CN101553207B - 包含水不溶性聚合物基质的泪点塞 - Google Patents

包含水不溶性聚合物基质的泪点塞 Download PDF

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Publication number
CN101553207B
CN101553207B CN2007800416621A CN200780041662A CN101553207B CN 101553207 B CN101553207 B CN 101553207B CN 2007800416621 A CN2007800416621 A CN 2007800416621A CN 200780041662 A CN200780041662 A CN 200780041662A CN 101553207 B CN101553207 B CN 101553207B
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CN
China
Prior art keywords
pharmaceutical composition
channel
composition
polymer matrix
poly
Prior art date
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Expired - Fee Related
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CN2007800416621A
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English (en)
Chinese (zh)
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CN101553207A (zh
Inventor
B·阿斯加里恩
M·A·乔罕
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Alcon Research LLC
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Alcon Manufacturing Ltd
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Publication of CN101553207A publication Critical patent/CN101553207A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0042—Materials resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/00772—Apparatus for restoration of tear ducts

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Materials Engineering (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN2007800416621A 2006-11-09 2007-11-08 包含水不溶性聚合物基质的泪点塞 Expired - Fee Related CN101553207B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85783306P 2006-11-09 2006-11-09
US60/857,833 2006-11-09
PCT/US2007/084018 WO2008060929A1 (en) 2006-11-09 2007-11-08 Punctal plug comprising a water-insoluble polymeric matrix

Publications (2)

Publication Number Publication Date
CN101553207A CN101553207A (zh) 2009-10-07
CN101553207B true CN101553207B (zh) 2013-01-16

Family

ID=39284092

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2007800416621A Expired - Fee Related CN101553207B (zh) 2006-11-09 2007-11-08 包含水不溶性聚合物基质的泪点塞

Country Status (14)

Country Link
US (1) US20080118932A1 (enExample)
EP (1) EP2086502B1 (enExample)
JP (1) JP5340161B2 (enExample)
KR (1) KR101409436B1 (enExample)
CN (1) CN101553207B (enExample)
AR (1) AR063620A1 (enExample)
AU (1) AU2007319437B2 (enExample)
BR (1) BRPI0718658A2 (enExample)
CA (1) CA2669642A1 (enExample)
ES (1) ES2415865T3 (enExample)
MX (1) MX2009004857A (enExample)
TW (1) TWI397426B (enExample)
WO (1) WO2008060929A1 (enExample)
ZA (1) ZA200902588B (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105067698B (zh) 2009-11-05 2018-11-20 奎斯特诊断投资公司 用高分辨率质谱法量化胰岛素样生长因子-i和胰岛素样生长因子-ii
US8497079B2 (en) 2009-12-21 2013-07-30 Quest Diagnostics Investments Incorporated Glucagon detection and quantitation by mass spectrometry
HUE055674T2 (hu) 2010-10-29 2021-12-28 Thermo Fisher Scientific Oy Rendszerelrendezés automatizált mintaelõkészítõ és -elemzõ rendszerhez
AU2015261711B2 (en) * 2010-10-29 2017-11-09 Thermo Fisher Scientific Oy Automated system for sample preparation and analysis
EP3920207A1 (en) 2010-12-28 2021-12-08 Quest Diagnostics Investments LLC Quantitation of insulin by mass spectrometry
WO2013177121A2 (en) * 2012-05-21 2013-11-28 Indiana University Research And Technology Corporation Identification and quantification of intact glycopeptides in complex samples
US9169331B2 (en) 2012-12-21 2015-10-27 Dionex Corporation Separation of glycans by mixed-mode liquid chromatography
US9310344B2 (en) 2013-06-14 2016-04-12 Dionex Corporation HILIC/anion-exchange/cation-exchange multimodal media
EP2939024B1 (en) 2012-12-26 2021-04-28 Quest Diagnostics Investments Incorporated C peptide detection by mass spectrometry
US10324082B2 (en) 2015-03-03 2019-06-18 Quest Diagnostics Investments Llc Methods for quantitation of insulin levels by mass spectrometry
CN108226309B (zh) * 2016-12-13 2020-06-16 江苏奥赛康药业有限公司 一种右丙亚胺的分析方法
FI20175244A7 (fi) * 2017-03-17 2018-09-18 Planmeca Oy Itsekalibroiva lääketieteellinen kuvannuslaite
EP4617668A3 (en) 2017-03-31 2025-12-24 Quest Diagnostics Investments LLC Methods for quantitation of insulin and c-peptide
WO2018232338A1 (en) * 2017-06-16 2018-12-20 AesculaTech, Inc. Thermoresponsive polymers and uses thereof
CN110639066B (zh) * 2019-09-27 2020-10-20 北京诺康达医药科技股份有限公司 一种可降解泪管栓及其制备方法与应用
AU2024247888A1 (en) 2023-03-31 2025-10-09 Quest Diagnostics Investments Llc Methods for quantitation of adiponectin by mass spectrometry
KR20250146541A (ko) * 2024-04-01 2025-10-13 주식회사 티엠디랩 형상기억 고분자를 포함하는 누점 플러그 및 이의 제조방법

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3949750A (en) 1974-10-07 1976-04-13 Freeman Jerre M Punctum plug and method for treating keratoconjunctivitis sicca (dry eye) and other ophthalmic aliments using same
US5575815A (en) * 1988-08-24 1996-11-19 Endoluminal Therapeutics, Inc. Local polymeric gel therapy
JPH04364839A (ja) * 1991-06-12 1992-12-17 Asahi Chem Ind Co Ltd 涙道閉鎖用ロッド
US5469867A (en) * 1992-09-02 1995-11-28 Landec Corporation Cast-in place thermoplastic channel occluder
JP3423317B2 (ja) * 1993-07-19 2003-07-07 アンジオジェネシス テクノロジーズ インコーポレイテッド 抗−血管形成性組成物およびそれにより被覆されたステント
JPH0920651A (ja) * 1995-07-03 1997-01-21 Koken Co Ltd 注入可能な涙小管閉鎖剤
US5962006A (en) * 1997-06-17 1999-10-05 Atrix Laboratories, Inc. Polymer formulation for prevention of surgical adhesions
US6565874B1 (en) * 1998-10-28 2003-05-20 Atrix Laboratories Polymeric delivery formulations of leuprolide with improved efficacy
JP2004505679A (ja) * 2000-08-04 2004-02-26 メデニアム　インコーポレーテッド 涙点および涙小管内インプラントのための眼用プラグ
US20050092910A1 (en) * 2001-12-08 2005-05-05 Scott Geromanos Method of mass spectrometry
US20040068078A1 (en) * 2001-12-12 2004-04-08 Milbocker Michael T. In situ polymerizing medical compositions
CA2510250A1 (en) * 2002-12-20 2004-08-12 Momenta Pharmaceuticals, Inc. Glycan markers for diagnosing and monitoring disease
WO2005073732A2 (en) * 2004-01-23 2005-08-11 Amgen Inc. Lc/ms method of analyzing high molecular weight proteins
WO2006031658A2 (en) * 2004-09-10 2006-03-23 Allergan, Inc. Therapeutic lacrimal canalicular inserts and related methods
CA2648066C (en) * 2006-03-31 2012-07-03 Forsight Labs, Llc Drug delivery methods, structures, and compositions for nasolacrimal system

Also Published As

Publication number Publication date
MX2009004857A (es) 2009-05-21
TWI397426B (zh) 2013-06-01
EP2086502A1 (en) 2009-08-12
ES2415865T3 (es) 2013-07-29
TW200826972A (en) 2008-07-01
CA2669642A1 (en) 2008-05-22
US20080118932A1 (en) 2008-05-22
BRPI0718658A2 (pt) 2013-11-19
ZA200902588B (en) 2010-06-30
AU2007319437A1 (en) 2008-05-22
JP5340161B2 (ja) 2013-11-13
KR20090090320A (ko) 2009-08-25
AR063620A1 (es) 2009-02-04
AU2007319437B2 (en) 2013-01-10
CN101553207A (zh) 2009-10-07
EP2086502B1 (en) 2013-04-17
KR101409436B1 (ko) 2014-06-24
JP2010508995A (ja) 2010-03-25
WO2008060929A1 (en) 2008-05-22

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