ES2329270T3 - Sintesis del peptido t-1249 utilizando fragmentos intermediarios del ipeptido. - Google Patents

Sintesis del peptido t-1249 utilizando fragmentos intermediarios del ipeptido. Download PDF

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Publication number
ES2329270T3
ES2329270T3 ES05821840T ES05821840T ES2329270T3 ES 2329270 T3 ES2329270 T3 ES 2329270T3 ES 05821840 T ES05821840 T ES 05821840T ES 05821840 T ES05821840 T ES 05821840T ES 2329270 T3 ES2329270 T3 ES 2329270T3
Authority
ES
Spain
Prior art keywords
peptide
sec
reactor
nmp
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES05821840T
Other languages
English (en)
Spanish (es)
Inventor
Yeun-Kwei Han
L. Mark Hodges
David A. Johnston
Hiralal N. Khatri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2329270T3 publication Critical patent/ES2329270T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES05821840T 2004-12-30 2005-12-22 Sintesis del peptido t-1249 utilizando fragmentos intermediarios del ipeptido. Expired - Lifetime ES2329270T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64071604P 2004-12-30 2004-12-30
US640716P 2004-12-30

Publications (1)

Publication Number Publication Date
ES2329270T3 true ES2329270T3 (es) 2009-11-24

Family

ID=36001047

Family Applications (1)

Application Number Title Priority Date Filing Date
ES05821840T Expired - Lifetime ES2329270T3 (es) 2004-12-30 2005-12-22 Sintesis del peptido t-1249 utilizando fragmentos intermediarios del ipeptido.

Country Status (9)

Country Link
US (1) US7544665B2 (cg-RX-API-DMAC7.html)
EP (1) EP1856142B1 (cg-RX-API-DMAC7.html)
JP (1) JP4886703B2 (cg-RX-API-DMAC7.html)
CN (1) CN101133076B (cg-RX-API-DMAC7.html)
AT (1) ATE439371T1 (cg-RX-API-DMAC7.html)
CA (1) CA2593866C (cg-RX-API-DMAC7.html)
DE (1) DE602005016024D1 (cg-RX-API-DMAC7.html)
ES (1) ES2329270T3 (cg-RX-API-DMAC7.html)
WO (1) WO2006069729A1 (cg-RX-API-DMAC7.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007007917A (es) * 2004-12-30 2007-08-14 Hoffmann La Roche Sintesis del peptido t-20 utilizando fragmentos peptidicos intermediarios.
CA2703113A1 (en) * 2007-10-27 2009-04-30 F. Hoffmann-La Roche Ag Insulinotropic peptide synthesis using solid and solution phase combination techniques
CA2707132A1 (en) * 2007-12-11 2009-06-18 F. Hoffmann-La Roche Ag Insulinotropic peptide synthesis using solid and solution phase combination techniques
DE102008017645A1 (de) 2008-04-04 2009-10-08 Carl Zeiss Smt Ag Vorrichtung zur mikrolithographischen Projektionsbelichtung sowie Vorrichtung zur Inspektion einer Oberfläche eines Substrats

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4010560B2 (ja) 1992-07-20 2007-11-21 ドューク ユニバーシティー Ｈｉｖ複製を阻害する化合物
US6281335B1 (en) 1993-10-08 2001-08-28 Coulter Corporation Hybridoma and anti-KC-4 humanized monoclonal antibody
US6479055B1 (en) 1993-06-07 2002-11-12 Trimeris, Inc. Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission
US5464933A (en) 1993-06-07 1995-11-07 Duke University Synthetic peptide inhibitors of HIV transmission
US6281331B1 (en) * 1998-03-23 2001-08-28 Trimeris, Inc. Methods and compositions for peptide synthesis
US6469136B1 (en) * 1999-07-07 2002-10-22 Trimeris, Inc. Methods and composition for peptide synthesis
US20040209999A1 (en) * 2002-08-16 2004-10-21 Bohling James Charles Method of manufacturing polypeptides, including T-20 and T-1249, at commercial scale, and polypeptide compositions related thereto
AU2004200485A1 (en) * 2003-02-25 2004-09-09 Rohm And Haas Company Method of manufacturing T-20 and T-1249 peptides at commercial scale, and T-20 and T-1249 compositions related thereto
MX2007007917A (es) 2004-12-30 2007-08-14 Hoffmann La Roche Sintesis del peptido t-20 utilizando fragmentos peptidicos intermediarios.

Also Published As

Publication number Publication date
US7544665B2 (en) 2009-06-09
JP2008526699A (ja) 2008-07-24
CA2593866C (en) 2013-08-06
CN101133076A (zh) 2008-02-27
CA2593866A1 (en) 2006-07-06
CN101133076B (zh) 2011-07-13
US20060173163A1 (en) 2006-08-03
DE602005016024D1 (de) 2009-09-24
ATE439371T1 (de) 2009-08-15
EP1856142A1 (en) 2007-11-21
WO2006069729A1 (en) 2006-07-06
JP4886703B2 (ja) 2012-02-29
EP1856142B1 (en) 2009-08-12

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