WO2006125962A3 - T cell receptors which specifically bind to vygfvracl-hla-a24 - Google Patents
T cell receptors which specifically bind to vygfvracl-hla-a24 Download PDFInfo
- Publication number
- WO2006125962A3 WO2006125962A3 PCT/GB2006/001857 GB2006001857W WO2006125962A3 WO 2006125962 A3 WO2006125962 A3 WO 2006125962A3 GB 2006001857 W GB2006001857 W GB 2006001857W WO 2006125962 A3 WO2006125962 A3 WO 2006125962A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- vygfvracl
- hla
- cell receptors
- specifically bind
- tcrs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/07—Nucleotidyltransferases (2.7.7)
- C12Y207/07049—RNA-directed DNA polymerase (2.7.7.49), i.e. telomerase or reverse-transcriptase
Abstract
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE602006020037T DE602006020037D1 (en) | 2005-05-25 | 2006-05-19 | Specifically to VYGFVRACL-HLA-A24 Binding T-cell Receptors |
AT06727144T ATE497976T1 (en) | 2005-05-25 | 2006-05-19 | T CELL RECEPTORS BINDING SPECIFICALLY TO VYGFVRACL-HLA-A24 |
CN2006800182554A CN101389652B (en) | 2005-05-25 | 2006-05-19 | T cell receptors which specifically bind to VYGFVRACL-HLA-A24 |
EP06727144A EP1885754B1 (en) | 2005-05-25 | 2006-05-19 | T cell receptors which specifically bind to vygfvracl-hla-a24 |
JP2008512901A JP5149789B2 (en) | 2005-05-25 | 2006-05-19 | T cell receptor that specifically binds to VYGFVRACL-HLA-A24 |
US11/915,190 US8017730B2 (en) | 2005-05-25 | 2006-05-19 | T cell receptors which specifically bind to VYGFVRACL-HLA-A24 |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/GB2005/002078 WO2005116646A1 (en) | 2004-05-26 | 2005-05-25 | Method for the identification of a polypeptide which binds to a given pmhc complex |
GBPCT/GB2005/002078 | 2005-05-25 | ||
GB0524477.7 | 2005-11-30 | ||
GBGB0524477.7A GB0524477D0 (en) | 2005-11-30 | 2005-11-30 | Isolated T cell receptors which specifically bind to vygfvracl-hla-24 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006125962A2 WO2006125962A2 (en) | 2006-11-30 |
WO2006125962A3 true WO2006125962A3 (en) | 2007-02-01 |
Family
ID=37395870
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB2006/001857 WO2006125962A2 (en) | 2005-05-25 | 2006-05-19 | T cell receptors which specifically bind to vygfvracl-hla-a24 |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP1885754B1 (en) |
WO (1) | WO2006125962A2 (en) |
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004044004A2 (en) * | 2002-11-09 | 2004-05-27 | Avidex Limited | T cell receptor display |
WO2005116075A1 (en) * | 2004-05-26 | 2005-12-08 | Avidex Ltd. | High affinity telomerase t cell receptors |
WO2006064176A1 (en) * | 2004-12-16 | 2006-06-22 | Avidex Ltd | Assays for superantigens |
-
2006
- 2006-05-19 WO PCT/GB2006/001857 patent/WO2006125962A2/en active Application Filing
- 2006-05-19 EP EP06727144A patent/EP1885754B1/en not_active Not-in-force
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004044004A2 (en) * | 2002-11-09 | 2004-05-27 | Avidex Limited | T cell receptor display |
WO2005116075A1 (en) * | 2004-05-26 | 2005-12-08 | Avidex Ltd. | High affinity telomerase t cell receptors |
WO2006064176A1 (en) * | 2004-12-16 | 2006-06-22 | Avidex Ltd | Assays for superantigens |
Non-Patent Citations (3)
Title |
---|
ARAI JUNKO ET AL: "Identification of human telomerase reverse transcriptase-derived peptides that induce HLA-A24-restricted antileukemia cytotoxic T lymphocytes", BLOOD, vol. 97, no. 9, 1 May 2001 (2001-05-01), pages 2903 - 2907, XP002408551, ISSN: 0006-4971 * |
COLE DAVID K ET AL: "Crystal structure of HLA-A*2402 complexed with a telomerase peptide", EUROPEAN JOURNAL OF IMMUNOLOGY, vol. 36, no. 1, January 2006 (2006-01-01), pages 170 - 179, XP002408552, ISSN: 0014-2980 * |
LI YI ET AL: "Directed evolution of human T-cell receptors with picomolar affinities by phage display", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, vol. 23, no. 3, March 2005 (2005-03-01), pages 349 - 354, XP002336795, ISSN: 1087-0156 * |
Also Published As
Publication number | Publication date |
---|---|
EP1885754A2 (en) | 2008-02-13 |
EP1885754B1 (en) | 2011-02-09 |
WO2006125962A2 (en) | 2006-11-30 |
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