ES2382464T3 - Mutantes de factor del crecimiento de actividad elevada - Google Patents
Mutantes de factor del crecimiento de actividad elevadaInfo
- Publication number
- ES2382464T3 ES2382464T3 ES06818642T ES06818642T ES2382464T3 ES 2382464 T3 ES2382464 T3 ES 2382464T3 ES 06818642 T ES06818642 T ES 06818642T ES 06818642 T ES06818642 T ES 06818642T ES 2382464 T3 ES2382464 T3 ES 2382464T3
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- gdf
- indicates
- protein
- alanine
- bmp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| EP05025261 | 2005-11-18 | ||
| EP05025261 | 2005-11-18 | ||
| PCT/EP2006/011074 WO2007057212A1 (en) | 2005-11-18 | 2006-11-17 | High activity growth factor mutants |
Publications (1)
| Publication Number | Publication Date |
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| ES2382464T3 true ES2382464T3 (es) | 2012-06-08 |
Family
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Family Applications (1)
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| ES06818642T Active ES2382464T3 (es) | 2005-11-18 | 2006-11-17 | Mutantes de factor del crecimiento de actividad elevada |
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| US (3) | US8188226B2 (enExample) |
| EP (1) | EP1948689B1 (enExample) |
| JP (1) | JP5654730B2 (enExample) |
| AT (1) | ATE553123T1 (enExample) |
| AU (1) | AU2006314713B2 (enExample) |
| CA (1) | CA2627370C (enExample) |
| CY (1) | CY1112877T1 (enExample) |
| DK (1) | DK1948689T3 (enExample) |
| ES (1) | ES2382464T3 (enExample) |
| PL (1) | PL1948689T3 (enExample) |
| PT (1) | PT1948689E (enExample) |
| SI (1) | SI1948689T1 (enExample) |
| WO (1) | WO2007057212A1 (enExample) |
Families Citing this family (8)
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| JP4938628B2 (ja) * | 2007-10-29 | 2012-05-23 | Ｈｏｙａ株式会社 | リン酸カルシウム系化合物、リン酸カルシウム系化合物／コラーゲン複合体及びリン酸カルシウム系細胞培養担体に付着又は吸着したエンドトキシンの抽出方法及び定量方法 |
| WO2009152085A1 (en) * | 2008-06-09 | 2009-12-17 | Wyeth | Novel bmp-12-related proteins and methods of their manufacture |
| EP2602264A1 (en) * | 2011-12-05 | 2013-06-12 | Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka mbH | GDF-5 mutant for inducing cartilage formation |
| US8956829B2 (en) | 2013-01-25 | 2015-02-17 | Warsaw Orthopedic, Inc. | Human recombinant growth and differentiaton factor-5 (rhGDF-5) |
| US9169308B2 (en) | 2013-01-25 | 2015-10-27 | Warsaw Orthopedic, Inc. | Methods and compositions of human recombinant growth and differentiation factor-5 (rhGDF-5) isolated from inclusion bodies |
| US9359417B2 (en) | 2013-01-25 | 2016-06-07 | Warsaw Orthopedic, Inc. | Cell cultures and methods of human recombinant growth and differentiaton factor-5 (rhGDF-5) |
| US9051389B2 (en) | 2013-01-25 | 2015-06-09 | Warsaw Orthopedic, Inc. | Expression conditions and methods of human recombinant growth and differentiation factor-5 (rhGDF-5) |
| US8945872B2 (en) | 2013-01-25 | 2015-02-03 | Warsaw Orthopedic, Inc. | Methods of purifying human recombinant growth and differentiation factor-5 (rhGDF-5) protein |
Family Cites Families (19)
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| US6150328A (en) * | 1986-07-01 | 2000-11-21 | Genetics Institute, Inc. | BMP products |
| US5013649A (en) * | 1986-07-01 | 1991-05-07 | Genetics Institute, Inc. | DNA sequences encoding osteoinductive products |
| DE19525416A1 (de) | 1995-07-12 | 1997-01-16 | Bioph Biotech Entw Pharm Gmbh | Verwendung von MP52 zur Behandlung und Prävention von Erkrankungen des Nervensystems |
| EP1439190A1 (en) * | 1993-01-12 | 2004-07-21 | The Johns Hopkins University School Of Medicine | Growth differentiation factor-5 |
| IL110589A0 (en) | 1993-08-10 | 1994-11-11 | Bioph Biotech Entw Pharm Gmbh | Growth/differentiation factor of the TGF- beta family |
| DK0733109T3 (da) * | 1993-12-07 | 2006-07-03 | Genetics Inst Llc | BMP-12, BMP-13 og seneinducerende præparater dermed |
| WO1996014335A1 (en) | 1994-11-07 | 1996-05-17 | The Government Of The United States Of America, Asrepresented By The Secretary, Department Of Health And Human Services | Cartilage-derived morphogenetic proteins |
| PT955313E (pt) | 1995-04-19 | 2006-07-31 | Bioph Biotech Entw Pharm Gmbh | Nova proteina e processo para a sua producao |
| JPH0931098A (ja) | 1995-07-24 | 1997-02-04 | Hoechst Japan Ltd | 新規なタンパク質ｈｍｗヒトｍｐ５２ |
| US5758328A (en) * | 1996-02-22 | 1998-05-26 | Giovannoli; Joseph | Computerized quotation system and method |
| EP1074620A1 (en) * | 1999-08-06 | 2001-02-07 | HyGene AG | Monomeric protein of the TGF-beta family |
| JPH11335398A (ja) | 1998-05-22 | 1999-12-07 | Hoechst Marion Roussel Kk | 新規な骨誘導活性を有する単量体蛋白質およびそれらからなる軟骨・骨疾患の予防および治療薬 |
| AU1024899A (en) | 1997-09-19 | 1999-04-12 | Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh | Cytokines having neurotrophic activity |
| AU778998B2 (en) * | 1998-09-22 | 2004-12-23 | University Of Maryland At Baltimore | Cystine knot growth factor mutants |
| JP2000119192A (ja) * | 1998-10-09 | 2000-04-25 | Aventis Pharma Ltd | 骨誘導因子アンタゴニスト活性を有する成熟型蛋白質 |
| US5989863A (en) * | 1998-10-14 | 1999-11-23 | Incyte Pharmaceuticals, Inc. | Human ankyrin family protein |
| WO2002021998A2 (en) | 2000-09-12 | 2002-03-21 | Axya Medical, Inc. | Apparatus and method for securing suture to bone |
| CA2441588A1 (en) * | 2001-03-23 | 2002-10-03 | Biopharm Gesellschaft Zue Biotechnologischen Entwicklung Von Pharmaka Mbh | Use of cytokines of the tgf-.beta. superfamily for the treatment and diagnosis of skin related disorders |
| US7148051B2 (en) | 2004-08-16 | 2006-12-12 | E. I. Du Pont De Nemours And Company | Production of 3-hydroxycarboxylic acid using nitrilase |
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2006
- 2006-11-17 SI SI200631358T patent/SI1948689T1/sl unknown
- 2006-11-17 AU AU2006314713A patent/AU2006314713B2/en not_active Ceased
- 2006-11-17 US US12/094,227 patent/US8188226B2/en not_active Expired - Fee Related
- 2006-11-17 PL PL06818642T patent/PL1948689T3/pl unknown
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- 2006-11-17 AT AT06818642T patent/ATE553123T1/de active
- 2006-11-17 EP EP06818642A patent/EP1948689B1/en not_active Not-in-force
- 2006-11-17 PT PT06818642T patent/PT1948689E/pt unknown
- 2006-11-17 DK DK06818642.8T patent/DK1948689T3/da active
- 2006-11-17 WO PCT/EP2006/011074 patent/WO2007057212A1/en not_active Ceased
- 2006-11-17 CA CA2627370A patent/CA2627370C/en not_active Expired - Fee Related
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2012
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2014
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Also Published As
| Publication number | Publication date |
|---|---|
| PT1948689E (pt) | 2012-05-09 |
| DK1948689T3 (da) | 2012-07-23 |
| JP2009519008A (ja) | 2009-05-14 |
| AU2006314713A1 (en) | 2007-05-24 |
| CA2627370C (en) | 2016-02-23 |
| PL1948689T3 (pl) | 2012-09-28 |
| AU2006314713B2 (en) | 2011-10-06 |
| JP5654730B2 (ja) | 2015-01-14 |
| EP1948689A1 (en) | 2008-07-30 |
| CY1112877T1 (el) | 2016-04-13 |
| US9200048B2 (en) | 2015-12-01 |
| ATE553123T1 (de) | 2012-04-15 |
| WO2007057212A1 (en) | 2007-05-24 |
| US20120322729A1 (en) | 2012-12-20 |
| US8188226B2 (en) | 2012-05-29 |
| CA2627370A1 (en) | 2007-05-24 |
| US20150057223A1 (en) | 2015-02-26 |
| SI1948689T1 (sl) | 2012-09-28 |
| US20080318860A1 (en) | 2008-12-25 |
| EP1948689B1 (en) | 2012-04-11 |
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