ES2357351T3 - Procedimiento para la preparación de hidroxitirosol. - Google Patents

Procedimiento para la preparación de hidroxitirosol. Download PDF

Info

Publication number
ES2357351T3
ES2357351T3 ES08716098T ES08716098T ES2357351T3 ES 2357351 T3 ES2357351 T3 ES 2357351T3 ES 08716098 T ES08716098 T ES 08716098T ES 08716098 T ES08716098 T ES 08716098T ES 2357351 T3 ES2357351 T3 ES 2357351T3
Authority
ES
Spain
Prior art keywords
catechol
hydroxyacetyl
preparation
acid
chloroacetyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES08716098T
Other languages
English (en)
Spanish (es)
Inventor
Manfred Breuninger
Marcel Joray
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Application granted granted Critical
Publication of ES2357351T3 publication Critical patent/ES2357351T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/64—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/001—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain
    • C07C37/002—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain by transformation of a functional group, e.g. oxo, carboxyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/02—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with no unsaturation outside the aromatic ring
    • C07C39/11—Alkylated hydroxy benzenes containing also acyclically bound hydroxy groups, e.g. saligenol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/80—Separation; Purification; Stabilisation; Use of additives by liquid-liquid treatment
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/81—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Steroid Compounds (AREA)
ES08716098T 2007-03-07 2008-02-28 Procedimiento para la preparación de hidroxitirosol. Active ES2357351T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07004645 2007-03-07
EP07004645 2007-03-07

Publications (1)

Publication Number Publication Date
ES2357351T3 true ES2357351T3 (es) 2011-04-25

Family

ID=39493433

Family Applications (1)

Application Number Title Priority Date Filing Date
ES08716098T Active ES2357351T3 (es) 2007-03-07 2008-02-28 Procedimiento para la preparación de hidroxitirosol.

Country Status (7)

Country Link
US (1) US8017815B2 (de)
EP (1) EP2114846B1 (de)
CN (1) CN101641316B (de)
AT (1) ATE490953T1 (de)
DE (1) DE602008003897D1 (de)
ES (1) ES2357351T3 (de)
WO (1) WO2008107109A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103038203B (zh) * 2010-07-06 2015-06-17 广州南沙龙沙有限公司 用于制备羟基酪醇的方法
CN101891595B (zh) * 2010-07-22 2013-05-01 苏州大学 一种羟基酪醇的制备方法
EP2545811A1 (de) 2011-07-11 2013-01-16 Jackie Szerman Tragbares, mobiles Gerät zum Einsäumen von Bettwäsche, Decken und anderen Wäschestücken
CN103664536A (zh) * 2012-09-17 2014-03-26 天津科技大学 一种羟基酪醇的合成方法
DE102013203753A1 (de) 2013-03-05 2014-09-11 Wacker Chemie Ag Verfahren zur Herstellung von Hydroxytyrosol
CN103550332A (zh) * 2013-11-15 2014-02-05 天津市尖峰天然产物研究开发有限公司 一种富含羟基酪醇、枸杞多糖和苹果多酚的用于保肝的胶囊和制剂
US9427454B2 (en) * 2014-02-26 2016-08-30 Robert den Hoed Method of making liquid olive leaf extract
CN104387240B (zh) * 2014-11-19 2016-01-20 陕西嘉禾植物化工有限责任公司 一种2-(3，4-二羟基苯基)乙醇的合成方法
DE102020132795A1 (de) 2020-12-09 2022-06-09 Technische Universität Bergakademie Freiberg, Körperschaft des öffentlichen Rechts Verfahren zur biotechnologischen Herstellung von 2-Phenylethanolen aus pflanzlichen Quellen

Also Published As

Publication number Publication date
US8017815B2 (en) 2011-09-13
ATE490953T1 (de) 2010-12-15
WO2008107109A8 (en) 2010-01-14
EP2114846B1 (de) 2010-12-08
WO2008107109A1 (en) 2008-09-12
US20100324343A1 (en) 2010-12-23
CN101641316A (zh) 2010-02-03
CN101641316B (zh) 2013-08-14
EP2114846A1 (de) 2009-11-11
DE602008003897D1 (de) 2011-01-20

Similar Documents

Publication Publication Date Title
ES2357351T3 (es) Procedimiento para la preparación de hidroxitirosol.
ES2901475T3 (es) Preparación de 3-hidroxi-3,6-dimetilhexahidrobenzofuran-2-ona y derivados de la misma
WO2007009590A1 (en) Process for the preparation of phenolic compounds
EP2978748B1 (de) Verfahren und zwischenprodukte für die herstellung von pregabalin
EP0729936A1 (de) Verfahren zur Synthese der alpha-substiuierten Akrylsäuren und deren Verwendung
US20070037874A1 (en) Manufacturing process of isoflavan or isoflavene derivatives
ES2271255T3 (es) Preparacion de acidos biliares.
CN102477007B (zh) 一种制备(s)-n-叔丁氧羰基-氮杂环丁烷-2-羧酸的方法
ES2332635B2 (es) Procedimiento para la preparacion de hidroxitirosol y 3-(3,4-dihidroxifenil) propanol a partir de metilendioxibencenos.
ES2866148T3 (es) Método para producir 3,7-dimetil-7-octenol y método para producir compuesto de carboxilato de 3,7-dimetil-7-octenilo
ES2391306T3 (es) Compuestos de alcohol
Yoon et al. Syntheses and cytotoxicities of four stereoisomers of muricatacin from D-Glucose
US6653492B2 (en) Preparation of bile acids
WO2010119117A1 (en) Process for the preparation of 2,4,6-octatriene-1-oic acid and 2,4,6-octatriene-1-ol
WO2016189542A1 (en) Novel process for the preparation of sapropterin dihydrochloride and its key intermediate, l-biopterin
EP2376496B1 (de) Verfahren zur herstellung von morphin-6-glucuroniden oder von einem seiner derivate
KR100625649B1 (ko) β-히드록시부틸산 알킬 에스테르의 제조방법
EP0293127B1 (de) Verfahren zur Herstellung von Glyoxylsäure
ES2439242T3 (es) Procedimiento para preparar gabapentina
US7105705B2 (en) Hyperforin derivatives, the use thereof and formulations containing them
US20090216002A1 (en) Synthesis of hydroquinone derivatives
US2540307A (en) 3, 4-diethoxymandelic acid and process for preparing same
JPH0791223B2 (ja) 光学活性６―ｔ―ブトキシ―３，５―ジヒドロキシヘキサン酸エステルの製造法
RU2371431C2 (ru) Способ получения хинопимаровой кислоты
RU2277083C1 (ru) Способ получения 5,8-дигидрокси-2,6-7-триметокси-3-этил-1,4-нафтохинона