DE602006020037D1 - Spezifisch an vygfvracl-hla-a24 bindende t-zellen-rezeptoren - Google Patents

Spezifisch an vygfvracl-hla-a24 bindende t-zellen-rezeptoren

Info

Publication number
DE602006020037D1
DE602006020037D1 DE602006020037T DE602006020037T DE602006020037D1 DE 602006020037 D1 DE602006020037 D1 DE 602006020037D1 DE 602006020037 T DE602006020037 T DE 602006020037T DE 602006020037 T DE602006020037 T DE 602006020037T DE 602006020037 D1 DE602006020037 D1 DE 602006020037D1
Authority
DE
Germany
Prior art keywords
vygfvracl
hla
cell receptors
binding
specifically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006020037T
Other languages
German (de)
English (en)
Inventor
Bent Karsten Jakobsen
Yi Avidex Limit Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunocore Ltd
Original Assignee
Immunocore Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/GB2005/002078 external-priority patent/WO2005116646A1/en
Application filed by Immunocore Ltd filed Critical Immunocore Ltd
Priority claimed from PCT/GB2006/001857 external-priority patent/WO2006125962A2/en
Publication of DE602006020037D1 publication Critical patent/DE602006020037D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE602006020037T 2005-05-25 2006-05-19 Spezifisch an vygfvracl-hla-a24 bindende t-zellen-rezeptoren Active DE602006020037D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/GB2005/002078 WO2005116646A1 (en) 2004-05-26 2005-05-25 Method for the identification of a polypeptide which binds to a given pmhc complex
GBGB0524477.7A GB0524477D0 (en) 2005-11-30 2005-11-30 Isolated T cell receptors which specifically bind to vygfvracl-hla-24
PCT/GB2006/001857 WO2006125962A2 (en) 2005-05-25 2006-05-19 T cell receptors which specifically bind to vygfvracl-hla-a24

Publications (1)

Publication Number Publication Date
DE602006020037D1 true DE602006020037D1 (de) 2011-03-24

Family

ID=35685841

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006020037T Active DE602006020037D1 (de) 2005-05-25 2006-05-19 Spezifisch an vygfvracl-hla-a24 bindende t-zellen-rezeptoren

Country Status (7)

Country Link
US (1) US8017730B2 (enExample)
JP (1) JP5149789B2 (enExample)
CN (1) CN101389652B (enExample)
AT (1) ATE497976T1 (enExample)
DE (1) DE602006020037D1 (enExample)
ES (1) ES2360598T3 (enExample)
GB (1) GB0524477D0 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7994298B2 (en) 2004-09-24 2011-08-09 Trustees Of Dartmouth College Chimeric NK receptor and methods for treating cancer
US9273283B2 (en) 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
US12492376B2 (en) 2009-10-29 2025-12-09 The Trustees Of Dartmouth College T-cell receptor-deficient T cell compositions
WO2011059836A2 (en) 2009-10-29 2011-05-19 Trustees Of Dartmouth College T cell receptor-deficient t cell compositions
US9833476B2 (en) 2011-08-31 2017-12-05 The Trustees Of Dartmouth College NKP30 receptor targeted therapeutics
WO2013169691A1 (en) 2012-05-07 2013-11-14 Trustees Of Dartmouth College Anti-b7-h6 antibody, fusion proteins, and methods of using the same
WO2014018863A1 (en) * 2012-07-27 2014-01-30 The Board Of Trustees Of The University Of Illinois Engineering t-cell receptors
CA2906587C (en) * 2013-03-13 2023-02-14 Health Research, Inc. Compositions and methods for use of recombinant t cell receptors for direct recognition of tumor antigen
EP3071594A4 (en) 2013-11-22 2017-05-03 The Board of Trustees of the University of Illionis Engineered high-affinity human t cell receptors
NL2014935B1 (en) 2015-06-08 2017-02-03 Applied Immune Tech Ltd T cell receptor like antibodies having fine specificity.
GB201516277D0 (en) * 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR libraries
CN106632660B (zh) * 2015-11-04 2021-01-29 广东香雪精准医疗技术有限公司 识别ny-eso-1抗原短肽的tcr
CN107987155A (zh) * 2016-10-27 2018-05-04 中国科学院广州生物医药与健康研究院 识别sage1抗原短肽的t细胞受体
CN109251243B (zh) * 2017-07-13 2021-10-19 中国科学院广州生物医药与健康研究院 一种识别sage1抗原的t细胞受体及编码该受体的核酸
EP3692058A1 (en) 2017-10-06 2020-08-12 Oslo Universitetssykehus HF Chimeric antigen receptors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6759243B2 (en) * 1998-01-20 2004-07-06 Board Of Trustees Of The University Of Illinois High affinity TCR proteins and methods
JP4317940B2 (ja) * 2001-08-31 2009-08-19 イミュノコア・リミテッド 物質
PT1558643E (pt) 2002-11-09 2009-08-24 Immunocore Ltd Apresentação de um receptor das células t
US20100068186A1 (en) 2004-05-26 2010-03-18 Avidex Limited High affinity telomerase t cell receptors
GB0427585D0 (en) 2004-12-16 2005-01-19 Avidex Ltd Assay

Also Published As

Publication number Publication date
ATE497976T1 (de) 2011-02-15
US20080292602A1 (en) 2008-11-27
ES2360598T3 (es) 2011-06-07
JP2009506753A (ja) 2009-02-19
CN101389652A (zh) 2009-03-18
GB0524477D0 (en) 2006-01-11
JP5149789B2 (ja) 2013-02-20
CN101389652B (zh) 2013-05-29
US8017730B2 (en) 2011-09-13

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