ES2358639T3 - Composición que consiste en phy906 y agentes quimioterapéuticos. - Google Patents

Composición que consiste en phy906 y agentes quimioterapéuticos. Download PDF

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Publication number
ES2358639T3
ES2358639T3 ES01918429T ES01918429T ES2358639T3 ES 2358639 T3 ES2358639 T3 ES 2358639T3 ES 01918429 T ES01918429 T ES 01918429T ES 01918429 T ES01918429 T ES 01918429T ES 2358639 T3 ES2358639 T3 ES 2358639T3
Authority
ES
Spain
Prior art keywords
phy906
chemotherapeutic
cpt
treatment
herbal preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES01918429T
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English (en)
Spanish (es)
Inventor
Yung-Chi Cheng
Shwu-Huey Liu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yale University
Original Assignee
Yale University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yale University filed Critical Yale University
Application granted granted Critical
Publication of ES2358639T3 publication Critical patent/ES2358639T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
ES01918429T 2000-03-09 2001-03-08 Composición que consiste en phy906 y agentes quimioterapéuticos. Expired - Lifetime ES2358639T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52205500A 2000-03-09 2000-03-09
US522055 2000-03-09

Publications (1)

Publication Number Publication Date
ES2358639T3 true ES2358639T3 (es) 2011-05-12

Family

ID=24079273

Family Applications (1)

Application Number Title Priority Date Filing Date
ES01918429T Expired - Lifetime ES2358639T3 (es) 2000-03-09 2001-03-08 Composición que consiste en phy906 y agentes quimioterapéuticos.

Country Status (13)

Country Link
US (1) US7025993B2 (cg-RX-API-DMAC7.html)
EP (1) EP1401458B1 (cg-RX-API-DMAC7.html)
JP (3) JP5064630B2 (cg-RX-API-DMAC7.html)
KR (1) KR100840213B1 (cg-RX-API-DMAC7.html)
CN (1) CN100490845C (cg-RX-API-DMAC7.html)
AT (1) ATE494899T1 (cg-RX-API-DMAC7.html)
AU (1) AU4550801A (cg-RX-API-DMAC7.html)
CA (1) CA2402466C (cg-RX-API-DMAC7.html)
DE (1) DE60143857D1 (cg-RX-API-DMAC7.html)
DK (1) DK1401458T3 (cg-RX-API-DMAC7.html)
ES (1) ES2358639T3 (cg-RX-API-DMAC7.html)
TW (1) TWI324069B (cg-RX-API-DMAC7.html)
WO (1) WO2001066123A2 (cg-RX-API-DMAC7.html)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8871279B2 (en) 2000-03-09 2014-10-28 Yale University Use of the combination of PHY906 and a tyrosine kinase inhibitor as a cancer treatment regimen
US7534455B2 (en) * 2000-03-09 2009-05-19 Yale University Herbal composition PHY906 and its use in chemotherapy
EP1487434B1 (en) * 2002-03-06 2007-05-09 The Medical Research and Education Trust Botanical extract compositions with anti-cancer activity comprising isoliquiritigenin
RU2209062C1 (ru) * 2002-03-19 2003-07-27 Институт физиологии им. И.П.Павлова РАН Вещество, обладающее седативным действием
CA2556254A1 (en) * 2004-02-13 2005-08-25 Kabushiki Kaisha Yakult Honsha Aqueous solution preparation containing camptothecins
CN101730535A (zh) 2007-02-15 2010-06-09 耶鲁大学 草药组合物phy906及其在化疗中的用途
US20110111070A1 (en) 2007-10-25 2011-05-12 Yung-Chi Cheng Use of phy906 as treatment for inflammatory bowel disease and/or irritable bowel syndrome
US9778276B2 (en) * 2007-11-20 2017-10-03 Hewlett-Packard Development Company, L.P. Liquid handling device
KR100915457B1 (ko) * 2008-01-31 2009-09-04 세종대학교산학협력단 한국산 겨우살이 추출물이 함유된 미세캡슐을 유효성분으로포함하는 기능성 식품
TWI366466B (en) * 2008-05-08 2012-06-21 Ind Tech Res Inst Herbal extracts capable of inducing immune cells to produce interferon and activating toll-like receptors and the preparation thereof
WO2010035262A2 (en) * 2008-09-25 2010-04-01 Life Biotech Medical Research Ltd Herbal formulations
KR101138461B1 (ko) * 2010-02-12 2012-04-26 한국생명공학연구원 감초 추출물을 포함하는 로타바이러스 감염의 예방 또는 치료용 조성물
US8541382B2 (en) 2010-11-13 2013-09-24 Sirbal Ltd. Cardiac glycoside analogs in combination with emodin for cancer therapy
US9066974B1 (en) 2010-11-13 2015-06-30 Sirbal Ltd. Molecular and herbal combinations for treating psoriasis
US9095606B1 (en) 2010-11-13 2015-08-04 Sirbal Ltd. Molecular and herbal combinations for treating psoriasis
US8734859B1 (en) 2010-11-13 2014-05-27 Sirbal Ltd. Molecular combinations for cancer or other disease treatment
US20170049835A1 (en) 2015-07-29 2017-02-23 Sirbal Ltd. Herbal Combinations For Treating Scalp Conditions
CN102716421A (zh) * 2012-06-21 2012-10-10 中国人民解放军第三军医大学第一附属医院 治疗扁平疣的中药口服液及其制备方法
CN102698068B (zh) * 2012-07-02 2013-07-24 张秀香 一种预防化疗所致口腔黏膜炎的口腔护理液制备方法
KR101350143B1 (ko) * 2013-05-30 2014-01-16 재단법인 통합의료진흥원 반하 및 황금 생약 추출물을 포함하는 항암제로 인한 부작용의 경감용 조성물
EP3498288A1 (en) 2013-12-02 2019-06-19 Sirbal Ltd. Herbal combinations for treatment of a skin condition
CN107921282A (zh) * 2015-08-21 2018-04-17 卫理公会医院研究所 选择性抑制肠羧酸酯酶2酶活性的组合物及方法
CN109414422A (zh) * 2016-05-23 2019-03-01 耶鲁大学 使用包含phy906提取物、黄芩提取物或来自这些提取物的化合物的联合疗法改善抗免疫检查点抑制剂的治疗指数
AU2017281065B2 (en) 2016-06-22 2022-10-27 Yale University Mechanism based quality control for botanical medicine
JP7132344B2 (ja) 2018-02-28 2022-09-06 チュンアン・ユニヴァーシティ・インダストリー・アカデミック・コーペレーション・ファウンデーション 悪液質および筋損失の予防、改善または治療用組成物
WO2019204471A1 (en) * 2018-04-20 2019-10-24 Yale University Treatment of hepatitis c
WO2020255133A1 (en) * 2019-06-18 2020-12-24 The Cures Ltd. Novel therapeutic preparations comprising scutellaria barbata
CN111011136B (zh) * 2019-11-13 2021-11-02 云南中烟新材料科技有限公司 一种假秦艽的人工种植方法
JP2023504202A (ja) * 2019-12-09 2023-02-01 イエール ユニバーシティ がんの再発を予防するための組成物および方法
US20240226214A1 (en) * 2020-03-30 2024-07-11 Yale University Methods for treating inflammatory and fibrotic diseases and disorders
CN114642732A (zh) * 2020-12-21 2022-06-21 苏州普瑞森生物科技有限公司 一种组合物及其在制备治疗肿瘤的药物中的应用
CN116712507B (zh) * 2023-08-10 2023-10-20 中国人民解放军总医院第六医学中心 一种辅助乳腺癌化疗的中药组合物及其制备方法、应用

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JPS5936619A (ja) 1982-08-23 1984-02-28 Tsumura Juntendo Inc 制癌補助剤
JPS5936621A (ja) 1982-08-25 1984-02-28 Tsumura Juntendo Inc 脂肪分解促進作用阻害剤
AU655160B2 (en) 1989-11-03 1994-12-08 Alexander S. Sun Herbal treatment of malignancy
US5665393A (en) 1996-09-03 1997-09-09 International Medical Research, Inc. Herbal composition for treating prostate carcinoma
US6048847A (en) 1997-09-30 2000-04-11 Dabur Research Foundation Use of betulinic acid and its derivatives for inhibiting cancer growth and a method of monitoring this

Also Published As

Publication number Publication date
KR100840213B1 (ko) 2008-06-23
JP2004500390A (ja) 2004-01-08
CN1612743A (zh) 2005-05-04
JP2012167101A (ja) 2012-09-06
JP2014208684A (ja) 2014-11-06
DK1401458T3 (da) 2011-05-09
KR20020086627A (ko) 2002-11-18
TWI324069B (en) 2010-05-01
EP1401458A2 (en) 2004-03-31
WO2001066123A3 (en) 2004-01-08
JP5064630B2 (ja) 2012-10-31
US7025993B2 (en) 2006-04-11
CA2402466C (en) 2014-11-18
CA2402466A1 (en) 2001-09-13
US20030211180A1 (en) 2003-11-13
CN100490845C (zh) 2009-05-27
AU4550801A (en) 2001-09-17
DE60143857D1 (de) 2011-02-24
ATE494899T1 (de) 2011-01-15
EP1401458B1 (en) 2011-01-12
WO2001066123A2 (en) 2001-09-13

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