ES2358505T3 - Métodos para analizar isómeros de disulfuro de anticuerpos. - Google Patents
Métodos para analizar isómeros de disulfuro de anticuerpos. Download PDFInfo
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- ES2358505T3 ES2358505T3 ES03745158T ES03745158T ES2358505T3 ES 2358505 T3 ES2358505 T3 ES 2358505T3 ES 03745158 T ES03745158 T ES 03745158T ES 03745158 T ES03745158 T ES 03745158T ES 2358505 T3 ES2358505 T3 ES 2358505T3
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- protease
- antibody
- acetonitrile
- digestion
- organic solvent
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/624—Disulfide-stabilized antibody (dsFv)
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36635002P | 2002-03-20 | 2002-03-20 | |
| US366350P | 2002-03-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2358505T3 true ES2358505T3 (es) | 2011-05-11 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES03745158T Expired - Lifetime ES2358505T3 (es) | 2002-03-20 | 2003-03-20 | Métodos para analizar isómeros de disulfuro de anticuerpos. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20060171940A1 (enExample) |
| EP (1) | EP1495056B1 (enExample) |
| JP (2) | JP4441269B2 (enExample) |
| AT (1) | ATE500273T1 (enExample) |
| AU (1) | AU2003225900A1 (enExample) |
| DE (1) | DE60336214D1 (enExample) |
| DK (1) | DK1495056T3 (enExample) |
| ES (1) | ES2358505T3 (enExample) |
| PT (1) | PT1495056E (enExample) |
| WO (1) | WO2003080674A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0315457D0 (en) * | 2003-07-01 | 2003-08-06 | Celltech R&D Ltd | Biological products |
| GB0315450D0 (en) * | 2003-07-01 | 2003-08-06 | Celltech R&D Ltd | Biological products |
| GB0514779D0 (en) | 2005-07-19 | 2005-08-24 | Celltech R&D Ltd | Biological products |
| EP2004231A4 (en) | 2006-04-07 | 2013-07-10 | Nektar Therapeutics | CONJUGATES OF ANTI-TNF-ALPHA ANTIBODY |
| CA2765478A1 (en) * | 2009-07-09 | 2011-01-13 | F-Star Biotechnologische Forschungs- Und Entwicklungsges.M.B.H. | Stabilized immunoglobulin constant domains |
| GB201012784D0 (en) * | 2010-07-29 | 2010-09-15 | Ucb Pharma Sa | Method |
| CN119861168B (zh) * | 2024-12-30 | 2025-09-23 | 浙江大学 | 一种识别β-内酰胺类抗生素中二聚物异构体的智能分析系统及方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4849352A (en) * | 1984-10-09 | 1989-07-18 | Sullivan John B | Antibody purification process |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| GB9625640D0 (en) * | 1996-12-10 | 1997-01-29 | Celltech Therapeutics Ltd | Biological products |
| GB0013810D0 (en) * | 2000-06-06 | 2000-07-26 | Celltech Chiroscience Ltd | Biological products |
| AU2003240790A1 (en) * | 2002-05-28 | 2003-12-12 | Pharmacia Corporation | Antibody peg positional isomers, compositions comprising same, and use thereof |
-
2003
- 2003-03-20 AT AT03745158T patent/ATE500273T1/de active
- 2003-03-20 DE DE60336214T patent/DE60336214D1/de not_active Expired - Lifetime
- 2003-03-20 WO PCT/US2003/008608 patent/WO2003080674A1/en not_active Ceased
- 2003-03-20 JP JP2003578427A patent/JP4441269B2/ja not_active Expired - Lifetime
- 2003-03-20 US US10/508,711 patent/US20060171940A1/en not_active Abandoned
- 2003-03-20 AU AU2003225900A patent/AU2003225900A1/en not_active Abandoned
- 2003-03-20 EP EP03745158A patent/EP1495056B1/en not_active Expired - Lifetime
- 2003-03-20 PT PT03745158T patent/PT1495056E/pt unknown
- 2003-03-20 DK DK03745158.0T patent/DK1495056T3/da active
- 2003-03-20 ES ES03745158T patent/ES2358505T3/es not_active Expired - Lifetime
-
2009
- 2009-04-16 JP JP2009099513A patent/JP5352761B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1495056A4 (en) | 2005-09-28 |
| US20060171940A1 (en) | 2006-08-03 |
| EP1495056A1 (en) | 2005-01-12 |
| JP5352761B2 (ja) | 2013-11-27 |
| EP1495056B1 (en) | 2011-03-02 |
| PT1495056E (pt) | 2011-03-29 |
| AU2003225900A1 (en) | 2003-10-08 |
| ATE500273T1 (de) | 2011-03-15 |
| JP2009153528A (ja) | 2009-07-16 |
| DK1495056T3 (da) | 2011-05-02 |
| WO2003080674A1 (en) | 2003-10-02 |
| JP2006505497A (ja) | 2006-02-16 |
| JP4441269B2 (ja) | 2010-03-31 |
| DE60336214D1 (de) | 2011-04-14 |
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