DE602008003897D1 - Verfahren zur herstellung von hydroxytyrosol - Google Patents

Verfahren zur herstellung von hydroxytyrosol

Info

Publication number
DE602008003897D1
DE602008003897D1 DE602008003897T DE602008003897T DE602008003897D1 DE 602008003897 D1 DE602008003897 D1 DE 602008003897D1 DE 602008003897 T DE602008003897 T DE 602008003897T DE 602008003897 T DE602008003897 T DE 602008003897T DE 602008003897 D1 DE602008003897 D1 DE 602008003897D1
Authority
DE
Germany
Prior art keywords
hydroxytyrosol
preparation
catechol
hydroxyacetyl
chloroacetyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602008003897T
Other languages
English (en)
Inventor
Manfred Breuninger
Marcel Joray
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Publication of DE602008003897D1 publication Critical patent/DE602008003897D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/64—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/001—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain
    • C07C37/002—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain by transformation of a functional group, e.g. oxo, carboxyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/02—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with no unsaturation outside the aromatic ring
    • C07C39/11—Alkylated hydroxy benzenes containing also acyclically bound hydroxy groups, e.g. saligenol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/80—Separation; Purification; Stabilisation; Use of additives by liquid-liquid treatment
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/81—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Steroid Compounds (AREA)
DE602008003897T 2007-03-07 2008-02-28 Verfahren zur herstellung von hydroxytyrosol Active DE602008003897D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07004645 2007-03-07
PCT/EP2008/001569 WO2008107109A1 (en) 2007-03-07 2008-02-28 Process for the preparation of hydroxytyrosol

Publications (1)

Publication Number Publication Date
DE602008003897D1 true DE602008003897D1 (de) 2011-01-20

Family

ID=39493433

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602008003897T Active DE602008003897D1 (de) 2007-03-07 2008-02-28 Verfahren zur herstellung von hydroxytyrosol

Country Status (7)

Country Link
US (1) US8017815B2 (de)
EP (1) EP2114846B1 (de)
CN (1) CN101641316B (de)
AT (1) ATE490953T1 (de)
DE (1) DE602008003897D1 (de)
ES (1) ES2357351T3 (de)
WO (1) WO2008107109A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103038203B (zh) * 2010-07-06 2015-06-17 广州南沙龙沙有限公司 用于制备羟基酪醇的方法
CN101891595B (zh) * 2010-07-22 2013-05-01 苏州大学 一种羟基酪醇的制备方法
EP2545811A1 (de) 2011-07-11 2013-01-16 Jackie Szerman Tragbares, mobiles Gerät zum Einsäumen von Bettwäsche, Decken und anderen Wäschestücken
CN103664536A (zh) * 2012-09-17 2014-03-26 天津科技大学 一种羟基酪醇的合成方法
DE102013203753A1 (de) 2013-03-05 2014-09-11 Wacker Chemie Ag Verfahren zur Herstellung von Hydroxytyrosol
CN103550332A (zh) * 2013-11-15 2014-02-05 天津市尖峰天然产物研究开发有限公司 一种富含羟基酪醇、枸杞多糖和苹果多酚的用于保肝的胶囊和制剂
US9427454B2 (en) * 2014-02-26 2016-08-30 Robert den Hoed Method of making liquid olive leaf extract
CN104387240B (zh) * 2014-11-19 2016-01-20 陕西嘉禾植物化工有限责任公司 一种2-(3，4-二羟基苯基)乙醇的合成方法
DE102020132795A1 (de) 2020-12-09 2022-06-09 Technische Universität Bergakademie Freiberg, Körperschaft des öffentlichen Rechts Verfahren zur biotechnologischen Herstellung von 2-Phenylethanolen aus pflanzlichen Quellen

Also Published As

Publication number Publication date
US8017815B2 (en) 2011-09-13
ATE490953T1 (de) 2010-12-15
WO2008107109A8 (en) 2010-01-14
EP2114846B1 (de) 2010-12-08
WO2008107109A1 (en) 2008-09-12
US20100324343A1 (en) 2010-12-23
CN101641316A (zh) 2010-02-03
CN101641316B (zh) 2013-08-14
EP2114846A1 (de) 2009-11-11
ES2357351T3 (es) 2011-04-25

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