ES2415865T3 - Tapón de punto lagrimal que comprende una matriz polimérica insoluble en agua - Google Patents
Tapón de punto lagrimal que comprende una matriz polimérica insoluble en agua Download PDFInfo
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- ES2415865T3 ES2415865T3 ES07864085T ES07864085T ES2415865T3 ES 2415865 T3 ES2415865 T3 ES 2415865T3 ES 07864085 T ES07864085 T ES 07864085T ES 07864085 T ES07864085 T ES 07864085T ES 2415865 T3 ES2415865 T3 ES 2415865T3
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- 229960004752 ketorolac Drugs 0.000 description 1
- OZWKMVRBQXNZKK-UHFFFAOYSA-N ketorolac Chemical compound OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1 OZWKMVRBQXNZKK-UHFFFAOYSA-N 0.000 description 1
- 210000004561 lacrimal apparatus Anatomy 0.000 description 1
- 208000016747 lacrimal apparatus disease Diseases 0.000 description 1
- GGXICVAJURFBLW-CEYXHVGTSA-N latanoprost Chemical compound CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1CC[C@@H](O)CCC1=CC=CC=C1 GGXICVAJURFBLW-CEYXHVGTSA-N 0.000 description 1
- 229960001160 latanoprost Drugs 0.000 description 1
- 229960004771 levobetaxolol Drugs 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 238000005461 lubrication Methods 0.000 description 1
- 230000007257 malfunction Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
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- 244000005700 microbiome Species 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
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- 239000002991 molded plastic Substances 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- FABPRXSRWADJSP-MEDUHNTESA-N moxifloxacin Chemical compound COC1=C(N2C[C@H]3NCCC[C@H]3C2)C(F)=CC(C(C(C(O)=O)=C2)=O)=C1N2C1CC1 FABPRXSRWADJSP-MEDUHNTESA-N 0.000 description 1
- 229960003702 moxifloxacin Drugs 0.000 description 1
- 230000003551 muscarinic effect Effects 0.000 description 1
- QEFAQIPZVLVERP-UHFFFAOYSA-N nepafenac Chemical compound NC(=O)CC1=CC=CC(C(=O)C=2C=CC=CC=2)=C1N QEFAQIPZVLVERP-UHFFFAOYSA-N 0.000 description 1
- 229960001002 nepafenac Drugs 0.000 description 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 229960004114 olopatadine Drugs 0.000 description 1
- JBIMVDZLSHOPLA-LSCVHKIXSA-N olopatadine Chemical compound C1OC2=CC=C(CC(O)=O)C=C2C(=C/CCN(C)C)\C2=CC=CC=C21 JBIMVDZLSHOPLA-LSCVHKIXSA-N 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 229960001416 pilocarpine Drugs 0.000 description 1
- 229920002857 polybutadiene Polymers 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 239000001294 propane Substances 0.000 description 1
- 239000002510 pyrogen Substances 0.000 description 1
- 150000007660 quinolones Chemical class 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 239000000018 receptor agonist Substances 0.000 description 1
- 229940044601 receptor agonist Drugs 0.000 description 1
- 238000002278 reconstructive surgery Methods 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 239000003590 rho kinase inhibitor Substances 0.000 description 1
- 229960001487 rimexolone Drugs 0.000 description 1
- QTTRZHGPGKRAFB-OOKHYKNYSA-N rimexolone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CC)(C)[C@@]1(C)C[C@@H]2O QTTRZHGPGKRAFB-OOKHYKNYSA-N 0.000 description 1
- 238000011808 rodent model Methods 0.000 description 1
- 210000003786 sclera Anatomy 0.000 description 1
- 239000000565 sealant Substances 0.000 description 1
- 238000009958 sewing Methods 0.000 description 1
- JGMJQSFLQWGYMQ-UHFFFAOYSA-M sodium;2,6-dichloro-n-phenylaniline;acetate Chemical compound [Na+].CC([O-])=O.ClC1=CC=CC(Cl)=C1NC1=CC=CC=C1 JGMJQSFLQWGYMQ-UHFFFAOYSA-M 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000011146 sterile filtration Methods 0.000 description 1
- 238000012414 sterilization procedure Methods 0.000 description 1
- 239000002294 steroidal antiinflammatory agent Substances 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 229960004492 suprofen Drugs 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 229940126703 systemic medication Drugs 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- AODPIQQILQLWGS-GXBDJPPSSA-N tetrahydrocortisol Chemical compound C1[C@H](O)CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CC[C@@H]21 AODPIQQILQLWGS-GXBDJPPSSA-N 0.000 description 1
- 229960004605 timolol Drugs 0.000 description 1
- 229960005221 timolol maleate Drugs 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- MKPLKVHSHYCHOC-AHTXBMBWSA-N travoprost Chemical compound CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COC1=CC=CC(C(F)(F)F)=C1 MKPLKVHSHYCHOC-AHTXBMBWSA-N 0.000 description 1
- 229960002368 travoprost Drugs 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
- A61L24/0042—Materials resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00772—Apparatus for restoration of tear ducts
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Surgery (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Materials Engineering (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85783306P | 2006-11-09 | 2006-11-09 | |
| US857833P | 2006-11-09 | ||
| PCT/US2007/084018 WO2008060929A1 (en) | 2006-11-09 | 2007-11-08 | Punctal plug comprising a water-insoluble polymeric matrix |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2415865T3 true ES2415865T3 (es) | 2013-07-29 |
Family
ID=39284092
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES07864085T Active ES2415865T3 (es) | 2006-11-09 | 2007-11-08 | Tapón de punto lagrimal que comprende una matriz polimérica insoluble en agua |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20080118932A1 (enExample) |
| EP (1) | EP2086502B1 (enExample) |
| JP (1) | JP5340161B2 (enExample) |
| KR (1) | KR101409436B1 (enExample) |
| CN (1) | CN101553207B (enExample) |
| AR (1) | AR063620A1 (enExample) |
| AU (1) | AU2007319437B2 (enExample) |
| BR (1) | BRPI0718658A2 (enExample) |
| CA (1) | CA2669642A1 (enExample) |
| ES (1) | ES2415865T3 (enExample) |
| MX (1) | MX2009004857A (enExample) |
| TW (1) | TWI397426B (enExample) |
| WO (1) | WO2008060929A1 (enExample) |
| ZA (1) | ZA200902588B (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105067698B (zh) | 2009-11-05 | 2018-11-20 | 奎斯特诊断投资公司 | 用高分辨率质谱法量化胰岛素样生长因子-i和胰岛素样生长因子-ii |
| US8497079B2 (en) | 2009-12-21 | 2013-07-30 | Quest Diagnostics Investments Incorporated | Glucagon detection and quantitation by mass spectrometry |
| HUE055674T2 (hu) | 2010-10-29 | 2021-12-28 | Thermo Fisher Scientific Oy | Rendszerelrendezés automatizált mintaelõkészítõ és -elemzõ rendszerhez |
| AU2015261711B2 (en) * | 2010-10-29 | 2017-11-09 | Thermo Fisher Scientific Oy | Automated system for sample preparation and analysis |
| EP3920207A1 (en) | 2010-12-28 | 2021-12-08 | Quest Diagnostics Investments LLC | Quantitation of insulin by mass spectrometry |
| WO2013177121A2 (en) * | 2012-05-21 | 2013-11-28 | Indiana University Research And Technology Corporation | Identification and quantification of intact glycopeptides in complex samples |
| US9169331B2 (en) | 2012-12-21 | 2015-10-27 | Dionex Corporation | Separation of glycans by mixed-mode liquid chromatography |
| US9310344B2 (en) | 2013-06-14 | 2016-04-12 | Dionex Corporation | HILIC/anion-exchange/cation-exchange multimodal media |
| EP2939024B1 (en) | 2012-12-26 | 2021-04-28 | Quest Diagnostics Investments Incorporated | C peptide detection by mass spectrometry |
| US10324082B2 (en) | 2015-03-03 | 2019-06-18 | Quest Diagnostics Investments Llc | Methods for quantitation of insulin levels by mass spectrometry |
| CN108226309B (zh) * | 2016-12-13 | 2020-06-16 | 江苏奥赛康药业有限公司 | 一种右丙亚胺的分析方法 |
| FI20175244A7 (fi) * | 2017-03-17 | 2018-09-18 | Planmeca Oy | Itsekalibroiva lääketieteellinen kuvannuslaite |
| EP4617668A3 (en) | 2017-03-31 | 2025-12-24 | Quest Diagnostics Investments LLC | Methods for quantitation of insulin and c-peptide |
| WO2018232338A1 (en) * | 2017-06-16 | 2018-12-20 | AesculaTech, Inc. | Thermoresponsive polymers and uses thereof |
| CN110639066B (zh) * | 2019-09-27 | 2020-10-20 | 北京诺康达医药科技股份有限公司 | 一种可降解泪管栓及其制备方法与应用 |
| AU2024247888A1 (en) | 2023-03-31 | 2025-10-09 | Quest Diagnostics Investments Llc | Methods for quantitation of adiponectin by mass spectrometry |
| KR20250146541A (ko) * | 2024-04-01 | 2025-10-13 | 주식회사 티엠디랩 | 형상기억 고분자를 포함하는 누점 플러그 및 이의 제조방법 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3949750A (en) | 1974-10-07 | 1976-04-13 | Freeman Jerre M | Punctum plug and method for treating keratoconjunctivitis sicca (dry eye) and other ophthalmic aliments using same |
| US5575815A (en) * | 1988-08-24 | 1996-11-19 | Endoluminal Therapeutics, Inc. | Local polymeric gel therapy |
| JPH04364839A (ja) * | 1991-06-12 | 1992-12-17 | Asahi Chem Ind Co Ltd | 涙道閉鎖用ロッド |
| US5469867A (en) * | 1992-09-02 | 1995-11-28 | Landec Corporation | Cast-in place thermoplastic channel occluder |
| JP3423317B2 (ja) * | 1993-07-19 | 2003-07-07 | アンジオジェネシス テクノロジーズ インコーポレイテッド | 抗−血管形成性組成物およびそれにより被覆されたステント |
| JPH0920651A (ja) * | 1995-07-03 | 1997-01-21 | Koken Co Ltd | 注入可能な涙小管閉鎖剤 |
| US5962006A (en) * | 1997-06-17 | 1999-10-05 | Atrix Laboratories, Inc. | Polymer formulation for prevention of surgical adhesions |
| US6565874B1 (en) * | 1998-10-28 | 2003-05-20 | Atrix Laboratories | Polymeric delivery formulations of leuprolide with improved efficacy |
| JP2004505679A (ja) * | 2000-08-04 | 2004-02-26 | メデニアム インコーポレーテッド | 涙点および涙小管内インプラントのための眼用プラグ |
| US20050092910A1 (en) * | 2001-12-08 | 2005-05-05 | Scott Geromanos | Method of mass spectrometry |
| US20040068078A1 (en) * | 2001-12-12 | 2004-04-08 | Milbocker Michael T. | In situ polymerizing medical compositions |
| CA2510250A1 (en) * | 2002-12-20 | 2004-08-12 | Momenta Pharmaceuticals, Inc. | Glycan markers for diagnosing and monitoring disease |
| WO2005073732A2 (en) * | 2004-01-23 | 2005-08-11 | Amgen Inc. | Lc/ms method of analyzing high molecular weight proteins |
| WO2006031658A2 (en) * | 2004-09-10 | 2006-03-23 | Allergan, Inc. | Therapeutic lacrimal canalicular inserts and related methods |
| CA2648066C (en) * | 2006-03-31 | 2012-07-03 | Forsight Labs, Llc | Drug delivery methods, structures, and compositions for nasolacrimal system |
-
2007
- 2007-11-08 MX MX2009004857A patent/MX2009004857A/es active IP Right Grant
- 2007-11-08 JP JP2009536470A patent/JP5340161B2/ja not_active Expired - Fee Related
- 2007-11-08 WO PCT/US2007/084018 patent/WO2008060929A1/en not_active Ceased
- 2007-11-08 CA CA002669642A patent/CA2669642A1/en not_active Abandoned
- 2007-11-08 AR ARP070104979A patent/AR063620A1/es not_active Application Discontinuation
- 2007-11-08 AU AU2007319437A patent/AU2007319437B2/en not_active Ceased
- 2007-11-08 EP EP07864085.1A patent/EP2086502B1/en not_active Not-in-force
- 2007-11-08 TW TW096142199A patent/TWI397426B/zh not_active IP Right Cessation
- 2007-11-08 CN CN2007800416621A patent/CN101553207B/zh not_active Expired - Fee Related
- 2007-11-08 BR BRPI0718658-4A patent/BRPI0718658A2/pt not_active IP Right Cessation
- 2007-11-08 KR KR1020097011060A patent/KR101409436B1/ko not_active Expired - Fee Related
- 2007-11-08 ES ES07864085T patent/ES2415865T3/es active Active
- 2007-11-08 ZA ZA200902588A patent/ZA200902588B/xx unknown
- 2007-11-09 US US11/937,778 patent/US20080118932A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MX2009004857A (es) | 2009-05-21 |
| CN101553207B (zh) | 2013-01-16 |
| TWI397426B (zh) | 2013-06-01 |
| EP2086502A1 (en) | 2009-08-12 |
| TW200826972A (en) | 2008-07-01 |
| CA2669642A1 (en) | 2008-05-22 |
| US20080118932A1 (en) | 2008-05-22 |
| BRPI0718658A2 (pt) | 2013-11-19 |
| ZA200902588B (en) | 2010-06-30 |
| AU2007319437A1 (en) | 2008-05-22 |
| JP5340161B2 (ja) | 2013-11-13 |
| KR20090090320A (ko) | 2009-08-25 |
| AR063620A1 (es) | 2009-02-04 |
| AU2007319437B2 (en) | 2013-01-10 |
| CN101553207A (zh) | 2009-10-07 |
| EP2086502B1 (en) | 2013-04-17 |
| KR101409436B1 (ko) | 2014-06-24 |
| JP2010508995A (ja) | 2010-03-25 |
| WO2008060929A1 (en) | 2008-05-22 |
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