | 2007-08-16 | Axordia Limited | Polypeptide conjugate comprising hla-g and uses thereof, stem cells transfected with hla-g |
| JP2009537145A (ja) * | 2006-05-15 | 2009-10-29 | バイラル ロジック システムズ テクノロジー コーポレーション | 免疫学的疾患および障害を治療するためのｃｄ４７と関連した組成物および方法 |
-
2008
- 2008-11-07 EP EP08168675A patent/EP2184070A1/en not_active Withdrawn
-
2009
- 2009-11-04 WO PCT/EP2009/064575 patent/WO2010052228A1/en not_active Ceased
- 2009-11-04 DK DK09747827.5T patent/DK2352509T3/da active
- 2009-11-04 ES ES09747827T patent/ES2423993T3/es active Active
- 2009-11-04 PT PT97478275T patent/PT2352509E/pt unknown
- 2009-11-04 JP JP2011535101A patent/JP2012507994A/ja active Pending
- 2009-11-04 US US13/127,788 patent/US20110268737A1/en not_active Abandoned
- 2009-11-04 EP EP09747827.5A patent/EP2352509B1/en not_active Not-in-force
- 2009-11-04 CA CA2742517A patent/CA2742517A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2012507994A (ja) | 2012-04-05 |
| DK2352509T3 (da) | 2013-08-12 |
| EP2184070A1 (en) | 2010-05-12 |
| PT2352509E (pt) | 2013-08-27 |
| EP2352509B1 (en) | 2013-05-15 |
| CA2742517A1 (en) | 2010-05-14 |
| EP2352509A1 (en) | 2011-08-10 |
| US20110268737A1 (en) | 2011-11-03 |
| WO2010052228A1 (en) | 2010-05-14 |
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