ES2360598T3 - Receptores de linfocitos t que se unen especificamente a vygfvracl-hla-a24. - Google Patents

Receptores de linfocitos t que se unen especificamente a vygfvracl-hla-a24. Download PDF

Info

Publication number
ES2360598T3
ES2360598T3 ES06727144T ES06727144T ES2360598T3 ES 2360598 T3 ES2360598 T3 ES 2360598T3 ES 06727144 T ES06727144 T ES 06727144T ES 06727144 T ES06727144 T ES 06727144T ES 2360598 T3 ES2360598 T3 ES 2360598T3
Authority
ES
Spain
Prior art keywords
tcr
chain
seq
tcrs
hla
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES06727144T
Other languages
English (en)
Spanish (es)
Inventor
Bent Karsten Avidex Limited JAKOBSEN
Yi Avidex Limited LI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunocore Ltd
Original Assignee
Immunocore Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunocore Ltd filed Critical Immunocore Ltd
Application granted granted Critical
Publication of ES2360598T3 publication Critical patent/ES2360598T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241Nucleotidyltransferases (2.7.7)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ES06727144T 2005-05-25 2006-05-19 Receptores de linfocitos t que se unen especificamente a vygfvracl-hla-a24. Active ES2360598T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
WOGB2005/002078 2005-05-25
GBGB0524477.7A GB0524477D0 (en) 2005-11-30 2005-11-30 Isolated T cell receptors which specifically bind to vygfvracl-hla-24
GB0524477 2005-11-30

Publications (1)

Publication Number Publication Date
ES2360598T3 true ES2360598T3 (es) 2011-06-07

Family

ID=35685841

Family Applications (1)

Application Number Title Priority Date Filing Date
ES06727144T Active ES2360598T3 (es) 2005-05-25 2006-05-19 Receptores de linfocitos t que se unen especificamente a vygfvracl-hla-a24.

Country Status (7)

Country Link
US (1) US8017730B2 (enExample)
JP (1) JP5149789B2 (enExample)
CN (1) CN101389652B (enExample)
AT (1) ATE497976T1 (enExample)
DE (1) DE602006020037D1 (enExample)
ES (1) ES2360598T3 (enExample)
GB (1) GB0524477D0 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7994298B2 (en) 2004-09-24 2011-08-09 Trustees Of Dartmouth College Chimeric NK receptor and methods for treating cancer
US9273283B2 (en) 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
US12492376B2 (en) 2009-10-29 2025-12-09 The Trustees Of Dartmouth College T-cell receptor-deficient T cell compositions
WO2011059836A2 (en) 2009-10-29 2011-05-19 Trustees Of Dartmouth College T cell receptor-deficient t cell compositions
US9833476B2 (en) 2011-08-31 2017-12-05 The Trustees Of Dartmouth College NKP30 receptor targeted therapeutics
WO2013169691A1 (en) 2012-05-07 2013-11-14 Trustees Of Dartmouth College Anti-b7-h6 antibody, fusion proteins, and methods of using the same
WO2014018863A1 (en) * 2012-07-27 2014-01-30 The Board Of Trustees Of The University Of Illinois Engineering t-cell receptors
CA2906587C (en) * 2013-03-13 2023-02-14 Health Research, Inc. Compositions and methods for use of recombinant t cell receptors for direct recognition of tumor antigen
EP3071594A4 (en) 2013-11-22 2017-05-03 The Board of Trustees of the University of Illionis Engineered high-affinity human t cell receptors
NL2014935B1 (en) 2015-06-08 2017-02-03 Applied Immune Tech Ltd T cell receptor like antibodies having fine specificity.
GB201516277D0 (en) * 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR libraries
CN106632660B (zh) * 2015-11-04 2021-01-29 广东香雪精准医疗技术有限公司 识别ny-eso-1抗原短肽的tcr
CN107987155A (zh) * 2016-10-27 2018-05-04 中国科学院广州生物医药与健康研究院 识别sage1抗原短肽的t细胞受体
CN109251243B (zh) * 2017-07-13 2021-10-19 中国科学院广州生物医药与健康研究院 一种识别sage1抗原的t细胞受体及编码该受体的核酸
EP3692058A1 (en) 2017-10-06 2020-08-12 Oslo Universitetssykehus HF Chimeric antigen receptors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6759243B2 (en) * 1998-01-20 2004-07-06 Board Of Trustees Of The University Of Illinois High affinity TCR proteins and methods
JP4317940B2 (ja) * 2001-08-31 2009-08-19 イミュノコア・リミテッド 物質
PT1558643E (pt) 2002-11-09 2009-08-24 Immunocore Ltd Apresentação de um receptor das células t
US20100068186A1 (en) 2004-05-26 2010-03-18 Avidex Limited High affinity telomerase t cell receptors
GB0427585D0 (en) 2004-12-16 2005-01-19 Avidex Ltd Assay

Also Published As

Publication number Publication date
DE602006020037D1 (de) 2011-03-24
ATE497976T1 (de) 2011-02-15
US20080292602A1 (en) 2008-11-27
JP2009506753A (ja) 2009-02-19
CN101389652A (zh) 2009-03-18
GB0524477D0 (en) 2006-01-11
JP5149789B2 (ja) 2013-02-20
CN101389652B (zh) 2013-05-29
US8017730B2 (en) 2011-09-13

Similar Documents

Publication Publication Date Title
EP1885754B1 (en) T cell receptors which specifically bind to vygfvracl-hla-a24
ES2699320T3 (es) Receptores de linfocitos T para el VIH de alta afinidad
US20210061878A1 (en) High affinity ny-eso t cell receptors
US8217144B2 (en) High affinity Melan-A T cell receptors
US20060135418A1 (en) Receptors
ES2360598T3 (es) Receptores de linfocitos t que se unen especificamente a vygfvracl-hla-a24.
JP2008514685A (ja) 治療剤に連結した、非天然型ジスルフィド鎖間結合を含有するt細胞レセプター
US20080274133A1 (en) Soluble Bifunctional Proteins
JP2008520223A (ja) ガンマ−デルタt細胞レセプター
JP5186209B2 (ja) テロメラーゼ高親和性t細胞受容体
ES2348674T3 (es) Miembros de la familia del receptor similar a ig leucociteno modificado (lir) con afinidad incrementada para mhc clase i y sus usos en la modulaciã“n de la activaciã“n de cã‰lula t.